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Hans C. Ackerman · SciRah

Researcher profile · Semantic Scholar

Hans C. Ackerman

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Hans C. Ackerman — researcher profile on SciRah

h-index: 16
Works: 50
Citations: 1,191

Most-cited papers

Malaria biology and disease pathogenesis: insights for new treatments
L. Miller, Hans C. Ackerman, Xin-zhuan Su, T. Wellems
2013Nature Medicine571 citations Open access
Semantic Scholar
Clinical Features of Severe Malaria Associated with Death: A 13-Year Observational Study in The Gambia
M. Jallow, C. Casals-Pascual, Hans C. Ackerman, B. Walther +11 more
2012PLoS ONE74 citations Open access
Semantic Scholar
Inward cholesterol gradient of the membrane system in P. falciparum-infected erythrocytes involves a dilution effect from parasite-produced lipids
F. Tokumasu, Georgeta Crivat, Hans C. Ackerman, Jeeseong Hwang +1 more
2014Biology Open47 citations Open access
Semantic Scholar
Losartan for the Nephropathy of Sickle Cell Anemia: A Phase-2, Multi-Center Trial
C. Quinn, Santosh L. Saraf, V. Gordeuk, C. Fitzhugh +14 more
2017American journal of hematology/oncology45 citations Open access
Semantic Scholar
Tempol, an Intracellular Antioxidant, Inhibits Tissue Factor Expression, Attenuates Dendritic Cell Function, and Is Partially Protective in a Murine Model of Cerebral Malaria
I. Francischetti, E. Gordon, Bruna Bizzarro, Nidhi Gera +14 more
2014PLoS ONE41 citations Open access
Semantic Scholar
Endothelial cell &agr;-globin and its molecular chaperone &agr;-hemoglobin–stabilizing protein regulate arteriolar contractility
Christophe Lechauve, Joshua T. Butcher, Abdullah Freiwan, Lauren A. Biwer +7 more
2018Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Aedes aegypti sialokinin facilitates mosquito blood feeding and modulates host immunity and vascular biology
Inés Martín-Martín, P. Valenzuela-León, L. Amo, G. Shrivastava +9 more
2022Cell Reports35 citations Open access
Semantic Scholar
Defibrotide interferes with several steps of the coagulation-inflammation cycle and exhibits therapeutic potential to treat severe malaria
I. Francischetti, C. J. Oliveira, Graciela R. Ostera, S. Yager +21 more
2011Arteriosclerosis, Thrombosis and Vascular Biology35 citations Open access
Semantic Scholar
The role of globins in cardiovascular physiology.
T. C. Steven Keller, Christophe Lechauve, Alexander S. Keller, Steven S. Brooks +5 more
2021Physiological Reviews31 citations Open access
Semantic Scholar
Endothelial alpha globin is a nitrite reductase
T. C. Stevenson Keller, Christophe Lechauve, Alexander S. Keller, G. B. Broseghini-Filho +25 more
2021bioRxiv29 citations Open access
Semantic Scholar
Decreased Rate of Plasma Arginine Appearance in Murine Malaria May Explain Hypoargininemia in Children With Cerebral Malaria.
M. Alkaitis, Honghui Wang, A. Ikeda, Carol A. Rowley +8 more
2016Journal of Infectious Diseases27 citations Open access
Semantic Scholar
Biochemical characterization of AeD7L2 and its physiological relevance in blood feeding in the dengue mosquito vector, Aedes aegypti
Inés Martín-Martín, O. Kern, Steven D. Brooks, L. B. Smith +4 more
2020The FEBS Journal20 citations Open access
Semantic Scholar
Infrared Imaging of Nitric Oxide-Mediated Blood Flow in Human Sickle Cell Disease
A. Gorbach, Hans C. Ackerman, Wei-Min Liu, J. Meyer +10 more
2012Microvascular Research20 citations Open access
Semantic Scholar
Plasmodium Infection Is Associated with Impaired Hepatic Dimethylarginine Dimethylaminohydrolase Activity and Disruption of Nitric Oxide Synthase Inhibitor/Substrate Homeostasis
Jessica H. Chertow, M. Alkaitis, G. Nardone, A. Ikeda +11 more
2015PLoS Pathogens19 citations Open access
Semantic Scholar
Antioxidant therapy: Reducing malaria severity?
Hans C. Ackerman, Steven D. Beaudry, Rick M. Fairhurst
2009Critical Care Medicine19 citations Open access
Semantic Scholar
The Association of Blood Transfusion with Outcome among African Children Hospitalized with Plasmodium falciparum Malaria: A Prospective Multicentre Observational Study
Hans C. Ackerman, Aintzane Ayestaran, C. Olola, M. Jallow +9 more
2020The Lancet Haematology18 citations Open access
Semantic Scholar
Microvascular oxygen consumption during sickle cell pain crisis.
