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B. Bernstein · SciRah

Researcher profile · Semantic Scholar

B. Bernstein

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B. Bernstein — researcher profile on SciRah

h-index: 109
Works: 253
Citations: 120K

Most-cited papers

An integrative model of cellular states, plasticity and genetics for glioblastoma
C. Neftel, J. Laffy, M. Filbin, T. Hara +54 more
2019Cell2,441 citations Open access
Semantic Scholar
Single-cell transcriptomic analysis of primary and metastatic tumor ecosystems in head and neck cancer
Sidharth V. Puram, I. Tirosh, Anuraag S. Parikh, Anoop P. Patel +15 more
2017Cell2,292 citations Open access
Semantic Scholar
Expanded encyclopaedias of DNA elements in the human and mouse genomes
Jill E. Moore, M. Purcaro, Henry E. Pratt, C. Epstein +59 more
2020Nature2,079 citations Open access
Semantic Scholar
Cohesin loss eliminates all loop domains
Suhas S. P. Rao, Su-Chen Huang, B. G. St Hilaire, Jesse M. Engreitz +18 more
2017Cell1,697 citations Open access
Semantic Scholar
Epigenetic plasticity and the hallmarks of cancer
William A. Flavahan, Elizabeth Gaskell, B. Bernstein
2017Science1,240 citations Open access
Semantic Scholar
Single-cell RNA-seq supports a developmental hierarchy in human oligodendroglioma
I. Tirosh, Andrew S. Venteicher, Christine Hebert, Leah E. Escalante +34 more
2016Nature1,087 citations Open access
Semantic Scholar
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
H. Finucane, Yakir A. Reshef, V. Anttila, Kamil Slowikowski +17 more
2017Nature Genetics1,030 citations Open access
Semantic Scholar
Single-cell RNA-seq reveals AML hierarchies relevant to disease progression and immunity
P. van Galen, V. Hovestadt, M. Wadsworth, T. Hughes +15 more
2019Cell1,027 citations Open access
Semantic Scholar
Decoupling genetics, lineages, and microenvironment in IDH-mutant gliomas by single-cell RNA-seq
Andrew S. Venteicher, I. Tirosh, Christine Hebert, K. Yizhak +30 more
2017Science910 citations Open access
Semantic Scholar
Genome-wide Programmable Transcriptional Memory by CRISPR-based Epigenome Editing
J. K. Nuñez, Jin Chen, Greg C. Pommier, J. Cogan +16 more
2021Cell661 citations Open access
Semantic Scholar
Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq
M. Filbin, I. Tirosh, V. Hovestadt, McKenzie L Shaw +45 more
2018Science595 citations Open access
Semantic Scholar
Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq
Mihriban Karaayvaz, Simona Cristea, Shawn M. Gillespie, Anoop P. Patel +6 more
2018Nature Communications437 citations Open access
Semantic Scholar
A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression
Rajat M. Gupta, J. Hadaya, Aditi Trehan, S. Zekavat +17 more
2017Cell421 citations Open access
Semantic Scholar
Resolving medulloblastoma cellular architecture by single-cell genomics
V. Hovestadt, Kyle S. Smith, Laure Bihannic, M. Filbin +47 more
2019Nature345 citations Open access
Semantic Scholar
Epigenetic Silencing by SETDB1 Suppresses Tumor Intrinsic Immunogenicity
G. Griffin, Jingyi Wu, Arvin Iracheta-Vellve, J. C. Patti +25 more
2021Nature328 citations Open access
Semantic Scholar
Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma
S. McBrayer, Jared R. Mayers, G. Dinatale, Diana D. Shi +23 more
2018Cell319 citations Open access
Semantic Scholar
Abstract LB-096: SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation
Xiao-Feng Wang, Ryan S. Lee, B. Alver, Jeffrey R. Haswell +5 more
2017299 citations
Semantic Scholar
Test performance evaluation of SARS-CoV-2 serological assays
J. Whitman, J. Hiatt, Cody T. Mowery, B. Shy +68 more
2020medRxiv276 citations Open access
Semantic Scholar
An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma
Y. Drier, M. J. Cotton, K. Williamson, Shawn M. Gillespie +16 more
2016Nature Genetics267 citations Open access
Semantic Scholar
Orthologous CRISPR-Cas9 enzymes for Combinatorial Genetic Screens
Fadi J. Najm, Christine Strand, K. Donovan, M. Hegde +11 more
2017Nature Biotechnology259 citations Open access
Semantic Scholar
Widespread RNA binding by chromatin-associated proteins
David G. Hendrickson, David R. Kelley, D. Tenen, B. Bernstein +1 more
2016Genome Biology242 citations Open access
Semantic Scholar
Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in the aging and Alzheimer human brain
Hans-Ulrich Klein, C. McCabe, Elizabeta Gjoneska, S. Sullivan +13 more
2018Nature Neuroscience240 citations Open access
Semantic Scholar
Altered chromosomal topology drives oncogenic programs in SDH-deficient GISTs
William A. Flavahan, Y. Drier, Sarah E. Johnstone, Matthew L. Hemming +11 more
2019Nature231 citations Open access
Semantic Scholar
Test performance evaluation of SARS-CoV-2 serological assays
J. Whitman, J. Hiatt, Cody T. Mowery, B. Shy +68 more
2020Nature Biotechnology223 citations Open access
Semantic Scholar
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
Tyler E. Miller, Brian B Liau, Lisa C. Wallace, A. Morton +20 more
2017Nature190 citations Open access
Semantic Scholar
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
