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S. Dove · SciRah

Researcher profile · Semantic Scholar

S. Dove

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S. Dove — researcher profile on SciRah

h-index: 32
Works: 125
Citations: 2,603

Most-cited papers

International Union of Basic and Clinical Pharmacology. CI. Structures and Small Molecule Modulators of Mammalian Adenylyl Cyclases
C. Dessauer, V. Watts, R. Ostrom, M. Conti +2 more
2017Pharmacological Reviews208 citations Open access
Semantic Scholar
Molecular and cellular analysis of human histamine receptor subtypes
R. Seifert, A. Strasser, Erich H. Schneider, D. Neumann +2 more
2012TIPS - Trends in Pharmacological Sciences162 citations Open access
Semantic Scholar
l-Ascorbic Acid 6-Hexadecanoate, a Potent Hyaluronidase Inhibitor
Alexander Botzki, D. Rigden, S. Braun, M. Nukui +6 more
2004Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Paradoxical Stimulatory Effects of the “Standard” Histamine H4-Receptor Antagonist JNJ7777120: the H4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity
R. Seifert, Erich H. Schneider, S. Dove, Irena Brunskole +3 more
2011Molecular Pharmacology96 citations
Semantic Scholar
Multiple Differences in Agonist and Antagonist Pharmacology between Human and Guinea Pig Histamine H1-Receptor
R. Seifert, K. Wenzel‐Seifert, T. Bürckstümmer, H. Pertz +4 more
2003Journal of Pharmacology and Experimental Therapeutics94 citations Open access
Semantic Scholar
Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases.
S. Mahboobi, S. Dove, A. Sellmer, M. Winkler +6 more
2009Journal of Medicinal Chemistry79 citations Open access
Semantic Scholar
Distinct interaction of human and guinea pig histamine H2-receptor with guanidine-type agonists.
M. T. Kelley, T. Bürckstümmer, Katharina Wenzel-Seifert, S. Dove +2 more
2001Molecular Pharmacology75 citations
Semantic Scholar
Impact of the DRY Motif and the Missing “Ionic Lock” on Constitutive Activity and G-Protein Coupling of the Human Histamine H4 Receptor
Erich H. Schneider, D. Schnell, A. Strasser, S. Dove +1 more
2010Journal of Pharmacology and Experimental Therapeutics72 citations
Semantic Scholar
Acylguanidines as bioisosteres of guanidines: NG-acylated imidazolylpropylguanidines, a new class of histamine H2 receptor agonists.
P. Ghorai, A. Kraus, M. Keller, Carsten Götte +9 more
2008Journal of Medicinal Chemistry70 citations Open access
Semantic Scholar
Bis(1H-2-indolyl)methanones as a novel class of inhibitors of the platelet-derived growth factor receptor kinase.
S. Mahboobi, S. Teller, Herwig Pongratz, Harald Hufsky +10 more
2002Journal of Medicinal Chemistry70 citations Open access
Semantic Scholar
Cytidylyl- and Uridylyl Cyclase Activity of Bacillus anthracis Edema Factor and Bordetella pertussis CyaA
Martin Göttle, S. Dove, F. Kees, J. Schlossmann +6 more
2010Biochemistry64 citations Open access
Semantic Scholar
Functional Selectivity of GPCR Ligand Stereoisomers: New Pharmacological Opportunities
R. Seifert, S. Dove
2009Molecular Pharmacology63 citations
Semantic Scholar
Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4 Receptor Agonists§
Patrick Igel, R. Geyer, A. Strasser, S. Dove +2 more
200962 citations Open access
Semantic Scholar
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.
A. Sellmer, H. Stangl, M. Beyer, Elisabeth Grünstein +10 more
2018Journal of Medicinal Chemistry60 citations Open access
Semantic Scholar
Novel bis(1H-indol-2-yl)methanones as potent inhibitors of FLT3 and platelet-derived growth factor receptor tyrosine kinase.
S. Mahboobi, Andrea Uecker, A. Sellmer, C. Cenac +12 more
2006Journal of Medicinal Chemistry52 citations Open access
Semantic Scholar
A Single Amino Acid Exchange Inverts Susceptibility of Related Receptor Tyrosine Kinases for the ATP Site Inhibitor STI-571* 210
F. Böhmer, L. Karagyozov, Andrea Uecker, H. Serve +3 more
