V. Mustonen

Most-cited papers

The repertoire of mutational signatures in human cancer
L. Alexandrov, Jaegil Kim, N. Haradhvala, Mi-Ni Huang +17 more
2018Nature3,207 citations Open access
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Landscape of somatic mutations in 560 breast cancer whole genome sequences
S. Nik-Zainal, H. Davies, J. Staaf, M. Ramakrishna +84 more
2016Nature2,080 citations Open access
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Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma
I. Varela, P. Tarpey, K. Raine, Da-Chuan Huang +40 more
2011Nature1,266 citations Open access
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Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts
E. Papaemmanuil, M. Cazzola, J. Boultwood, L. Malcovati +44 more
2011New England Journal of Medicine1,259 citations Open access
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The evolutionary history of 2,658 cancers
M. Gerstung, C. Jolly, I. Leshchiner, S. Dentro +66 more
2017Nature969 citations Open access
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Pathway and Network Analysis of Cancer Genomes
Pau Creixell, J. Reimand, S. Haider, Guan-Ming Wu +16 more
2015Nature Methods325 citations Open access
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Predicting evolution
M. Lässig, V. Mustonen, A. Walczak
2017Nature Ecology &Evolution310 citations
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A High-Definition View of Functional Genetic Variation from Natural Yeast Genomes
A. Bergström, J. Simpson, F. Salinas, Benjamin P. Barre +9 more
2014Molecular biology and evolution279 citations Open access
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From fitness landscapes to seascapes: non-equilibrium dynamics of selection and adaptation.
V. Mustonen, M. Lässig
2009Trends in Genetics264 citations
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High-Definition Reconstruction of Clonal Composition in Cancer
Andrej Fischer, I. Vázquez-García, Christopher J. R. Illingworth, V. Mustonen
2014Cell Reports184 citations Open access
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Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data
D. Moradigaravand, Martin Palm, A. Farewell, V. Mustonen +2 more
2018PLoS Comput. Biol.182 citations Open access
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Fitness flux and ubiquity of adaptive evolution
V. Mustonen, M. Lässig
2010Proceedings of the National Academy of Sciences of the United States of America178 citations Open access
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Computational approaches to identify functional genetic variants in cancer genomes
A. González-Pérez, V. Mustonen, B. Reva, G. Ritchie +24 more
2013Nature Methods169 citations Open access
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The evolutionary landscape of colorectal tumorigenesis
W. Cross, M. Kováč, V. Mustonen, D. Temko +29 more
2018Nature Ecology & Evolution141 citations Open access
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High-Resolution Mapping of Complex Traits with a Four-Parent Advanced Intercross Yeast Population
Francisco A. Cubillos, L. Parts, F. Salinas, A. Bergström +9 more
2013Genetics131 citations Open access
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Energy-dependent fitness: A quantitative model for the evolution of yeast transcription factor binding sites
V. Mustonen, J. Kinney, C. Callan, M. Lässig
2008Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
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Evolutionary population genetics of promoters: predicting binding sites and functional phylogenies.
V. Mustonen, M. Lässig
2005Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
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Emergent Neutrality in Adaptive Asexual Evolution
S. Schiffels, G. Szöllősi, V. Mustonen, M. Lässig
2011Genetics121 citations Open access
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EMu: probabilistic inference of mutational processes and their localization in the cancer genome
Andrej Fischer, Christopher J. R. Illingworth, P. Campbell, V. Mustonen
2013Genome Biology107 citations Open access
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The mutational signatures of formalin fixation on the human genome
Qing-Li Guo, Eszter Lakatos, I. Al Bakir, K. Curtius +2 more
2021Nature Communications101 citations Open access
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Quantifying Selection Acting on a Complex Trait Using Allele Frequency Time Series Data
Christopher J. R. Illingworth, L. Parts, S. Schiffels, Gianni Liti +1 more
2011Molecular biology and evolution69 citations Open access
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Adaptations to fluctuating selection in Drosophila
V. Mustonen, M. Lässig
2007Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
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Neutral tumor evolution?
M. Tarabichi, I. Martincorena, M. Gerstung, A. Leroi +67 more
2017Nature Genetics66 citations Open access
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Understanding and applying biological resilience, from genes to ecosystems
R. Thorogood, V. Mustonen, Alexandre Aleixo, P. Aphalo +21 more
2023npj Biodiversity65 citations Open access
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The value of monitoring to control evolving populations
Andrej Fischer, I. Vázquez-García, V. Mustonen
2014Proceedings of the National Academy of Sciences of the United States of America63 citations Open access
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Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies.
