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R. Tice · SciRah

Researcher profile · Semantic Scholar

R. Tice

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R. Tice — researcher profile on SciRah

h-index: 57
Works: 179
Citations: 29K

Most-cited papers

Recommendations for conducting the in vivo alkaline Comet assay. 4th International Comet Assay Workshop.
A. Hartmann, E. Agurell, C. Beevers, S. Brendler-Schwaab +7 more
2003Mutagenesis777 citations Open access
Semantic Scholar
Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?
M. Kadiiska, B. Gladen, D. Baird, D. Germolec +30 more
2005Free Radical Biology & Medicine684 citations
Semantic Scholar
Improving the Human Hazard Characterization of Chemicals: A Tox21 Update
R. Tice, C. Austin, R. Kavlock, J. Bucher
2013Environmental Health Perspectives592 citations Open access
Semantic Scholar
Fourth International Workgroup on Genotoxicity testing: results of the in vivo Comet assay workgroup.
B. Burlinson, R. Tice, G. Speit, E. Agurell +11 more
2007Mutation research493 citations
Semantic Scholar
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop.
D. Kirkland, S. Pfuhler, D. Tweats, M. Aardema +21 more
2007Mutation research433 citations
Semantic Scholar
The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology
A. Richard, Ruili Huang, S. Waidyanatha, P. Shinn +20 more
2020Chemical Research in Toxicology270 citations Open access
Semantic Scholar
Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening
M. Xia, Ruili Huang, K. Witt, Noel Southall +8 more
2007Environmental Health Perspectives262 citations Open access
Semantic Scholar
Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress
Daniel T. Shaughnessy, K. McAllister, L. Worth, A. Haugen +15 more
2014Environmental Health Perspectives259 citations Open access
Semantic Scholar
Genotoxicity of radiofrequency signals. I. Investigation of DNA damage and micronuclei induction in cultured human blood cells
R. Tice, Graham Hook, M. Donner, D. Mcree +1 more
2002Bioelectromagnetics244 citations
Semantic Scholar
The Tox21 robotic platform for assessment of environmental chemicals - from vision to reality
M. Attene-Ramos, N. Miller, Ruili Huang, Sam G. Michael +7 more
2013Drug Discovery Today228 citations Open access
Semantic Scholar
Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity.
M. Behl, Jui-Hua Hsieh, T. Shafer, W. Mundy +7 more
2015Neurotoxicology and Teratology208 citations
Semantic Scholar
Chemical Genomics Profiling of Environmental Chemical Modulation of Human Nuclear Receptors
Ruili Huang, M. Xia, Ming-Hsuang Cho, S. Sakamuru +8 more
2011Environmental Health Perspectives208 citations Open access
Semantic Scholar
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway
Ruili Huang, S. Sakamuru, Matt T. Martin, David M. Reif +18 more
2014Scientific Reports158 citations Open access
Semantic Scholar
Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential
M. Attene-Ramos, Ruili Huang, Sam G. Michael, K. Witt +5 more
2014Environmental Health Perspectives154 citations Open access
Semantic Scholar
ICCVAM evaluation of the murine local lymph node assay. Conclusions and recommendations of an independent scientific peer review panel.
J. Dean, L. Twerdok, R. Tice, D. Sailstad +2 more
2001Regulatory toxicology and pharmacology : RTP154 citations
Semantic Scholar
Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance.
A. Alzualde, M. Behl, Nisha S. Sipes, Jui-Hua Hsieh +5 more
2018Neurotoxicology and Teratology146 citations Open access
Semantic Scholar
Perspectives on Validation of High-Throughput Assays Supporting 21st Century Toxicity Testing
R. Judson, R. Kavlock, Matt T. Martin, David M. Reif +14 more
2013ALTEX141 citations Open access
Semantic Scholar
Comparative Neurotoxicity Screening in Human iPSC-derived Neural Stem Cells, Neurons and Astrocytes
