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Xin-zhuan Su · SciRah

Researcher profile · Semantic Scholar

Xin-zhuan Su

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Xin-zhuan Su — researcher profile on SciRah

h-index: 68
Works: 182
Citations: 18K

Most-cited papers

Malaria biology and disease pathogenesis: insights for new treatments
L. Miller, Hans C. Ackerman, Xin-zhuan Su, T. Wellems
2013Nature Medicine571 citations Open access
Semantic Scholar
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
M. Manske, O. Miotto, S. Campino, S. Auburn +52 more
2012Nature501 citations Open access
Semantic Scholar
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
O. Miotto, J. Almagro-Garcia, M. Manske, B. MacInnis +58 more
2013Nature Genetics471 citations Open access
Semantic Scholar
Artemisinin: Discovery from the Chinese Herbal Garden
L. Miller, Xin-zhuan Su
2011Cell421 citations Open access
Semantic Scholar
Artemisinin-resistant Plasmodium falciparum in Pursat province, western Cambodia: a parasite clearance rate study
Chanaki Amaratunga, Sokunthea Sreng, Seila Suon, Erik Phelps +16 more
2012Lancet. Infectious Diseases (Print)350 citations Open access
Semantic Scholar
Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia
Shannon Takala-Harrison, T. Clark, Christopher G. Jacob, M. P. Cummings +35 more
2012Proceedings of the National Academy of Sciences of the United States of America284 citations Open access
Semantic Scholar
Malaria in the Greater Mekong Subregion: Heterogeneity and Complexity
Li-Wang Cui, G. Yan, J. Sattabongkot, Yaming Cao +16 more
2011Acta Tropica264 citations Open access
Semantic Scholar
The discovery of artemisinin and Nobel Prize in Physiology or Medicine
Xin-zhuan Su, L. Miller
2015Science China Life Sciences257 citations Open access
Semantic Scholar
Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum
A. Miles, Z. Iqbal, P. Vauterin, R. Pearson +18 more
2016Genome Research220 citations Open access
Semantic Scholar
Bone marrow-resident NK cells prime monocytes for regulatory function during infection
Michael H. Askenase, Seong-Ji Han, A. Byrd, D. M. da Fonseca +9 more
2015Immunity218 citations Open access
Semantic Scholar
Efficient Editing of Malaria Parasite Genome Using the CRISPR/Cas9 System
Cui Zhang, Bo Xiao, Yuanyuan Jiang, Yihua Zhao +9 more
2014mBio144 citations Open access
Semantic Scholar
Chemical genomic profiling for antimalarial therapies, response signatures and molecular targets
Jing Yuan, Ken Cheng, Ronald L. Johnson, Ruili Huang +8 more
2011Science140 citations Open access
Semantic Scholar
Plasmodium falciparum Gametocyte Development 1 (Pfgdv1) and Gametocytogenesis Early Gene Identification and Commitment to Sexual Development
Saliha Ekşi, B. Morahan, Y. Haile, T. Furuya +11 more
2012PLoS Pathogens139 citations Open access
Semantic Scholar
Pf7: an open dataset of Plasmodium falciparum genome variation in 20,000 worldwide samples
M. A. Abdel Hamid, M. H. Abdelraheem, D. O. Acheampong, Ambroise D. Ahouidi +168 more
2023Wellcome Open Research138 citations Open access
Semantic Scholar
Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk
De-Liang Zhang, Jian Wu, Binal N. Shah, Katja C Greutélaers +8 more
2018Science127 citations Open access
Semantic Scholar
Cross-Regulation of Two Type I Interferon Signaling Pathways in Plasmacytoid Dendritic Cells Controls Anti-malaria Immunity and Host Mortality
Xiao Yu, Baowei Cai, Mingjun Wang, Peng Tan +9 more
2016Immunity111 citations Open access
Semantic Scholar
Mechanisms of in vitro resistance to dihydroartemisinin in Plasmodium falciparum
Long Cui, Zeng-Lei Wang, J. Miao, Miao Miao +4 more
2012Molecular Microbiology107 citations Open access
Semantic Scholar
