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T. Sun · SciRah

Researcher profile · Semantic Scholar

T. Sun

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T. Sun — researcher profile on SciRah

h-index: 74
Works: 176
Citations: 20K

Most-cited papers

Corneal epithelial stem cells at the limbus: looking at some old problems from a new angle.
R. Lavker, Scheffer C. G. Tseng, T. Sun
2004Experimental Eye Research351 citations
Semantic Scholar
Uroplakins in Urothelial Biology, Function and Disease
Xue-Ru Wu, X. Kong, A. Pellicer, G. Kreibich +1 more
2009Kidney International343 citations Open access
Semantic Scholar
Proximal location of mouse prostate epithelial stem cells
A. Tsujimura, Y. Koikawa, S. Salm, T. Takao +6 more
2002Journal of Cell Biology324 citations Open access
Semantic Scholar
Role of membrane proteins in permeability barrier function: uroplakin ablation elevates urothelial permeability.
P. Hu, S. Meyers, Feng-Xia Liang, Fang-Ming Deng +3 more
2002AJP - Renal Physiology246 citations
Semantic Scholar
Hair follicle stem cells.
R. Lavker, T. Sun, H. Oshima, Y. Barrandon +8 more
2003Journal of Investigative Dermatology Symposium Proceedings238 citations Open access
Semantic Scholar
Compositional differences between infant and adult human corneal basement membranes.
Andrea Kabosova, D. Azar, Gregory A. Bannikov, Kevin P. Campbell +18 more
2007Investigative Ophthalmology and Visual Science193 citations Open access
Semantic Scholar
Overexpression of NGF in mouse urothelium leads to neuronal hyperinnervation, pelvic sensitivity, and changes in urinary bladder function.
B. Schnegelsberg, T. Sun, G. Cain, A. Bhattacharya +4 more
2010American Journal of Physiology. Regulatory Integrative and Comparative Physiology180 citations Open access
Semantic Scholar
Bacteria-Induced Uroplakin Signaling Mediates Bladder Response to Infection
P. Thumbikat, R. E. Berry, Ge Zhou, B. Billips +5 more
2009PLoS Pathogens176 citations Open access
Semantic Scholar
Roles of uroplakins in plaque formation, umbrella cell enlargement, and urinary tract diseases
Xiang-Tien Kong, Fang-Ming Deng, P. Hu, Feng-Xia Liang +8 more
2004Journal of Cell Biology171 citations Open access
Semantic Scholar
Anatomy and Physiology of the Urinary Tract: Relation to Host Defense and Microbial Infection
D. Hickling, T. Sun, Xue-Ru Wu
2015Microbiology spectrum162 citations Open access
Semantic Scholar
Role of Ha-ras activation in superficial papillary pathway of urothelial tumor formation
Zhong-Ting Zhang, J. Pak, Hongying Huang, E. Shapiro +3 more
2001Oncogene162 citations
Semantic Scholar
Interpreting epithelial cancer biology in the context of stem cells: tumor properties and therapeutic implications.
Stanley J. Miller, R. Lavker, T. Sun
2005Biochimica et Biophysica Acta145 citations
Semantic Scholar
Appearance of new tetraspanin genes during vertebrate evolution.
A. García-España, Pei-Jung Chung, I. Sarkar, Eric O. Stiner +2 more
2008Genomics139 citations Open access
Semantic Scholar
Structural basis for tetraspanin functions as revealed by the cryo-EM structure of uroplakin complexes at 6-Å resolution
Guangwei Min, Huai-Bin Wang, T. Sun, X. Kong
2006Journal of Cell Biology139 citations Open access
Semantic Scholar
Distinct Glycan Structures of Uroplakins Ia and Ib
Bo Xie, Ge Zhou, Shiu-Yung Chan, E. Shapiro +4 more
2006Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Specific heterodimer formation is a prerequisite for uroplakins to exit from the endoplasmic reticulum.
L. Tu, T. Sun, G. Kreibich
2002Molecular Biology of the Cell130 citations Open access
Semantic Scholar
Novel Blood Biomarkers of Human Urinary Bladder Cancer
I. Osman, D. Bajorin, T. Sun, H. Zhong +6 more
2006Clinical Cancer Research128 citations
Semantic Scholar
Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis.
L. Mo, Xiao-Yong Zheng, Hongying Huang, E. Shapiro +4 more
