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J. T. Njardarson · SciRah

Researcher profile · Semantic Scholar

J. T. Njardarson

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J. T. Njardarson — researcher profile on SciRah

h-index: 38
Works: 120
Citations: 12K

Most-cited papers

Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticals.
Edon Vitaku, David T. Smith, J. T. Njardarson
2014Journal of Medicinal Chemistry4,704 citations
Semantic Scholar
Data-mining for sulfur and fluorine: an evaluation of pharmaceuticals to reveal opportunities for drug design and discovery.
Elizabeth A. Ilardi, Edon Vitaku, J. T. Njardarson
2014Journal of Medicinal Chemistry1,199 citations
Semantic Scholar
A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives
Nicholas A. McGrath, Matthew Brichacek, J. T. Njardarson
2010875 citations
Semantic Scholar
Analysis of US FDA-Approved Drugs Containing Sulfur Atoms
Kevin A. Scott, J. T. Njardarson
2018Topics in current chemistry769 citations
Semantic Scholar
Tumor Targeting with Antibody-Functionalized, Radiolabeled Carbon Nanotubes
M. McDevitt, D. Chattopadhyay, Barry J Kappel, J. Jaggi +5 more
2007Journal of Nuclear Medicine442 citations Open access
Semantic Scholar
From Oxiranes to Oligomers: Architectures of U.S. FDA Approved Pharmaceuticals Containing Oxygen Heterocycles.
Michael D Delost, David T. Smith, Benton J. Anderson, J. T. Njardarson
2018Journal of Medicinal Chemistry294 citations
Semantic Scholar
Beyond C, H, O, and N! Analysis of the elemental composition of U.S. FDA approved drug architectures.
Brandon R Smith, Candice M Eastman, J. T. Njardarson
2014Journal of Medicinal Chemistry271 citations
Semantic Scholar
Recent Advances in the Metal-Catalyzed Ring Expansions of Three- and Four-Membered Rings
Daniel J. Mack, J. T. Njardarson
2013252 citations
Semantic Scholar
A Survey of the Structures of US FDA Approved Combination Drugs.
Pradipta Das, Michael D Delost, M. Qureshi, David T. Smith +1 more
2018Journal of Medicinal Chemistry224 citations Open access
Semantic Scholar
Polymerizations with Elemental Sulfur: From Petroleum Refining to Polymeric Materials.
Taeheon Lee, P. T. Dirlam, J. T. Njardarson, R. Glass +1 more
2021Journal of the American Chemical Society191 citations
Semantic Scholar
PET Imaging of Soluble Yttrium-86-Labeled Carbon Nanotubes in Mice
M. McDevitt, D. Chattopadhyay, J. Jaggi, R. Finn +7 more
2007PLoS ONE181 citations Open access
Semantic Scholar
Synthetic analogues of migrastatin that inhibit mammary tumor metastasis in mice.
Dandan Shan, Lin Chen, J. T. Njardarson, C. Gaul +3 more
2005Proceedings of the National Academy of Sciences of the United States of America154 citations Open access
Semantic Scholar
The migrastatin family: discovery of potent cell migration inhibitors by chemical synthesis.
C. Gaul, J. T. Njardarson, Dandan Shan, David C. Dorn +5 more
2004Journal of the American Chemical Society148 citations
Semantic Scholar
Discovery of potent cell migration inhibitors through total synthesis: lessons from structure-activity studies of (+)-migrastatin.
J. T. Njardarson, C. Gaul, Dandan Shan, Xin-Yun Huang +1 more
2004Journal of the American Chemical Society141 citations
Semantic Scholar
Phenols in Pharmaceuticals: Analysis of a Recurring Motif.
Kevin A. Scott, Philip B. Cox, J. T. Njardarson
2022Journal of Medicinal Chemistry136 citations
Semantic Scholar
On the Mechanism of the Inverse Vulcanization of Elemental Sulfur: Structural Characterization of Poly(sulfur-random-(1,3-diisopropenylbenzene)).
