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J. Shew · SciRah

Researcher profile · Semantic Scholar

J. Shew

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J. Shew — researcher profile on SciRah

h-index: 29
Works: 51
Citations: 7,150

Most-cited papers

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene.
J. DeCaprio, J. Ludlow, J. Figge, J. Shew +5 more
1988Cell1,483 citations
Semantic Scholar
Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation.
Phang-Lang Chen, P. Scully, J. Shew, Jean Y. J. Wang +1 more
1989Cell957 citations
Semantic Scholar
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.
H.-J. Huang, J.-K. Yee, J. Shew, P.-L. Chen +4 more
1988Science822 citations
Semantic Scholar
The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
Wen-Hwa Lee, J. Shew, F. Hong, T. Sery +4 more
1987Nature623 citations
Semantic Scholar
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.
R. Bookstein, J. Shew, Phang-Lang Chen, P. Scully +1 more
1990Science595 citations
Semantic Scholar
Inactivation of the retinoblastoma susceptibility gene in human breast cancers.
E. Lee, Ho-Ang To, J. Shew, R. Bookstein +2 more
1988Science592 citations
Semantic Scholar
Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis
Shiaw-Wei Tyan, Wen-Hung Kuo, Chun-Kai Huang, Chi Pan +4 more
2011PLoS ONE169 citations Open access
Semantic Scholar
C-terminal truncation of the retinoblastoma gene product leads to functional inactivation.
J. Shew, B. Lin, Phang-Lang Chen, Ben Y. Tseng +2 more
1990Proceedings of the National Academy of Sciences of the United States of America158 citations Open access
Semantic Scholar
Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway
Po-Hao Chang, Wendy W. Hwang-Verslues, Yi-Cheng Chang, Chun-Chin Chen +6 more
2012Cancer Research152 citations Open access
Semantic Scholar
Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy
Wendy W. Hwang-Verslues, Po-Hao Chang, Y. Jeng, Wen-Hung Kuo +13 more
2013Proceedings of the National Academy of Sciences of the United States of America150 citations Open access
Semantic Scholar
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease
Pei-Chi Wei, Yi-Hsuan Hsieh, M. Su, Xianzhi Jiang +11 more
2012Molecules and Cells150 citations Open access
Semantic Scholar
Targeting IL-17B–IL-17RB signaling with an anti–IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines
Heng-Hsiung Wu, Wendy W. Hwang-Verslues, W. Lee, Chun-Kai Huang +8 more
2015Journal of Experimental Medicine143 citations Open access
Semantic Scholar
Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate
Chun-Kai Huang, Po-Hao Chang, Wen-Hung Kuo, Chi-Long Chen +5 more
2017Nature Communications108 citations Open access
Semantic Scholar
Antibodies detecting abnormalities of the retinoblastoma susceptibility gene product (pp110RB) in osteosarcomas and synovial sarcomas.
J. Shew, N. Ling, X. Yang, O. Fodstad +1 more
1989Oncogene research97 citations
Semantic Scholar
A High Circulating Tumor Cell Count in Portal Vein Predicts Liver Metastasis From Periampullary or Pancreatic Cancer
Wen-Tien Yu, Hsun-Chuan Kuo, Bernadette Ho, Ming-Chu Chang +10 more
2016Medicine87 citations Open access
Semantic Scholar
Homozygous deletion of the retinoblastoma gene in an acute lymphoblastic leukemia (T) cell line.
Jian Cheng, P. Scully, J. Shew, Wen-Hwa Lee +2 more
1990Blood78 citations
Semantic Scholar
Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human
Yi-Cheng Chang, Yu-Jiao Yu, J. Shew, Wei-Jei Lee +6 more
2013EMBO Molecular Medicine77 citations Open access
Semantic Scholar
Breast Cancer Cells Induce Stromal Fibroblasts to Secrete ADAMTS1 for Cancer Invasion through an Epigenetic Change