Y. Pei, Jun Peng, M. Behl, Nisha S. Sipes +4 more
2015Brain Research125 citations Open access
Semantic Scholar
High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death
Jennifer T. Fox, S. Sakamuru, Ruili Huang, Nedelina Teneva +5 more
2012Proceedings of the National Academy of Sciences of the United States of America120 citations Open access
Semantic Scholar
ICCVAM evaluation of the murine local lymph node assay. Data analyses completed by the National Toxicology Program Interagency Center for the Evaluation of Alternative Toxicological Methods.
Karen E. Haneke, R. Tice, B. L. Carson, B. Margolin +1 more
2001Regulatory toxicology and pharmacology : RTP120 citations
Semantic Scholar
Neurite outgrowth in human induced pluripotent stem cell-derived neurons as a high-throughput screen for developmental neurotoxicity or neurotoxicity.
K. Ryan, O. Sirenko, F. Parham, Jui-Hua Hsieh +3 more
2016Neurotoxicology116 citations
Semantic Scholar
FutureTox II: in vitro data and in silico models for predictive toxicology.
T. Knudsen, D. Keller, M. Sander, E. Carney +8 more
2015Toxicological Sciences115 citations Open access
Semantic Scholar
Prediction of human population responses to toxic compounds by a collaborative competition
F. Eduati, L. Mangravite, Tao Wang, Hao Tang +120 more
2015Nature Biotechnology112 citations Open access
Semantic Scholar
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards.
D. Tweats, D. Blakey, R. Heflich, A. Jacobs +7 more
2007Mutation research110 citations
Semantic Scholar
Endocrine-Disrupting Chemicals (EDCs): In Vitro Mechanism of Estrogenic Activation and Differential Effects on ER Target Genes
Yin Li, Colin Luh, K. A. Burns, Y. Arao +4 more
2013Environmental Health Perspectives100 citations Open access
Semantic Scholar
Comparison of flow cytometry- and microscopy-based methods for measuring micronucleated reticulocyte frequencies in rodents treated with nongenotoxic and genotoxic chemicals.
K. Witt, E. Livanos, G. Kissling, D. Torous +3 more
2008Mutation research100 citations Open access
Semantic Scholar
Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study
N. Abdo, M. Xia, Chad C. Brown, O. Kosyk +13 more
2015Environmental Health Perspectives95 citations Open access
Semantic Scholar
The Next Generation of Risk Assessment Multi-Year Study—Highlights of Findings, Applications to Risk Assessment, and Future Directions
I. Cote, M. Andersen, G. Ankley, S. Barone +42 more
2016Environmental Health Perspectives87 citations Open access
Semantic Scholar
Application of a homogenous membrane potential assay to assess mitochondrial function.
S. Sakamuru, Xiao Li, M. Attene-Ramos, Ruili Huang +6 more
2012Physiological Genomics86 citations Open access
Semantic Scholar
In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model
O. Sirenko, Fabian A. Grimm, K. Ryan, Yasuhiro Iwata +8 more
2017Toxicology and Applied Pharmacology82 citations Open access
Semantic Scholar
A systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening
M. Attene-Ramos, Ruili Huang, S. Sakamuru, K. Witt +7 more
2013Chemical Research in Toxicology82 citations Open access
Semantic Scholar
JaCVAM-organized international validation study of the in vivo rodent alkaline comet assay for detection of genotoxic carcinogens: II. Summary of definitive validation study results.
Y. Uno, H. Kojima, Takashi Omori, R. Corvi +24 more
2015Mutation Research. Genetic Toxicology and Environmental Mutagenesis81 citations
Semantic Scholar
The Principles of Weight of Evidence Validation of Test Methods and Testing Strategies
M. Balls, P. Amcoff, S. Bremer, S. Casati +18 more
2006Alternatives to laboratory animals : ATLA81 citations Open access
Semantic Scholar
Evaluation of the genotoxicity of cell phone radiofrequency radiation in male and female rats and mice following subchronic exposure