Carol A. Rowley, A. Ikeda, Miles Seidel, Tiffany C. Anaebere +8 more
2014Blood16 citations Open access
Semantic Scholar
Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice
Steven D. Brooks, Rachel L. Smith, A. S. Moreira, Hans C. Ackerman
2022bioRxiv12 citations Open access
Semantic Scholar
Experimental Babesia rossi infection induces hemolytic, metabolic, and viral response pathways in the canine host
Rachel L. Smith, A. Goddard, A. Boddapati, Steven D. Brooks +4 more
2021BMC Genomics12 citations Open access
Semantic Scholar
Cardiovascular Adaptations to Anemia and the Vascular Endothelium in Sickle Cell Disease Pathophysiology
Lydia H. Pecker, Hans C. Ackerman
201611 citations
Semantic Scholar
Tetrahydrobiopterin Supplementation Improves Phenylalanine Metabolism in a Murine Model of Severe Malaria
M. Alkaitis, Hans C. Ackerman
2016ACS Infectious Diseases11 citations Open access
Semantic Scholar
Alpha Globin Gene Copy Number Is Associated with Prevalent Chronic Kidney Disease and Incident End-Stage Kidney Disease among Black Americans
A. P. Ruhl, Neal O. Jeffries, Yu Yang, Rakhi P. Naik +11 more
2021Journal of the American Society of Nephrology9 citations Open access
Semantic Scholar
Whole blood transfusion improves vascular integrity and increases survival in artemether-treated experimental cerebral malaria
Saba Gul, F. Ribeiro-Gomes, A. S. Moreira, G. Sanches +4 more
2021Scientific Reports9 citations Open access
Semantic Scholar
The PAGODAS protocol: pediatric assessment group of dengue and Aedes saliva protocol to investigate vector-borne determinants of Aedes-transmitted arboviral infections in Cambodia
J. Manning, F. Oliveira, D. Parker, Chanaki Amaratunga +16 more
2018Parasites & Vectors8 citations Open access
Semantic Scholar
Rapid vs. delayed infrared responses after ischemia reveal recruitment of different vascular beds
Ken Chang, Stephen Yoon, Niral Sheth, Miles Seidel +7 more
2015Quantitative InfraRed Thermography Journal8 citations Open access
Semantic Scholar
The Tumor Lysis Syndrome
J. Elinoff, R. Salit, Hans C. Ackerman
2011New England Journal of Medicine6 citations Open access
Semantic Scholar
Management of severe malaria: Enthusiasm for fluid resuscitation dampened by lung water
Hans C. Ackerman
2013Critical Care Medicine5 citations Open access
Semantic Scholar
Intravenous whole blood transfusion results in faster recovery of vascular integrity and increased survival in experimental cerebral malaria
Sabahat Gul, Hans C. Ackerman, C. Daniel-Ribeiro, L. Carvalho
2021bioRxiv4 citations Open access
Semantic Scholar
Hemoglobin Interacts with Endothelial Nitric Oxide Synthase to Regulate Vasodilation in Human Resistance Arteries
Steven D. Brooks, Olena Kamenyeva, Sundar Ganesan, Xian-Ke Zeng +8 more
2021medRxiv3 citations Open access
Semantic Scholar
Alpha globin gene copy number and hypertension risk among Black Americans
A. P. Ruhl, Neal O. Jeffries, Yu Yang, Orlando M. Gutiérrez +11 more
2022medRxiv2 citations Open access
Semantic Scholar
HBA Copy Number and Kidney Disease Risk among Black Americans: a Longitudinal Cohort Study
A. P. Ruhl, Neal O. Jeffries, Yu Yang, Rakhi P. Naik +11 more
2021medRxiv2 citations Open access
Semantic Scholar
Time-to-death is a potential confounder in observational studies of blood transfusion in severe malaria
J. A. Watson, S. Leopold, A. Dondorp, Nicholas J. White +9 more
2020The Lancet Haematology2 citations Open access
Semantic Scholar
A better biomarker for cerebral malaria: In the eye of the beheld?
Hans C. Ackerman, Ryan W. Carroll, C. Casals-Pascual
2012Critical Care Medicine2 citations Open access
Semantic Scholar
A biomarker approach to syndrome-based treatment of severe childhood illness in malaria-endemic areas
Hans C. Ackerman, C. Casals-Pascual
2018Malaria Journal1 citations Open access
Semantic Scholar
Inactivation of Each of the Duplicated Hba Genes in Mice using a Stochastic CRISPR‐Cas9 Approach
Xianke Zeng, Kyoungin Cho, Steven E. Brooks, J. Khillan +1 more
2021The FASEB Journal0 citations Open access
Semantic Scholar
The Alpha Subunit of Hemoglobin Interacts with Endothelial Nitric Oxide Synthase to Regulate Feedback Vasodilation in Human Resistance Arteries
Steven E. Brooks, Olena Kamenyeva, S. Ganesan, Xian-Ke Zeng +4 more
