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Guang-Li Yang · SciRah

Researcher profile · Semantic Scholar

Guang-Li Yang

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Guang-Li Yang — researcher profile on SciRah

h-index: 18
Works: 39
Citations: 2,292

Most-cited papers

Novel D761Y and Common Secondary T790M Mutations in Epidermal Growth Factor Receptor–Mutant Lung Adenocarcinomas with Acquired Resistance to Kinase Inhibitors
M. Balak, Yi-Xuan Gong, Gregory Riely, Romel Somwar +9 more
2006Clinical Cancer Research844 citations Open access
Semantic Scholar
CSF-1/CSF-1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in Sarcoma Microenvironment
T. Fujiwara, Mohamed A. Yakoub, A. Chandler, Alexander B. Christ +13 more
2021Molecular Cancer Therapeutics214 citations Open access
Semantic Scholar
The Polycomb Repressor Complex 1 Drives Double Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
Wenjing Su, Hyunho Han, Yan Wang, Boyu Zhang +13 more
2019Cancer Cell192 citations Open access
Semantic Scholar
Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines
Romel Somwar, H. Erdjument-Bromage, E. Larsson, David Shum +7 more
2011Proceedings of the National Academy of Sciences of the United States of America148 citations Open access
Semantic Scholar
CRISPR-Cas III-A Csm6 CARF domain is a ring nuclease triggering stepwise cA4 cleavage with ApA>p formation terminating RNase activity
N. Jia, Roger A. Jones, Guang-Li Yang, O. Ouerfelli +1 more
2019Molecules and Cells113 citations Open access
Semantic Scholar
Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells
Julien Vaubourgeix, G. Lin, Neeraj Dhar, Nicolas Chenouard +10 more
2015Cell Host and Microbe105 citations Open access
Semantic Scholar
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
H. Boutzen, E. Saland, C. Larrue, F. de Toni +23 more
2016Journal of Experimental Medicine80 citations Open access
Semantic Scholar
Diverted Total Synthesis Leads to the Generation of Promising Cell-Migration Inhibitors for Treatment of Tumor Metastasis: In vivo and Mechanistic Studies on the Migrastatin Core Ether Analog
T. Oskarsson, P. Nagorny, Isaac J. Krauss, L. Pérez +7 more
2010Journal of the American Chemical Society64 citations Open access
Semantic Scholar
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays.
Thorsten Maretzky, Guang-Li Yang, O. Ouerfelli, C. Overall +4 more
2009Biochemical Journal57 citations
Semantic Scholar
Structure and Activity of Human Mitochondrial Peptide Deformylase, a Novel Cancer Target
S. Escobar-Alvarez, Y. Goldgur, Guang-Li Yang, O. Ouerfelli +2 more
2009Journal of Molecular Biology55 citations Open access
Semantic Scholar
Distinct Spatiotemporal Dynamics of Peptidoglycan Synthesis between Mycobacterium smegmatis and Mycobacterium tuberculosis
H. Botella, Guang-Li Yang, O. Ouerfelli, S. Ehrt +2 more
2017mBio49 citations Open access
Semantic Scholar
Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Nicolas Lecomte, J. T. Njardarson, P. Nagorny, Guang-Li Yang +4 more
2011Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Inhibition of Human Peptide Deformylase Disrupts Mitochondrial Function
S. Escobar-Alvarez, J. Gardner, A. Sheth, G. Manfredi +4 more
2010Molecular and Cellular Biology47 citations Open access
Semantic Scholar
A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization
P. Wojnarowicz, R. L. Silva, Masayuki Ohnaka, Sang Bae Lee +29 more
2019Cell Reports45 citations Open access
Semantic Scholar
Dietary intake and glutamine-serine metabolism control pathologic vascular stiffness
N. Rachedi, Ying Tang, Yi-Yin Tai, Jing-Si Zhao +30 more
2024Cell Metabolism42 citations Open access
Semantic Scholar
Targeting eIF4A Dependent Translation of KRAS Signaling Molecules
Kamini Singh, Jianan Lin, Nicolas Lecomte, Prathibha Mohan +22 more
2021Cancer Research39 citations Open access
Semantic Scholar
High-Throughput Identification of Inhibitors of Human Mitochondrial Peptide Deformylase
C. Antczak, David Shum, S. Escobar, Bhramdeo Bassit +8 more
2007Journal of biomolecular screening33 citations Open access
Semantic Scholar
Confirmation of the Structures of Synthetic Derivatives of Migrastatin in the Light of Recently Disclosed Crystallographically Based Claims
P. Nagorny, Isaac J. Krauss, J. T. Njardarson, L. Pérez +4 more
2010Tetrahedron Letters18 citations Open access
Semantic Scholar
DEMONSTRATION OF MICROTUBULE-LIKE STRUCTURES FORMED WITH (−)-RHAZINILAM FROM PURIFIED TUBULIN OUTSIDE OF CELLS AND A SIMPLE TUBULIN-BASED ASSAY FOR EVALUATION OF ANALOG ACTIVITY
Michael C. Edler, Guang-Li Yang, M. Jung, Ruo-Li Bai +2 more
2009Archives of Biochemistry and Biophysics15 citations Open access
Semantic Scholar
