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C. Rossig · SciRah

Researcher profile · Semantic Scholar

C. Rossig

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C. Rossig — researcher profile on SciRah

h-index: 46
Works: 245
Citations: 8,825

Most-cited papers

Inotuzumab Ozogamicin in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia
D. Bhojwani, R. Sposto, N. Shah, V. Rodriguez +16 more
2018Leukemia210 citations Open access
Semantic Scholar
EZH2 Inhibition in Ewing Sarcoma Upregulates GD2 Expression for Targeting with Gene-Modified T Cells.
S. Kailayangiri, B. Altvater, S. Lesch, S. Balbach +16 more
2019Molecular Therapy103 citations Open access
Semantic Scholar
Overcoming Heterogeneity of Antigen Expression for Effective CAR T Cell Targeting of Cancers
S. Kailayangiri, B. Altvater, Malena Wiebel, Silke Jamitzky +1 more
2020Cancers100 citations Open access
Semantic Scholar
Design and Characterization of an “All-in-One” Lentiviral Vector System Combining Constitutive Anti-GD2 CAR Expression and Inducible Cytokines
Katharina Zimmermann, J. Kuehle, A. Dragon, Melanie Galla +12 more
2020Cancers98 citations Open access
Semantic Scholar
Blinatumomab in pediatric patients with relapsed/refractory acute lymphoblastic leukemia: results of the RIALTO trial, an expanded access study
F. Locatelli, G. Zugmaier, Noemi Mergen, P. Bader +7 more
2020Blood Cancer Journal88 citations Open access
Semantic Scholar
A Phase I study of inotuzumab ozogamicin in pediatric relapsed/refractory acute lymphoblastic leukemia (ITCC-059 study).
E. Brivio, F. Locatelli, M. Lopez-Yurda, A. Malone +17 more
2020Blood85 citations Open access
Semantic Scholar
Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050): a multicentre, open-label, multicohort, phase 1/2 study.
N. Gaspar, R. Venkatramani, S. Hecker-Nolting, S. G. Melcon +18 more
2021The Lancet Oncology67 citations Open access
Semantic Scholar
CD171- and GD2-specific CAR-T cells potently target retinoblastoma cells in preclinical in vitro testing
Lena Andersch, Josefine Radke, Anika Klaus, Silke Schwiebert +12 more
2019BMC Cancer63 citations Open access
Semantic Scholar
CD19 CAR T-cells for pediatric relapsed acute lymphoblastic leukemia with active CNS involvement: a retrospective international study
E. Jacoby, S. Ghorashian, B. Vormoor, B. De Moerloose +17 more
2022Leukemia61 citations Open access
Semantic Scholar
GMP-Compliant Manufacturing of TRUCKs: CAR T Cells targeting GD2 and Releasing Inducible IL-18
W. Glienke, A. Dragon, Katharina Zimmermann, A. Martyniszyn-Eiben +17 more
2022Frontiers in Immunology61 citations Open access
Semantic Scholar
ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients.
A. Pearson, C. Rossig, G. Lesa, S. Diede +41 more
2020European Journal of Cancer60 citations Open access
Semantic Scholar
Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050)☆
N. Gaspar, Q. Campbell-Hewson, S. G. Melcon, F. Locatelli +18 more
2021ESMO Open58 citations Open access
Semantic Scholar
CD19 CAR T cells are an effective therapy for posttransplant relapse in patients with B-lineage ALL: real-world data from Germany
P. Bader, C. Rossig, Martin Hutter, F. Ayuk +22 more
2023Blood Advances57 citations Open access
Semantic Scholar
Gemtuzumab ozogamicin in children with relapsed or refractory acute myeloid leukemia: a report by Berlin-Frankfurt-Münster study group
Naghmeh Niktoreh, Beate Lerius, M. Zimmermann, B. Gruhn +8 more
2018Haematologica53 citations Open access
Semantic Scholar
Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia
C. van Tilburg, T. Milde, R. Witt, J. Ecker +23 more
2019Clinical Epigenetics52 citations Open access
Semantic Scholar
Programmed cell death ligand 1 (PD‐L1) expression is not a predominant feature in Ewing sarcomas
Christian Spurny, S. Kailayangiri, Silke Jamitzky, B. Altvater +5 more
2018Pediatric Blood & Cancer46 citations
Semantic Scholar
VEGFR2 as a target for CAR T cell therapy of Ewing sarcoma
