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A. Pastore · SciRah

Researcher profile · Semantic Scholar

A. Pastore

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A. Pastore — researcher profile on SciRah

h-index: 30
Works: 70
Citations: 8,730

Most-cited papers

Comprehensive molecular portraits of invasive lobular breast cancer
G. Ciriello, M. Gatza, Andrew H. Beck, M. Wilkerson +137 more
2015Cell1,737 citations Open access
Semantic Scholar
Integrated genomic and molecular characterization of cervical cancer
R. Burk, Zi-Gui Chen, C. Saller, Katherine Tarvin +297 more
2017Nature1,275 citations Open access
Semantic Scholar
COMPREHENSIVE AND INTEGRATED GENOMIC CHARACTERIZATION OF ADULT SOFT TISSUE SARCOMAS
A. Abeshouse, C. Adebamowo, S. Adebamowo, R. Akbani +260 more
2017Cell950 citations Open access
Semantic Scholar
Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry.
A. Pastore, V. Jurinovic, R. Kridel, E. Hoster +31 more
2015The Lancet Oncology681 citations
Semantic Scholar
Ibrutinib Unmasks Critical Role of Bruton Tyrosine Kinase in Primary CNS Lymphoma
C. Grommes, A. Pastore, N. Palaskas, Sarah S Tang +38 more
2017Cancer Discovery350 citations Open access
Semantic Scholar
Lactose drives Enterococcus expansion to promote graft-versus-host disease
C. Stein-Thoeringer, K. Nichols, A. Lazrak, M. Docampo +49 more
2019Science306 citations Open access
Semantic Scholar
Targeting an RNA-binding Protein Network in Acute Myeloid Leukemia
Eric Wang, Sydney X. Lu, A. Pastore, Xufeng Chen +17 more
2019Cancer Cell293 citations Open access
Semantic Scholar
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types
Diego Chowell, Seong-Keun Yoo, C. Valero, A. Pastore +30 more
2021Nature Biotechnology240 citations Open access
Semantic Scholar
Genotyping of Transcriptomes links somatic mutations and cell identity
Anna S. Nam, Kyu-Tae Kim, R. Chaligné, Franco Izzo +20 more
2019Nature236 citations Open access
Semantic Scholar
Epigenetic evolution and lineage histories of chronic lymphocytic leukemia
Federico Gaiti, R. Chaligné, H. Gu, Ryan Brand +22 more
2019Nature235 citations Open access
Semantic Scholar
Modulation of splicing catalysis for therapeutic targeting of leukemias with spliceosomal mutations
S. Lee, H. Dvinge, Eunhee Kim, Hana Cho +18 more
2016Nature Medicine229 citations Open access
Semantic Scholar
Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations
S. Lee, Khrystyna North, Eunhee Kim, E. Jang +23 more
2018Cancer Cell206 citations Open access
Semantic Scholar
Coordinated Alterations in RNA Splicing and Epigenetic Regulation Drive Leukemogenesis
A. Yoshimi, Kuan-Ting Lin, D. Wiseman, M. Rahman +25 more
2019Nature203 citations Open access
Semantic Scholar
Activating mutations in CSF-1R and additional receptor tyrosine kinases in histiocytic neoplasms
B. Durham, Estibaliz Lopez Rodrigo, J. Picarsic, D. Abramson +32 more
2019Nature Medicine198 citations Open access
Semantic Scholar
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease
E. Mass, Christian E. Jacome-Galarza, T. Blank, T. Lazarov +9 more
2017Nature195 citations Open access
Semantic Scholar
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer
Luisa F. Escobar-Hoyos, A. Penson, Ramaraj Kannan, Hana Cho +40 more
2020Cancer Cell148 citations Open access
Semantic Scholar
Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
R. Nagase, D. Inoue, A. Pastore, Takeshi Fujino +16 more
2018Journal of Experimental Medicine136 citations Open access
Semantic Scholar
KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function
Kinisha Gala, Qing Li, A. Sinha, P. Razavi +10 more