Discovery of cytochrome bc1 complex inhibitors inspired by the natural product karrikinolide
Cheng Chen, Qiong-You Wu, Lian-Ying Shan, Bei Zhang +2 more
201614 citations
Semantic Scholar
Arabinose- and xylose-modified analogs of 2′,3′-cGAMP act as STING agonists
W. Xie, L. Lama, Xue-Jing Yang, V. Kuryavyi +8 more
2023Cell Chemical Biology12 citations Open access
Semantic Scholar
Liang-Ge-San: a classic traditional Chinese medicine formula, attenuates acute inflammation via targeting GSK3β
Li-Ling Yang, Li-jun Yan, Weifu Tan, Xiang-Jun Zhou +7 more
2023Frontiers in Pharmacology10 citations Open access
Semantic Scholar
Redirecting raltitrexed from cancer cell thymidylate synthase to Mycobacterium tuberculosis phosphopantetheinyl transferase
Amrita Singh, Samantha Ottavi, Inna V. Krieger, Kyle Planck +27 more
2024Science Advances9 citations Open access
Semantic Scholar
eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer
Jacob A Boyer, E. Rosen, Malvika Sharma, M. Dorso +23 more
2025Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
An 19F Magnetic Resonance–Based In Vivo Assay of Solid Tumor Methotrexate Resistance: Proof of Principle
W. Spees, T. Gade, Guang-Li Yang, W. Tong +3 more
2005Clinical Cancer Research7 citations
Semantic Scholar
Mechanistic details of the actinobacterial lyase-catalyzed degradation reaction of 2-hydroxyisobutyryl-CoA
M. Zahn, G. König, Huy Viet Cuong Pham, Barbara Seroka +5 more
2021Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Rizedisben in Minimally Invasive Surgery
Samuel A. Gold, Maria M. Pere, M. Assel, Alex D. Doudt +24 more
2025JAMA Surgery5 citations
Semantic Scholar
Comparison of: (2S,4R)-4-[18F]Fluoroglutamine, [11C]Methionine, and 2-Deoxy-2-[18F]Fluoro-D-Glucose and Two Small-Animal PET/CT Systems Imaging Rat Gliomas
M. Miner, H. Liljenbäck, J. Virta, S. Helin +10 more
2021Frontiers in Oncology5 citations Open access
Semantic Scholar
A fluorine-labeled methotrexate as a probe for monitoring tumor antifolate pharmacokinetics: synthesis, in vitro cytotoxicity, and pilot in vivo 19F magnetic resonance spectra.
W. Spees, Guang-Li Yang, D. Veach, M. Rubio +2 more
2003Molecular Cancer Therapeutics5 citations
Semantic Scholar
The Combination of ATRA and Dasatinib for Differentiation Therapy in Acute Myeloid Leukemias with IDH Mutations
H. Boutzen, E. Saland, Mathilde Cathebras, C. Larrue +15 more
20154 citations
Semantic Scholar
eIF4A controls translation of estrogen receptor alpha and is a therapeutic target in advanced breast cancer
Jacob A Boyer, Malvika Sharma, M. Dorso, N. Mai +22 more
2024bioRxiv3 citations Open access
Semantic Scholar
Role of p38 Signaling Pathway in Pentagastrin-Regulated Cell Proliferation of Colorectal Carcinoma Cell Line HT-29
Jia-Ding Mao, Pei Wu, Jian Wu, L. Tao +4 more
20161 citations Open access
Semantic Scholar
Retraction Note: NSD2 targeting reverses plasticity and drug resistance in prostate cancer
Jia J. Li, A. Vasciaveo, Dimitris Karagiannis, Zhen Sun +25 more
2026Nature0 citations Open access
Semantic Scholar
Dual Fluorescence Isogenic Synthetic Lethal Kinase Screen and High-Content Secondary Screening for MUC16/CA125 Selective Agents
T. Rao, Mengyao Xu, S. Eng, Guang-Li Yang +10 more
2022Molecular Cancer Therapeutics0 citations Open access
Semantic Scholar
Characterization of Phosphopantetheinyl Hydrolase from Mycobacterium tuberculosis
Shilpika Pandey, Amrita Singh, Guang-Li Yang, Felipe B. d’Andrea +13 more
2021Microbiology spectrum0 citations Open access
Semantic Scholar
Author response for "Comparative analysis of the superoxide dismutase (SOD) gene family in Cetartiodactyla"
Ran Tian, Yuepan Geng, Han Guo, Chenju Yang +2 more
20210 citations
Semantic Scholar
Abstract 1531: The Polycomb repressor complex 1 promotes recruitment of myeloid-derived suppressor cells and immune evasion during bone colonization in castration-resistant prostate cancer
Wenjing Su, Boyu Zhang, Hyunho Han, G. Chakraborty +7 more
2019Immunology0 citations
Semantic Scholar
Abstract 4975: A small molecule pan Id protein antagonist shows strong antitumor activity
P. Wojnarowicz, Bina Desai, Yvette Chin, Sang Bae Lee +21 more
20170 citations
Semantic Scholar
NovelD761YandCommonSecondary T790MMutationsinEpidermal Growth Factor Receptor^Mutant LungAdenocarcinomaswith AcquiredResistance toKinase Inhibitors
M. Balak, Yi-Xuan Gong, Gregory Riely, Romel Somwar +9 more
20060 citations
Semantic Scholar
In vitro conditions promoting the formation of both microtubules and spirals by the natural product (-)-rhazinilam
Michael C. Edler, Guang-Li Yang, W. Bornmann, E. Hamel
20040 citations
Semantic Scholar

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