2003Journal of Biological Chemistry52 citations Open access
Semantic Scholar
Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics
Heidrun Appl, Tobias Holzammer, S. Dove, E. Haen +2 more
2012Naunyn-Schmiedeberg's Archives of Pharmacology49 citations
Semantic Scholar
Expression and functional properties of canine, rat, and murine histamine H4 receptors in Sf9 insect cells
D. Schnell, Irena Brunskole, K. Ládová, Erich H. Schneider +4 more
2011Naunyn-Schmiedeberg's Archives of Pharmacology44 citations
Semantic Scholar
Histamine H4 receptor agonists.
Patrick Igel, S. Dove, A. Buschauer
2010Bioorganic & Medicinal Chemistry Letters44 citations Open access
Semantic Scholar
NG‐Acylated Aminothiazolylpropylguanidines as Potent and Selective Histamine H2 Receptor Agonists
A. Kraus, P. Ghorai, Tobias Birnkammer, D. Schnell +5 more
2009ChemMedChem44 citations
Semantic Scholar
The bivalent ligand approach leads to highly potent and selective acylguanidine-type histamine H₂ receptor agonists.
Tobias Birnkammer, Anja Spickenreither, Irena Brunskole, Miroslaw Lopuch +6 more
2012Journal of Medicinal Chemistry43 citations Open access
Semantic Scholar
Design of benzimidazole- and benzoxazole-2-thione derivatives as inhibitors of bacterial hyaluronan lyase.
S. Braun, Alexander Botzki, Sunnhild Salmen, C. Textor +3 more
2011European journal of medicinal chemistry40 citations Open access
Semantic Scholar
Constitutive Activity and Ligand Selectivity of Human, Guinea Pig, Rat, and Canine Histamine H2 Receptors
Hendrik C Preuss, P. Ghorai, A. Kraus, S. Dove +2 more
2007Journal of Pharmacology and Experimental Therapeutics40 citations Open access
Semantic Scholar
Molecular Analysis of the Interaction of Bordetella pertussis Adenylyl Cyclase with Fluorescent Nucleotides
Martin Göttle, S. Dove, P. Steindel, Yuequan Shen +4 more
2007Molecular Pharmacology40 citations Open access
Semantic Scholar
Novel 6-O-acylated vitamin C derivatives as hyaluronidase inhibitors with selectivity for bacterial lyases.
Martin Spickenreither, S. Braun, G. Bernhardt, S. Dove +1 more
2006Bioorganic & Medicinal Chemistry Letters38 citations
Semantic Scholar
Molecular Analysis of the Interaction of Anthrax Adenylyl Cyclase Toxin, Edema Factor, with 2′(3′)-O-(N-(methyl)anthraniloyl)-Substituted Purine and Pyrimidine Nucleotides
H. Taha, Jennifer Schmidt, Martin Göttle, S. Suryanarayana +7 more
2009Molecular Pharmacology37 citations Open access
Semantic Scholar
Synthesis and Neuropeptide Y Y1 Receptor Antagonistic Activity of N,N‐Disubstituted ω‐Guanidino‐ and ω‐Aminoalkanoic Acid Amides
M. Müller, S. Knieps, K. Gessele, S. Dove +2 more
199737 citations
Semantic Scholar
The Extracellular Loop 2 (ECL2) of the Human Histamine H4 Receptor Substantially Contributes to Ligand Binding and Constitutive Activity
David Wifling, G. Bernhardt, S. Dove, A. Buschauer
2015PLoS ONE35 citations Open access
Semantic Scholar
The Interleukin 1 (IL-1) Receptor Accessory Protein Toll/IL-1 Receptor Domain
Jürgen Radons, S. Dove, D. Neumann, R. Altmann +3 more
2003Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors.
M. Leonhardt, A. Sellmer, O. Krämer, S. Dove +4 more
2018European journal of medicinal chemistry34 citations Open access
Semantic Scholar
Structure-activity relationships of histamine H2 receptor ligands.
S. Dove, S. Elz, R. Seifert, A. Buschauer
2004Mini-Reviews in Medical Chemistry34 citations
Semantic Scholar
Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants
David Wifling, Karolin Löffel, Uwe Nordemann, A. Strasser +4 more
2015British Journal of Pharmacology33 citations Open access
Semantic Scholar
A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer.
Svenja Lier, A. Sellmer, F. Orben, S. Heinzlmeir +20 more
2021Bioorganic chemistry (Print)32 citations Open access
Semantic Scholar
Inhibition of FLT3 and PDGFR tyrosine kinase activity by bis(benzo[b]furan-2-yl)methanones.
