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Jessamy Tiffen · SciRah

Researcher profile · Semantic Scholar

Jessamy Tiffen

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Jessamy Tiffen — researcher profile on SciRah

h-index: 23
Works: 52
Citations: 2,567

Most-cited papers

POT1 loss-of-function variants predispose to familial melanoma
C. D. Robles-Espinoza, M. Harland, A. Ramsay, L. Aoude +26 more
2014Nature Genetics386 citations Open access
Semantic Scholar
Targeting glutamine transport to suppress melanoma cell growth
Qian Wang, K. Beaumont, N. Otte, J. Font +9 more
2014International Journal of Cancer221 citations Open access
Semantic Scholar
Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB
K. Gowrishankar, Dilini Gunatilake, S. Gallagher, Jessamy Tiffen +2 more
2015PLoS ONE218 citations Open access
Semantic Scholar
Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy.
A. Al Emran, Aniruddha Chatterjee, E. Rodger, Jessamy Tiffen +3 more
2019Trends in immunology185 citations Open access
Semantic Scholar
Targeting amino acid transport in metastatic castration-resistant prostate cancer: effects on cell cycle, cell growth, and tumor development.
Qian Wang, Jessamy Tiffen, C. Bailey, M. Lehman +10 more
2013Journal of the National Cancer Institute182 citations Open access
Semantic Scholar
Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.
Qian Wang, C. Bailey, C. Ng, Jessamy Tiffen +8 more
2011Cancer Research171 citations
Semantic Scholar
Inactivating CUX1 mutations promote tumorigenesis
C. Wong, I. Martincorena, A. Rust, Mamunur Rashid +15 more
2013Nature Genetics125 citations Open access
Semantic Scholar
Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo
Jessamy Tiffen, C. Bailey, C. Ng, J. Rasko +1 more
2010Molecular Cancer98 citations Open access
Semantic Scholar
Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling
A. Heinemann, C. Cullinane, R. De Paoli-Iseppi, J. Wilmott +11 more
2015OncoTarget82 citations Open access
Semantic Scholar
Control of NF‐kB activity in human melanoma by bromodomain and extra‐terminal protein inhibitor I‐BET151
S. Gallagher, Branka Mijatov, Dilini Gunatilake, K. Gowrishankar +9 more
2014Pigment Cell & Melanoma Research80 citations
Semantic Scholar
Marked Global DNA Hypomethylation Is Associated with Constitutive PD-L1 Expression in Melanoma
Aniruddha Chatterjee, E. Rodger, Antonio Ahn, P. Stockwell +7 more
2018iScience78 citations Open access
Semantic Scholar
Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes
Jessamy Tiffen, Dilini Gunatilake, S. Gallagher, K. Gowrishankar +12 more
2015OncoTarget78 citations Open access
Semantic Scholar
The epigenetic regulator I-BET151 induces BIM-dependent apoptosis and cell cycle arrest of human melanoma cells.
S. Gallagher, Branka Mijatov, Dilini Gunatilake, Jessamy Tiffen +9 more
2014Journal of Investigative Dermatology61 citations Open access
Semantic Scholar
EZH2 cooperates with DNA methylation to downregulate key tumour suppressors and interferon gene signatures in melanoma.
Jessamy Tiffen, S. Gallagher, F. Filipp, Dilini Gunatilake +9 more
2020Journal of Investigative Dermatology60 citations Open access
Semantic Scholar
HDAC inhibitors restore BRAF‐inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma
S. Gallagher, Dilini Gunatilake, K. Beaumont, D. Sharp +9 more
2018International Journal of Cancer56 citations Open access
Semantic Scholar
EZH2: an emerging role in melanoma biology and strategies for targeted therapy
Jessamy Tiffen, S. Gallagher, P. Hersey
2015Pigment Cell & Melanoma Research53 citations
