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K. Keller · SciRah

Researcher profile · Semantic Scholar

K. Keller

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K. Keller — researcher profile on SciRah

h-index: 10
Works: 17
Citations: 457

Most-cited papers

Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy
J. Wienke, L. Visser, Waleed M. Kholosy, K. Keller +44 more
2022bioRxiv116 citations Open access
Semantic Scholar
Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Gerda Kildisiute, Waleed M. Kholosy, Matthew D. Young, Kenny Roberts +35 more
2021Science Advances98 citations Open access
Semantic Scholar
Tumor to normal single cell mRNA comparisons reveal a pan-neuroblastoma cancer cell
Gerda Kildisiute, Waleed M. Kholosy, Matthew D. Young, Kenny Roberts +35 more
2020bioRxiv87 citations Open access
Semantic Scholar
RRM2 enhances MYCN-driven neuroblastoma formation and acts as a synergistic target with CHK1 inhibition
C. Nunes, L. Depestel, Liselot M. Mus, K. Keller +38 more
2022Science Advances40 citations Open access
Semantic Scholar
Anti-GD2 IgA kills tumors by neutrophils without antibody-associated pain in the preclinical treatment of high-risk neuroblastoma
Mitchell Evers, Marjolein C. Stip, K. Keller, H. Willemen +9 more
2021Journal for ImmunoTherapy of Cancer25 citations Open access
Semantic Scholar
Target Actionability Review: a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies.
K. Keller, Sonja Krausert, Apurva Gopisetty, Daniel Luedtke +13 more
2021European Journal of Cancer18 citations Open access
Semantic Scholar
Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine
K. Langenberg, S. V. van Hooff, B. Koopmans, Josephine G. M. Strijker +35 more
2025European Journal of Cancer14 citations Open access
Semantic Scholar
The potential of PARP as a therapeutic target across pediatric solid malignancies
K. Keller, J. Koetsier, L. Schild, V. Amo-Addae +13 more
2023BMC Cancer14 citations Open access
Semantic Scholar
Decrease in phospho-PRAS40 plays a role in the synergy between erlotinib and crizotinib in an EGFR and cMET wild-type squamous non-small cell lung cancer cell line.
N. Van Der Steen, A. Leonetti, K. Keller, H. Dekker +8 more
2019Biochemical Pharmacology13 citations
Semantic Scholar
Combined targeting of the p53 and pRb pathway in neuroblastoma does not lead to synergistic responses.
Nil A. Schubert, L. Schild, Stijn van Oirschot, K. Keller +6 more
2020European Journal of Cancer12 citations Open access
Semantic Scholar
Chromosome 11q loss and MYCN amplification demonstrate synthetic lethality with checkpoint kinase 1 inhibition in neuroblastoma
K. Keller, T. F. Eleveld, L. Schild, Kim van den Handel +11 more
2022Frontiers in Oncology10 citations Open access
Semantic Scholar
Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function
N. Van Der Steen, K. Keller, H. Dekker, L. Porcelli +11 more
2020Journal of Cellular Physiology6 citations Open access
Semantic Scholar
RRM2 is a target for synthetic lethal interactions with replication stress checkpoint addiction in high-risk neuroblastoma
C. Nunes, L. Depestel, Liselot M. Mus, K. Keller +30 more
2020bioRxiv4 citations Open access
Semantic Scholar
Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics
C. Hochheuser, Arjan Boltjes, K. Keller, S. Tol +9 more
2024bioRxiv1 citations Open access
Semantic Scholar
Single-cell study of bone marrow metastases reveals heterogeneity in copy number variation with paired primary tumor
C. Hochheuser, A. Boltjes, K. Keller, S. Tol +9 more
2026EJC Paediatric Oncology0 citations Open access
Semantic Scholar
Abstract A49: Combined targeting of the p53 and pRb pathway in neuroblastoma
Nil A. Schubert, L. Schild, Stijn van Oirschot, K. Keller +6 more
20200 citations
Semantic Scholar
Towards Targeted Treatment for Pediatric Cancer
K. Keller
0 citations Open access
Semantic Scholar

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