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Alejandro Castellanos-González · SciRah

Researcher profile · Semantic Scholar

Alejandro Castellanos-González

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Alejandro Castellanos-González — researcher profile on SciRah

h-index: 24
Works: 57
Citations: 1,634

Most-cited papers

Multiplexed Recombinase Polymerase Amplification Assay To Detect Intestinal Protozoa.
Z. Crannell, Alejandro Castellanos-González, G. Nair, Rojelio Mejia +2 more
2016Analytical Chemistry147 citations Open access
Semantic Scholar
Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii
Ryan C. Murphy, K. Ojo, E. T. Larson, Alejandro Castellanos-González +10 more
2010ACS Medicinal Chemistry Letters138 citations Open access
Semantic Scholar
Treatment of Cryptosporidium: What We Know, Gaps, and the Way Forward
Hayley Sparks, G. Nair, Alejandro Castellanos-González, A. C. White
2015Current Tropical Medicine Reports129 citations Open access
Semantic Scholar
Intestinal Immune Response to Human Cryptosporidium sp. Infection
Birte Pantenburg, Sara M. Dann, H. Wang, P. Robinson +3 more
2007Infection and Immunity86 citations Open access
Semantic Scholar
A novel calcium-dependent protein kinase inhibitor as a lead compound for treating cryptosporidiosis.
Alejandro Castellanos-González, A. White, K. Ojo, R. Vidadala +10 more
2013Journal of Infectious Diseases76 citations Open access
Semantic Scholar
Nucleic Acid Test to Diagnose Cryptosporidiosis: Lab Assessment in Animal and Patient Specimens
Z. Crannell, Alejandro Castellanos-González, A. Irani, B. Rohrman +2 more
2014Analytical Chemistry74 citations Open access
Semantic Scholar
Human Primary Intestinal Epithelial Cells as an Improved In Vitro Model for Cryptosporidium parvum Infection
Alejandro Castellanos-González, M. Cabada, J. Nichols, G. Gómez +1 more
2013Infection and Immunity64 citations Open access
Semantic Scholar
Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy
Matthew A. Hulverson, S. Vinayak, Ryan Choi, Deborah A. Schaefer +16 more
2017Journal of Infectious Diseases61 citations Open access
Semantic Scholar
Recombinase polymerase amplification-based assay to diagnose Giardia in stool samples.
Z. Crannell, M. Cabada, Alejandro Castellanos-González, A. Irani +2 more
2015American Journal of Tropical Medicine and Hygiene55 citations Open access
Semantic Scholar
An Innovative Field-Applicable Molecular Test to Diagnose Cutaneous Leishmania Viannia spp. Infections
Omar A. Saldarriaga, Alejandro Castellanos-González, R. Porrozzi, G. C. Baldeviano +7 more
2016PLoS Neglected Tropical Diseases49 citations Open access
Semantic Scholar
Cryptosporidium infection of human intestinal epithelial cells increases expression of osteoprotegerin: a novel mechanism for evasion of host defenses.
Alejandro Castellanos-González, Linda S. Yancey, H. Wang, Birte Pantenburg +3 more
2008Journal of Infectious Diseases49 citations
Semantic Scholar
Recombinase Polymerase Amplification Compared to Real-Time Polymerase Chain Reaction Test for the Detection of Fasciola hepatica in Human Stool.
M. Cabada, J. Malaga, Alejandro Castellanos-González, Kelli A. Bagwell +5 more
2017American Journal of Tropical Medicine and Hygiene48 citations Open access
Semantic Scholar
Benzoylbenzimidazole-based selective inhibitors targeting Cryptosporidium parvum and Toxoplasma gondii calcium-dependent protein kinase-1
Zhongsheng Zhang, K. Ojo, Steven M. Johnson, E. T. Larson +10 more
2012Bioorganic & Medicinal Chemistry Letters47 citations Open access
Semantic Scholar
Human CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells.
Birte Pantenburg, Alejandro Castellanos-González, Sara M. Dann, R. Connelly +3 more
2010American Journal of Tropical Medicine and Hygiene46 citations Open access
Semantic Scholar
Isothermal recombinase polymerase amplification-lateral flow detection of SARS-CoV-2, the etiological agent of COVID-19
Thomas R. Shelite, A. Uscanga-Palomeque, Alejandro Castellanos-González, P. Melby +1 more
2020Journal of Virological Methods45 citations Open access
Semantic Scholar
Detection of Entamoeba histolytica by Recombinase Polymerase Amplification.
G. Nair, Mauricio Rebolledo, A. White, Z. Crannell +5 more
2015American Journal of Tropical Medicine and Hygiene43 citations Open access