2018Oncogene120 citations Open access
Semantic Scholar
3’UTR mediated regulation of the cyclin D1 proto-oncogene
Anagha Deshpande, A. Pastore, A. Deshpande, Y. Zimmermann +5 more
2009Cell Cycle95 citations Open access
Semantic Scholar
The Role of Therapeutic Leukapheresis in Hyperleukocytotic AML
F. Pastore, A. Pastore, G. Wittmann, W. Hiddemann +1 more
2014PLoS ONE81 citations Open access
Semantic Scholar
Altered nuclear export signal recognition as a driver of oncogenesis
Justin Taylor, M. Sendino, A. Gorelick, A. Pastore +23 more
2019Cancer Discovery80 citations Open access
Semantic Scholar
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
A. Pastore, Federico Gaiti, Sydney X. Lu, Ryan Brand +19 more
2019Nature Communications76 citations Open access
Semantic Scholar
Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma.
D. Bararia, J. Hildebrand, S. Stolz, S. Haebe +34 more
2020Cell Reports70 citations Open access
Semantic Scholar
Sequence-dependent synergy of the proteasome inhibitor bortezomib and cytarabine in mantle cell lymphoma
O. Weigert, A. Pastore, M. Rieken, N. Lang +2 more
2007Leukemia69 citations Open access
Semantic Scholar
PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN
F. Pastore, Neha Bhagwat, A. Pastore, Aliaksandra Radzisheuskaya +22 more
2020Cancer Discovery68 citations Open access
Semantic Scholar
Duodenal-type and nodal follicular lymphomas differ by their immune microenvironment rather than their mutation profiles.
J. Hellmuth, A. Louissaint, M. Szczepanowski, S. Haebe +16 more
2018Blood65 citations
Semantic Scholar
ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia
J. Micol, A. Pastore, D. Inoue, Nicolas Duployez +13 more
2017Nature Communications63 citations Open access
Semantic Scholar
Complete Responses in Relapsed/Refractory Acute Myeloid Leukemia (AML) Patients on a Weekly Dosing Schedule of Vibecotamab (XmAb14045), a CD123 x CD3 T Cell-Engaging Bispecific Antibody; Initial Results of a Phase 1 Study
F. Ravandi, A. Bashey, W. Stock, J. Foran +9 more
2020Blood58 citations Open access
Semantic Scholar
Allelic loss on chromosomes 2q21 and 19p 13.2 in oxyphilic thyroid tumors
K. Stankov, A. Pastore, L. Toschi, J. Mckay +8 more
2004International Journal of Cancer34 citations Open access
Semantic Scholar
The proteasome inhibitor bortezomib targets cell cycle and apoptosis and acts synergistically in a sequence-dependent way with chemotherapeutic agents in mantle cell lymphoma
G. Hutter, M. Rieken, A. Pastore, O. Weigert +4 more
2012Annals of Hematology32 citations
Semantic Scholar
Single-Agent Ibrutinib in Recurrent/Refractory Central Nervous System Lymphoma
C. Grommes, A. Pastore, I. Gavrilovic, T. Kaley +7 more
201626 citations
Semantic Scholar
Combination of hyperthermia and bortezomib results in additive killing in mantle cell lymphoma cells
V. Milani, Monika Lorenz, M. Weinkauf, M. Rieken +3 more
2009International Journal of Hyperthermia26 citations Open access
Semantic Scholar
Impact of age on clinical risk scores in follicular lymphoma.
S. Alig, V. Jurinovic, A. Pastore, S. Haebe +7 more
2019Blood Advances21 citations Open access
Semantic Scholar
2‐D PAGE‐based comparison of proteasome inhibitor bortezomib in sensitive and resistant mantle cell lymphoma
M. Weinkauf, Y. Zimmermann, E. Hartmann, A. Rosenwald +5 more
2009Electrophoresis21 citations
Semantic Scholar
The microRNA miR-196b acts as a tumor suppressor in Cdx2-driven acute myeloid leukemia
Vijay P. S. Rawat, Maria Götze, A. Rasalkar, Naidu M. Vegi +9 more
2020Haematologica16 citations Open access
Semantic Scholar
