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E. Saland · SciRah

Researcher profile · Semantic Scholar

E. Saland

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E. Saland — researcher profile on SciRah

h-index: 28
Works: 65
Citations: 3,864

Most-cited papers

Chemotherapy Resistant Human Acute Myeloid Leukemia Cells are Not Enriched for Leukemic Stem Cells but Require Oxidative Metabolism
T. Farge, E. Saland, F. de Toni, Nesrine Aroua +39 more
2017Cancer Discovery760 citations Open access
Semantic Scholar
Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy.
Ruxanda Moschoi, V. Imbert, Marielle Nebout, J. Chiche +13 more
2016Blood415 citations Open access
Semantic Scholar
Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
N. Jacque, A. Ronchetti, C. Larrue, G. Meunier +19 more
2015Blood351 citations Open access
Semantic Scholar
Metformin Inhibits Growth of Human Glioblastoma Cells and Enhances Therapeutic Response
J. Sesen, P. Dahan, S. Scotland, E. Saland +8 more
2015PLoS ONE208 citations Open access
Semantic Scholar
Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites
Claudie Bosc, Nicolas Broin, M. Fanjul, E. Saland +18 more
2020Nature Communications135 citations Open access
Semantic Scholar
Mitochondrial energetic and AKT status mediate metabolic effects and apoptosis of metformin in human leukemic cells
S. Scotland, E. Saland, N. Skuli, F. de Toni +20 more
2013Leukemia132 citations
Semantic Scholar
Proteasome inhibitors induce FLT3-ITD degradation through autophagy in AML cells.
C. Larrue, E. Saland, H. Boutzen, F. Vergez +8 more
2016Blood130 citations Open access
Semantic Scholar
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
L. Stuani, Marie Sabatier, E. Saland, Guillaume Cognet +49 more
2021Journal of Experimental Medicine120 citations Open access
Semantic Scholar
Dendrogenin A drives LXR to trigger lethal autophagy in cancers
Gregory Segala, M. David, P. de Médina, Mathias C. Poirot +31 more
2017Nature Communications109 citations Open access
Semantic Scholar
Oncogenic FLT3-ITD supports autophagy via ATF4 in acute myeloid leukemia
Q. Heydt, C. Larrue, E. Saland, S. Bertoli +5 more
2017Oncogene109 citations Open access
Semantic Scholar
Mitochondrial inhibitors circumvent adaptive resistance to venetoclax and cytarabine combination therapy in acute myeloid leukemia
Claudie Bosc, E. Saland, Aurélie Bousard, Noémie Gadaud +36 more
2021Nature Cancer101 citations
Semantic Scholar
The ROS/SUMO axis contributes to the response of acute myeloid leukemia cells to chemotherapeutic drugs.
G. Bossis, J. Sarry, C. Kifagi, M. Ristic +12 more
2014Cell Reports93 citations Open access
Semantic Scholar
Ferritin heavy/light chain (FTH1/FTL) expression, serum ferritin levels, and their functional as well as prognostic roles in acute myeloid leukemia
S. Bertoli, E. Paubelle, Emilie Bérard, E. Saland +13 more
2018European Journal of Haematology91 citations
Semantic Scholar
C/EBPa confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress-induced ferroptosis in FLT3-mutant leukemia.
Marie Sabatier, R. Birsen, Laura Lauture, Sarah Mouche +53 more
2023Cancer Discovery80 citations Open access
Semantic Scholar
Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia
H. Boutzen, E. Saland, C. Larrue, F. de Toni +23 more
2016Journal of Experimental Medicine80 citations Open access
Semantic Scholar
A robust and rapid xenograft model to assess efficacy of chemotherapeutic agents for human acute myeloid leukemia
E. Saland, H. Boutzen, R. Castellano, L. Pouyet +11 more
2015Blood Cancer Journal77 citations Open access
Semantic Scholar
TOM1 is a PI5P effector involved in the regulation of endosomal maturation
Frédéric Boal, Rana Mansour, M. Gayral, E. Saland +7 more
2015Journal of Cell Science67 citations
