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Allison E. Drew · SciRah

Researcher profile · Semantic Scholar

Allison E. Drew

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Allison E. Drew — researcher profile on SciRah

h-index: 7
Works: 23
Citations: 585

Most-cited papers

Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models
Elayne Chan-Penebre, Kelli A. Armstrong, Allison E. Drew, A. Grassian +11 more
2017Molecular Cancer Therapeutics150 citations Open access
Semantic Scholar
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma
Allison E. Drew, O. Moradei, S. Jacques, N. Rioux +20 more
2017Scientific Reports122 citations Open access
Semantic Scholar
Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltransferases: Identification of the First PRMT6 Tool Compound.
L. Mitchell, Allison E. Drew, S. Ribich, N. Rioux +14 more
2015ACS Medicinal Chemistry Letters121 citations Open access
Semantic Scholar
EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL
Dorothy Brach, Danielle Johnston-Blackwell, Allison E. Drew, T. Lingaraj +12 more
2017Molecular Cancer Therapeutics60 citations Open access
Semantic Scholar
The discovery and optimization of a novel class of potent, selective, and orally bioavailable anaplastic lymphoma kinase (ALK) inhibitors with potential utility for the treatment of cancer.
Richard T. Lewis, C. Bode, D. Choquette, Michele H Potashman +16 more
2012Journal of Medicinal Chemistry47 citations Open access
Semantic Scholar
Structural Insights into Ternary Complex Formation of Human CARM1 with Various Substrates.
P. Boriack-Sjodin, Lei Jin, S. Jacques, Allison E. Drew +6 more
2016ACS Chemical Biology45 citations
Semantic Scholar
Abstract 1795: Characterization of a novel series of potent, selective inhibitors of wild type and mutant/fusion anaplastic lymphoma kinase
K. Wilcoxen, R. Brake, D. Saffran, Y. Teffera +14 more
201210 citations
Semantic Scholar
Identification of a CARM1 Inhibitor with Potent In Vitro and In Vivo Activity in Preclinical Models of Multiple Myeloma
Allison E. Drew, O. Moradei, S. Jacques, N. Rioux +20 more
2017Scientific Reports7 citations Open access
Semantic Scholar
Comparison of 2 Cell-Based Phosphoprotein Assays to Support Screening and Development of an ALK Inhibitor
Allison E. Drew, Samer Al-Assaad, Violeta L. Yu, P. Andrews +5 more
2011Journal of biomolecular screening7 citations Open access
Semantic Scholar
Phosphatidylinositol-3 Kinase Delta (PI3Kδ) Inhibitor AMG 319 Is a Potent, Selective and Orally Bioavailable Small Molecule Inhibitor That Suppresses PI3K-Mediated Signaling and Viability in Neoplastic B Cells
A. Sinclair, D. Metz, Timothy D. Cushing, Liqin Liu +11 more
20116 citations
Semantic Scholar
Abstract 808: Opportunity for therapeutic expansion in mantle cell lymphoma: Tazemetostat combination synergy status in preclinical MCL models
T. Hood, Katherine Cosmopoulos, Allison E. Drew, Kelli A. Armstrong +3 more
2018Experimental and Molecular Therapeutics3 citations
Semantic Scholar
Abstract 5060: Activity of the EZH2 inhibitor tazemetostat as a monotherapy and in combination with multiple myeloma therapies in preclinical models
Allison E. Drew, V. Motwani, J. Campbell, Cu-Yue Tang +5 more
20173 citations
Semantic Scholar
Abstract C87: EZH2 inhibition leads to decreased proliferation in SMARCA4-deleted ovarian cancer cell lines
S. Knutson, Allison E. Drew, C. Plescia, R. Copeland +3 more
20153 citations
Semantic Scholar
Abstract 807: Mechanism of action of synergistic activity of EZH2 inhibition and IMiDs in preclinical multiple myeloma models
Allison E. Drew, V. Motwani, Lindsey W. Eichinger, Jesse J. Smith +1 more
2018Experimental and Molecular Therapeutics2 citations
Semantic Scholar
Abstract 2437: Crystal structures of CARM1 bound to sinefungin and diverse peptide substrates
A. Boriack-Sjodin, Lei Jin, S. Jacques, Allison E. Drew +3 more
20151 citations
Semantic Scholar
Abstract 2924: Aberrant SWI/SNF complexes lacking SMARCA2 or SMARCA4 differentially affect cell state and response to a novel SMARCA2/4 inhibitor
Lindsey W. Eichinger, Chloe Pantano, V. Motwani, Dorothy Brach +10 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 1768: Identification of a potent, orally-available SMARCA2/4 inhibitor with in vitro and in vivo activity in preclinical models of SMARCA4-mutant NSCLC
Allison E. Drew, S. Jacques, Lindsey W. Eichinger, Chloe Pantano +11 more
2020Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 3345: Selective killing of SMARCA2- and SMARCA4-deficient tumors by inhibition of EZH2:In vitroandin vivopreclinical models
Elayne Chan-Penebre, Kelli A. Armstrong, Allison E. Drew, A. Grassian +9 more
20170 citations
Semantic Scholar
Abstract 406: CRISPR pooled screening of hundreds of cancer cell lines identifies differential dependencies on epigenetic pathways and synthetic lethal relationships
A. Grassian, D. Harvey, Julian Fowler, Allison E. Drew +5 more
20170 citations
Semantic Scholar
Abstract B78: CRISPR pooled screening identifies differential dependencies on epigenetic pathways
A. Grassian, Julian Fowler, I. Feldman, T. Riera +7 more
20150 citations
Semantic Scholar
Abstract B85: EZH2 plays a critical role in B-cell maturation and in non-Hodgkin's lymphoma: Interplay between EZH2 function and B-cell activation
Danielle M. Johnston, Dorothy Brach, C. Plescia, Allison E. Drew +10 more
20150 citations
Semantic Scholar
Abstract 5376: Identification of the first small molecule PRMT6 inhibitor tool compound
Allison E. Drew, L. Mitchell, N. Rioux, K. Swinger +7 more
20150 citations
Semantic Scholar
Abstract 3142: Abnormal expression of the ALK protein in ovarian carcinoma is associated with low copy number amplification of the 2p23 locus
Patricia Merkel, B. Grubinska, Allison E. Drew, S. Szilvassy +6 more
20100 citations
Semantic Scholar

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Dorothy Brach — researcher profile on SciRah