2007Journal of Clinical Investigation120 citations Open access
Semantic Scholar
De novo Uroplakin IIIa heterozygous mutations cause human renal adysplasia leading to severe kidney failure.
D. Jenkins, M. Bitner-Glindzicz, S. Malcolm, C. A. Hu +8 more
2005Journal of the American Society of Nephrology115 citations
Semantic Scholar
Assembly of urothelial plaques: tetraspanin function in membrane protein trafficking.
C. A. Hu, Feng-Xia Liang, Ge Zhou, L. Tu +4 more
2005Molecular Biology of the Cell114 citations Open access
Semantic Scholar
Overexpression of epidermal growth factor receptor in urothelium elicits urothelial hyperplasia and promotes bladder tumor growth.
Jin Cheng, Hongying Huang, Zhong-Ting Zhang, E. Shapiro +3 more
2002Cancer Research103 citations
Semantic Scholar
Structural basis of urothelial permeability barrier function as revealed by Cryo-EM studies of the 16 nm uroplakin particle
Guangwei Min, Ge Zhou, M. Schapira, T. Sun +1 more
2003Journal of Cell Science101 citations Open access
Semantic Scholar
Uroplakin IIIb, a urothelial differentiation marker, dimerizes with uroplakin Ib as an early step of urothelial plaque assembly
Fang-Ming Deng, Feng-Xia Liang, L. Tu, K. Resing +7 more
2002Journal of Cell Biology101 citations Open access
Semantic Scholar
Brenner tumors but not transitional cell carcinomas of the ovary show urothelial differentiation: immunohistochemical staining of urothelial markers, including cytokeratins and uroplakins
I. Riedel, B. Czernobilsky, B. Lifschitz-mercer, L. Roth +3 more
2001Virchows Archiv101 citations
Semantic Scholar
Corneal epithelial stem cells: past, present, and future.
T. Sun, R. Lavker
2004Journal of Investigative Dermatology Symposium Proceedings95 citations Open access
Semantic Scholar
Location of corneal epithelial stem cells
T. Sun, Scheffer C. G. Tseng, R. Lavker
2010Nature94 citations
Semantic Scholar
Altered phenotype of cultured urothelial and other stratified epithelial cells: implications for wound healing.
T. Sun
2006AJP - Renal Physiology93 citations
Semantic Scholar
A survivin gene signature predicts aggressive tumor behavior.
Whitney Salz, D. Eisenberg, J. Plescia, D. Garlick +4 more
2005Cancer Research92 citations Open access
Semantic Scholar
Tailbud-derived mesenchyme promotes urinary tract segmentation via BMP4 signaling
Andrea Brenner-Anantharam, Cristina Cebrián, Richard Guillaume, Romulo Hurtado +2 more
2007Development87 citations Open access
Semantic Scholar
Localization of uroplakin Ia, the urothelial receptor for bacterial adhesin FimH, on the six inner domains of the 16 nm urothelial plaque particle.
Guangwei Min, M. Stolz, Ge Zhou, F. Liang +6 more
2002Journal of Molecular Biology85 citations
Semantic Scholar
Rab27b is associated with fusiform vesicles and may be involved in targeting uroplakins to urothelial apical membranes
Yanru Chen, Xue-Mei Guo, Fang-Ming Deng, Fengzhi Liang +6 more
2003Proceedings of the National Academy of Sciences of the United States of America80 citations Open access
Semantic Scholar
Persistent uroplakin expression in advanced urothelial carcinomas: implications in urothelial tumor progression and clinical outcome.
Hongying Huang, S. Shariat, T. Sun, H. Lepor +5 more
2007Human Pathology79 citations Open access
Semantic Scholar
Proteus mirabilis fimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation
Jessica N. Schaffer, Allison N. Norsworthy, T. Sun, Melanie M. Pearson
2016Proceedings of the National Academy of Sciences of the United States of America78 citations Open access
Semantic Scholar
The histone deacetylase inhibitor belinostat (PXD101) suppresses bladder cancer cell growth in vitro and in vivo
M. Buckley, J. Yoon, H. Yee, L. Chiriboga +7 more
2007Journal of Translational Medicine78 citations Open access
Semantic Scholar
Cellular basis of urothelial squamous metaplasia
