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Maria Dichiara · SciRah

Researcher profile · Semantic Scholar

Maria Dichiara

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Maria Dichiara — researcher profile on SciRah

h-index: 21
Works: 52
Citations: 2,085

Most-cited papers

Patterns of vascular cell adhesion molecule-1 and intercellular adhesion molecule-1 expression in rabbit and mouse atherosclerotic lesions and at sites predisposed to lesion formation.
Kaeko Iiyama, L. Hajra, M. Iiyama, Hong-Mei Li +3 more
1999Circulation Research685 citations Open access
Semantic Scholar
CREB binding protein is a required coactivator for Smad-dependent, transforming growth factor beta transcriptional responses in endothelial cells.
J. Topper, Maria Dichiara, Jonathan D. Brown, Amyj Williams +3 more
1998Proceedings of the National Academy of Sciences of the United States of America196 citations Open access
Semantic Scholar
MEKK-1, a Component of the Stress (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Pathway, Can Selectively Activate Smad2-mediated Transcriptional Activation in Endothelial Cells*
Jonathan D. Brown, Maria Dichiara, K. R. Anderson, M. Gimbrone +1 more
1999Journal of Biological Chemistry180 citations Open access
Semantic Scholar
Inhibition of E-Selectin Gene Expression by Transforming Growth Factor β in Endothelial Cells Involves Coactivator Integration of Smad and Nuclear Factor κB–Mediated Signals
Maria Dichiara, J. Kiely, M. Gimbrone, Mu-En Lee +2 more
2000Journal of Experimental Medicine116 citations Open access
Semantic Scholar
Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.
G. Floresta, V. Pistarà, E. Amata, Maria Dichiara +3 more
2017European journal of medicinal chemistry98 citations Open access
Semantic Scholar
Recent advances in drug discovery of phototherapeutic non-porphyrinic anticancer agents.
Maria Dichiara, O. Prezzavento, A. Marrazzo, V. Pittalà +3 more
2017European journal of medicinal chemistry76 citations
Semantic Scholar
Development of a Sigma‐2 Receptor affinity filter through a Monte Carlo based QSAR analysis
A. Rescifina, G. Floresta, A. Marrazzo, C. Parenti +4 more
2017European Journal of Pharmaceutical Sciences47 citations
Semantic Scholar
Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands.
G. Floresta, A. Rescifina, A. Marrazzo, Maria Dichiara +4 more
2017European journal of medicinal chemistry41 citations
Semantic Scholar
Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines.
V. Sorrenti, V. Pittalà, G. Romeo, E. Amata +12 more
2018European journal of medicinal chemistry40 citations Open access
Semantic Scholar
Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H3 and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties
K. Szczepańska, Sabina Podlewska, Maria Dichiara, Davide Gentile +15 more
2021ACS Chemical Neuroscience37 citations Open access
Semantic Scholar
Tuning Properties for Blood-Brain Barrier (BBB) Permeation: A Statistics-Based Analysis.
Maria Dichiara, B. Amata, R. Turnaturi, A. Marrazzo +1 more
2019ACS Chemical Neuroscience37 citations
Semantic Scholar
Heme Oxygenase Database (HemeOxDB) and QSAR Analysis of Isoform 1 Inhibitors
E. Amata, A. Marrazzo, Maria Dichiara, M. Modica +6 more
2017ChemMedChem36 citations
Semantic Scholar
Sigma-2 receptor ligands QSAR model dataset
A. Rescifina, G. Floresta, A. Marrazzo, C. Parenti +4 more
2017Data in Brief34 citations Open access
Semantic Scholar
Comprehensive data on a 2D-QSAR model for Heme Oxygenase isoform 1 inhibitors
E. Amata, A. Marrazzo, Maria Dichiara, M. Modica +6 more
2017Data in Brief34 citations Open access
Semantic Scholar
Inducible and selective transgene expression in murine vascular endothelium.
Peter I. Teng, Maria Dichiara, L. Kömüves, K. Abe +2 more
2002Physiological Genomics33 citations
Semantic Scholar
Identification of Potentially Potent Heme Oxygenase 1 Inhibitors through 3D‐QSAR Coupled to Scaffold‐Hopping Analysis
G. Floresta, E. Amata, Maria Dichiara, A. Marrazzo +5 more
2018ChemMedChem32 citations
Semantic Scholar
Repurposing of Human Kinase Inhibitors in Neglected Protozoan Diseases
Maria Dichiara, A. Marrazzo, O. Prezzavento, S. Collina +2 more
2017ChemMedChem30 citations Open access
Semantic Scholar
The egr‐1 promoter contains information for constitutive and inducible expression in transgenic mice
Jo C. Tsai, Li-Xin Liu, B. Cooley, Maria Dichiara +2 more
2000The FASEB Journal29 citations