Semantic Scholar
Arabinogalactan protein 31 (AGP31), a putative network-forming protein in Arabidopsis thaliana cell walls?
May Hijazi, David Roujol, Huan Nguyen-Kim, Liliana Del Rocio Cisneros Castillo +3 more
2014Annals of Botany64 citations Open access
Semantic Scholar
Antileukemic Activity of 2-Deoxy-d-Glucose through Inhibition of N-Linked Glycosylation in Acute Myeloid Leukemia with FLT3-ITD or c-KIT Mutations
C. Larrue, E. Saland, F. Vergez, Nizar Serhan +7 more
2015Molecular Cancer Therapeutics63 citations
Semantic Scholar
Extracellular ATP and CD39 activate cAMP-mediated mitochondrial stress response to promote cytarabine resistance in acute myeloid leukemia
Nesrine Aroua, Emeline Boet, M. Ghisi, Marie-Laure Nicolau-Travers +29 more
2019bioRxiv62 citations Open access
Semantic Scholar
Adrenomedullin-CALCRL axis controls relapse-initiating drug tolerant acute myeloid leukemia cells
C. Larrue, N. Guiraud, P. Mouchel, Marine Dubois +21 more
2020Nature Communications61 citations Open access
Semantic Scholar
Dexamethasone in hyperleukocytic acute myeloid leukemia
S. Bertoli, M. Picard, Emilie Bérard, E. Griessinger +16 more
2018Haematologica60 citations Open access
Semantic Scholar
Stable Isotope Labeling Highlights Enhanced Fatty Acid and Lipid Metabolism in Human Acute Myeloid Leukemia
L. Stuani, F. Riols, P. Millard, Marie Sabatier +9 more
2018International Journal of Molecular Sciences58 citations Open access
Semantic Scholar
Knockout of Vdac1 activates hypoxia-inducible factor through reactive oxygen species generation and induces tumor growth by promoting metabolic reprogramming and inflammation
M. Brahimi-Horn, Sandy Giuliano, E. Saland, S. Lacas-Gervais +15 more
2015Cancer & Metabolism57 citations Open access
Semantic Scholar
Targeting Myeloperoxidase Disrupts Mitochondrial Redox Balance and Overcomes Cytarabine Resistance in Human Acute Myeloid Leukemia.
Mohsen Hosseini, H. Rezvani, Nesrine Aroua, Claudie Bosc +13 more
2019Cancer Research56 citations
Semantic Scholar
CD36 Drives Metastasis and Relapse in Acute Myeloid Leukemia
T. Farge, Jean Nakhle, Damien Lagarde, Guillaume Cognet +27 more
2023Cancer Research52 citations Open access
Semantic Scholar
Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia
C. Larrue, Q. Heydt, E. Saland, H. Boutzen +4 more
2019Oncogenesis31 citations Open access
Semantic Scholar
RSK2 is a new Pim2 target with pro-survival functions in FLT3-ITD-positive acute myeloid leukemia
M. Hospital, A. Jacquel, F. Mazed, E. Saland +20 more
2018Leukemia29 citations
Semantic Scholar
Bcl-2 protein family expression pattern determines synergistic pro-apoptotic effects of BH3 mimetics with hemisynthetic cardiac glycoside UNBS1450 in acute myeloid leukemia
C. Cerella, A. Gaigneaux, Aloran Mazumder, J.-Y. Lee +10 more
2016Leukemia26 citations Open access
Semantic Scholar
Phenotypically-defined stages of leukemia arrest predict main driver mutations subgroups, and outcome in acute myeloid leukemia
F. Vergez, Laetitia Largeaud, S. Bertoli, Marie-Laure Nicolau +19 more
2022Blood Cancer Journal24 citations Open access
Semantic Scholar
The Nucleophosmin-Anaplastic Lymphoma Kinase Oncogene Interacts, Activates, and Uses the Kinase PIKfyve to Increase Invasiveness*
S. Dupuis-Coronas, F. Lagarrigue, D. Ramel, G. Chicanne +4 more
2011Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Oxidative Phosphorylation Fueled by Fatty Acid Oxidation Sensitizes Leukemic Stem Cells to Cold
E. Griessinger, D. Pereira-Martins, Marielle Nebout, Claudie Bosc +14 more
2023Cancer Research23 citations Open access
Semantic Scholar
Dendrogenin A Synergizes with Cytarabine to Kill Acute Myeloid Leukemia Cells In Vitro and In Vivo
Nizar Serhan, P. Mouchel, P. de Médina, Gregory Segala +13 more
2020Cancers22 citations Open access