2021The FASEB Journal0 citations
Semantic Scholar
The Impact of Angiotensin Converting Enzyme Inhibition and/or Angiotensin Receptor Blockade on Tissue Expression of the SARS‐CoV‐2 Receptor ACE2 in Mice
Aline Silva Moreira, Steven D. Brooks, Rachel L. Smith, Ian N. Moore +1 more
2021The FASEB Journal0 citations Open access
Semantic Scholar
Expression and Localization of Alpha Globin in the Vascular Endothelium
Steven D. Brooks, Olena Kamenyeva, Xianke Zeng, Rachel L. Smith +3 more
2020The FASEB Journal0 citations Open access
Semantic Scholar
Cerebral Vascular Function in a Murine Model of Experimental Cerebral Malaria
Steven D. Brooks, Aline da Silva Moreira, L. Carvalho, Hans C. Ackerman
2019The FASEB Journal0 citations
Semantic Scholar
Alpha Globin Gene Copy Number Is Associated with Kidney Disease Among Black Individuals
A. P. Ruhl, N. Jeffries, Yu Yang, Rakhi P. Naik +10 more
2019Blood0 citations Open access
Semantic Scholar
The assessment of interaction between eNOS and Alpha hemoglobin by Bio‐layer Interferometry
D. Ma, Hans C. Ackerman
20180 citations
Semantic Scholar
Inducible Deletion of Endothelial Hba1 Significantly Reduces Exercise Fitness in Mice
Alexander S. Keller, Steven E. Brooks, Aditi Islam, T. C. Stevenson Keller +5 more
20180 citations
Semantic Scholar
Microfluidic Models of the Microvasculature for Red Blood Cell Metrology in Sickle Cell Disease
J. Betz, D. Laván, Hans C. Ackerman
2016The FASEB Journal0 citations Open access
Semantic Scholar
Ischemic Pain Testing Demonstrates Hypoxia Dependent Early Pain and Hypoxia Independent Persistent Pain Responses in Adults with Sickle Cell Anemia
K. Vaughan, Joseph Kim, Daniel Lichy, Nathan S Fishman +9 more
20160 citations
Semantic Scholar
Altered Oxygenation, Vascular and Ischemic Pain Responses in Adults with Sickle Cell Anemia
Nathan S Fishman, Joseph Kim, Daniel Lichy, K. Vaughan +8 more
20150 citations
Semantic Scholar
Biochemical determinants of nitric oxide synthesis in severe malaria
D. Roberts, Hans C. Ackerman
20140 citations
Semantic Scholar
Cerebral malaria in mice deficient for NADPH oxidase or SOD1 or in the presence of DETC or DPI.
I. Francischetti, E. Gordon, Bruna Bizzarro, Nidhi Gera +14 more
20140 citations Open access
Semantic Scholar
Inward cholesterol gradient of the membrane system installed by malaria parasites in normal and sickle erythrocytes
F. Tokumasu, Georgeta Crivat, Hans C. Ackerman, Jeeseong Hwang +1 more
20140 citations
Semantic Scholar
Laser Speckle Contrast Imaging Characterizes Delayed Reperfusion After Transient Brachial Artery Occlusion in Patients with Sickle Cell Diseas
A. Ikeda, Tiffany C. Anaebere, N. Malik, M. Antalek +5 more
20120 citations
Semantic Scholar
and Exhibits Therapeutic Potential to Treat Severe Malaria Defibrotide Interferes With Several Steps of the Coagulation-Inflammation Cycle
R. Monteiro, M. Kotsyfakis, A. Sá-Nunes, Hans C. Ackerman +15 more
20120 citations
Semantic Scholar

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C. Casals-Pascual×6
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C. Casals-Pascual — researcher profile on SciRah
A. Gorbach×6
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A. Gorbach — researcher profile on SciRah
Rachel L. Smith×6
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Rachel L. Smith — researcher profile on SciRah
Yu Yang×5
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Yu Yang — researcher profile on SciRah

Steven D. Brooks

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Steven D. Brooks — researcher profile on SciRah

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A. Ikeda — researcher profile on SciRah

Lydia H. Pecker×5

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Lydia H. Pecker — researcher profile on SciRah

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A. P. Ruhl — researcher profile on SciRah

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T. Wellems — researcher profile on SciRah

Samuel E. Moretz×4

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Samuel E. Moretz — researcher profile on SciRah

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C. Long — researcher profile on SciRah

A. Sá-Nunes×4

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A. Sá-Nunes — researcher profile on SciRah