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D. Tenen · SciRah

Researcher profile · Semantic Scholar

D. Tenen

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D. Tenen — researcher profile on SciRah

h-index: 113
Works: 526
Citations: 45K

Most-cited papers

Patients with cancer appear more vulnerable to SARS-COV-2: a multi-center study during the COVID-19 outbreak
Mengyuan Dai, Dianbo Liu, Miao Liu, Fu-Xiang Zhou +34 more
2020Cancer Discovery1,435 citations Open access
Semantic Scholar
Single cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species
R. Zilionis, Camilla Engblom, C. Pfirschke, Virginia Savova +14 more
2019Immunity1,357 citations Open access
Semantic Scholar
EGFR signaling pathway as therapeutic target in human cancers.
E. Levantini, Giorgia Maroni, M. Del Re, D. Tenen
2022Seminars in Cancer Biology335 citations Open access
Semantic Scholar
APOE4 impairs the microglial response in Alzheimer’s disease by inducing TGFβ-mediated checkpoints
Zhuoran Yin, Neta Rosenzweig, Kilian L. Kleemann, Xiaoming Zhang +39 more
2023Nature Immunology176 citations Open access
Semantic Scholar
NanoVar: accurate characterization of patients’ genomic structural variants using low-depth nanopore sequencing
C. Tham, Roberto Tirado-Magallanes, Yu-Fen Goh, M. Fullwood +7 more
2019Genome Biology106 citations Open access
Semantic Scholar
Hlf marks the developmental pathway for hematopoietic stem cells but not for erythro-myeloid progenitors
T. Yokomizo, Naoki Watanabe, Terumasa Umemoto, J. Matsuo +15 more
2019Journal of Experimental Medicine74 citations Open access
Semantic Scholar
ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function
Qi-Ling Zhou, Miao Yu, Roberto Tirado-Magallanes, Bin Li +11 more
2021Nature Communications70 citations Open access
Semantic Scholar
Metabolic alterations and vulnerabilities in hepatocellular carcinoma
D. Tenen, L. Chai, Justin L. Tan
2020Gastroenterology Report66 citations Open access
Semantic Scholar
The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia.
S. Tan, Wei Zhong Leong, P. C. T. Ngoc, Tze-King Tan +8 more
2019Blood61 citations Open access
Semantic Scholar
New High-throughput Screen Identifies Compounds That Reduce Viability Specifically In Liver Cancer Cells That Express High Levels of SALL4 by Inhibiting Oxidative Phosphorylation
Justin L. Tan, Feng Li, J. Yeo, Kol Jia Yong +33 more
2019Gastroenterology56 citations Open access
Semantic Scholar
Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice
Chenxi Qiu, Onder Albayram, A. Kondo, Bin Wang +21 more
2021Science Translational Medicine55 citations Open access
Semantic Scholar
Chronic interleukin-1 exposure triggers selection for Cebpa-knockout multipotent hematopoietic progenitors
K. Higa, Andrew E. Goodspeed, James S. Chavez, M. De Dominici +6 more
2021Journal of Experimental Medicine51 citations Open access
Semantic Scholar
Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression
N. Kong, M. Bassal, Hong-Kee Tan, Jesse V. Kurland +13 more
2020bioRxiv51 citations Open access
Semantic Scholar
β-catenin-TCF/LEF signaling promotes steady-state and emergency granulopoiesis via G-CSF receptor upregulation.
P. Daněk, M. Kardosova, L. Janečková, Elena Karkoulia +13 more
2019Blood51 citations Open access
Semantic Scholar
CAV1 - GLUT3 signaling is important for cellular energy and can be targeted by Atorvastatin in Non-Small Cell Lung Cancer
Azhar Ali, E. Levantini, C. Fhu, J. Teo +6 more
2019Theranostics50 citations Open access
Semantic Scholar
CARM1 Is Essential for Myeloid Leukemogenesis but Dispensable for Normal Hematopoiesis.
