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Juliet C. Gray · SciRah

Researcher profile · Semantic Scholar

Juliet C. Gray

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Juliet C. Gray — researcher profile on SciRah

h-index: 19
Works: 59
Citations: 1,189

Most-cited papers

Antibodies to Costimulatory Receptor 4‐1BB Enhance Anti‐tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function
Sarah L. Buchan, L. Dou, M. Remer, S. Booth +25 more
2018Immunity145 citations Open access
Semantic Scholar
Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy
J. Wienke, L. Visser, Waleed M. Kholosy, K. Keller +44 more
2022bioRxiv116 citations Open access
Semantic Scholar
antibody therapy is critically dependent on CD27 costimulation Eradication of lymphoma by CD8 T cells following anti-CD40 monoclonal
A. Tutt, A. Al-Shamkhani, M. Glennie, R. French +4 more
201383 citations
Semantic Scholar
Mutations in the transcriptional repressor REST predispose to Wilms tumor
S. Mahamdallie, S. Hanks, Kristen L. Karlin, Anna Zachariou +21 more
2015Nature Genetics72 citations
Semantic Scholar
PD-L1 and CD8+PD1+ lymphocytes exist as targets in the pediatric tumor microenvironment for immunomodulatory therapy
F. Chowdhury, Stuart N. Dunn, S. Mitchell, Toby Mellows +2 more
201566 citations Open access
Semantic Scholar
Optimising anti‐tumour CD8 T‐cell responses using combinations of immunomodulatory antibodies
Juliet C. Gray, R. French, S. James, A. Al-Shamkhani +2 more
2008European Journal of Immunology63 citations
Semantic Scholar
ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients.
A. Pearson, C. Rossig, G. Lesa, S. Diede +41 more
2020European Journal of Cancer60 citations Open access
Semantic Scholar
Immunomodulatory monoclonal antibodies combined with peptide vaccination provide potent immunotherapy in an aggressive murine neuroblastoma model
E. Williams, Stuart N. Dunn, S. James, P. Johnson +3 more
2013Clinical Cancer Research43 citations Open access
Semantic Scholar
Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments
Julia Moreno-Vicente, J. Willoughby, M. Taylor, S. Booth +10 more
2022Journal for ImmunoTherapy of Cancer42 citations Open access
Semantic Scholar
Immune characterization of pre-clinical murine models of neuroblastoma
E. Webb, S. Lanati, Carol Wareham, A. Easton +8 more
2020Scientific Reports33 citations Open access
Semantic Scholar
BEACON-Immuno: Results of the dinutuximab beta (dB) randomization of the BEACON-Neuroblastoma phase 2 trial—A European Innovative Therapies for Children with Cancer (ITCC–International Society of Paediatric Oncology Europe Neuroblastoma Group (SIOPEN) trial.
Juliet C. Gray, L. Moreno, Rebekah Weston, G. Barone +14 more
2022Journal of Clinical Oncology29 citations
Semantic Scholar
Randomization of dose-reduced subcutaneous interleukin-2 (scIL2) in maintenance immunotherapy (IT) with anti-GD2 antibody dinutuximab beta (DB) long-term infusion (LTI) in front–line high-risk neuroblastoma patients: Early results from the HR-NBL1/SIOPEN trial.
R. Ladenstein, U. Poetschger, D. Valteau-Couanet, Juliet C. Gray +16 more
2019Journal of Clinical Oncology29 citations
Semantic Scholar
Review: Targeting EZH2 in neuroblastoma.
Jinhui Gao, Claire Fosbrook, Jane Gibson, Timothy Underwood +2 more
2023Cancer Treatment Reviews26 citations Open access
Semantic Scholar
Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
E. Webb, Julia Moreno-Vincente, A. Easton, S. Lanati +7 more
2022iScience25 citations Open access
Semantic Scholar
DIPG harbour alterations targetable by MEK inhibitors, with acquired resistance mechanisms overcome by combinatorial inhibition
E. Izquierdo, Diana M. Carvalho, A. Mackay, Sara Temelso +33 more
2021Cancer Discovery24 citations Open access
Semantic Scholar
Randomized use of anti-GD2 antibody dinutuximab beta (DB) long-term infusion with and without subcutaneous interleukin-2 (scIL-2) in high-risk neuroblastoma patients with relapsed and refractory disease: Results from the SIOPEN LTI-trial.
