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A. Strasser · SciRah

Researcher profile · Semantic Scholar

A. Strasser

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A. Strasser — researcher profile on SciRah

h-index: 25
Works: 86
Citations: 1,839

Most-cited papers

Molecular and cellular analysis of human histamine receptor subtypes
R. Seifert, A. Strasser, Erich H. Schneider, D. Neumann +2 more
2012TIPS - Trends in Pharmacological Sciences162 citations Open access
Semantic Scholar
Paradoxical Stimulatory Effects of the “Standard” Histamine H4-Receptor Antagonist JNJ7777120: the H4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity
R. Seifert, Erich H. Schneider, S. Dove, Irena Brunskole +3 more
2011Molecular Pharmacology96 citations
Semantic Scholar
Species-dependent activities of G-protein-coupled receptor ligands: lessons from histamine receptor orthologs.
A. Strasser, Hans-Joachim Wittmann, A. Buschauer, Erich H. Schneider +1 more
2013TIPS - Trends in Pharmacological Sciences83 citations
Semantic Scholar
Synthesis, biological evaluation, and computational studies of Tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.
Fouad H Darras, Steffen Pockes, Guo-Zheng Huang, S. Wehle +5 more
2014ACS Chemical Neuroscience72 citations Open access
Semantic Scholar
Impact of the DRY Motif and the Missing “Ionic Lock” on Constitutive Activity and G-Protein Coupling of the Human Histamine H4 Receptor
Erich H. Schneider, D. Schnell, A. Strasser, S. Dove +1 more
2010Journal of Pharmacology and Experimental Therapeutics72 citations
Semantic Scholar
Intraligand phosphorescence of lead(II) β-diketonates under ambient conditions
A. Strasser, A. Vogler
200472 citations
Semantic Scholar
Binding Kinetics and Pathways of Ligands to GPCRs.
A. Strasser, Hans-Joachim Wittmann, R. Seifert
2017TIPS - Trends in Pharmacological Sciences62 citations
Semantic Scholar
Synthesis and Structure−Activity Relationships of Cyanoguanidine-Type and Structurally Related Histamine H4 Receptor Agonists§
Patrick Igel, R. Geyer, A. Strasser, S. Dove +2 more
200962 citations Open access
Semantic Scholar
Optical properties of thallium(I), lead(II) and bismuth(III) hexafluoroacetylacetonates. Intraligand phosphorescence under ambient conditions
A. Strasser, A. Vogler
200462 citations
Semantic Scholar
Phosphorescence of gadolinium(III) chelates under ambient conditions
A. Strasser, A. Vogler
200459 citations
Semantic Scholar
Interactions of Histamine H1-Receptor Agonists and Antagonists with the Human Histamine H4-Receptor
Karl‐Friedrich Deml, Silke Beermann, D. Neumann, A. Strasser +1 more
2009Molecular Pharmacology56 citations
Semantic Scholar
Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.
Dominik Dolles, M. Hoffmann, Sandra Gunesch, Oliviero Marinelli +9 more
2018Journal of Medicinal Chemistry55 citations Open access
Semantic Scholar
New insights into the cross-linking and degradation mechanism of Diels-Alder hydrogels.
S. Kirchhof, A. Strasser, Hans-Joachim Wittmann, Viktoria Messmann +3 more
2015Journal of materials chemistry. B52 citations Open access
Semantic Scholar
Interactions of recombinant human histamine H1, H2, H3, and H4 receptors with 34 antidepressants and antipsychotics
Heidrun Appl, Tobias Holzammer, S. Dove, E. Haen +2 more
2012Naunyn-Schmiedeberg's Archives of Pharmacology49 citations
Semantic Scholar
Pharmacological Profile of Histaprodifens at Four Recombinant Histamine H1 Receptor Species Isoforms
A. Strasser, B. Striegl, Hans-Joachim Wittmann, R. Seifert
2008Journal of Pharmacology and Experimental Therapeutics45 citations
Semantic Scholar
Ligand-Specific Contribution of the N Terminus and E2-Loop to Pharmacological Properties of the Histamine H1-Receptor
A. Strasser, Hans-Joachim Wittmann, R. Seifert