Sarah E. Johnstone, Alejandro Reyes, Yifeng Qi, C. Adriaens +17 more
2020Cell187 citations Open access
Semantic Scholar
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
M. Kleppe, R. Koche, L. Zou, P. van Galen +20 more
2017Cancer Cell170 citations Open access
Semantic Scholar
Systematic dissection of genomic features determining transcription factor binding and enhancer function
Sharon R. Grossman, Xiao-Lan Zhang, Li Wang, Jesse M. Engreitz +8 more
2017Proceedings of the National Academy of Sciences of the United States of America170 citations Open access
Semantic Scholar
Perspectives on ENCODE
Michael P. Snyder, T. Gingeras, Jill E. Moore, Z. Weng +17 more
2020Nature166 citations Open access
Semantic Scholar
Enhancer signatures stratify and predict outcomes of non-functional pancreatic neuroendocrine tumors
P. Cejas, Y. Drier, K. Dreijerink, L. Brosens +23 more
2019Nature Medicine157 citations Open access
Semantic Scholar
Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG.
Jamie N. Anastas, Barry M. Zee, Jay H. Kalin, Mirhee Kim +17 more
2019Cancer Cell156 citations Open access
Semantic Scholar
Single-cell and single-molecule epigenomics to uncover genome regulation at unprecedented resolution
E. Shema, B. Bernstein, Jason D. Buenrostro
2018Nature Genetics156 citations
Semantic Scholar
Single-Molecule Decoding of Combinatorially-Modified Nucleosomes
E. Shema, Daniel L. Jones, N. Shoresh, Laura Donohue +2 more
2016Science137 citations Open access
Semantic Scholar
Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms
M. Kleppe, Richard P. Koche, L. Zou, P. van Galen +20 more
2018Cancer Cell136 citations Open access
Semantic Scholar
Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro
Michael-John Dolan, Martine Therrien, Saša Jereb, Tushar Kamath +20 more
2023Nature Immunology134 citations Open access
Semantic Scholar
Clinical sensitivity and interpretation of PCR and serological COVID‐19 diagnostics for patients presenting to the hospital
T. Miller, Wilfredo F. Garcia Beltran, Adam Z. Bard, T. Gogakos +32 more
2020medRxiv133 citations Open access
Semantic Scholar
Mitochondrial variant enrichment from high-throughput single-cell RNA-seq resolves clonal populations
T. Miller, C. Lareau, Julia A. Verga, Erica A. K. DePasquale +14 more
2022Nature Biotechnology117 citations Open access
Semantic Scholar
Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance
C. Eyler, Hironori Matsunaga, V. Hovestadt, Samantha J. Vantine +2 more
2020Genome Biology92 citations Open access
Semantic Scholar
Epigenetic clocks, aging, and cancer
Sarah E. Johnstone, V. Gladyshev, M. Aryee, B. Bernstein
2022Science88 citations
Semantic Scholar
Epigenome editing strategies for the functional annotation of CTCF insulators
Daniel R. Tarjan, William A. Flavahan, B. Bernstein
2019Nature Communications80 citations Open access
Semantic Scholar
Single cell RNA-seq reveals developmental plasticity with coexisting oncogenic and immune evasion programs in ETP-ALL.
P. Anand, A. Guillaumet-Adkins, V. Dimitrova, Huiyoung Yun +23 more
2020Blood77 citations Open access
Semantic Scholar
Epithelial-to-mesenchymal transition antagonizes response to targeted therapies in lung cancer by suppressing BIM
Kyung-A Song, M. Niederst, Timothy L. Lochmann, A. Hata +26 more
2017Clinical Cancer Research77 citations Open access
Semantic Scholar
The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
J. Rozowsky, Jia-Hao Gao, Beatrice Borsari, Yucheng T. Yang +99 more
2022bioRxiv76 citations Open access
Semantic Scholar
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
A. Pastore, Federico Gaiti, Sydney X. Lu, Ryan Brand +19 more
2019Nature Communications76 citations Open access
Semantic Scholar
A Unique B-cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B-cell Lymphomas
Russell J. H. Ryan, Jelena Petrovic, D. Rausch, Yeqiao Zhou +16 more
2017Cell Reports73 citations Open access
Semantic Scholar
High Seroprevalence of Anti-SARS-CoV-2 Antibodies in Chelsea, Massachusetts
V. Naranbhai, Christina C. Chang, Wilfredo F. Garcia Beltran, T. Miller +19 more
2020Journal of Infectious Diseases71 citations Open access
Semantic Scholar
Modeling epigenetic lesions that cause gliomas
G. Rahme, Nauman Javed, Kaitlyn L. Puorro, Shouhui Xin +3 more
2023Cell67 citations Open access
Semantic Scholar
Immunohistochemical quantification of partial-EMT in oral cavity squamous cell carcinoma primary tumors is associated with nodal metastasis
Anuraag S. Parikh, Sidharth V. Puram, W. Faquin, J. Richmon +6 more
2019Oral Oncology59 citations Open access
Semantic Scholar
Ultraviolet radiation shapes dendritic cell leukaemia transformation in the skin
G. Griffin, Christopher A. G. Booth, Katsuhiro Togami, Sun Sook Chung +12 more
2023Nature58 citations Open access
Semantic Scholar
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.
Qi Xie, Qiulian Wu, Leo J Y Kim, Tyler E. Miller +12 more
2016Journal of Clinical Investigation58 citations Open access
Semantic Scholar

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