Radioimmunotherapy in relapsed/refractory mantle cell lymphoma patients: final results of a European MCL Network Phase II Trial
Simone Ferrero, A. Pastore, Christian Scholz, R. Forstpointner +11 more
2013Leukemia15 citations
Semantic Scholar
Impact of age on genetics and treatment efficacy in follicular lymphoma
S. Alig, V. Jurinovic, A. Pastore, D. Bararia +12 more
2018Haematologica13 citations Open access
Semantic Scholar
Identification of single nucleotide variations in the coding and regulatory regions of the myelin-associated glycoprotein gene and study of their association with multiple sclerosis.
S. D'Alfonso, M. Mellai, M. Giordano, A. Pastore +9 more
2002Journal of Neuroimmunology13 citations
Semantic Scholar
Molecular profiling of patients with cytogenetically normal acute myeloid leukemia and hyperleukocytosis
F. Pastore, A. Pastore, M. Rothenberg-Thurley, K. Metzeler +11 more
2022Cancer12 citations Open access
Semantic Scholar
CD33 splice site genotype was not associated with outcomes of patients receiving the anti-CD33 drug conjugate SGN-CD33A
M. Stanchina, A. Pastore, S. Devlin, C. Famulare +2 more
2019Journal of Hematology & Oncology11 citations Open access
Semantic Scholar
Corrigendum: Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins
S. Lee, H. Dvinge, Eunhee Kim, Hana Cho +18 more
2016Nature Medicine10 citations Open access
Semantic Scholar
Activating Mutations in CSF1R and Additional Receptor Tyrosine Kinases in Sporadic and Familial Histiocytic Neoplasms
B. Durham, Estibaliz Lopez-Rodrigo, D. Abramson, J. Picarsic +13 more
2018Blood8 citations Open access
Semantic Scholar
High throughput droplet single-cell Genotyping of Transcriptomes (GoT) reveals the cell identity dependency of the impact of somatic mutations
Anna S. Nam, Kyu-Tae Kim, R. Chaligné, Franco Izzo +15 more
2018bioRxiv8 citations Open access
Semantic Scholar
Inhibition of Protein Kinase C beta by Enzastaurin (LY 317615) Induces Alterations of Key Regulators of Cell Cycle and Apoptosis in Mantle Cell Lymphoma and Synergizes with Chemotherapeutic Agents in a Sequence Dependent Manner.
M. Rieken, O. Weigert, A. Pastore, G. Hutter +4 more
20058 citations
Semantic Scholar
STAT6 Is Recurrently and Significantly Mutated in Follicular Lymphoma and Enhances the IL-4 Induced Expression of Membrane-Bound and Soluble CD23
Michael W. Bösl, Elisa Osterode, D. Bararia, A. Pastore +7 more
20154 citations
Semantic Scholar
ASXL2 Is a Novel Mediator of RUNX1-ETO Transcriptional Function and Collaborates with RUNX1-ETO to Promote Leukemogenesis
J. Micol, Nicolas Duployez, A. Pastore, Robert C. Williams +7 more
20153 citations
Semantic Scholar
Disruptive ARID1A Mutations in Follicular Lymphoma Impair DNA Repair Efficiency and Are Associated with Favorable Outcome in Patients Receiving First-Line Immunochemotherapy
D. Bararia, M. Heide, R. Welner, T. Romashova +9 more
20153 citations
Semantic Scholar
Spliceosomal Dysfunction Is a Critical Mediator of IDH2 Mutant Leukemogenesis
A. Yoshimi, Kuan-Ting Lin, D. Wiseman, A. Intlekofer +24 more
20172 citations
Semantic Scholar
Regulation of the Cyclin D1 Proto-Oncogene by Cell Cycle Regulatory MicroRNAs.
Anagha Borwankar, A. Pastore, A. Deshpande, Y. Zimmermann +3 more
20082 citations
Semantic Scholar
Inhibition of Proteasome Is Associated with Early Alterations of Cell Cycle Regulators and Induces Synergistic Antitumour Activities in Mantle Cell Lymphoma in a Sequence Dependent Manner.
A. Pastore, M. Rieken, O. Weigert, Y. Zimmermann +4 more
20052 citations
Semantic Scholar

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