H. Lode, D. Valteau-Couanet, Juliet C. Gray, R. Luksch +13 more
2019Journal of Clinical Oncology22 citations
Semantic Scholar
Impact of HACA on Immunomodulation and Treatment Toxicity Following ch14.18/CHO Long-Term Infusion with Interleukin-2: Results from a SIOPEN Phase 2 Trial
N. Siebert, S. Troschke-Meurer, M. Marx, M. Zumpe +12 more
2018Cancers22 citations Open access
Semantic Scholar
Clinical Phenotype and Management of Severe Neurotoxicity Observed in Patients with Neuroblastoma Treated with Dinutuximab Beta in Clinical Trials
A. Wieczorek, C. Manzitti, A. Garaventa, Juliet C. Gray +8 more
2022Cancers21 citations Open access
Semantic Scholar
Therapeutic potential of immunostimulatory monoclonal antibodies.
Juliet C. Gray, Peter W M Johnson, M. Glennie
2006Clinical science20 citations
Semantic Scholar
Toxicity and outcome of anti-GD2 antibody ch14.18/CHO in front-line, high-risk patients with neuroblastoma: Final results of the phase III immunotherapy randomisation (HR-NBL1/SIOPEN trial).
R. Ladenstein, U. Poetschger, Juliet C. Gray, D. Valteau-Couanet +16 more
201619 citations
Semantic Scholar
Immune reconstitution in children following chemotherapy for acute leukemia
A. Williams, J. Bate, R. Brooks, J. Chisholm +11 more
2020eJHaem18 citations Open access
Semantic Scholar
Tumor‐targeted and immune‐targeted monoclonal antibodies: Going from passive to active immunotherapy
A. Marabelle, Juliet C. Gray
2015Pediatric Blood & Cancer17 citations
Semantic Scholar
PD-1/PD-L1 blockade in paediatric cancers: What does the future hold?
Julia Moreno-Vicente, S. Beers, Juliet C. Gray
2019Cancer Letters16 citations
Semantic Scholar
Immunotherapy for neuroblastoma: Turning promise into reality
Juliet C. Gray, Janice A. Kohler
2009Pediatric Blood & Cancer15 citations
Semantic Scholar
Methodological advances in the discovery of novel neuroblastoma therapeutics
M. Segura, A. Soriano, J. Roma, O. Piskareva +10 more
2021Expert Opinion on Drug Discovery14 citations
Semantic Scholar
PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer
J. Bate, S. Baker, J. Breuer, J. Chisholm +14 more
2018Archives of Disease in Childhood14 citations Open access
Semantic Scholar
Erratum: Multisystem Lewy body disease and the other parkinsonian disorders
S. Mahamdallie, S. Hanks, Kristen L. Karlin, Anna Zachariou +21 more
2016Nature Genetics12 citations Open access
Semantic Scholar
Long-term infusion of anti-GD2 antibody ch14.18/CHO in combination with interleukin-2 (IL2) activity and efficacy in high-risk relapsed/refractory neuroblastoma patients.
H. Lode, D. Valteau-Couanet, A. Garaventa, Juliet C. Gray +15 more
201512 citations
Semantic Scholar
Prevalence of metachronous contralateral mature ovarian teratoma: A systematic review
D. Kiely, Carianne Lewis, Juliet C. Gray, N. Hall
2021Pediatric Blood & Cancer10 citations Open access
Semantic Scholar
13-valent Pneumococcal Conjugate Vaccine in children with acute lymphoblastic leukaemia: protective immunity can be achieved on completion of treatment.
J. Bate, R. Borrow, J. Chisholm, S. C. Clarke +10 more
2019Clinical Infectious Diseases10 citations Open access
Semantic Scholar
Osteonecrosis following treatment for childhood acute lymphoblastic leukaemia: The Southampton Children’s Hospital experience
A. Rhodes, Juliet C. Gray, N. Harvey, J. Davies +4 more
2017Journal of Children's Orthopaedics10 citations Open access
Semantic Scholar
National advisory panels for childhood cancer in the United Kingdom: An evaluation of current practice and a best practice statement for the future
Sarah Brown, Tanzina Chowdhury, M. Collin, R. Grundy +6 more
2022Pediatric Blood & Cancer8 citations Open access
Semantic Scholar
Hypercalcaemia secondary to ectopic parathyroid hormone expression in an adolescent with metastatic alveolar rhabdomyosarcoma
R. Brooks, C. Lord, J. Davies, Juliet C. Gray
2018Pediatric Blood & Cancer8 citations
Semantic Scholar