Semantic Scholar
Seropositive human subjects produce interferon gamma after stimulation with recombinant Cryptosporidium hominis gp15.
Geoffrey A. Preidis, H. Wang, D. Lewis, Alejandro Castellanos-González +4 more
2007American Journal of Tropical Medicine and Hygiene41 citations Open access
Semantic Scholar
Molecular diagnosis of protozoan parasites by Recombinase Polymerase Amplification
Alejandro Castellanos-González, A. White, Peter C. Melby, B. Travi
2018Acta Tropica40 citations Open access
Semantic Scholar
Oligonucleotide-Gold Nanoparticle Networks for Detection of Cryptosporidium parvum Heat Shock Protein 70 mRNA
David J. Javier, Alejandro Castellanos-González, Shannon Weigum, A. White +1 more
2009Journal of Clinical Microbiology40 citations Open access
Semantic Scholar
A Novel Molecular Test to Diagnose Canine Visceral Leishmaniasis at the Point of Care.
Alejandro Castellanos-González, Omar A. Saldarriaga, Lilian Tartaglino, Rosana Gacek +4 more
2015American Journal of Tropical Medicine and Hygiene36 citations Open access
Semantic Scholar
A Novel Calcium-Dependent Kinase Inhibitor, Bumped Kinase Inhibitor 1517, Cures Cryptosporidiosis in Immunosuppressed Mice.
Alejandro Castellanos-González, Hayley Sparks, S. Nava, Wenlin Huang +8 more
2016Journal of Infectious Diseases34 citations Open access
Semantic Scholar
Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis Thymidylate Synthase-Dihydrofolate Reductase
V. P. Kumar, J. A. Cisneros, K. Frey, Alejandro Castellanos-González +5 more
2014Bioorganic & Medicinal Chemistry Letters34 citations Open access
Semantic Scholar
Efficacy of Recombinase Polymerase Amplification to Diagnose Trypanosoma cruzi Infection in Dogs with Cardiac Alterations from an Endemic Area of Mexico
M. Jiménez-Coello, Thomas R. Shelite, Alejandro Castellanos-González, Omar A. Saldarriaga +7 more
2018Vector Borne and Zoonotic Diseases32 citations
Semantic Scholar
Preassembled Single-Stranded RNA-Argonaute Complexes: A Novel Method to Silence Genes in Cryptosporidium.
Alejandro Castellanos-González, Nicolas Perry, S. Nava, A. White
2015Journal of Infectious Diseases28 citations Open access
Semantic Scholar
Cloning, production and characterisation of a recombinant Cu/Zn superoxide dismutase from Taenia solium.
Alejandro Castellanos-González, L. Jiménez, A. Landa
2002International Journal of Parasitology24 citations
Semantic Scholar
Treatable bacterial infections are underrecognized causes of fever in Ethiopian children.
Sara J. Aarsland, Alejandro Castellanos-González, Kameron P. Lockamy, Ruth Mulu-Droppers +3 more
2012American Journal of Tropical Medicine and Hygiene19 citations Open access
Semantic Scholar
Novel drug targets for treatment of cryptosporidiosis
Bei-Lin Wang, Alejandro Castellanos-González, A. C. White
2020Expert opinion on therapeutic targets17 citations
Semantic Scholar
Diagnostic Efficacy of Recombinase-Polymerase-Amplification Coupled with Lateral Flow Strip Reading in Patients with Cutaneous Leishmaniasis from the Amazonas Rainforest of Perú
B. Travi, M. B. De Los Santos, Thomas R. Shelite, R. Santos +4 more
2021Vector Borne and Zoonotic Diseases16 citations
Semantic Scholar
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium
A. Mukerjee, P. Iyidogan, Alejandro Castellanos-González, J. A. Cisneros +6 more
2015Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Direct RT-PCR ampli�cation of SARS-CoV-2 from clinical samples using a concentrated viral Lysis-Ampli�cation Buffer prepared with IGEPAL-630.
Alejandro Castellanos-González, Thomas R. Shelite
202015 citations
Semantic Scholar
Systematic gene silencing identified Cryptosporidium nucleoside diphosphate kinase and other molecules as targets for suppression of parasite proliferation in human intestinal cells
Alejandro Castellanos-González, G. Martinez-Traverso, K. Fishbeck, S. Nava +1 more
2019Scientific Reports13 citations Open access
Semantic Scholar
Killing of Cryptosporidium sporozoites by Lactoferrin.
J. Paredes, Hayley Sparks, A. White, G. Martinez-Traverso +2 more
2017American Journal of Tropical Medicine and Hygiene13 citations Open access
Semantic Scholar
A Novel Method to Silence Genes in Cryptosporidium
Alejandro Castellanos-González
2019Methods in molecular biology10 citations
Semantic Scholar
