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R. Vidadala · SciRah

Researcher profile · Semantic Scholar

R. Vidadala

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R. Vidadala — researcher profile on SciRah

h-index: 17
Works: 36
Citations: 1,071

Most-cited papers

Development of an Orally Available and Central Nervous System (CNS)-Penetrant Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) Inhibitor with Minimal Human Ether-à-go-go-Related Gene (hERG) Activity for the Treatment of Toxoplasmosis
R. Vidadala, Kasey L. Rivas, K. Ojo, Matthew A. Hulverson +22 more
2016Journal of Medicinal Chemistry93 citations Open access
Semantic Scholar
A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.
K. Ojo, Richard T. Eastman, R. Vidadala, Zhongsheng Zhang +17 more
2014Journal of Infectious Diseases93 citations Open access
Semantic Scholar
A novel calcium-dependent protein kinase inhibitor as a lead compound for treating cryptosporidiosis.
Alejandro Castellanos-González, A. White, K. Ojo, R. Vidadala +10 more
2013Journal of Infectious Diseases76 citations Open access
Semantic Scholar
Neospora caninum Calcium-Dependent Protein Kinase 1 Is an Effective Drug Target for Neosporosis Therapy
K. Ojo, Molly C. Reid, Latha Kallur Siddaramaiah, Joachim Müller +10 more
2014PLoS ONE73 citations Open access
Semantic Scholar
Novel Bumped Kinase Inhibitors Are Safe and Effective Therapeutics in the Calf Clinical Model for Cryptosporidiosis.
Deborah A. Schaefer, Dana P. Betzer, Kylie D Smith, Zachary G Millman +14 more
2016Journal of Infectious Diseases71 citations Open access
Semantic Scholar
Bumped-Kinase Inhibitors for Cryptosporidiosis Therapy
Matthew A. Hulverson, S. Vinayak, Ryan Choi, Deborah A. Schaefer +16 more
2017Journal of Infectious Diseases61 citations Open access
Semantic Scholar
Development of Potent and Selective Plasmodium falciparum Calcium-Dependent Protein Kinase 4 (PfCDPK4) Inhibitors that Block the Transmission of Malaria to Mosquitoes
R. Vidadala, K. Ojo, Steven M. Johnson, Zhongsheng Zhang +15 more
2014European journal of medicinal chemistry59 citations Open access
Semantic Scholar
Potent and selective inhibitors of CDPK1 from T. gondii and C. parvum based on a 5-aminopyrazole-4-carboxamide scaffold
Zhongsheng Zhang, K. Ojo, R. Vidadala, Wenlin Huang +18 more
2013ACS Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
An integrated approach reveals a regulatory mechanism coupling Src’s kinase activity, localization, and phosphotransferase-independent functions
Ethan Ahler, A. Register, Sujata Chakraborty, L. Fang +11 more
2019Molecules and Cells53 citations Open access
Semantic Scholar
The Gatekeeper Residue and Beyond
K. Keyloun, Molly C. Reid, Ryan Choi, Yifan Song +11 more
2014Parasitology53 citations Open access
Semantic Scholar
Bumped Kinase Inhibitors as therapy for apicomplexan parasitic diseases: lessons learned
Ryan Choi, Matthew A. Hulverson, Wenlin Huang, R. Vidadala +22 more
2020International Journal of Parasitology47 citations Open access
Semantic Scholar
Necessity of Bumped Kinase Inhibitor Gastrointestinal Exposure in Treating Cryptosporidium Infection
Samuel L. M. Arnold, Ryan Choi, Matthew A. Hulverson, Deborah A. Schaefer +12 more
2017Journal of Infectious Diseases46 citations Open access
Semantic Scholar
Kinobead and single-shot LC-MS profiling identifies selective PKD inhibitors
Martin G. Golkowski, R. Vidadala, Chloe K. Lombard, Hyong Won Suh +2 more
2017Journal of Proteome Research41 citations Open access
Semantic Scholar
SAR Studies of 5-Aminopyrazole-4-carboxamide Analogues as Potent and Selective Inhibitors of Toxoplasma gondii CDPK1
Wenlin Huang, K. Ojo, Zhongsheng Zhang, Kasey L. Rivas +22 more
2015ACS Medicinal Chemistry Letters40 citations Open access
Semantic Scholar
Advances in bumped kinase inhibitors for human and animal therapy for cryptosporidiosis
Matthew A. Hulverson, Ryan Choi, Samuel L. M. Arnold, Deborah A. Schaefer +22 more
2017International Journal of Parasitology31 citations Open access
Semantic Scholar
One Health Therapeutics: Target-Based Drug Development for Cryptosporidiosis and Other Apicomplexa Diseases
W. Van Voorhis, Matthew A. Hulverson, Ryan Choi, Wenlin Huang +22 more
2020Veterinary parasitology23 citations Open access
Semantic Scholar
Bumped kinase inhibitor prohibits egression in Babesia bovis
M. Pedroni, R. Vidadala, Ryan Choi, K. Keyloun +7 more
2015Veterinary parasitology21 citations Open access
Semantic Scholar
