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H. Pertz · SciRah

Researcher profile · Semantic Scholar

H. Pertz

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H. Pertz — researcher profile on SciRah

h-index: 22
Works: 73
Citations: 1,830

Most-cited papers

Curcumin analogs with altered potencies against HIV-1 integrase as probes for biochemical mechanisms of drug action.
A. Mazumder, N. Neamati, S. Sunder, J. Schulz +3 more
1997Journal of Medicinal Chemistry247 citations Open access
Semantic Scholar
(-)-Arctigenin as a lead structure for inhibitors of human immunodeficiency virus type-1 integrase.
E. Eich, H. Pertz, M. Kaloga, J. Schulz +3 more
1996Journal of Medicinal Chemistry178 citations Open access
Semantic Scholar
Lisuride, a Dopamine Receptor Agonist With 5-HT2B Receptor Antagonist Properties: Absence of Cardiac Valvulopathy Adverse Drug Reaction Reports Supports the Concept of a Crucial Role for 5-HT2B Receptor Agonism in Cardiac Valvular Fibrosis
C. Hofmann, U. Penner, R. Dorow, H. Pertz +5 more
2006Clinical neuropharmacology105 citations
Semantic Scholar
Effects of ginger constituents on the gastrointestinal tract: role of cholinergic M3 and serotonergic 5-HT3 and 5-HT4 receptors.
H. Pertz, J. Lehmann, R. Roth-Ehrang, S. Elz
2010Planta Medica97 citations
Semantic Scholar
Agonism at 5-HT2B receptors is not a class effect of the ergolines.
S. Jähnichen, R. Horowski, H. Pertz
2005European Journal of Pharmacology97 citations
Semantic Scholar
17-β-Estradiol Inhibits Transforming Growth Factor-β Signaling and Function in Breast Cancer Cells via Activation of Extracellular Signal-Regulated Kinase through the G Protein-Coupled Receptor 30
B. Kleuser, Daniela Malek, R. Gust, H. Pertz +1 more
2008Molecular Pharmacology94 citations
Semantic Scholar
Multiple Differences in Agonist and Antagonist Pharmacology between Human and Guinea Pig Histamine H1-Receptor
R. Seifert, K. Wenzel‐Seifert, T. Bürckstümmer, H. Pertz +4 more
2003Journal of Pharmacology and Experimental Therapeutics94 citations Open access
Semantic Scholar
Development of a new class of nonimidazole histamine H(3) receptor ligands with combined inhibitory histamine N-methyltransferase activity.
J. Apelt, X. Ligneau, H. Pertz, J. Arrang +4 more
2002Journal of Medicinal Chemistry64 citations Open access
Semantic Scholar
In‐vitro Pharmacology of Sarpogrelate and the Enantiomers of its Major Metabolite: 5‐HT2A Receptor Specificity, Stereoselectivity and Modulation of Ritanserin‐induced Depression of 5‐HT Contractions in Rat Tail Artery
H. Pertz, S. Elz
1995The Journal of pharmacy and pharmacology62 citations
Semantic Scholar
Mutational analysis of the histamine H1-receptor binding pocket of histaprodifens.
M. Bruysters, H. Pertz, A. Teunissen, R. Bakker +5 more
2004European Journal of Pharmacology49 citations
Semantic Scholar
In vitro Antispasmodic and Antiinflammatory Effects of Drosera rotundifolia
L. Krenn, Gabriele Beyer, H. Pertz, Elisabeth Karall +3 more
2004Arzneimittelforschung42 citations
Semantic Scholar
α2-Adrenoceptors are targets for antipsychotic drugs
J. Brosda, F. Jantschak, H. Pertz
2014Psychopharmacology38 citations
Semantic Scholar
Pergolide, terguride and N,N'-spacer-linked oligomers of both interact with 5-HT2A receptors of rat tail artery.
V. Křen, E. Eich, H. Pertz
2004Physiological Research36 citations Open access
Semantic Scholar
Evidence for 5-HT2B and 5-HT7 receptor-mediated relaxation in pulmonary arteries of weaned pigs
S. Jähnichen, E. Glusa, H. Pertz
2004Naunyn-Schmiedeberg's Archives of Pharmacology35 citations
Semantic Scholar
Antispasmodic activity of essential oil from Lippia dulcis Trev.
T. Görnemann, R. Nayal, H. Pertz, M. Melzig
2008Journal of Ethnopharmacology28 citations
Semantic Scholar
Pharmacological profile of the clonidine‐induced inhibition of vasodepressor sensory outflow in pithed rats: correlation with α2A/2C‐adrenoceptors
C. M. Villalón, J. A. Albarrán-Juárez, J. Lozano-Cuenca, H. Pertz +2 more
2008British Journal of Pharmacology28 citations Open access
Semantic Scholar
Pharmacological properties of a wide array of ergolines at functional alpha1-adrenoceptor subtypes
T. Görnemann, S. Jähnichen, B. Schurad, K. Latté +4 more
2007Naunyn-Schmiedeberg's Archives of Pharmacology28 citations
Semantic Scholar
Evidence that α1B-adrenoceptors are involved in noradrenaline-induced contractions of rat tail artery