Semantic Scholar
CDC25A governs proliferation and differentiation of FLT3-ITD acute myeloid leukemia
S. Bertoli, H. Boutzen, L. David, C. Larrue +15 more
2015OncoTarget22 citations Open access
Semantic Scholar
Targeting PP2A-dependent autophagy enhances sensitivity to ruxolitinib in JAK2V617F myeloproliferative neoplasms
Charly Courdy, Loïc Platteeuw, Charlotte Ducau, Isabelle De Araujo +15 more
2023Blood Cancer Journal15 citations Open access
Semantic Scholar
Activation of Vitamin D Receptor Pathway Enhances Differentiating Capacity in Acute Myeloid Leukemia with Isocitrate Dehydrogenase Mutations
Marie Sabatier, Emeline Boet, Sonia Zaghdoudi, N. Guiraud +17 more
2021Cancers14 citations Open access
Semantic Scholar
SHED-Dependent Oncogenic Signaling of the PEAK3 Pseudo-Kinase
Youcef Ounoughene, Elise Fourgous, Y. Boublik, E. Saland +7 more
2021Cancers13 citations Open access
Semantic Scholar
Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response
Sarah J. Skuli, A’ishah Bakayoko, Marisa Kruidenier, Bryan Manning +34 more
2025Leukemia11 citations Open access
Semantic Scholar
Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia
P. Mouchel, Nizar Serhan, R. Bétous, T. Farge +7 more
2020Cancers11 citations Open access
Semantic Scholar
Cytidine deaminase-dependent mitochondrial biogenesis as a potential vulnerability in pancreatic cancer cells
A. Frances, A. Lumeau, N. Béry, M. Gayral +12 more
2024Communications Biology5 citations Open access
Semantic Scholar
The Combination of ATRA and Dasatinib for Differentiation Therapy in Acute Myeloid Leukemias with IDH Mutations
H. Boutzen, E. Saland, Mathilde Cathebras, C. Larrue +15 more
20154 citations
Semantic Scholar
Chemoresistance of TP53 mutant AML requires the mevalonate byproduct, GGPP, for regulation of ROS and induction of a mitochondria stress response
Sarah J. Skuli, A’ishah Bakayoko, Marisa Kruidenier, Bryan Manning +29 more
2024bioRxiv3 citations Open access
Semantic Scholar
Mitochondrial determinants of response and resistance to venetoclax plus cytarabine duplet therapy in acute myeloid leukemia
Claudie Bosc, Noémie Gadaud, Aurélie Bousard, Marie Sabatier +21 more
2020bioRxiv3 citations Open access
Semantic Scholar
Cytosine Arabinoside Chemotherapy Does Not Enrich For Leukemic Stem Cells In Xenotransplantation Model Of Human Acute Myeloid Leukemia
Robin L. Perry, E. Saland, M. Sugita, M. David +10 more
20133 citations
Semantic Scholar
C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress in FLT3-mutant leukemia
Marie Sabatier, R. Birsen, Laura Lauture, J. Dehairs +34 more
2022bioRxiv2 citations Open access
Semantic Scholar
In Vivo Response to Cytarabine Chemotherapy Uncovers the Role of the Oxidative and Energetic Metabolism in the Chemoresistance of Human Primary AML Stem Cells
Nesrine Aroua, J. Sarry, F. de Toni, R. Carson +6 more
20152 citations
Semantic Scholar
[Mitohormesis: a key driver of the therapy resistance in cancer cells].
Emeline Boet, E. Saland, Sarah J. Skuli, Emmanuel Griessinger +1 more
2024Comptes rendus. Biologies0 citations Open access
Semantic Scholar
FAO-supported OxPhos leukemic stem cells are sensitive to cold
E. Griessinger, D. Pereira-Martins, Marielle Nebout, Claudie Bosc +14 more
2023bioRxiv0 citations Open access
Semantic Scholar
P477: PHENOTYPICALLY-DEFINED STAGES OF LEUKEMIA ARREST PREDICT MAIN DRIVER MUTATIONS SUBGROUPS, AND OUTCOME IN ACUTE MYELOID LEUKEMIA
F. Vergez, L. Largeaud, S. Bertoli, Marie-Laure Nicolau-Travers +19 more
2022HemaSphere0 citations Open access
Semantic Scholar
Cytidine deaminase regulates mitochondrial biogenesis in pancreatic cancer cells
A. Frances, A. Lumeau, L. Stuani, M. Gayral +11 more
2022bioRxiv0 citations Open access
Semantic Scholar

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