Thomas McKerrell, T. Moreno, H. Ponstingl, N. Bolli +28 more
2016Blood59 citations Open access
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Molecular evolution under fitness fluctuations.
V. Mustonen, M. Lässig
2008Physical Review Letters59 citations
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Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference
Christopher J. R. Illingworth, V. Mustonen
2011Genetics58 citations Open access
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Identifying Selection in the Within-Host Evolution of Influenza Using Viral Sequence Data
Christopher J. R. Illingworth, Andrej Fischer, V. Mustonen
2014PLoS Comput. Biol.53 citations Open access
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Clonal Heterogeneity Influences the Fate of New Adaptive Mutations
I. Vázquez-García, F. Salinas, Jing Li, Andrej Fischer +7 more
2016bioRxiv49 citations Open access
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Adenoma development in familial adenomatous polyposis and MUTYH‐associated polyposis: somatic landscape and driver genes
Mamunur Rashid, Andrej Fischer, Catherine H. Wilson, Jessamy Tiffen +8 more
2015Journal of Pathology49 citations Open access
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Portraits of genetic intra-tumour heterogeneity and subclonal selection across cancer types
S. Dentro, I. Leshchiner, K. Haase, M. Tarabichi +42 more
2018bioRxiv46 citations Open access
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Drug-induced resistance evolution necessitates less aggressive treatment
Teemu Kuosmanen, Johannes Cairns, Robert Noble, N. Beerenwinkel +2 more
2020bioRxiv38 citations Open access
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Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression
Jani V. Anttila, Mikhail Shubin, Johannes Cairns, Florian Borse +5 more
2019PLoS Comput. Biol.37 citations Open access
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Components of Selection in the Evolution of the Influenza Virus: Linkage Effects Beat Inherent Selection
Christopher J. R. Illingworth, V. Mustonen
2012PLoS Pathogens36 citations Open access
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Repeatable ecological dynamics govern the response of experimental communities to antibiotic pulse perturbation
Johannes Cairns, Roosa Jokela, L. Becks, V. Mustonen +1 more
2020Nature Ecology & Evolution35 citations Open access
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A method to infer positive selection from marker dynamics in an asexual population
Christopher J. R. Illingworth, V. Mustonen
2012Bioinform.27 citations Open access
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Steering and controlling evolution — from bioengineering to fighting pathogens
M. Laessig, V. Mustonen, Armita Nourmohammad
2023Nature reviews genetics26 citations Open access
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Numerical estimation of the asymptotic behaviour of solid partitions of an integer
V. Mustonen, R. Rajesh
200326 citations Open access
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Genomic Epidemiology and Evolution of Escherichia coli in Wild Animals in Mexico
R. Murphy, Martin Palm, V. Mustonen, J. Warringer +3 more
2020Msphere25 citations Open access
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Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales.
Jing Li, I. Vázquez-García, Karl Persson, A. González +7 more
2019Molecular biology and evolution23 citations Open access
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Germline Fitness-Based Scoring of Cancer Mutations
Andrej Fischer, C. Greenman, V. Mustonen
2011Genetics21 citations Open access
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Rapid identification of genes controlling virulence and immunity in malaria parasites
Hussein M. Abkallo, A. Martinelli, Megumi Inoue, A. Ramaprasad +15 more
2017PLoS Pathogens20 citations Open access
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Eco-evolutionary control of pathogens
M. Lässig, V. Mustonen
2019Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
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Pre-exposure of abundant species to disturbance improves resilience in microbial metacommunities
Johannes Cairns, S. Hogle, Elizaveta Alitupa, V. Mustonen +1 more
2025Nature Ecology & Evolution16 citations Open access
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Machine Learning Prediction of Resistance to Subinhibitory Antimicrobial Concentrations from Escherichia coli Genomes
Sam Benkwitz-Bedford, Martin Palm, Talip Yasir Demirtas, V. Mustonen +4 more
2021bioRxiv14 citations Open access
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GraphAlignment: Bayesian pairwise alignment of biological networks
Michael V. Kolar, J. Meier, V. Mustonen, M. Lässig +1 more
2012BMC Systems Biology14 citations Open access
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Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences
S. Nik-Zainal, H. Davies, J. Staaf, M. Ramakrishna +84 more
2019Nature13 citations Open access
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Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells
David A. Ellis, V. Mustonen, María Rodríguez-López, Charalampos Rallis +3 more
2018Genetics13 citations Open access
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Author Correction: The repertoire of mutational signatures in human cancer
L. Alexandrov, Jaegil Kim, N. Haradhvala, Mi-Ni Huang +17 more
2023Nature11 citations Open access
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