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J. Willoughby · SciRah

Researcher profile · Semantic Scholar

J. Willoughby

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J. Willoughby — researcher profile on SciRah

h-index: 13
Works: 22
Citations: 912

Most-cited papers

Conformation of the Human Immunoglobulin G2 Hinge Imparts Superagonistic Properties to Immunostimulatory Anticancer Antibodies
A. White, H. Claude Chan, R. French, J. Willoughby +14 more
2015Cancer Cell162 citations Open access
Semantic Scholar
Antibodies to Costimulatory Receptor 4‐1BB Enhance Anti‐tumor Immunity via T Regulatory Cell Depletion and Promotion of CD8 T Cell Effector Function
Sarah L. Buchan, L. Dou, M. Remer, S. Booth +25 more
2018Immunity145 citations Open access
Semantic Scholar
OX40: Structure and function - What questions remain?
J. Willoughby, J. Griffiths, I. Tews, M. Cragg
2017Molecular Immunology125 citations Open access
Semantic Scholar
Sustained TL1A expression modulates effector and regulatory T-cell responses and drives intestinal goblet cell hyperplasia
V. Taraban, T. Ślebioda, J. Willoughby, Sarah L. Buchan +6 more
2010Mucosal Immunology104 citations Open access
Semantic Scholar
Triggering of TNFRSF25 promotes CD8+ T‐cell responses and anti‐tumor immunity
Tomasz J. Slebioda, Tania F. Rowley, J. Ferdinand, J. Willoughby +3 more
2011European Journal of Immunology60 citations Open access
Semantic Scholar
Differential Impact of CD27 and 4-1BB Costimulation on Effector and Memory CD8 T Cell Generation following Peptide Immunization
J. Willoughby, J. Kerr, A. Rogel, V. Taraban +3 more
2014Journal of Immunology55 citations Open access
Semantic Scholar
Akt signaling is critical for memory CD8+ T-cell development and tumor immune surveillance
A. Rogel, J. Willoughby, Sarah L. Buchan, H. Leonard +2 more
2017Proceedings of the National Academy of Sciences of the United States of America53 citations Open access
Semantic Scholar
Fc-null anti-PD-1 monoclonal antibodies deliver optimal checkpoint blockade in diverse immune environments
Julia Moreno-Vicente, J. Willoughby, M. Taylor, S. Booth +10 more
2022Journal for ImmunoTherapy of Cancer42 citations Open access
Semantic Scholar
Augmentation of CD134 (OX40)-dependent NK anti-tumour activity is dependent on antibody cross-linking
A. Turaj, K. Cox, Christine A. Penfold, R. French +9 more
2018Scientific Reports40 citations Open access
Semantic Scholar
Thymocyte Development but Not Net, Are Functionally Equivalent in Ternary Complex Factors SAP-1 and Elk-1,
P. Costello, R. Nicolas, J. Willoughby, B. Wasylyk +2 more
201038 citations
Semantic Scholar
CD27 costimulation contributes substantially to the expansion of functional memory CD8+ T cells after peptide immunization
Vadim Y. Taraban, Tania F. Rowley, J. Kerr, J. Willoughby +3 more
2013European Journal of Immunology30 citations
Semantic Scholar
Domain binding and isotype dictate the activity of anti-human OX40 antibodies
J. Griffiths, Khiyam Hussain, Hannah L. Smith, T. Sanders +17 more
2020Journal for ImmunoTherapy of Cancer24 citations Open access
Semantic Scholar
Raf signalling but not the ERK effector SAP-1 is required for regulatory T cell development
J. Willoughby, P. Costello, R. Nicolas, Nicholas J. Robinson +3 more
2007Journal of Immunology19 citations Open access
Semantic Scholar
Impact of isotype on the mechanism of action of agonist anti-OX40 antibodies in cancer: implications for therapeutic combinations
J. Willoughby, L. Dou, S. Bhattacharya, H. Jackson +28 more
2024Journal for ImmunoTherapy of Cancer8 citations Open access
Semantic Scholar
Preclinical evaluation of a non-depleting, first-in-class humanized IgG4 agonist anti-ICOS antibody.
S. Brett, S. Yadavilli, L. Seestaller-Wehr, S. Bhattacharya +16 more
2018Annals of Oncology5 citations Open access
Semantic Scholar
Abstract IA03: Optimizing immunostimulatory antibodies for cancer immunotherapy
Xiao-Jie Yu, Anne White, M. Glennie, I. Tews +9 more
2020Oral Presentations - Invited Abstracts0 citations
Semantic Scholar
Abstract B055: Augmentation of OX40-dependent NK mediated antitumor activity is dependent on antibody cross-linking
S. Lim, A. Turaj, J. Willoughby, C. Chan +5 more
20160 citations
Semantic Scholar
Abstract IA22: Targeting inducible T cell co-stimulator (ICOS) promotes effector T cell function and antitumor response
P. Mayes, S. Yadavilli, Yao-bin Liu, M. Bi +17 more
20160 citations
Semantic Scholar
ImmunizationT Cell Generation following Peptide Costimulation on Effector and Memory CD8 Differential Impact of CD27 and 4-1BB
A. Al-Shamkhani, Y. Taraban, Sarah L. Buchan, P. Johnson +3 more
20140 citations
Semantic Scholar
Generation following Peptide Costimulation on Effector and Memory CD 8 Differential Impact of CD 27 and 4-1 BB
A. Al-Shamkhani, Y. Taraban, Sarah L. Buchan, P. Johnson +4 more
20140 citations
Semantic Scholar
This information is current as Thymocyte Development but Not Net , Are Functionally Equivalent in Ternary Complex Factors SAP-1 and Elk
P. Costello, R. Nicolas, J. Willoughby, B. Wasylyk +2 more
20100 citations
Semantic Scholar
The role of ternary complex factors in T cell development and function
J. Willoughby
20080 citations
Semantic Scholar

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J. Griffiths — researcher profile on SciRah