Semantic Scholar
The cancer‐testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells
Jessamy Tiffen, C. Bailey, A. Marshall, Cynthia Metierre +5 more
2013International Journal of Cancer52 citations Open access
Semantic Scholar
Adenoma development in familial adenomatous polyposis and MUTYH‐associated polyposis: somatic landscape and driver genes
Mamunur Rashid, Andrej Fischer, Catherine H. Wilson, Jessamy Tiffen +8 more
2015Journal of Pathology49 citations Open access
Semantic Scholar
Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma
Jessamy Tiffen, Stephen Wilson, S. Gallagher, P. Hersey +1 more
2016Neoplasia46 citations Open access
Semantic Scholar
Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy
S. Gallagher, Jessamy Tiffen, P. Hersey
2015Cancers45 citations Open access
Semantic Scholar
EZH2 as a mediator of treatment resistance in melanoma
Jessamy Tiffen, S. Gallagher, Hsin-Yi Tseng, F. Filipp +2 more
2016Pigment Cell & Melanoma Research34 citations Open access
Semantic Scholar
Pretreatment Innate Cell Populations and CD4 T Cells in Blood Are Associated With Response to Immune Checkpoint Blockade in Melanoma Patients
Mehdi R. Pirozyan, H. McGuire, A. Al Emran, Hsin-Yi Tseng +8 more
2020Frontiers in Immunology27 citations Open access
Semantic Scholar
Lysine Demethylases: Promising Drug Targets in Melanoma and Other Cancers
G. Punnia-Moorthy, P. Hersey, A. Al Emran, Jessamy Tiffen
2021Frontiers in Genetics23 citations Open access
Semantic Scholar
Nicotinamide Inhibits T Cell Exhaustion and Increases Differentiation of CD8 Effector T Cells
S. Alavi, A. Al Emran, Hsin-Yi Tseng, Jessamy Tiffen +2 more
2022Cancers18 citations Open access
Semantic Scholar
Study of the Female Sex Survival Advantage in Melanoma—A Focus on X-Linked Epigenetic Regulators and Immune Responses in Two Cohorts
A. Al Emran, J. Nsengimana, G. Punnia-Moorthy, U. Schmitz +4 more
2020Cancers18 citations Open access
Semantic Scholar
Repurposing melanoma chemotherapy to activate inflammasomes in treatment of BRAF/MAPK inhibitor resistant melanoma
F. Ahmed, Hsin-Yi Tseng, Antonio Ahn, Dilini Gunatilake +7 more
2021bioRxiv17 citations Open access
Semantic Scholar
Co‐targeting bromodomain and extra‐terminal proteins and MCL1 induces synergistic cell death in melanoma
Hsin-Yi Tseng, Jan Dreyer, A. Al Emran, Dilini Gunatilake +9 more
2020International Journal of Cancer16 citations
Semantic Scholar
Targeting of cytosolic phospholipase A2α impedes cell cycle re-entry of quiescent prostate cancer cells
M. Yao, C. Xie, M. Kiang, Ying Teng +8 more
2015OncoTarget14 citations Open access
Semantic Scholar
Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response
Q. Lee, Renhua Song, Dang Bao Anh Phan, N. Pinello +13 more
2023Cellular and Molecular Life Sciences13 citations Open access
Semantic Scholar
Liver-specific deletion of miR-181ab1 reduces liver tumour progression via upregulation of CBX7
Jin-Biao Chen, Yang Zhao, Fan Zhang, Jia Li +13 more
2022Cellular and Molecular Life Sciences13 citations Open access
Semantic Scholar
A combination of epigenetic BET and CDK9 inhibitors for treatment of human melanoma.
A. Al Emran, Hsin-Yi Tseng, Dilini Gunatilake, Stuart J Cook +5 more
2021Journal of Investigative Dermatology13 citations
Semantic Scholar
Do innate killing mechanisms activated by inflammasomes have a role in treating melanoma?
A. Al Emran, Hsin-Yi Tseng, Mikaela Coleman, Jessamy Tiffen +5 more
2020Pigment Cell & Melanoma Research11 citations Open access
Semantic Scholar
BET inhibition sensitizes innate checkpoint inhibitor resistant melanoma to anti‐CTLA‐4 treatment