Shiaw-Wei Tyan, Chih-Hung Hsu, Kai-Lin Peng, Chun-Chin Chen +6 more
2012PLoS ONE77 citations Open access
Semantic Scholar
Squalene synthase induces tumor necrosis factor receptor 1 enrichment in lipid rafts to promote lung cancer metastasis.
Yi-Fang Yang, Y. Jan, Yu-Peng Liu, Chih-Jen Yang +12 more
2014American Journal of Respiratory and Critical Care Medicine67 citations
Semantic Scholar
TGF‐β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up‐regulation of IL‐17RB
Shih-Chia Huang, Pei-Chi Wei, Wendy W. Hwang-Verslues, Wen-Hung Kuo +7 more
2017EMBO Molecular Medicine53 citations Open access
Semantic Scholar
Mitochondrial genome instability resulting from SUV3 haploinsufficiency leads to tumorigenesis and shortened lifespan
Phang-Lang Chen, Chi-Fen Chen, Yu-May Chen, Xuning Emily Guo +5 more
2012Oncogene45 citations Open access
Semantic Scholar
Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.
J. Shew, Phang-Lang Chen, R. Bookstein, E. H. P. Lee +1 more
1990Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research44 citations
Semantic Scholar
Immunohistochemical analysis of survivin expression in primary breast cancers.
J. Chu, J. Shew, Chiun-Sheng Huang
2004Journal of the Formosan Medical Association = Taiwan yi zhi43 citations
Semantic Scholar
Distinct p53-mediated G1/S checkpoint responses in two NIH3T3 subclone cells following treatment with DNA-damaging agents.
Tze-Sing Huang, Min-Liang Kuo, J. Shew, Yi-Wen Chou +1 more
1996Oncogene38 citations
Semantic Scholar
LDLR and ApoB are major genetic causes of autosomal dominant hypercholesterolemia in a Taiwanese population.
Kai-Chien Yang, Yi-Di Su, J. Shew, Kai Yang +3 more
2007Journal of the Formosan Medical Association = Taiwan yi zhi37 citations Open access
Semantic Scholar
A case of synovial sarcoma with abnormal expression of the human retinoblastoma susceptibility gene.
Arturo E. Mendoza, J. Shew, E. H. P. Lee, R. Bookstein +1 more
1988Human Pathology34 citations
Semantic Scholar
Dysregulation of HER2/HER3 Signaling Axis in Epstein-Barr Virus-Infected Breast Carcinoma Cells
Jiun-Han Lin, Ching-Hwa Tsai, J. Chu, J. Chen +2 more
2007Journal of Virology32 citations Open access
Semantic Scholar
A cis-element with mixed G-quadruplex structure of NPGPx promoter is essential for nucleolin-mediated transactivation on non-targeting siRNA stress
Pei-Chi Wei, Zi-Fu Wang, Wen-Ting Lo, M. Su +3 more
2012Nucleic Acids Research30 citations Open access
Semantic Scholar
A single Cys706 to Phe substitution in the retinoblastoma protein causes the loss of binding to SV40 T antigen.
Y. Bignon, J. Shew, D. Rappolee, S. Naylor +3 more
1990Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research29 citations
Semantic Scholar
Expression of leukemia inhibitory factor and its receptor is not altered in the decidua and chorionic villi of human anembryonic pregnancy.
Hsin-Fu Chen, Kuang-Han Chao, J. Shew, Yu-Shih Yang +1 more
2004Human Reproduction27 citations
Semantic Scholar
Application of mucin quantitative competitive reverse transcription polymerase chain reaction in assisting the diagnosis of malignant pleural effusion.
Chong-Jen Yu, J. Shew, Y. Liaw, S.-H. Kuo +2 more
2001American Journal of Respiratory and Critical Care Medicine27 citations
Semantic Scholar
p53 point mutation enhanced by hepatic regeneration in aflatoxin B1-induced rat liver tumors and preneoplastic lesions.
Chun-Chung Lee, Jer-Yuh Liu, Jen-Kun Lin, J. Chu +1 more
1998Cancer Letters24 citations
Semantic Scholar
Luteinizing Hormone Up‐Regulates the Expression of Interleukin‐1β mRNA in Human Granulosa‐Luteal Cells
Hsin-Fu Chen, Kuang-Han Chao, Li-Jung Chang, H. Ho +2 more