Semantic Scholar
Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?
Emanuela Arena, Maria Dichiara, G. Floresta, C. Parenti +4 more
2018Future Medicinal Chemistry27 citations
Semantic Scholar
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents
A. N. Fallica, Carla Barbaraci, E. Amata, L. Pasquinucci +12 more
2021Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Dual Piperidine-Based Histamine H3 and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain
K. Szczepańska, T. Karcz, Maria Dichiara, S. Mogilski +21 more
2023Journal of Medicinal Chemistry21 citations Open access
Semantic Scholar
Dual Sigma-1 receptor antagonists and hydrogen sulfide-releasing compounds for pain treatment: Design, synthesis, and pharmacological evaluation.
Maria Dichiara, Antonia Artacho-Cordón, R. Turnaturi, Miriam Santos-Caballero +8 more
2022European journal of medicinal chemistry21 citations Open access
Semantic Scholar
Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5ʹ‐monophosphate glycosidase
G. Floresta, V. Pistarà, E. Amata, Maria Dichiara +5 more
2018Chemical Biology and Drug Design18 citations
Semantic Scholar
(+)-Methyl (1R,2S)-2-{[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]methyl}-1-phenylcyclopropanecarboxylate [(+)-MR200] Derivatives as Potent and Selective Sigma Receptor Ligands: Stereochemistry and Pharmacological Properties.
E. Amata, A. Rescifina, O. Prezzavento, Emanuela Arena +7 more
2018Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Novel Sigma Receptor Ligand-Nitric Oxide Photodonors: Molecular Hybrids for Double-Targeted Antiproliferative Effect.
E. Amata, Maria Dichiara, Emanuela Arena, V. Pittalà +7 more
2017Journal of Medicinal Chemistry16 citations Open access
Semantic Scholar
Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition
Maria Dichiara, Giuseppe Cosentino, G. Giordano, L. Pasquinucci +3 more
2023Expert Opinion on Drug Discovery15 citations
Semantic Scholar
Sigma Receptor Ligands Carrying a Nitric Oxide Donor Nitrate Moiety: Synthesis, In Silico, and Biological Evaluation.
E. Amata, Maria Dichiara, Davide Gentile, A. Marrazzo +8 more
2020ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Novel N-normetazocine Derivatives with Opioid Agonist/Sigma-1 Receptor Antagonist Profile as Potential Analgesics in Inflammatory Pain
R. Turnaturi, S. Chiechio, L. Pasquinucci, S. Spoto +7 more
2022Molecules13 citations Open access
Semantic Scholar
Haloperidol Metabolite II Valproate Ester (S)-(−)-MRJF22: Preliminary Studies as a Potential Multifunctional Agent Against Uveal Melanoma
Carla Barbaraci, Giovanni Giurdanella, C. Leotta, A. Longo +11 more
2021Journal of Medicinal Chemistry13 citations Open access
Semantic Scholar
Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands
G. Floresta, Maria Dichiara, Davide Gentile, O. Prezzavento +3 more
2019International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Combination of Heme Oxygenase-1 Inhibition and Sigma Receptor Modulation for Anticancer Activity
G. Romeo, Valeria Ciaffaglione, E. Amata, Maria Dichiara +8 more
2021Molecules12 citations Open access
Semantic Scholar
Exploiting the power of stereochemistry in drug action: 3-[(2S,6S,11S)-8-hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2H)-yl]-N-phenylpropanamide as potent sigma 1 receptor antagonist.
R. Turnaturi, L. Pasquinucci, S. Chiechio, M. Grasso +5 more
2020ACS Chemical Neuroscience10 citations
Semantic Scholar
Discovery of AD258 as a Sigma Receptor Ligand with Potent Antiallodynic Activity
Maria Dichiara, F. Ambrosio, Sang-Min Lee, M. C. Ruiz-Cantero +14 more
2023Journal of Medicinal Chemistry8 citations Open access
Semantic Scholar
Novel N-Substituted Benzomorphan-Based Compounds: From MOR-Agonist/DOR-Antagonist to Biased/Unbiased MOR Agonists.
L. Pasquinucci, C. Parenti, M. C. Ruiz-Cantero, Z. Georgoussi +9 more
2020ACS Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Exploring Structural Requirements for Sigma-1 Receptor Linear Ligands: Experimental and Computational Approaches
Lisa Lombardo, Salvatore Mirabile, R. Gitto, Giuseppe Cosentino +6 more
2024Journal of Chemical Information and Modeling7 citations
Semantic Scholar
Structure–Property Optimization of a Series of Imidazopyridines for Visceral Leishmaniasis
Maria Dichiara, Quillon J. Simpson, A. Quotadamo, Hitesh B. Jalani +16 more
2023ACS Infectious Diseases7 citations Open access
Semantic Scholar