Feng-Xia Liang, M. Bosland, Hongying Huang, R. Romih +5 more
2005Journal of Cell Biology77 citations Open access
Semantic Scholar
Deficiency of pRb Family Proteins and p53 in Invasive Urothelial Tumorigenesis
F. He, L. Mo, Xiao-Yong Zheng, Chang-Kun Hu +4 more
2009Cancer Research76 citations Open access
Semantic Scholar
Formation of asymmetric unit membrane during urothelial differentiation
T. Sun, Haiping Zhao, J. Provet, U. Aebi +1 more
2004Molecular Biology Reports72 citations
Semantic Scholar
Dominant role of CDKN2B/p15INK4B of 9p21.3 tumor suppressor hub in inhibition of cell-cycle and glycolysis
Yong Xia, Yan Liu, Chao Yang, D. Simeone +5 more
2021Nature Communications65 citations Open access
Semantic Scholar
p53 deficiency provokes urothelial proliferation and synergizes with activated Ha-ras in promoting urothelial tumorigenesis
Jing Gao, Hongying Huang, J. Pak, Jin Cheng +5 more
2004Oncogene64 citations Open access
Semantic Scholar
PKM2 is essential for bladder cancer growth and maintenance
Yong Xia, Xing Wang, Yan Liu, E. Shapiro +4 more
2021Cancer Research59 citations Open access
Semantic Scholar
Uropathogenic E. coli adhesin-induced host cell receptor conformational changes: implications in transmembrane signaling transduction
Huai-Bin Wang, Guangwei Min, R. Glockshuber, T. Sun +1 more
2009Journal of Molecular Biology57 citations Open access
Semantic Scholar
Origin of the tetraspanin uroplakins and their co-evolution with associated proteins: implications for uroplakin structure and function.
A. García-España, Pei-Jung Chung, Xiao-Qian Zhao, A. Lee +4 more
2006Molecular Phylogenetics and Evolution57 citations
Semantic Scholar
Detection of circulating cancer cells expressing uroplakins and epidermal growth factor receptor in bladder cancer patients
I. Osman, M. Kang, A. Lee, Fang-Ming Deng +8 more
2004International Journal of Cancer53 citations
Semantic Scholar
Lack of major involvement of human uroplakin genes in vesicoureteral reflux: implications for disease heterogeneity.
Songshan Jiang, J. Gitlin, Fang-Ming Deng, Feng-Ying Liang +24 more
2004Kidney International51 citations Open access
Semantic Scholar
Differential expression of cell cycle regulators in phenotypic variants of transgenically induced bladder tumors: implications for tumor behavior.
A. García-España, E. Salazar, T. Sun, Xue-Ru Wu +1 more
2005Cancer Research49 citations
Semantic Scholar
Alterations in Bladder Function Associated With Urothelial Defects in Uroplakin II and IIIa Knockout Mice
T. Aboushwareb, Ge Zhou, Fang-Ming Deng, Chanda Turner +7 more
2009Neurourology and Urodynamics44 citations Open access
Semantic Scholar
Urothelial umbrella cells of human ureter are heterogeneous with respect to their uroplakin composition: different degrees of urothelial maturity in ureter and bladder?
I. Riedel, Feng-Xia Liang, Fang-Ming Deng, L. Tu +5 more
2005European Journal of Cell Biology44 citations
Semantic Scholar
Intron Evolution: Testing Hypotheses of Intron Evolution Using the Phylogenomics of Tetraspanins
A. García-España, Roso Marés, T. Sun, R. DeSalle
2009PLoS ONE40 citations Open access
Semantic Scholar
Allelic loss of p53 gene is associated with genesis and maintenance, but not invasion, of mouse carcinoma in situ of the bladder.
Jin Cheng, Hongying Huang, J. Pak, E. Shapiro +4 more
2003Cancer Research40 citations
Semantic Scholar
Involvement of Vps33a in the Fusion of Uroplakin-Degrading Multivesicular Bodies with Lysosomes
Xue-Mei Guo, L. Tu, I. Gumper, H. Plesken +9 more
2009Traffic : the International Journal of Intracellular Transport37 citations Open access
Semantic Scholar

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Hongying Huang×7

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R. Lavker — researcher profile on SciRah

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