Jia-Jing Bao, Kaitlyn P. Martin, Eunkyung Cho, K. Kang +6 more
2023Journal of the American Chemical Society87 citations
Semantic Scholar
The total synthesis of (+)-migrastatin.
C. Gaul, J. T. Njardarson, S. Danishefsky
2003Journal of the American Chemical Society84 citations
Semantic Scholar
Ring expansions of vinyloxiranes, -thiiranes, and -aziridines: synthetic approaches, challenges, and catalytic success stories.
Elizabeth A. Ilardi, J. T. Njardarson
2013Journal of Organic Chemistry74 citations
Semantic Scholar
Synthetic Efforts Toward [3.3.1] Bridged Bicyclic Phloroglucinol Natural Products
J. T. Njardarson
2011Tetrahedron70 citations Open access
Semantic Scholar
Catalytic ring expansion of vinyl oxetanes: asymmetric synthesis of dihydropyrans using chiral counterion catalysis.
Bo-Ying Guo, Gregg M. Schwarzwalder, J. T. Njardarson
2012Angewandte Chemie68 citations
Semantic Scholar
Creative approaches towards the synthesis of 2,5-dihydro- furans, thiophenes, and pyrroles. One method does not fit all!
Matthew Brichacek, J. T. Njardarson
2009Organic and biomolecular chemistry66 citations
Semantic Scholar
Lewis Acid Catalyzed [1,3]-Sigmatropic Rearrangement of Vinyl Aziridines
Matthew Brichacek, Dongeun Lee, J. T. Njardarson
2008Organic Letters64 citations Open access
Semantic Scholar
A Concise Ring-Expansion Route to the Compact Core of Platensimycin
Nicholas A. McGrath, Emily S. Bartlett, Satapanawat Sittihan, J. T. Njardarson
2009Angewandte Chemie62 citations Open access
Semantic Scholar
Stereospecific Ring Expansion of Chiral Vinyl Aziridines
Matthew Brichacek, Mauricio Navarro Villalobos, A. Plichta, J. T. Njardarson
2011Organic Letters60 citations Open access
Semantic Scholar
Copper-catalyzed rearrangement of vinyl oxiranes.
Lindsay A. Batory, Christine Mcinnis, J. T. Njardarson
2006Journal of the American Chemical Society60 citations
Semantic Scholar
Total Synthesis of Vinigrol
Qing-Liang Yang, J. T. Njardarson, C. Drăghici, Fang-Lin Li
2013Angewandte Chemie55 citations Open access
Semantic Scholar
Sulfenyl Chlorides: An Alternative Monomer Feedstock from Elemental Sulfur for Polymer Synthesis.
K. Kang, Chisom S. Olikagu, Taeheon Lee, Jia-Jing Bao +11 more
2022Journal of the American Chemical Society51 citations
Semantic Scholar
Highly selective copper-catalyzed ring expansion of vinyl thiiranes: application to synthesis of biotin and the heterocyclic core of plavix.
Erik Rogers, H. Araki, Lindsay A. Batory, Christine Mcinnis +1 more
2007Journal of the American Chemical Society51 citations Open access
Semantic Scholar
Rapid Assembly of Vinigrol’s Unique Carbocyclic Skeleton
Jason G. M. Morton, C. Drăghici, Laura D. Kwon, J. T. Njardarson
2009Organic Letters48 citations Open access
Semantic Scholar
Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin
Nicolas Lecomte, J. T. Njardarson, P. Nagorny, Guang-Li Yang +4 more
2011Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Stereoselective ring expansion of vinyl oxiranes: mechanistic insights and natural product total synthesis.
Matthew Brichacek, Lindsay A. Batory, J. T. Njardarson
2010Angewandte Chemie47 citations
Semantic Scholar
Asymmetric [3+2] Annulation Approach to 3-Pyrrolines: Concise Total Syntheses of (-)-Supinidine, (-)-Isoretronecanol, and (+)-Elacomine.
Isaac Chogii, J. T. Njardarson
2015Angewandte Chemie46 citations
Semantic Scholar
Intermolecular oxonium ylide mediated synthesis of medium-sized oxacycles.
Daniel J. Mack, Lindsay A. Batory, J. T. Njardarson
2012Organic Letters44 citations Open access