Discovery of first novel sigma/HDACi dual-ligands with a potent in vitro antiproliferative activity.
Carla Barbaraci, V. di Giacomo, A. Maruca, Vincenzo Patamia +15 more
2023Bioorganic chemistry (Print)7 citations Open access
Semantic Scholar
Discovery, affinity maturation and multimerization of small molecule ligands against human tyrosinase and tyrosinase-related protein 1
M. Catalano, G. Bassi, Giulia Rotondi, Lyna Khettabi +5 more
2020RSC Medicinal Chemistry7 citations Open access
Semantic Scholar
Development of selective sigma-1 receptor ligands with antiallodynic activity: A focus on piperidine and piperazine scaffolds.
Giuseppe Cosentino, Maria Dichiara, F. Ambrosio, C. Leotta +12 more
2024European journal of medicinal chemistry6 citations Open access
Semantic Scholar
Discovery and computational studies of piperidine/piperazine-based compounds endowed with sigma receptor affinity
L. De Luca, Lisa Lombardo, Salvatore Mirabile, A. Marrazzo +4 more
2023RSC Medicinal Chemistry5 citations Open access
Semantic Scholar
Synthesis, Computational Insights, and Evaluation of Novel Sigma Receptors Ligands
Maria Dichiara, F. Ambrosio, Carla Barbaraci, R. González-Cano +7 more
2023ACS Chemical Neuroscience5 citations Open access
Semantic Scholar
Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.
Maria Dichiara, E. Amata, A. Rescifina, O. Prezzavento +4 more
2017Future Medicinal Chemistry5 citations
Semantic Scholar
Cytotoxicity Profiles and Neuroprotective Properties of the Novel Ifenprodil Analogues as Sigma Ligands
D. Zampieri, A. Calabretti, M. Romano, Sara Fortuna +5 more
2023Molecules4 citations Open access
Semantic Scholar
New Insights into the Opioid Analgesic Profile of cis-(−)-N-Normetazocine-derived Ligands
Giuliana Costanzo, R. Turnaturi, C. Parenti, S. Spoto +9 more
2023Molecules3 citations Open access
Semantic Scholar
Design, synthesis and biological evaluation of novel aminopropylcarboxamide derivatives as sigma ligands.
D. Zampieri, Sara Fortuna, M. Romano, E. Amata +5 more
2022Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Design, Synthesis, and Cytotoxic Assessment of New Haloperidol Analogues as Potential Anticancer Compounds Targeting Sigma Receptors
D. Zampieri, M. Romano, Sara Fortuna, E. Amata +4 more
2024Molecules2 citations Open access
Semantic Scholar
Design and Synthesis of Tetrahydropyrrolo[3,4‐c]Pyrazole Sigma‐1 Receptor Ligands
Giuseppe Cosentino, Maria Dichiara, Giuliana Costanzo, Alessandro Coco +4 more
2025ChemMedChem1 citations Open access
Semantic Scholar
Correction to “Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents”
A. N. Fallica, Carla Barbaraci, E. Amata, L. Pasquinucci +12 more
2022Journal of Medicinal Chemistry0 citations Open access
Semantic Scholar
H2S releasing molecules in pharmaceutical development.
Maria Dichiara, E. Amata
2022Future Medicinal Chemistry0 citations
Semantic Scholar
Synthesis of “no-light activated” Ciprofloxacin and Norfloxacin derivatives as potential biofilm dispersant agents
A. N. Fallica, Valeria Ciaffaglione, L. Carmen, Maria Dichiara +6 more
20190 citations
Semantic Scholar

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E. Amata×42
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E. Amata — researcher profile on SciRah
A. Marrazzo×40
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A. Marrazzo — researcher profile on SciRah
O. Prezzavento×20
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O. Prezzavento — researcher profile on SciRah
A. Rescifina×20
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×15

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L. Pasquinucci — researcher profile on SciRah

R. Turnaturi×12

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R. Turnaturi — researcher profile on SciRah

G. Floresta×10

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G. Floresta — researcher profile on SciRah

V. Pittalà×10

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V. Pittalà — researcher profile on SciRah

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C. Parenti — researcher profile on SciRah

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L. Salerno — researcher profile on SciRah

Carla Barbaraci×7

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Carla Barbaraci — researcher profile on SciRah

Giuseppe Cosentino×7

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Giuseppe Cosentino — researcher profile on SciRah