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Simon Gutbier · SciRah

Researcher profile · Semantic Scholar

Simon Gutbier

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Simon Gutbier — researcher profile on SciRah

h-index: 20
Works: 36
Citations: 1,262

Most-cited papers

In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities
Béla Z. Schmidt, Martin Lehmann, Simon Gutbier, E. Nembo +9 more
2016Archives of Toxicology155 citations Open access
Semantic Scholar
Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening
Simon Gutbier, F. Wanke, Nadine Dahm, Anna Rümmelin +10 more
2020International Journal of Molecular Sciences118 citations Open access
Semantic Scholar
Transcriptional and metabolic adaptation of human neurons to the mitochondrial toxicant MPP+
A. Krug, Simon Gutbier, Liang Zhao, Dominik Pöltl +14 more
2014Cell Death and Disease103 citations Open access
Semantic Scholar
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect
Philipp F. Secker, S. Beneke, Nadja Schlichenmaier, J. Delp +3 more
2018Cell Death and Disease84 citations Open access
Semantic Scholar
Generation of genetically-modified human differentiated cells for toxicological tests and the study of neurodegenerative diseases.
Stefan Schildknecht, C. Karreman, Dominik Pöltl, L. Efremova +6 more
2013ALTEX84 citations Open access
Semantic Scholar
A High-Throughput Approach to Identify Specific Neurotoxicants / Developmental Toxicants in Human Neuronal Cell Function Assays
J. Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting +9 more
2018ALTEX70 citations Open access
Semantic Scholar
Alzheimer’s Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia
Marvin Reich, Iñaki Paris, M. Ebeling, Nadine Dahm +11 more
2021Frontiers in Immunology55 citations Open access
Semantic Scholar
Prevention of the degeneration of human dopaminergic neurons in an astrocyte co‐culture system allowing endogenous drug metabolism
L. Efremova, Stefan Schildknecht, Martina Adam, R. Pape +4 more
2015British Journal of Pharmacology55 citations Open access
Semantic Scholar
Prevention of neuronal apoptosis by astrocytes through thiol-mediated stress response modulation and accelerated recovery from proteotoxic stress
Simon Gutbier, Anna-Sophie Spreng, J. Delp, Stefan Schildknecht +5 more
2018Cell Death and Differentiation53 citations Open access
Semantic Scholar
Major changes of cell function and toxicant sensitivity in cultured cells undergoing mild, quasi-natural genetic drift
Simon Gutbier, P. May, Sylvie Berthelot, Abhimanyu Krishna +7 more
2018Archives of Toxicology49 citations Open access
Semantic Scholar
HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons
Sarah Kishinevsky, Tai Wang, Anna Rodina, Sun-Young Chung +25 more
2018Nature Communications46 citations Open access
Semantic Scholar
Incorporation of stem cell-derived astrocytes into neuronal organoids to allow neuro-glial interactions in toxicological studies.
Markus Brüll, Anna-Sophie Spreng, Simon Gutbier, Dominik Loser +6 more
2020ALTEX43 citations Open access
Semantic Scholar
Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation
L. Efremova, Petra Chovancová, Martina Adam, Simon Gutbier +2 more
2016Archives of Toxicology42 citations Open access
Semantic Scholar
Functional and phenotypic differences of pure populations of stem cell‐derived astrocytes and neuronal precursor cells
Susanne Kleiderman, J. Sá, Ana P. Teixeira, C. Brito +9 more
2016Glia41 citations Open access
Semantic Scholar
Ligand-dependent kinase activity of MERTK drives efferocytosis in human iPSC-derived macrophages
F. Wanke, Simon Gutbier, Anna Rümmelin, M. Steinberg +16 more
2021Cell Death and Disease38 citations Open access
Semantic Scholar
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants
Simon Gutbier, S. Kyriakou, Stefan Schildknecht, Anna-Katharina Ückert +11 more
2020Archives of Toxicology38 citations Open access
Semantic Scholar
Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances
N. Dreser, K. Madjar, Anna-Katharina Holzer, Marion Kapitza +17 more
2019Archives of Toxicology36 citations
Semantic Scholar
Stage‐specific metabolic features of differentiating neurons: Implications for toxicant sensitivity