2000American Journal of Reproductive Immunology20 citations
Semantic Scholar
Nitric oxide modulates mitochondrial activity and apoptosis through protein S-nitrosylation for preimplantation embryo development
Tsung-Hsien Lee, Maw-Sheng Lee, Chun-Chia Huang, Hui-Mei Tsao +4 more
2013Journal of Assisted Reproduction and Genetics16 citations Open access
Semantic Scholar
Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma
L. Young, E. Lee, Ho-Ang To, R. Bookstein +6 more
1988Human Genetics14 citations
Semantic Scholar
Decreased Expression of UK114 Is Related to the Differentiation Status of Human Hepatocellular Carcinoma
Chin-Liew Chong, S. Huang, Cheng-Po Hu, Ya‐Ling Chen +7 more
2008Cancer Epidemiology, Biomarkers and Prevention13 citations Open access
Semantic Scholar
Nasopharyngeal carcinoma and retinoblastoma gene expression.
Chin-Tarng Lin, Wing-Yee Chan, Wannhsin Chen, J. Shew
1992Laboratory investigation; a journal of technical methods and pathology11 citations
Semantic Scholar
Monoclonal antibodies to hepatitis B surface antigen (HBsAg) produced by somatic cell hybrids.
S. C. Lee, J. Shew, A. C. Chang
1984Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association9 citations
Semantic Scholar
Two cytoplasmically inherited oligomycin-resistant Chinese hamster cell lines exhibit an altered mitochondrial translation product
J. Shew, G. A. Breen
1985Somatic Cell Genetics7 citations
Semantic Scholar
Dysregulation of HER 2 / HER 3 Signaling Axis in Epstein-Barr Virus-Infected Breast Carcinoma Cells
Jiun-Han Lin, Ching-Hwa Tsai, J. Chu, J. Chen +2 more
20075 citations
Semantic Scholar
Regulation of IAPs gene family by interleukin‐1α and Epstein‐Barr virus in nasopharyngeal carcinoma
Huey-Huey Chua, Te-Huei Yeh, Ying-Piao Wang, T. Sheen +3 more
2008Head and Neck4 citations
Semantic Scholar
Diverse mutations lead to inactivation of the retinoblastoma gene.
E. Y. Lee, S. Huang, J. Shew, L. A. Donoso +1 more
1991Progress in clinical and biological research3 citations
Semantic Scholar
Redox sensor NPGPx restrains ZAP70 activity and modulates T cell homeostasis.
Fang-Yi Su, Shih-Chia Huang, Pei-Chi Wei, Pang-Hung Hsu +12 more
2021Free Radical Biology & Medicine2 citations Open access
Semantic Scholar
Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress
Pei-Chi Wei, Wen-Ting Lo, M. Su, J. Shew +1 more
2011Nucleic Acids Research1 citations Open access
Semantic Scholar
Decreased Expression of UK 114 Is Related to the Differentiation Status of Human Hepatocellular Carcinoma
Chin-Liew Chong, S. Huang, Cheng-Po Hu, Ya‐Ling Chen +7 more
20081 citations
Semantic Scholar
Protein kinases derived from the conditioned media of human peripheral blood mononuclear cells.
Sheng-Chung Lee, J. Shew, F. Chang, A. C. Chang
1984Cellular Immunology1 citations
Semantic Scholar
SQS promotes metastasis through altered cholesterol contents and recruiting TNFR1 to lipid rafts for NFκB activation in lung cancer (405.1)
Yi-Fang Yang, Y. Jan, Chih-Jen Yang, Yu-Peng Liu +8 more
20140 citations
Semantic Scholar
Squalene Synthase 引發 Tumor Necrosis Factor Receptor 1增加 Lipid Rafts to 增強肺癌轉移
Yi-Fang Yang, Y. Jan, Yu-Peng Liu, Zhi-Ren Yang +17 more
20140 citations
Semantic Scholar
Corrections to the LDLR gene polymorphisms identified in a Taiwanese population.
Kai-Chien Yang, Yi-Di Su, J. Shew, Kai Yang +3 more
2008Journal of the Formosan Medical Association = Taiwan yi zhi0 citations Open access
Semantic Scholar
Suppression of Tumorigenicity of Human Hepatocellular Carcinoma Cells by Replacing a Mutated P53 Gene
J. Shew
20000 citations
Semantic Scholar

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