2008Journal of Pharmacology and Experimental Therapeutics36 citations
Semantic Scholar
Contribution of Binding Enthalpy and Entropy to Affinity of Antagonist and Agonist Binding at Human and Guinea Pig Histamine H1-Receptor
Hans-Joachim Wittmann, R. Seifert, A. Strasser
2009Molecular Pharmacology35 citations
Semantic Scholar
Structural Requirements for Inverse Agonism and Neutral Antagonism of Indole-, Benzimidazole-, and Thienopyrrole-Derived Histamine H4 Receptor Ligands
Erich H. Schneider, A. Strasser, Robin L. Thurmond, R. Seifert
2010Journal of Pharmacology and Experimental Therapeutics34 citations
Semantic Scholar
Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants
David Wifling, Karolin Löffel, Uwe Nordemann, A. Strasser +4 more
2015British Journal of Pharmacology33 citations Open access
Semantic Scholar
Comparison of the pharmacological properties of human and rat histamine H(3)-receptors.
D. Schnell, A. Strasser, R. Seifert
2010Biochemical Pharmacology33 citations
Semantic Scholar
Aminobenzimidazoles and Structural Isomers as Templates for Dual‐Acting Butyrylcholinesterase Inhibitors and hCB2R Ligands To Combat Neurodegenerative Disorders
Dominik Dolles, Martin Nimczick, M. Scheiner, Jacqueline Ramler +7 more
2016ChemMedChem31 citations
Semantic Scholar
Modulation of GPCRs by monovalent cations and anions
A. Strasser, Hans-Joachim Wittmann, Erich H. Schneider, R. Seifert
2014Naunyn-Schmiedeberg's Archives of Pharmacology31 citations
Semantic Scholar
Molecular Basis for the Selective Interaction of Synthetic Agonists with the Human Histamine H1-Receptor Compared with the Guinea Pig H1-Receptor
A. Strasser, Hans-Joachim Wittmann, M. Kunze, S. Elz +1 more
2009Molecular Pharmacology29 citations
Semantic Scholar
Role of the second and third extracellular loops of the histamine H4 receptor in receptor activation
Irena Brunskole, A. Strasser, R. Seifert, A. Buschauer
2011Naunyn-Schmiedeberg's Archives of Pharmacology27 citations
Semantic Scholar
Theoretical studies on the interaction of partial agonists with the 5-HT2A receptor
Maria Elena Silva, Ralf Heim, A. Strasser, S. Elz +1 more
2011J. Comput. Aided Mol. Des.25 citations
Semantic Scholar
Loratadine and analogues: discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B(0)AT2.
S. Cuboni, Christian Devigny, B. Hoogeland, A. Strasser +8 more
2014Journal of Medicinal Chemistry24 citations Open access
Semantic Scholar
Enhanced photoreactivity of zirconium(IV) and hafnium(IV) porphyrin complexes promoted by water molecules
G. Knör, A. Strasser
200523 citations
Semantic Scholar
Nanofibers resulting from cooperative electrostatic and hydrophobic interactions between peptides and polyelectrolytes of opposite charge.
Matthias Ferstl, A. Strasser, Hans-Joachim Wittmann, M. Drechsler +3 more
2011Langmuir21 citations
Semantic Scholar
Striking differences of action of lisuride stereoisomers at histamine H1 receptors
H. Pertz, T. Görnemann, B. Schurad, R. Seifert +1 more
2006Naunyn-Schmiedeberg's Archives of Pharmacology21 citations
Semantic Scholar
A Dynamic, Split-Luciferase-Based Mini-G Protein Sensor to Functionally Characterize Ligands at All Four Histamine Receptor Subtypes
Carina Höring, U. Seibel, Katharina Tropmann, Lukas Grätz +5 more
2020International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Influence of the N-terminus and the E2-loop onto the binding kinetics of the antagonist mepyramine and the partial agonist phenoprodifen to H(1)R.
Hans-Joachim Wittmann, R. Seifert, A. Strasser
2011Biochemical Pharmacology20 citations
Semantic Scholar
Coexisting intraligand fluorescence and phosphorescence of hafnium(IV) and thorium(IV) porphyrin complexes in solution
G. Knör, A. Strasser
200220 citations
Semantic Scholar