J. Delp, Simon Gutbier, M. Cerff, Christin Zasada +14 more
2017Toxicology and Applied Pharmacology36 citations Open access
Semantic Scholar
CD22 Blockage Restores Age-Related Impairments of Microglia Surveillance Capacity
V. Aires, Claire Coulon-Bainier, Anto Pavlovic, M. Ebeling +5 more
2021Frontiers in Immunology31 citations Open access
Semantic Scholar
Conversion of Nonproliferating Astrocytes into Neurogenic Neural Stem Cells: Control by FGF2 and Interferon‐γ
Susanne Kleiderman, Simon Gutbier, Kemal Ugur Tufekci, Felipe Ortega +7 more
2016Stem Cells30 citations Open access
Semantic Scholar
Definition of the Neurotoxicity-Associated Metabolic Signature Triggered by Berberine and Other Respiratory Chain Inhibitors
Ilinca Suciu, J. Delp, Simon Gutbier, Julian Suess +5 more
2023Antioxidants12 citations Open access
Semantic Scholar
Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons
Ilinca Suciu, J. Delp, Simon Gutbier, Anna-Katharina Ückert +9 more
2023Antioxidants11 citations Open access
Semantic Scholar
Generation of an hiPSC-Derived Co-Culture System to Assess the Effects of Neuroinflammation on Blood–Brain Barrier Integrity
Daniel Bull, C. Schweitzer, Colette Bichsel, M. Britschgi +1 more
2022Cells11 citations Open access
Semantic Scholar
Identification of the bacterial metabolite aerugine as potential trigger of human dopaminergic neurodegeneration
Anna-Katharina Ückert, Sina Rütschlin, Simon Gutbier, Nathalie Christine Wörz +10 more
2023Environment International6 citations Open access
Semantic Scholar
A Novel Mitochondria-Targeting Iron Chelator Neuroprotects Multimodally via HIF-1 Modulation Against a Mitochondrial Toxin in a Dopaminergic Cell Model of Parkinson’s Disease
Belinda R. Fouché, S. Turner, R. Gorham, Eloise J. Stephenson +5 more
2022Molecular Neurobiology6 citations Open access
Semantic Scholar
Examination of microcystin neurotoxicity using central and peripheral human neurons.
Stefanie Klima, Ilinca Suciu, Lisa Hoelting, Simon Gutbier +3 more
2020ALTEX5 citations Open access
Semantic Scholar
Conversion of non-proliferating astrocytes into neurogenic neural stem cells: control by FGF2 and IFN-gamma
Susanne Kleiderman, Simon Gutbier, K. Tufekci, Felipe Ortega +7 more
20165 citations
Semantic Scholar
Corrigendum to Stage-specific metabolic features of differentiating neurons: Implications for toxicant sensitivity Toxicol Appl Pharmacol, 354 (2018) 64-80.
J. Delp, Simon Gutbier, M. Cerff, Christin Zasada +14 more
2019Toxicology and Applied Pharmacology1 citations Open access
Semantic Scholar
The complete guide to multiplex assays in drug discovery
Simon Gutbier, F. Wanke, Nadine Dahm, Anna Rümmelin +11 more
20210 citations
Semantic Scholar
Design and evaluation of bi-functional iron chelators for protection of dopaminergic neurons from toxicants
Simon Gutbier, S. Kyriakou, Stefan Schildknecht, Anna-Katharina Ückert +11 more
2020Archives of Toxicology0 citations Open access
Semantic Scholar
Corrigendum to A high-throughput approach to identify specific neurotoxicants / developmental toxicants in human neuronal cell function assays.
J. Delp, Simon Gutbier, Stefanie Klima, Lisa Hoelting +9 more
2019ALTEX0 citations Open access
Semantic Scholar
Canagliflozin mediated dual inhibition of mitochondrial glutamate dehydrogenase and complex I: an off-target adverse effect
Philipp F. Secker, S. Beneke, Nadja Schlichenmaier, J. Delp +3 more
2018Cell Death and Disease0 citations Open access
Semantic Scholar
Factors affecting toxicant sensitivity of LUHMES-derived human neurons
Simon Gutbier
20180 citations
Semantic Scholar
How cancer and stem cells perform aerobic glycolysis? – A quantitative and dynamic analysis of the CCM
Christin Zasada, M. Cerff, J. Delp, K. Nöh +5 more
20170 citations
Semantic Scholar
Metabolic flux analysis in human dopaminergic neurons under toxicant stress
J. Delp, S. Kempa, T. Hartung, Christin Zasada +4 more
20170 citations
Semantic Scholar
Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation
L. Efremova, Petra Chovancová, Martina Adam, Simon Gutbier +2 more
2016Archives of Toxicology0 citations Open access
Semantic Scholar

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