Sarah M. Greenblatt, Na Man, Pierre-Jacques Hamard, T. Asai +21 more
2019Cancer Cell50 citations Open access
Semantic Scholar
Metabolic alterations mediated by STAT3 promotes drug persistence in CML
Sweta B. Patel, T. Nemkov, D. Stefanoni, G. Benavides +20 more
2021Leukemia49 citations Open access
Semantic Scholar
Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
Giacomo Canesin, A. Di Ruscio, Mailin Li, S. Ummarino +15 more
2020Cell Reports48 citations Open access
Semantic Scholar
Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy
Yao-Chung Liu, J. Kwon, E. Fabiani, Zhijian Xiao +23 more
2022New England Journal of Medicine44 citations Open access
Semantic Scholar
E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates
Anaïs Wanet, M. Bassal, Sweta B. Patel, Francisco Marchi +17 more
2021Science immunology41 citations Open access
Semantic Scholar
Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA
Wendi Sun, Lingyun Dai, Han Yu, Brenda Puspita +9 more
2019Redox Biology41 citations Open access
Semantic Scholar
PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development
Xin-Hui Zhao, Boris A. Bartholdy, Yukiya Yamamoto, E. Evans +10 more
2022Communications Biology40 citations Open access
Semantic Scholar
SALL4: An Intriguing Therapeutic Target in Cancer Treatment
S. Moein, D. Tenen, G. Amabile, L. Chai
2022Cells32 citations Open access
Semantic Scholar
Pseudogene-mediated DNA demethylation leads to oncogene activation
J. Kwon, Yanjing V. Liu, C. Gao, M. Bassal +10 more
2020bioRxiv26 citations Open access
Semantic Scholar
Lessons learned from early compassionate use of convalescent plasma on critically ill patients with Covid‐19
Miao Liu, Zhen Chen, Mengyuan Dai, Junhui Yang +13 more
2020Transfusion23 citations Open access
Semantic Scholar
Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML.
B. Trinh, S. Ummarino, Yan-Zhou Zhang, A. Ebralidze +24 more
2021Blood22 citations Open access
Semantic Scholar
Long noncoding RNA–mediated activation of PROTOR1/PRR5-AKT signaling shunt downstream of PI3K in triple-negative breast cancer
Zhen-Bo Tu, Yi Hu, Devesh Raizada, M. Bassal +2 more
2022Proceedings of the National Academy of Sciences of the United States of America21 citations Open access
Semantic Scholar
Germline mutations in mitochondrial complex I reveal genetic and targetable vulnerability in IDH1-mutant acute myeloid leukaemia
M. Bassal, S. Samaraweera, Kelly Lim, Brooks A. Benard +23 more
2022Nature Communications21 citations Open access
Semantic Scholar
Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer
Giorgia Maroni, M. Bassal, Indira S. Krishnan, C. Fhu +36 more
2021Communications Biology21 citations Open access
Semantic Scholar
Targeting an inducible SALL4-mediated cancer vulnerability with sequential therapy
Jun-Yu Yang, Chong Gao, Miao Liu, Yao-Chung Liu +19 more
2021Cancer Research21 citations Open access
Semantic Scholar
Repurposing RNA sequencing for discovery of RNA modifications in clinical cohorts
K. Tan, Ling-Wen Ding, Chan-shuo Wu, D. Tenen +1 more
2021Science Advances21 citations Open access
Semantic Scholar
Targeting microtubules sensitizes drug resistant lung cancer cells to lysosomal pathway inhibitors
T. Chin, Gandhi T K Boopathy, E. P. Man, J. Clohessy +13 more
2020Theranostics21 citations Open access
Semantic Scholar
C/EBPβ is a critical mediator of IFN-α-induced exhaustion of chronic myeloid leukemia stem cells.
A. Yokota, H. Hirai, R. Sato, Hiroko Adachi +10 more
2019Blood Advances21 citations Open access
Semantic Scholar