Optical properties of tris(cyclopentadienyl)gadolinium. Luminescence from an interligand triplet under ambient conditions
A. Strasser, A. Vogler
200319 citations
Semantic Scholar
Concept and Definitions in Cyclostratigraphy (Second Report of the Cyclostratigraphy Working Group)
F. Hilgen, W. Schwarzacher, A. Strasser
200418 citations
Semantic Scholar
The First Photochromic Affinity Switch for the Human Cannabinoid Receptor 2
Dominik Dolles, A. Strasser, Hans-Joachim Wittmann, Oliviero Marinelli +3 more
201817 citations Open access
Semantic Scholar
Analysis of the activation mechanism of the guinea-pig Histamine H1-receptor
A. Strasser, Hans-Joachim Wittmann
2007J. Comput. Aided Mol. Des.17 citations
Semantic Scholar
Dibenzo[b,f][1,4]oxazepines and dibenzo[b,e]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H1R, H4R, 5-HT2AR and other selected GPCRs.
Franziska Naporra, Susanne Gobleder, Hans-Joachim Wittmann, Julia Spindler +6 more
2016Pharmacological Research16 citations
Semantic Scholar
Nα-Methylated phenylhistamines exhibit affinity to the hH4R—a pharmacological and molecular modelling study
Hans-Joachim Wittmann, S. Elz, R. Seifert, A. Strasser
2011Naunyn-Schmiedeberg's Archives of Pharmacology16 citations
Semantic Scholar
Sodium binding to hH3R and hH4R — a molecular modeling study
Hans-Joachim Wittmann, R. Seifert, A. Strasser
2014Journal of Molecular Modeling14 citations
Semantic Scholar
Label-Free Investigations on the G Protein Dependent Signaling Pathways of Histamine Receptors
Ulla Seibel-Ehlert, Nicole Plank, A. Inoue, G. Bernhardt +1 more
2021International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Mepyramine-JNJ7777120-hybrid compounds show high affinity to hH(1)R, but low affinity to hH(4)R.
Eva Wagner, Hans-Joachim Wittmann, S. Elz, A. Strasser
2011Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Intraligand fluorescence and phosphorescence of tris(pyrazolyl) hydridoborate complexes
H. Kunkely, V. Pawlowski, A. Strasser, A. Vogler
200813 citations
Semantic Scholar
2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor-H1/H4-receptor selectivity.
S. G. Hammer, Susanne Gobleder, Franziska Naporra, Hans-Joachim Wittmann +3 more
2016Bioorganic & Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Binding pathway of histamine to the hH4R, observed by unconstrained molecular dynamics.
Hans-Joachim Wittmann, A. Strasser
2015Bioorganic & Medicinal Chemistry Letters11 citations
Semantic Scholar
Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor
Hans-Joachim Wittmann, R. Seifert, A. Strasser
2014In Silico Pharmacology11 citations Open access
Semantic Scholar
Pharmacological profile of astemizole-derived compounds at the histamine H1 and H4 receptor—H1/H4 receptor selectivity
Eva Wagner, Hans-Joachim Wittmann, S. Elz, A. Strasser
2013Naunyn-Schmiedeberg's Archives of Pharmacology11 citations
Semantic Scholar
Specific Engineered G Protein Coupling to Histamine Receptors Revealed from Cellular Assay Experiments and Accelerated Molecular Dynamics Simulations
Carina Höring, M. Conrad, Christian A. Söldner, Jinan Wang +3 more
2021International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Conformational Restriction and Enantioseparation Increase Potency and Selectivity of Cyanoguanidine-Type Histamine H4 Receptor Agonists.
R. Geyer, Uwe Nordemann, A. Strasser, Hans-Joachim Wittmann +1 more
2016Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
Synthesis and spectroscopic properties of anhydrotetracyclineplatinum(II)dichloride
A. Aly, A. Strasser, A. Vogler
200210 citations
Semantic Scholar
Molecular modeling studies give hint for the existence of a symmetric hβ2R-Gαβγ-homodimer
A. Strasser, Hans-Joachim Wittmann
2013Journal of Molecular Modeling8 citations
Semantic Scholar

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