Semantic Scholar
An In-Pharm-ative Educational Poster Anthology Highlighting the Therapeutic Agents That Chronicle Our Medicinal History
Elizabeth A. Ilardi, Edon Vitaku, J. T. Njardarson
201337 citations
Semantic Scholar
Synthesis of allylic and homoallylic alcohols from unsaturated cyclic ethers using a mild and selective C-O reduction approach.
Daniel J. Mack, Bo-Ying Guo, J. T. Njardarson
2012Chemical Communications36 citations
Semantic Scholar
New mechanistic insights into the copper catalyzed ring expansion of vinyl aziridines: evidence in support of a copper(I) mediated pathway
Daniel J. Mack, J. T. Njardarson
201232 citations
Semantic Scholar
The strategic marriage of method and motif. Total synthesis of varitriol
Matthew Brichacek, Lindsay A. Batory, Nicholas A. McGrath, J. T. Njardarson
201032 citations
Semantic Scholar
Metal-Free Synthesis of Fluorinated Indoles Enabled by Oxidative Dearomatization.
Edon Vitaku, David T. Smith, J. T. Njardarson
2016Angewandte Chemie30 citations
Semantic Scholar
Catalytic Ring Expansion Adventures
J. T. Njardarson
201328 citations
Semantic Scholar
An Adler–Becker oxidation approach to vinigrol
Jason G. M. Morton, Laura D. Kwon, J. Freeman, J. T. Njardarson
200927 citations
Semantic Scholar
Total Synthesis of (±)-Phomoidride D.
Joyce C. Leung, Aaron A. Bedermann, J. T. Njardarson, D. Spiegel +13 more
2018Angewandte Chemie26 citations
Semantic Scholar
Dearomatization Approach to 2-Trifluoromethylated Benzofuran and Dihydrobenzofuran Products.
David T. Smith, Edon Vitaku, J. T. Njardarson
2017Organic Letters26 citations
Semantic Scholar
Evolution of an Oxidative Dearomatization Enabled Total Synthesis of Vinigrol
Qing-Liang Yang, C. Drăghici, J. T. Njardarson, Fang-Lin Li +2 more
2014Organic and biomolecular chemistry26 citations Open access
Semantic Scholar
New Class of Anion-Accelerated Amino-Cope Rearrangements as Gateway to Diverse Chiral Structures.
Isaac Chogii, Pradipta Das, Jason S. Fell, Kevin A. Scott +3 more
2017Journal of the American Chemical Society25 citations
Semantic Scholar
Mechanism and the origins of stereospecificity in copper-catalyzed ring expansion of vinyl oxiranes: a traceless dual transition-metal-mediated process.
T. Mustard, Daniel J. Mack, J. T. Njardarson, P. Cheong
2013Journal of the American Chemical Society25 citations
Semantic Scholar
Application of phenolic oxidation chemistry in synthesis: preparation of the BCE ring system of ryanodine
J. Wood, J. Graeber, J. T. Njardarson
200325 citations
Semantic Scholar
Syntheses and Structural Confirmations of Members of a Heterocycle-Containing Family of Labdane Diterpenoids
Daniel J. Mack, J. T. Njardarson
2012Angewandte Chemie23 citations Open access
Semantic Scholar
Z-Selective ring opening of vinyl oxetanes with dialkyl dithiophosphate nucleophiles.
Bo-Ying Guo, J. T. Njardarson
2013Chemical Communications22 citations
Semantic Scholar
An efficient oxidative dearomatization–radical cyclization approach to symmetrically substituted bicyclic guttiferone natural products
Nicholas A. McGrath, Joshua R. Binner, G. Markopoulos, Matthew Brichacek +1 more
2010Chemical Communications22 citations Open access
Semantic Scholar
An efficient substrate-controlled approach towards hypoestoxide, a member of a family of diterpenoid natural products with an inside-out [9.3.1]bicyclic core.
Nicholas A. McGrath, C. A. Lee, H. Araki, Matthew Brichacek +1 more
2008Angewandte Chemie20 citations
Semantic Scholar

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