Hsin-Yi Tseng, Sara Alavi, S. Gallagher, H. McGuire +3 more
2024Pigment Cell & Melanoma Research8 citations Open access
Semantic Scholar
Sex bias of females in survival from cancer and infections. Is X the answer?
A. Al Emran, S. Gallagher, Jessamy Tiffen, P. Hersey
2021British Journal of Cancer8 citations Open access
Semantic Scholar
Shedding light on dabrafenib-induced fevers in patients with melanoma.
P. Hersey, Jessamy Tiffen, S. Gallagher
2019The Lancet Oncology4 citations
Semantic Scholar
X and Y Differences in Melanoma Survival Between the Sexes
Peter Hersey, Hsin-Yi Tseng, Sara Alavi, Jessamy Tiffen
2024Pigment Cell & Melanoma Research2 citations Open access
Semantic Scholar
Abstract 1676: EZH2 inhibitors in immunotherapy of melanoma
P. Hersey, S. Gallagher, Jessamy Tiffen, E. Shklovskaya +2 more
20171 citations
Semantic Scholar
Somatic copy number amplification and activating somatic mutations of EZH2 Y641 drive melanoma by epigenetic remodeling.
P. Hersey, Jessamy Tiffen, S. Gallagher, F. Filipp
20151 citations
Semantic Scholar
Combining BET and HDAC inhibitors to potentiate their effectiveness against melanoma and to suppress AKT and YAP signaling.
P. Hersey, A. Heinemann, C. Cullinane, S. Gallagher +3 more
20151 citations
Semantic Scholar
Mesenchymal Stem Cells as Suicide Gene Therapy Vehicles for Organ-Confined and Metastatic Prostate Cancer (PCa).
R. Martiniello-Wilks, S. Larsen, S. Flamant, Jessamy Tiffen +2 more
20071 citations
Semantic Scholar
Abstract 2882: The impact of high fat diet on tumor growth is dependent on fatty acid composition and tumor type
R. Simpson, Freya E. Edge, J. Conway, Hsin-Yi Tseng +9 more
2026Cancer Research0 citations
Semantic Scholar
Correction: Overexpression of VIRMA confers vulnerability to breast cancers via the m6A-dependent regulation of unfolded protein response
Q. Lee, Renhua Song, Dang Bao Anh Phan, N. Pinello +13 more
2023Cellular and Molecular Life Sciences0 citations Open access
Semantic Scholar
Abstract LB-177: BET and CDK9 protein inhibitors: Novel epigenetic therapy to synergistically kill human melanoma cells
A. Al Emran, Hsin-Yi Tseng, Dilini Gunatilake, Stuart J Cook +3 more
2020Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
Abstract 826: Global DNA methylation levels regulate PD-L1 expression in melanoma
Aniruddha Chatterjee, Antonio Ahn, E. Rodger, P. Stockwell +7 more
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 5190: EZH2 epigenetically silences anti-tumor immunity in melanoma via dual histone and DNA methylation
Jessamy Tiffen, Dilini Gunatilake, S. Gallagher, P. Hersey
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 1384: The epigenetic modifier EZH2 represses antitumor immunity in melanoma
Jessamy Tiffen, E. Shklovskaya, S. Gallagher, Dilini Gunatilake +1 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 5149: EZH2 as a novel therapeutic target in melanoma treatment
Jessamy Tiffen, Dilini Gunatilake, S. Gallagher, K. Gowrishankar +1 more
20140 citations
Semantic Scholar
Abstract 20: POT1 mutations predispose to familial melanoma
C. D. Robles-Espinoza, M. Harland, A. Ramsay, L. Aoude +26 more
20140 citations
Semantic Scholar
Abstract 2947: Regulation of PD-L1 expression in human melanoma by NF-kB
K. Gowrishankar, Dilini Gunatilake, S. Gallagher, Jessamy Tiffen +1 more
20140 citations
Semantic Scholar
Supplementary information Inactivating CUX1 mutations promote tumorigenesis
C. Wong, I. Martincorena, A. Rust, Mamunur Rashid +18 more
20130 citations
Semantic Scholar

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