Alexander Englisch, B. Altvater, S. Kailayangiri, W. Hartmann +1 more
2020Pediatric Blood & Cancer44 citations Open access
Semantic Scholar
Cobimetinib in Pediatric and Young Adult Patients with Relapsed or Refractory Solid Tumors (iMATRIX-cobi): A Multicenter, Phase I/II Study
T. Trippett, H. Toledano, Q. Campbell-Hewson, A. Verschuur +14 more
2022Targeted oncology41 citations Open access
Semantic Scholar
SS18-SSX–Dependent YAP/TAZ Signaling in Synovial Sarcoma
I. Isfort, M. Cyra, S. Elges, S. Kailayangiri +15 more
2019Clinical Cancer Research40 citations Open access
Semantic Scholar
Carbohydrate Targets for CAR T Cells in Solid Childhood Cancers
C. Rossig, S. Kailayangiri, Silke Jamitzky, B. Altvater
2018Frontiers in Oncology40 citations Open access
Semantic Scholar
Phosphatidylinositol-3-kinase (PI3K)/Akt Signaling is Functionally Essential in Myxoid Liposarcoma
M. Trautmann, M. Cyra, I. Isfort, Birte Jeiler +12 more
2019Molecular Cancer Therapeutics35 citations Open access
Semantic Scholar
Paediatric Strategy Forum for medicinal product development of chimeric antigen receptor T-cells in children and adolescents with cancer ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration
A. Pearson, C. Rossig, C. Mackall, N. Shah +50 more
2021European Journal of Cancer32 citations Open access
Semantic Scholar
Prevalence of the Hippo Effectors YAP1/TAZ in Tumors of Soft Tissue and Bone
I. Isfort, S. Elges, M. Cyra, Ruth Berthold +15 more
2019Scientific Reports32 citations Open access
Semantic Scholar
Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies
I. Kyriakidis, Eleni Vasileiou, C. Rossig, E. Roilides +2 more
2021Journal of Fungi31 citations Open access
Semantic Scholar
Comprehensive assessments and related interventions to enhance the long-term outcomes of child, adolescent and young adult cancer survivors – presentation of the CARE for CAYA-Program study protocol and associated literature review
J. Salchow, Julia Mann, B. Koch, J. von Grundherr +30 more
2020BMC Cancer31 citations Open access
Semantic Scholar
Requirement for YAP1 signaling in myxoid liposarcoma
M. Trautmann, Ya-Yun Cheng, Patrizia Jensen, N. Azoitei +20 more
2019EMBO Molecular Medicine31 citations Open access
Semantic Scholar
Single-agent expansion cohort of lenvatinib (LEN) and combination dose-finding cohort of LEN + etoposide (ETP) + ifosfamide (IFM) in patients (pts) aged 2 to ≤25 years with relapsed/refractory osteosarcoma (OS).
N. Gaspar, M. Casanova, F. Sirvent, R. Venkatramani +16 more
201830 citations
Semantic Scholar
Targeted siRNA nanocarrier: a platform technology for cancer treatment
N. Bäumer, Jessica Tiemann, Annika Scheller, T. Meyer +18 more
2022Oncogene28 citations Open access
Semantic Scholar
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
M. Graf, M. Interlandi, N. Moreno, D. Holdhof +20 more
2022Nature Communications25 citations Open access
Semantic Scholar
Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia
M. Stanulla, E. Schaeffeler, A. Möricke, S. Buchmann +23 more
2021Leukemia25 citations Open access
Semantic Scholar
Electrostatic anti-CD33-antibody–protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia
N. Bäumer, Annika Scheller, Lisa Wittmann, A. Faust +23 more
2022Journal of Hematology & Oncology23 citations Open access
Semantic Scholar
Generation of an NFκB-Driven Alpharetroviral “All-in-One” Vector Construct as a Potent Tool for CAR NK Cell Therapy
L. Rudek, Katharina Zimmermann, Melanie Galla, Johann Meyer +12 more
2021Frontiers in Immunology20 citations Open access
Semantic Scholar
A Protochlorophyllide (Pchlide) a Oxygenase for Plant Viability
S. Reinbothe, Sandra Bartsch, C. Rossig, Manli Y. Davis +3 more
2019Frontiers in Plant Science20 citations Open access
Semantic Scholar
Inotuzumab ozogamicin combined with chemotherapy in pediatric B-cell precursor CD22+ acute lymphoblastic leukemia: results of the phase IB ITCC-059 trial
E. Pennesi, E. Brivio, A. Ammerlaan, Yi-Li Jiang +18 more
2024Haematologica19 citations Open access
Semantic Scholar