Comparative assessment of the effects of bumped kinase inhibitors on early zebrafish embryo development and pregnancy in mice.
N. Anghel, Pablo A. Winzer, D. Imhof, Joachim Müller +14 more
2020bioRxiv17 citations Open access
Semantic Scholar
Toxoplasma Calcium-Dependent Protein Kinase 1 Inhibitors: Probing Activity and Resistance Using Cellular Thermal Shift Assays
S. Scheele, J. Geiger, A. DeRocher, Ryan Choi +9 more
2018Antimicrobial Agents and Chemotherapy17 citations Open access
Semantic Scholar
Bumped kinase inhibitor 1369 is effective against Cystoisospora suis in vivo and in vitro
Aruna Shrestha, K. Ojo, Florian Koston, B. Ruttkowski +13 more
2019International Journal for Parasitology: Drugs and Drug Resistance16 citations Open access
Semantic Scholar
Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis.
Matthew A. Hulverson, I. Bruzual, Erin V. McConnell, Wenlin Huang +15 more
2018Journal of Infectious Diseases16 citations Open access
Semantic Scholar
5-Aminopyrazole-4-Carboxamide-Based Compounds Prevent the Growth of Cryptosporidium parvum
Wenlin Huang, Ryan Choi, Matthew A. Hulverson, Zhongsheng Zhang +10 more
2017Antimicrobial Agents and Chemotherapy16 citations Open access
Semantic Scholar
Pyrrolopyrimidine Bumped Kinase Inhibitors for Treatment of Cryptosporidiosis
Matthew A. Hulverson, Ryan Choi, R. Vidadala, G. R. Whitman +8 more
2021ACS Infectious Diseases13 citations Open access
Semantic Scholar
P-Glycoprotein–Mediated Efflux Reduces the In Vivo Efficacy of a Therapeutic Targeting the Gastrointestinal Parasite Cryptosporidium
Samuel L. M. Arnold, Ryan Choi, Matthew A. Hulverson, G. R. Whitman +9 more
2019Journal of Infectious Diseases10 citations Open access
Semantic Scholar
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
T. Uo, K. Ojo, Cynthia C. T. Sprenger, Kathryn Soriano Epilepsia +23 more
2024Molecular Cancer Therapeutics6 citations Open access
Semantic Scholar
7H-pyrrolo[2,3-d]pyrimidin-4-amine based inhibitors of calcium dependent protein kinase 1 have distinct inhibitory and oral pharmacokinetic characteristics compared with 1H-pyrazolo[3,4-d]pyrimidin-4-amine based inhibitors.
R. Vidadala, Martin G. Golkowski, Matthew A. Hulverson, Ryan Choi +10 more
2018ACS Infectious Diseases6 citations Open access
Semantic Scholar
A novel protein kinase is essential in bloodstream Trypanosoma brucei
B. Jensen, Nick Booster, R. Vidadala, Dustin J Maly +1 more
2016International Journal of Parasitology6 citations Open access
Semantic Scholar
In vitro growth inhibition of Theileria equi by bumped kinase inhibitors
Fernanda Giménez, S. Hines, Ryan M. Evanoff, K. Ojo +4 more
2018Veterinary parasitology4 citations Open access
Semantic Scholar
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer
T. Uo, K. Ojo, Cynthia C. T. Sprenger, K. Epilepsia +23 more
2023bioRxiv3 citations Open access
Semantic Scholar
Novel C-9, 9'-O-acyl esters of (-)-carinol as free-radical scavengers and xanthine oxidase enzyme inhibitors: synthesis and biological evaluation.
P. Suryadevara, H. Tatipaka, R. Vidadala, A. Tiwari +2 more
2012Medicinal chemistry2 citations
Semantic Scholar
Isolation, characterization and semi-synthesis of natural products dimeric amide alkaloids
R. Vidadala, M. J.
2021Journal of Natural Products and Natural Products Synthesis1 citations Open access
Semantic Scholar
An integrated approach reveals a regulatory mechanism coupling Src’s kinase activity, localization, and phosphotransferase-independent functions
Ethan Ahler, A. Register, Sujata Chakraborty, L. Fang +10 more
20191 citations
Semantic Scholar
Novel C-9, 9'-O-acyl Esters of (-)-Carinol as Free-radical Scavengers and Xanthine Oxidase Enzyme Inhibitors: Synthesis and Biological Evaluation
P. Suryadevara, H. Tatipaka, R. Vidadala, A. Tiwari +2 more
20121 citations
Semantic Scholar
Study and optimization of Diels-Alder reaction of piperine in aqueous ionic solutions using Gn.HCl as a catalyst
R. Vidadala
2021Journal of Green Chemistry and Chemical Engineering0 citations Open access
Semantic Scholar
Abstract 3837: Bumped kinase inhibitor 1553 selectively inhibits androgen receptor positive prostate cancer
T. Uo, Shi-Hua Sun, K. Haugk, K. Epilepsia +8 more
2018Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Speci fi c Inhibitor of Pf CDPK 4 Blocks Malaria Transmission : Chemical-genetic Validation
K. Ojo, Richard T. Eastman, R. Vidadala, Zhongsheng Zhang +17 more
20130 citations
Semantic Scholar

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