Plasmodium Genomics and Genetics: New Insights into Malaria Pathogenesis, Drug Resistance, Epidemiology, and Evolution
Xin-zhuan Su, Kristin D. Lane, L. Xia, J. Sá +1 more
2019Clinical Microbiology Reviews106 citations Open access
Semantic Scholar
Artemisinin and its derivatives in treating protozoan infections beyond malaria
Cecilia Shi Ni Loo, Nelson Siu Kei Lam, Deying Yu, Xin-zhuan Su +1 more
2016Pharmacological Research106 citations Open access
Semantic Scholar
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations
Bryan T. Mott, Richard T. Eastman, R. Guha, Katy S. Sherlach +21 more
2015Scientific Reports104 citations Open access
Semantic Scholar
A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation.
K. Ojo, Richard T. Eastman, R. Vidadala, Zhongsheng Zhang +17 more
2014Journal of Infectious Diseases93 citations Open access
Semantic Scholar
Strain-specific innate immune signaling pathways determine malaria parasitemia dynamics and host mortality
Jian Wu, Lin-Jie Tian, Xiao Yu, Sittiporn Pattaradilokrat +15 more
2014Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Genome-wide association analysis identifies genetic loci associated with resistance to multiple antimalarials in Plasmodium falciparum from China-Myanmar border
Zeng-Lei Wang, Mynthia Cabrera, Jing-Yun Yang, Li-Li Yuan +11 more
2016Scientific Reports86 citations Open access
Semantic Scholar
Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development
Cui Zhang, Zhen-Kui Li, Huiting Cui, Yuanyuan Jiang +7 more
2017mBio82 citations Open access
Semantic Scholar
Host-Malaria Parasite Interactions and Impacts on Mutual Evolution
Xin-zhuan Su, Cui Zhang, D. Joy
2020Frontiers in Cellular and Infection Microbiology72 citations Open access
Semantic Scholar
Inflammasome activation negatively regulates MyD88-IRF7 type I IFN signaling and anti-malaria immunity
Xiao Yu, Yang Du, Chunmei Cai, Baowei Cai +10 more
2018Nature Communications64 citations Open access
Semantic Scholar
Melaleuca alternifolia (tea tree) oil and its monoterpene constituents in treating protozoan and helminthic infections.
Nelson Siu Kei Lam, X. Long, Xin-zhuan Su, Fang-Li Lu
2020Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie59 citations Open access
Semantic Scholar
Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation
J. Lemieux, S. Kyes, T. Otto, A. Feller +5 more
2013Molecular Microbiology58 citations Open access
Semantic Scholar
The roles of galectins in parasitic infections
Weikun Shi, Chun-Yu Xue, Xin-zhuan Su, Fang-Li Lu
2017Acta Tropica56 citations Open access
Semantic Scholar
Linkage maps from multiple genetic crosses and loci linked to growth-related virulent phenotype in Plasmodium yoelii
Jian Li, Sittiporn Pattaradilokrat, F. Zhu, Hong-Ying Jiang +11 more
2011Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
Challenges and prospects for malaria elimination in the Greater Mekong Subregion
Li-Wang Cui, G. Yan, J. Sattabongkot, Bin Chen +9 more
2011Acta Tropica56 citations Open access
Semantic Scholar
Population Genetic Analysis of Plasmodium falciparum Parasites Using a Customized Illumina GoldenGate Genotyping Assay
S. Campino, S. Auburn, K. Kivinen, I. Zongo +27 more
2011PLoS ONE54 citations Open access
Semantic Scholar
Large-scale Artemisinin–Piperaquine Mass Drug Administration With or Without Primaquine Dramatically Reduces Malaria in a Highly Endemic Region of Africa
Chang-Hui Deng, Bo Huang, Qi Wang, Wanting Wu +29 more
2018Clinical Infectious Diseases51 citations Open access
Semantic Scholar
Artemisinin resistance phenotypes and K13 inheritance in a Plasmodium falciparum cross and Aotus model
J. Sá, S. Kaslow, Michael A. Krause, Viviana A. Melendez-Muniz +42 more
2018Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria
Richard W Heidebrecht, Carol A. Mulrooney, C. Austin, R. Barker +27 more
2011ACS Medicinal Chemistry Letters50 citations Open access
Semantic Scholar
An intracellular membrane protein GEP1 regulates xanthurenic acid induced gametogenesis of malaria parasites
Yuanyuan Jiang, Jun Wei, Huiting Cui, Chuanyuan Liu +11 more
2020Nature Communications49 citations Open access
Semantic Scholar
Artemisinin and its derivatives in treating helminthic infections beyond schistosomiasis
Nelson Siu Kei Lam, X. Long, Xin-zhuan Su, Fang-Li Lu
2018Pharmacological Research47 citations
Semantic Scholar
CRISPR/Cas9 mediated sequential editing of genes critical for ookinete motility in Plasmodium yoelii
Cui Zhang, Han Gao, Zhen-Ke Yang, Yuanyuan Jiang +6 more
2016Molecular and biochemical parasitology (Print)46 citations Open access
Semantic Scholar
FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions
Baowei Cai, Jian Wu, Xiao Yu, Xin-zhuan Su +1 more
2017mBio44 citations Open access
Semantic Scholar
Lack of Association of the S769N Mutation in Plasmodium falciparum SERCA (PfATP6) with Resistance to Artemisinins
Long Cui, Zeng-Lei Wang, Hong-Ying Jiang, D. Parker +3 more
2012Antimicrobial Agents and Chemotherapy44 citations Open access
Semantic Scholar
Type I Interferons and Malaria: A Double-Edge Sword Against a Complex Parasitic Disease
Xiao He, L. Xia, Keyla C. Tumas, Jian Wu +1 more
2020Frontiers in Cellular and Infection Microbiology43 citations Open access
Semantic Scholar
Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature: Discovery of new antimalarial chemotypes through chemical methodology and library development
L. Brown, Ken Cheng, Wan-guo Wei, Pei-Jiang Yuan +14 more
201143 citations
Semantic Scholar
Ex Vivo Susceptibility of Plasmodium falciparum to Antimalarial Drugs in Western, Northern, and Eastern Cambodia, 2011-2012: Association with Molecular Markers
Pharath Lim, Dalin Dek, V. Try, Richard T. Eastman +16 more
2013Antimicrobial Agents and Chemotherapy42 citations Open access
Semantic Scholar
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
Xiao He, Alison W. Ashbrook, Yang Du, Jian Wu +13 more
2020Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
Polymorphisms of the artemisinin resistant marker (K13) in Plasmodium falciparum parasite populations of Grande Comore Island 10 years after artemisinin combination therapy
Bo Huang, Chang-Hui Deng, T. Yang, Linlu Xue +16 more
2015Parasites & Vectors36 citations Open access
Semantic Scholar
A Class of Tricyclic Compounds Blocking Malaria Parasite Oocyst Development and Transmission
Richard T. Eastman, Sittiporn Pattaradilokrat, D. K. Raj, S. Dixit +13 more
2012Antimicrobial Agents and Chemotherapy36 citations Open access
Semantic Scholar
Leveraging crowdsourcing to accelerate global health solutions
Sage Z Davis, Katrina A. Button-Simons, Taoufik Bensellak, Eren Ahsen +20 more
2019Nature Biotechnology33 citations
Semantic Scholar
Actinoramide A Identified as a Potent Antimalarial from Titration-based Screening of Marine Natural Product Extracts
Ken Cheng, Shu-Geng Cao, A. Raveh, R. Macarthur +13 more
2015Journal of Natural Products33 citations Open access
Semantic Scholar
'Artemisinin Resistance': Something New or Old? Something of a Misnomer?
T. Wellems, J. Sá, Xin-zhuan Su, S. Connelly +1 more
2020Trends in Parasitology32 citations
Semantic Scholar
The E3 ubiquitin ligase MARCH1 regulates antimalaria immunity through interferon signaling and T cell activation
Jian Wu, L. Xia, Xiang-Yu Yao, Xiao Yu +16 more
2020Proceedings of the National Academy of Sciences of the United States of America30 citations Open access
Semantic Scholar

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