S. Jähnichen, M. Eltze, H. Pertz
200428 citations
Semantic Scholar
Novel nonimidazole histamine H3 receptor antagonists: 1-(4-(phenoxymethyl)benzyl)piperidines and related compounds.
T. Mikó, X. Ligneau, H. Pertz, C. Ganellin +4 more
2003Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Nα-Imidazolylalkyl and Pyridylalkyl Derivatives of Histaprodifen: Synthesis and in Vitro Evaluation of Highly Potent Histamine H1-Receptor Agonists
Sonja Menghin, H. Pertz, K. Kramer, R. Seifert +2 more
200327 citations Open access
Semantic Scholar
New antithrombotic 1‐Phthalazinamines with Serotonin Antagonistic Properties
M. Johnsen, K. Rehse, H. Pertz, J. Stasch +1 more
2003Archiv der Pharmazie24 citations
Semantic Scholar
Development of FUB 181, a Selective Histamine H3‐Receptor Antagonist of High Oral in Vivo Potency with 4‐(?gv‐(Arylalkyloxy)alkyl)‐1H‐imidazole Structure
H. Stark, Annette Hüls, X. Ligneau, K. Purand +4 more
1998Archiv der Pharmazie23 citations
Semantic Scholar
Naturally Occurring Clavines: Antagonism/Partial Agonism at 5-HT2A Receptors and Antagonism at α1-Adrenoceptors in Blood Vessels
H. Pertz
1996Planta Medica22 citations
Semantic Scholar
Striking differences of action of lisuride stereoisomers at histamine H1 receptors
H. Pertz, T. Görnemann, B. Schurad, R. Seifert +1 more
2006Naunyn-Schmiedeberg's Archives of Pharmacology21 citations
Semantic Scholar
Pharmacological evidence that α2A- and α2C-adrenoceptors mediate the inhibition of cardioaccelerator sympathetic outflow in pithed rats
L. Cobos-Puc, C. Villalón, A. Sánchez-López, J. Lozano-Cuenca +3 more
200720 citations
Semantic Scholar
Characterization of the Molecular Fragment That Is Responsible for Agonism of Pergolide at Serotonin 5-Hydroxytryptamine2B and 5-Hydroxytryptamine2A Receptors
T. Görnemann, H. Hübner, P. Gmeiner, R. Horowski +3 more
2008Journal of Pharmacology and Experimental Therapeutics19 citations
Semantic Scholar
Search for influence of spatial properties on affinity at α1-adrenoceptor subtypes for phenylpiperazine derivatives of phenytoin.
J. Handzlik, H. Pertz, T. Görnemann, S. Jähnichen +1 more
2010Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Structural variations of 1-(4-(phenoxymethyl)benzyl)piperidines as nonimidazole histamine H3 receptor antagonists.
T. Mikó, X. Ligneau, H. Pertz, J. Arrang +4 more
2004Bioorganic & Medicinal Chemistry17 citations
Semantic Scholar
Synthesis and autoradiographic evaluation of a novel high-affinity Tc-99m ligand for the 5-HT2A receptor.
Hans-Juergen Pietzsch, Matthias Scheunemann, M. Kretzschmar, S. Elz +6 more
1999Nuclear Medicine and Biology17 citations
Semantic Scholar
Antiserotonergic Properties of Terguride in Blood Vessels, Platelets, and Valvular Interstitial Cells
Alexandra Kekewska, T. Görnemann, F. Jantschak, E. Glusa +1 more
2012Journal of Pharmacology and Experimental Therapeutics16 citations
Semantic Scholar
Structure-activity relationships of histamine H1-receptor agonists.
H. Pertz, S. Elz, W. Schunack
2004Mini-Reviews in Medical Chemistry16 citations
Semantic Scholar
Piperidino-hydrocarbon compounds as novel non-imidazole histamine H(3)-receptor antagonists.
G. Meier, X. Ligneau, H. Pertz, C. Ganellin +3 more
2002Bioorganic & Medicinal Chemistry16 citations
Semantic Scholar
A chemically defined 2,3-trans procyanidin fraction from willow bark causes redox-sensitive endothelium-dependent relaxation in porcine coronary arteries.
Aurica M Kaufeld, H. Pertz, H. Kolodziej
2014Journal of Natural Products13 citations
Semantic Scholar
Postjunctional α2C-adrenoceptors mediate vasoconstriction in rat tail artery: influence of precontraction and temperature on vasoreactivity
F. Jantschak, A. Popp, Raik A. Hofmann, C. Villalón +2 more
2010Naunyn-Schmiedeberg's Archives of Pharmacology12 citations
Semantic Scholar
Phenylephrine contracts porcine pulmonary veins via alpha(1B)-, alpha(1D)-, and alpha(2)-adrenoceptors.
T. Görnemann, C. Villalón, D. Centurión, H. Pertz
2009European Journal of Pharmacology12 citations
Semantic Scholar
Evidence that alpha(1B)-adrenoceptors are involved in noradrenaline-induced contractions of rat tail artery.
S. Jähnichen, M. Eltze, H. Pertz
2004European Journal of Pharmacology11 citations
Semantic Scholar
In vitro antiplasmodial activities of semisynthetic N,N'-spacer-linked oligomeric ergolines.
K. Jenett‐Siems, I. Köhler, Carola Kraft, H. Pertz +6 more