S. Mahboobi, Andrea Uecker, C. Cenac, A. Sellmer +4 more
2007Bioorganic & Medicinal Chemistry27 citations Open access
Semantic Scholar
Theoretical studies on the interaction of partial agonists with the 5-HT2A receptor
Maria Elena Silva, Ralf Heim, A. Strasser, S. Elz +1 more
2011J. Comput. Aided Mol. Des.25 citations
Semantic Scholar
Structure-bias relationships for fenoterol stereoisomers in six molecular and cellular assays at the β2-adrenoceptor
Michael T. Reinartz, Solveig Kälble, Timo Littmann, T. Ozawa +4 more
2014Naunyn-Schmiedeberg's Archives of Pharmacology23 citations Open access
Semantic Scholar
Bis-Halogen-Anthraniloyl-Substituted Nucleoside 5′-Triphosphates as Potent and Selective Inhibitors of Bordetella pertussis Adenylyl Cyclase Toxin
Jens Geduhn, S. Dove, Yuequan Shen, Wei-Jen Tang +2 more
2011Journal of Pharmacology and Experimental Therapeutics23 citations Open access
Semantic Scholar
Homoarcyriaflavin: Synthesis of Ring-Expanded Arcyriaflavin Analogues.
S. Mahboobi, T. Burgemeister, S. Dove, S. Kuhr +1 more
1999Journal of Organic Chemistry21 citations
Semantic Scholar
Multi‐Component Protein – Protein Docking Based Protocol with External Scoring for Modeling Dimers of G Protein‐Coupled Receptors
A. Kaczor, Ramon Guixà-González, Pau Carrió, A. Poso +3 more
2015Molecular Informatics20 citations Open access
Semantic Scholar
Point mutations in the second extracellular loop of the histamine H2 receptor do not affect the species-selective activity of guanidine-type agonists
Hendrik C Preuss, P. Ghorai, A. Kraus, S. Dove +2 more
2007Naunyn-Schmiedeberg's Archives of Pharmacology20 citations Open access
Semantic Scholar
Mutations of Cys-17 and Ala-271 in the Human Histamine H2 Receptor Determine the Species Selectivity of Guanidine-Type Agonists and Increase Constitutive Activity
Hendrik C Preuss, P. Ghorai, A. Kraus, S. Dove +2 more
2007Journal of Pharmacology and Experimental Therapeutics19 citations Open access
Semantic Scholar
Inhibitors of Bacillus anthracis edema factor.
R. Seifert, S. Dove
2013Pharmacology and Therapeutics17 citations
Semantic Scholar
N4-monobutyryl-cCMP activates PKA RIα and PKA RIIα more potently and with higher efficacy than PKG Iα in vitro but not in vivo
Sabine Wolter, S. Dove, M. Golombek, F. Schwede +1 more
2014Naunyn-Schmiedeberg's Archives of Pharmacology16 citations Open access
Semantic Scholar
Towards selective inhibitors of adenylyl cyclase toxin from Bordetella pertussis.
R. Seifert, S. Dove
2012Trends in Microbiology16 citations
Semantic Scholar
Bacillus anthracis Edema Factor Substrate Specificity: Evidence for New Modes of Action
M. Gottle, S. Dove, R. Seifert
2012Toxins16 citations Open access
Semantic Scholar
Design of new benzoxazole-2-thione-derived inhibitors of Streptococcus pneumoniae hyaluronan lyase: structure of a complex with a 2-phenylindole.
D. Rigden, Alexander Botzki, M. Nukui, R. B. Mewbourne +7 more
2006Glycobiology16 citations
Semantic Scholar
The Interleukin 1 (IL-1) Receptor Accessory Protein Toll/IL-1 Receptor Domain ANALYSIS OF PUTATIVE INTERACTION SITES BY IN VITRO MUTAGENESIS AND MOLECULAR MODELING*
J. Radons, S. Dove, D. Neumann, R. Altmann +3 more
200316 citations
Semantic Scholar
Chiral NG-acylated hetarylpropylguanidine-type histamine H2 receptor agonists do not show significant stereoselectivity.
P. Ghorai, A. Kraus, Tobias Birnkammer, R. Geyer +5 more
2010Bioorganic & Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Structure-Activity Relationships of Nonpeptide Neuropeptide Y Receptor Antagonists
Albert Brennauer, S. Dove, A. Buschauer
200414 citations
Semantic Scholar
NPY Y1 antagonists: structure-activity relationships of arginine derivatives and hybrid compounds with arpromidine-like partial structures.
Iris Aiglstorfer, A. Uffrecht, K. Gessele, C. Moser +6 more
1998Regulatory Peptides14 citations
Semantic Scholar

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