Immunotherapy with anti-GD2 antibody ch14.18/CHO±IL2 within the HR-NBL1/SIOPEN trial to improve outcome of high-risk neuroblastoma patients compared to historical controls.
R. Ladenstein, U. Poetschger, D. Couanet, Juliet C. Gray +16 more
20188 citations
Semantic Scholar
Phase II clinical trial with long-term infusion of anti-GD2 antibody ch14.18/CHO in combination with interleukin-2 (IL2) in patients with high risk neuroblastoma.
H. Lode, D. Valteau-Couanet, S. Troschke-Meurer, C. Manzitti +8 more
20168 citations
Semantic Scholar
Eradication of lymphoma by CD 8 T cells following anti-CD 40 monoclonal antibody therapy is critically dependent on CD 27 costimulation
R. French, V. Taraban, Graham R. Crowther, Tania F. Rowley +5 more
20078 citations
Semantic Scholar
The Role of Pre-Clinical 3-Dimensional Models of Osteosarcoma
Hannah L. Smith, S. Beers, Juliet C. Gray, J. Kanczler
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Development of immunomonitoring of antibody-dependent cellular cytotoxicity against neuroblastoma cells using whole blood
F. Chowdhury, H. Lode, M. Cragg, M. Glennie +1 more
2014Cancer Immunology and Immunotherapy7 citations Open access
Semantic Scholar
Improving paediatric antimicrobial stewardship in hospital-based settings: why, where and how?
E. Tanner, A. Munro, Juliet C. Gray, H. Green +5 more
2020JAC-Antimicrobial Resistance6 citations Open access
Semantic Scholar
Correlation of killer-cell Ig-like receptor (KIR) haplotypes and Fcγ-receptor polymorphisms with survival of high-risk relapsed/refractory neuroblastoma patients treated by long-term infusion of anti-GD2 antibody ch14.18/CHO.
H. Lode, S. Troschke-Meurer, D. Valteau-Couanet, A. Garaventa +13 more
20166 citations
Semantic Scholar
Narcolepsy with cataplexy as presenting symptom of occult neuroblastoma.
Claudine G. Sinsioco, K. Silver, K. Forrest, Juliet C. Gray +3 more
2013Pediatric Neurology6 citations
Semantic Scholar
Tri-Lineage Differentiation Potential of Osteosarcoma Cell Lines and Human Bone Marrow Stromal Cells from Different Anatomical Locations
Hannah L. Smith, Juliet C. Gray, S. Beers, J. Kanczler
2023International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
Paediatric ambiguous lineage leukaemia with monocytic differentiation at diagnosis: case series and review of literature
S. Tandon, Reginah Visser, Emma Astwood, J. Payne +4 more
2021British Journal of Haematology2 citations Open access
Semantic Scholar
Abstract A032: Immunotherapy with ch14.18/CHO in combination with IL2 is active and effective in high-risk relapsed/refractory neuroblastoma patients
H. Lode, D. Valteau-Couanet, A. Garaventa, Juliet C. Gray +16 more
20162 citations
Semantic Scholar
Neuroblastoma: a master of disguise and a challenge to cure
D. Calderoni, G. Barone, M. Elliott, D. Tweddle +2 more
2022Paediatrics & child health1 citations Open access
Semantic Scholar
A Case of Prepubertal Ovarian Tissue Cryopreservation in Metachronous Bilateral Mature Ovarian Teratoma Requiring Bilateral Oophorectomy
T. Malik, R. Wheeler, N. Hall, Juliet C. Gray
2022European Journal of Pediatric Surgery Reports1 citations Open access
Semantic Scholar
Risk factors in the HR-NBL-1/SIOPEN study in patients receiving dinutuximab beta (DB) based immunotherapy.
R. Ladenstein, U. Poetschger, D. Valteau-Couanet, Juliet C. Gray +15 more
20201 citations
Semantic Scholar
Overview of Monoclonal Antibody Therapies
Juliet C. Gray, P. Sondel
20181 citations
Semantic Scholar
Integrative transcriptomic and proteomic meta-analysis of Zika viral infection reveals potential mechanisms for oncolytic therapy in neuroblastoma
M. Sherwood, Yi-Lu Zhou, Yi Sui, Yi-Hua Wang +5 more
2023bioRxiv0 citations Open access
Semantic Scholar
CSIG-29. EMPLOYING THE ZIKA VIRUS AS ONCOLYTIC VIROTHERAPY AGAINST PAEDIATRIC NERVOUS SYSTEM CANCER CELLS
M. Sherwood, C. Kaid, T. Mitsugi, Yi-Lu Zhou +5 more
2022Neuro-Oncology0 citations Open access
Semantic Scholar

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