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Emanuela Arena · SciRah

Researcher profile · Semantic Scholar

Emanuela Arena

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Emanuela Arena — researcher profile on SciRah

h-index: 15
Works: 25
Citations: 478

Most-cited papers

Role of the Nrf2/HO-1 axis in bronchopulmonary dysplasia and hyperoxic lung injuries.
E. Amata, V. Pittalà, A. Marrazzo, C. Parenti +4 more
2017Clinical science73 citations Open access
Semantic Scholar
Anti‐amnesic properties of (±)‐PPCC, a novel sigma receptor ligand, on cognitive dysfunction induced by selective cholinergic lesion in rats
V. Antonini, O. Prezzavento, Marino Coradazzi, A. Marrazzo +3 more
2009Journal of Neurochemistry47 citations
Semantic Scholar
(+)-and (-)-Phenazocine enantiomers: Evaluation of their dual opioid agonist/σ1 antagonist properties and antinociceptive effects.
O. Prezzavento, Emanuela Arena, C. Sánchez-Fernández, R. Turnaturi +6 more
2017European journal of medicinal chemistry43 citations Open access
Semantic Scholar
Antiangiogenic Effect of (±)-Haloperidol Metabolite II Valproate Ester [(±)-MRJF22] in Human Microvascular Retinal Endothelial Cells.
M. Olivieri, E. Amata, S. Vinciguerra, J. Fiorito +10 more
2016Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Synthesis and resolution of cis-(+/-)-methyl (1R,2S/1S,2R)-2-[(4-hydroxy-4-phenylpiperidin-1-yl)methyl]-1-(4-methylphenyl)cyclopropanecarboxylate [(+/-)-PPCC)]: new sigma receptor ligands with neuroprotective effect.
O. Prezzavento, Agata Campisi, C. Parenti, S. Ronsisvalle +7 more
2010Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?
Emanuela Arena, Maria Dichiara, G. Floresta, C. Parenti +4 more
2018Future Medicinal Chemistry27 citations
Semantic Scholar
Development of novel LP1-based analogues with enhanced delta opioid receptor profile.
L. Pasquinucci, R. Turnaturi, O. Prezzavento, Emanuela Arena +5 more
2017Bioorganic & Medicinal Chemistry22 citations Open access
Semantic Scholar
Design and synthesis of new bifunctional sigma-1 selective ligands with antioxidant activity.
Orazio Prezzavento, Emanuela Arena, C. Parenti, Lorella Pasquinucci +5 more
2013Journal of Medicinal Chemistry22 citations Open access
Semantic Scholar
Synthesis, in vitro and in vivo characterization of new benzoxazole and benzothiazole-based sigma receptor ligands.
G. Romeo, O. Prezzavento, Sebastiano Intagliata, V. Pittalà +9 more
2019European journal of medicinal chemistry21 citations Open access
Semantic Scholar
(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist.
L. Pasquinucci, R. Turnaturi, G. Calo, F. Pappalardo +7 more
2019European journal of medicinal chemistry20 citations Open access
Semantic Scholar
Synthesis and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-D-aspartate receptors.
R. Gitto, L. De Luca, S. Ferro, Maria R. Buemi +9 more
2011Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Nanoencapsulation strategies for the delivery of novel bifunctional antioxidant/σ1 selective ligands.
C. Carbone, Emanuela Arena, V. Pepe, O. Prezzavento +5 more
2017Colloids and Surfaces B: Biointerfaces19 citations
Semantic Scholar
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties.
E. Amata, A. Rescifina, O. Prezzavento, Emanuela Arena +7 more
2018Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.
E. Amata, Maria Dichiara, Emanuela Arena, V. Pittalà +7 more
2017Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
(+)-Pentazocine reduces oxidative stress and apoptosis in microglia following hypoxia/reoxygenation injury.
Kathrin Heiss, L. Vanella, P. Murabito, O. Prezzavento +8 more
2016Neuroscience Letters16 citations
Semantic Scholar
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation.
E. Amata, Maria Dichiara, Davide Gentile, A. Marrazzo +8 more
2020ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Development of New Benzylpiperazine Derivatives as σ1 Receptor Ligands with in Vivo Antinociceptive and Anti-Allodynic Effects
G. Romeo, Federica Bonanno, L. Wilson, Emanuela Arena +6 more
2021ACS Chemical Neuroscience11 citations Open access
Semantic Scholar
New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation.
Emanuela Arena, I. Cacciatore, L. S. Cerasa, H. Turkez +6 more
2016Bioorganic & Medicinal Chemistry9 citations Open access
Semantic Scholar
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists.
L. Pasquinucci, C. Parenti, M. C. Ruiz-Cantero, Z. Georgoussi +9 more
2020ACS Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Synthesis and Structure-Activity Relationships of (−)-cis-N-Normetazocine-Based LP1 Derivatives
L. Pasquinucci, C. Parenti, E. Amata, Z. Georgoussi +6 more
2018Pharmaceuticals7 citations Open access
Semantic Scholar
Corrigendum to "(+)-Pentazocine reduces oxidative stress and apoptosis in microglia following hypoxia/reoxygenation injury" [Neurosci. Lett. 626 (2016) 142-148].
Kathrin Heiss, L. Vanella, P. Murabito, O. Prezzavento +8 more
2023Neuroscience Letters1 citations
Semantic Scholar
Synthesis of Novel Benzylpiperazine Derivatives as Ligands for the σ1 Receptor
G. Romeo, L. Salerno, Federica Bonanno, V. Pittalà +6 more
20170 citations
Semantic Scholar
Development of Sigma Receptors Nitric Oxide Photodonor Ligands with Antiproliferative Activity
E. Amata, A. Marrazzo, Maria Dichiara, Emanuela Arena +6 more
20170 citations
Semantic Scholar
Tumor Targeting Sigma Receptor Ligands: Development of New Molecular Hybrids as Anticancer Therapeutics
Maria Dichiara, E. Amata, O. Prezzavento, Emanuela Arena +4 more
20170 citations
Semantic Scholar
HALOPERIDOL METABOLITE II VALPROATE ESTER: ANTIANGIOGENIC ACTIVITY IN HUMANMICROVASCULAR RETINAL ENDOTHELIAL CELLS
A. Marrazzo, E. Amata, M. Olivieri, O. Prezzavento +5 more
20160 citations
Semantic Scholar

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O. Prezzavento×23
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A. Marrazzo×18
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E. Amata×13
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C. Parenti×11
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R. Turnaturi×7

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