Epidemiology and management burden of invasive fungal infections after autologous hematopoietic stem cell transplantation: 10‐year experience at a European Pediatric Cancer Center
C. Linke, A. Tragiannidis, M. Ahlmann, B. Fröhlich +4 more
2019Mycoses (Berlin)19 citations Open access
Semantic Scholar
Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C
Andrej Paluda, A. Middleton, C. Rossig, P. Mace +1 more
2022Nature Communications18 citations Open access
Semantic Scholar
HLA-G and HLA-E Immune Checkpoints Are Widely Expressed in Ewing Sarcoma but Have Limited Functional Impact on the Effector Functions of Antigen-Specific CAR T Cells
B. Altvater, S. Kailayangiri, Lina F. Pérez Lanuza, K. Urban +8 more
2021Cancers18 citations Open access
Semantic Scholar
Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS)
M. Scheer, B. Blank, S. Bauer, C. Vokuhl +22 more
2020Journal of Cancer Research and Clinical Oncology18 citations Open access
Semantic Scholar
Osteosarcoma and causes of death: A report of 1520 deceased patients from the Cooperative Osteosarcoma Study Group (COSS).
S. Bielack, C. Blattmann, A. Borkhardt, M. Csóka +17 more
2022European Journal of Cancer17 citations Open access
Semantic Scholar
Impact of COVID-19 in paediatric early-phase cancer clinical trials in Europe: A report from the Innovative Therapies for Children with Cancer (ITCC) consortium
A. Rubio-San-Simón, N. André, M. Cefalo, I. Aerts +33 more
2020European Journal of Cancer17 citations Open access
Semantic Scholar
Anti-CD19 CARs displayed at the surface of lentiviral vector particles promote transduction of target-expressing cells
N. Cordes, C. Kolbe, Dominik Lock, T. Holzer +12 more
2021Molecular Therapy: Methods & Clinical Development16 citations Open access
Semantic Scholar
SIRPα-specific monoclonal antibody enables antibody-dependent phagocytosis of neuroblastoma cells
Meriem Bahri, S. Kailayangiri, S. Vermeulen, Natacha Galopin +4 more
2021Cancer Immunology and Immunotherapy15 citations Open access
Semantic Scholar
Titratable Pharmacological Regulation of CAR T Cells Using Zinc Finger-Based Transcription Factors
Bettina Kotter, F. Engert, W. Krueger, Andre Roy +13 more
2021Cancers14 citations Open access
Semantic Scholar
Low incidence of symptomatic osteonecrosis after allogeneic HSCT in children with high‐risk or relapsed ALL – results of the ALL‐SCT 2003 trial
M. Kuhlen, P. Bader, M. Sauer, M. Albert +23 more
2018British Journal of Haematology14 citations Open access
Semantic Scholar
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process
B. Altvater, S. Kailayangiri, Christian Spurny, Maike Flügge +15 more
2023Cancer Gene Therapy13 citations Open access
Semantic Scholar
Parvovirus B19 infection in pediatric allogeneic hematopoietic cell transplantation – Single‐center experience and review
Malcolm Holterhus, M. Hennies, H. Hillmann, Heike Thorer +3 more
2023Transplant Infectious Disease13 citations Open access
Semantic Scholar
Surface expression of the immunotherapeutic target GD2 in osteosarcoma depends on cell confluency
Malena Wiebel, S. Kailayangiri, B. Altvater, J. Meltzer +3 more
2021Cancer Reports13 citations Open access
Semantic Scholar
Variable Expression of the Disialoganglioside GD2 in Breast Cancer Molecular Subtypes
R. Erber, S. Kailayangiri, Hanna Huebner, M. Ruebner +13 more
2021Cancers13 citations Open access
Semantic Scholar
Phase I combination dose-finding/phase II expansion cohorts of lenvatinib + etoposide + ifosfamide in patients (pts) aged 2 to ≤ 25 years with relapsed/refractory (r/r) osteosarcoma
N. Gaspar, F. B. Bautista Sirvent, R. Venkatramani, A. Longhi +16 more
2019Annals of Oncology13 citations Open access
Semantic Scholar
Using stroma-anchoring cytokines to augment ADCC: a phase 1 trial of F16IL2 and BI 836858 for posttransplant AML relapse
A. Berdel, L. Ruhnke, L. Angenendt, M. Wermke +20 more
2022Blood Advances12 citations Open access
Semantic Scholar

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