Cryptosporidium parvum Subtilisin-Like Serine Protease (SUB1) Is Crucial for Parasite Egress from Host Cells
S. Nava, A. White, Alejandro Castellanos-González
2019Infection and Immunity9 citations Open access
Semantic Scholar
Amplification-Free Detection of Cryptosporidium parvum Nucleic Acids Using DNA/RNA-Directed Gold Nanoparticle Assemblies
Shannon Weigum, Alejandro Castellanos-González, A. White, Rebecca Richards-Kortum
2013Journal of Parasitology9 citations Open access
Semantic Scholar
Cryptosporidium parvum cyclic GMP-dependent protein kinase (PKG): An essential mediator of merozoite egress
S. Nava, Aygul Sadiqova, Alejandro Castellanos-González, A. White
2020Molecular and biochemical parasitology (Print)8 citations Open access
Semantic Scholar
The Recombinase Polymerase Amplification Test for Strongyloides stercoralis Is More Sensitive than Microscopy and Real-Time PCR in High-Risk Communities of Cusco, Peru
J. Malaga, Martha V. Fernández-Baca, Alejandro Castellanos-González, Melinda B. Tanabe +6 more
2024Pathogens7 citations Open access
Semantic Scholar
Fasciola hepatica Infection in an Indigenous Community of the Peruvian Jungle.
M. Cabada, Alejandro Castellanos-González, Martha Lopez, M. A. Caravedo +2 more
2016American Journal of Tropical Medicine and Hygiene6 citations Open access
Semantic Scholar
Identification and functional characterization of the siRNA pathway in Taenia crassiceps by silencing Enolase A.
Julio Guerrero-Hernández, R. Bobes, M. García-Varela, Alejandro Castellanos-González +1 more
2021Acta Tropica4 citations Open access
Semantic Scholar
A PCR Test Using the Mini-PCR Platform and Simplified Product Detection Methods Is Highly Sensitive and Specific to Detect Fasciola hepatica DNA Mixed in Human Stool, Snail Tissue, and Water DNA Specimens
Martha V. Fernández-Baca, Alejandro Castellanos-González, Rodrigo A. Ore, Jose L. Alccacontor-Muñoz +7 more
2024Pathogens3 citations Open access
Semantic Scholar
MiniPCR as a Portable Equipment for the Molecular Diagnosis of American Cutaneous Leishmaniasis.
Alejandro Castellanos-González, Alexandra Cossio, Jimena Jojoa, Scott T. Moen +1 more
2023Acta Tropica3 citations Open access
Semantic Scholar
RNA-Based Therapy for Cryptosporidium parvum Infection: Proof-of-Concept Studies
Alejandro Castellanos-González, Aygul Sadiqova, Justine Ortega-Méndez, A. White
2022bioRxiv3 citations Open access
Semantic Scholar
Seroprevalence of Naegleria fowleri in the Houston–Galveston Texas Population
Juan U. Rojo, Rajkumar Rajendran, Emmanuel M Nyangau, Alejandro Castellanos-González +1 more
2024Parasitology Research1 citations
Semantic Scholar
Oligonucleotide-gold nanoparticle networks for 1 detection of Cryptosporidium parvum HSP 70 mRNA
David J. Javier, Alejandro Castellanos-González, E. Shannon, Weigum +2 more
20091 citations
Semantic Scholar
Spatial analysis of sheep fascioliasis in rural communities of the Southern highlands of Peru
Melinda B. Tanabe, M. Morales, Beltran Jalanocca-Janampa, Cristian Hoban +19 more
2026BMC Veterinary Research0 citations Open access
Semantic Scholar
Induction of β-Defensin 1 (DEFB1) via synthetic mRNA reduces Cryptosporidium parvum infection in human intestinal cells.
Justine Ortega-Méndez, José M Rojas, A. C. White, Alejandro Castellanos-González
2026Journal of Infectious Diseases0 citations
Semantic Scholar
Frequency, Geospatial Distribution, and Subspecies of Echinococcus Granulosus Identified in Dog Stool in Urban Public Spaces of an Endemic Area in Cusco, Peru.
M. Cabada, R. Pineda-Reyes, Nelson Lozano-Cansaya, Beltran Jalanocca-Janampa +11 more
2026American Journal of Tropical Medicine and Hygiene0 citations Open access
Semantic Scholar
A Novel Method to Silence Genes in Cryptosporidium.
Alejandro Castellanos-González
2026Methods in molecular biology0 citations
Semantic Scholar
Rationale for a live-attenuated vaccine for cryptosporidiosis.
A. C. White, S. M. Dann, Alejandro Castellanos-González
2026Journal of Infectious Diseases0 citations
Semantic Scholar
Prodrug nanotherapy demonstrates in vivo anticryptosporidial efficacy in a mouse model of chronic Cryptosporidium infection
A. Ranjan, D. Czyzyk, G. Martinez-Traverso, Aygul Sadiqova +8 more
2024RSC pharmaceutics0 citations Open access
Semantic Scholar

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