Core binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.
Ming-Rui Guo, M. Chan, Qi-Ling Zhou, Omer An +25 more
2023Blood20 citations
Semantic Scholar
A modified CUT&RUN protocol and analysis pipeline to identify transcription factor binding sites in human cell lines
N. Kong, L. Chai, D. Tenen, M. Bassal
2021STAR Protocols18 citations Open access
Semantic Scholar
Emerging therapies for inv(16) AML.
Sridevi Surapally, D. Tenen, J. Pulikkan
2021Blood17 citations Open access
Semantic Scholar
Extracellular vesicle surface display enhances the therapeutic efficacy and safety profile of cancer immunotherapy
M. Jayasinghe, Yock Sin Lay, Dawn Xiao Tian Liu, C. Lee +11 more
2024Molecular Therapy15 citations Open access
Semantic Scholar
DNMT3B shapes the mCA landscape and regulates mCG for promoter bivalency in human embryonic stem cells
Hong-Kee Tan, Chan-shuo Wu, Jia Li, Zi-Hui Tan +5 more
2019Nucleic Acids Research15 citations Open access
Semantic Scholar
SALL4 and microRNA: The Role of Let-7
J. Liu, Madeline A. Sauer, Shaza G Hussein, Jun-Yu Yang +2 more
2021Genes12 citations Open access
Semantic Scholar
Diverse functions of long non-coding RNAs in AML: emerging roles in pathophysiology, prognosis, and treatment resistance
Srishti Mishra, J. Liu, Li Chai, D. Tenen
2021Current opinion in hematology12 citations Open access
Semantic Scholar
Core binding factor leukemia hijacks T-cell prone PU.1 antisense promoter.
E. van der Kouwe, G. Heller, A. Czibere, J. Pulikkan +29 more
2021Blood11 citations Open access
Semantic Scholar
Non-coding RNA LEVER sequestration of PRC2 can mediate long range gene regulation
Wei-Wen Teo, Xinang Cao, Chan-shuo Wu, Hong-Kee Tan +8 more
2022Communications Biology10 citations Open access
Semantic Scholar
Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines
Hiroki Hosoi, Akiko Niibori-Nambu, G. Nah, A. G. Bahirvani +7 more
2021Gene10 citations Open access
Semantic Scholar
Tumor Microenvironment Landscapes Supporting EGFR-mutant NSCLC Are Modulated at the Single-cell Interaction Level by Unesbulin Treatment
Giorgia Maroni, Indira S. Krishnan, Roberta Alfieri, Valerie A Maymi +18 more
2024Cancer Research Communications9 citations Open access
Semantic Scholar
Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia
Jonathan D. Lee, João A. Paulo, Ryan R. Posey, V. Mugoni +8 more
2021Nature Methods9 citations Open access
Semantic Scholar
circASXL1-1 regulates BAP1 deubiquitinase activity in leukemia
S. Jadhav, Kumari Nishi, Larry Ng, P. Tan +14 more
2019Haematologica9 citations Open access
Semantic Scholar
C/EBPγ is dispensable for steady-state and emergency granulopoiesis
M. Kardosova, P. Zjablovskaja, P. Daněk, P. Angelisová +6 more
2018Haematologica9 citations Open access
Semantic Scholar
Improved hematopoietic stem cell transplantation upon inhibition of natural killer cell-derived interferon-gamma
Lorena Lobo de Figueiredo-Pontes, M. Adamcová, Srdjan Grusanovic, M. Kuzmina +11 more
2021Stem Cell Reports8 citations Open access
Semantic Scholar
Super-silencer perturbation by EZH2 and REST inhibition leads to large loss of chromatin interactions and reduction in cancer growth
Ying Zhang, Kaijing Chen, S. Tang, Yi-Chao Cai +16 more
2024Nature Structural & Molecular Biology7 citations Open access
Semantic Scholar
Three-dimensional Genome Organization Maps in Normal Haematopoietic Stem Cells and Acute Myeloid Leukemia
Benny Wang, Lingshi Kong, D. Babu, R. Choudhary +16 more
2020bioRxiv5 citations Open access
Semantic Scholar

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