2004Bioorganic & Medicinal Chemistry11 citations
Semantic Scholar
2,3-cis-procyanidins elicit endothelium-dependent relaxation in porcine coronary arteries via activation of the PI3/Akt kinase signaling pathway.
Aurica M Kaufeld, H. Pertz, H. Kolodziej
2013Journal of Agricultural and Food Chemistry10 citations
Semantic Scholar
Characterisation of the relaxant response to raloxifene in porcine coronary arteries.
A. Moritz, O. Radtke, R. Gust, E. Glusa +1 more
2006European Journal of Pharmacology10 citations
Semantic Scholar
The Bulky N(6) Substituent of Cabergoline Is Responsible for Agonism of This Drug at 5-Hydroxytryptamine (5-HT)2A and 5-HT2B Receptors and Thus Is a Determinant of Valvular Heart Disease
Alexandra Kekewska, H. Hübner, P. Gmeiner, H. Pertz
2011Journal of Pharmacology and Experimental Therapeutics9 citations
Semantic Scholar
Pharmacological characterization of ergotamine-induced inhibition of the cardioaccelerator sympathetic outflow in pithed rats
L. Cobos-Puc, C. Villalón, A. Sánchez-López, M. Ramirez-Rosas +4 more
2009Naunyn-Schmiedeberg's Archives of Pharmacology9 citations
Semantic Scholar
ANTIMICROBIAL AND ANTITUMOR EFFECTS OF ERGOT ALKALOIDS AND THEIR DERIVATIVES
E. Eich, H. Pertz
20069 citations
Semantic Scholar
4-(ω-(Alkyloxy)alkyl)-1H-imidazole Derivatives as Histamine H3 Receptor Antagonists/Agonists
G. Meier, M. Krause, Annette Hüls, X. Ligneau +6 more
20049 citations Open access
Semantic Scholar
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery
S. Jähnichen, O. Radtke, H. Pertz
2004Naunyn-Schmiedeberg's Archives of Pharmacology9 citations
Semantic Scholar
Alpha2C-adrenoceptors play a prominent role in sympathetic constriction of porcine pulmonary arteries
F. Jantschak, H. Pertz
2012Naunyn-Schmiedeberg's Archives of Pharmacology8 citations
Semantic Scholar
Dopamine/serotonin receptor ligands. Part 17: a cross-target SAR approach: affinities of azecine-styled ligands for 5-HT(2A) versus D1 and D2 receptors.
C. Enzensperger, T. Görnemann, H. Pertz, J. Lehmann
2008Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Proterguride, a highly potent dopamine receptor agonist promising for transdermal administration in Parkinson's disease: interactions with alpha(1)-, 5-HT(2)- and H(1)-receptors.
B. Schurad, R. Horowski, S. Jähnichen, T. Görnemann +2 more
2006Life Science7 citations
Semantic Scholar
Effects of 2-bromoterguride, a dopamine D2 receptor partial agonist, on cognitive dysfunction and social aversion in rats
Emilia Tarland, R. Franke, H. Fink, H. Pertz +1 more
2017Psychopharmacology6 citations Open access
Semantic Scholar
Pharmacological evidence that alpha2A- and alpha2C-adrenoceptors mediate the inhibition of cardioaccelerator sympathetic outflow in pithed rats.
L. Cobos-Puc, C. Villalón, A. Sánchez-López, J. Lozano-Cuenca +3 more
2007European Journal of Pharmacology6 citations
Semantic Scholar
Development of FUB 181, a Selective Histamine H3-Receptor Antagonist of High Oral in vivo Potency with 4-(ω-(Arylalkyloxy)alkyl)-1H-imidazole Structure.
H. Stark, A. Huels, X. Ligneau, K. Purand +4 more
19985 citations
Semantic Scholar

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T. Görnemann×13
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T. Görnemann — researcher profile on SciRah
W. Schunack×11
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W. Schunack — researcher profile on SciRah
S. Jähnichen×9
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S. Jähnichen — researcher profile on SciRah
X. Ligneau×7
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X. Ligneau — researcher profile on SciRah

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J. Schwartz — researcher profile on SciRah

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H. Stark — researcher profile on SciRah

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S. Elz — researcher profile on SciRah

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J. Arrang — researcher profile on SciRah

D. Centurión×6

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D. Centurión — researcher profile on SciRah

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E. Eich — researcher profile on SciRah

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R. Horowski — researcher profile on SciRah

C. Villalón×5

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C. Villalón — researcher profile on SciRah