S. Smith-Roe, M. Wyde, Matthew D. Stout, John Winters +8 more
2019Environmental and Molecular Mutagenesis74 citations Open access
Semantic Scholar
A High-Throughput Approach to Identify Specific Neurotoxicants / Developmental Toxicants in Human Neuronal Cell Function Assays
J. Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting +9 more
2018ALTEX70 citations Open access
Semantic Scholar
NTP-CERHR expert panel report on the reproductive and developmental toxicity of acrylamide.
J. Manson, M. Brabec, J. Buelke-Sam, G. Carlson +10 more
2005Birth defects research. Part B. Developmental and reproductice toxicology66 citations
Semantic Scholar
A Data Analysis Pipeline Accounting for Artifacts in Tox21 Quantitative High-Throughput Screening Assays
Jui-Hua Hsieh, Alexander Sedykh, Ruili Huang, M. Xia +1 more
2015Journal of biomolecular screening64 citations Open access
Semantic Scholar
Identification of chemical compounds that induce HIF-1alpha activity.
M. Xia, Ruili Huang, Yi Sun, G. Semenza +5 more
2009Toxicological Sciences64 citations Open access
Semantic Scholar
Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test.
D. Tweats, D. Blakey, R. Heflich, A. Jacobs +7 more
2007Mutation research64 citations Open access
Semantic Scholar
RNA-Seq Profiling Reveals Novel Hepatic Gene Expression Pattern in Aflatoxin B1 Treated Rats
B. Merrick, D. Phadke, S. Auerbach, D. Mav +3 more
2013PLoS ONE61 citations Open access
Semantic Scholar
Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies
M. Xia, Ruili Huang, Q. Shi, Windy A. Boyd +20 more
2018Environmental Health Perspectives55 citations Open access
Semantic Scholar
DNA methylation in mice is influenced by genetics as well as sex and life experience
Sara A. Grimm, T. Shimbo, Motoki Takaku, James W. Thomas +19 more
2019Nature Communications52 citations Open access
Semantic Scholar
Screening for Developmental Neurotoxicity at the National Toxicology Program: The Future Is Here.
M. Behl, K. Ryan, Jui-Hua Hsieh, F. Parham +9 more
2019Toxicological Sciences52 citations Open access
Semantic Scholar
The use of non-tumor data in cancer risk assessment: reflections on butadiene, vinyl chloride, and benzene.
R. Albertini, H. Clewell, M. Himmelstein, E. Morinello +7 more
2003Regulatory toxicology and pharmacology : RTP48 citations
Semantic Scholar
Skin sensitization in silico protocol
Candice Johnson, Ernst Ahlberg, L. Anger, Lisa Beilke +51 more
2020Regulatory toxicology and pharmacology : RTP44 citations Open access
Semantic Scholar
Moving Toward Integrating Gene Expression Profiling Into High-Throughput Testing: A Gene Expression Biomarker Accurately Predicts Estrogen Receptor α Modulation in a Microarray Compendium.
N. Ryan, B. Chorley, R. Tice, R. Judson +1 more
2016Toxicological Sciences44 citations Open access
Semantic Scholar
Profiling Environmental Chemicals for Activity in the Antioxidant Response Element Signaling Pathway Using a High Throughput Screening Approach
Sunita J. Shukla, Ruili Huang, Steven O. Simmons, R. Tice +5 more
2012Environmental Health Perspectives42 citations Open access
Semantic Scholar
Quantitative high-throughput screening for chemical toxicity in a population-based in vitro model.
E. Lock, N. Abdo, Ruili Huang, M. Xia +9 more
2012Toxicological Sciences41 citations Open access
Semantic Scholar
Estrogenic and anti-estrogenic activity of off-the-shelf hair and skin care products
S. L. Myers, Chun Z. Yang, G. Bittner, K. Witt +2 more
2014Journal of Exposure Science and Environmental Epidemiology37 citations Open access
Semantic Scholar
Identification of quaternary ammonium compounds as potent inhibitors of hERG potassium channels
M. Xia, S. Shahane, Ruili Huang, Steve Titus +7 more
2011Toxicology and Applied Pharmacology37 citations Open access
Semantic Scholar

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