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Frank J Simutis · SciRah

Researcher profile · Semantic Scholar

Frank J Simutis

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Frank J Simutis — researcher profile on SciRah

h-index: 10
Works: 19
Citations: 269

Most-cited papers

Pharmacodynamics of Selective Inhibition of γ-Secretase by Avagacestat
C. Albright, R. Dockens, J. Meredith, R. Olson +29 more
2013Journal of Pharmacology and Experimental Therapeutics62 citations
Semantic Scholar
Methodological considerations for measuring biofluid-based microRNA biomarkers
B. Chorley, E. Atabakhsh, G. Doran, Jean-Charles Gautier +14 more
2021Critical Reviews in Toxicology38 citations Open access
Semantic Scholar
Failure of antigen-stimulated gammadelta T cells and CD4+ T cells from sensitized cattle to upregulate nitric oxide and mycobactericidal activity of autologous Mycobacterium avium subsp. paratuberculosis-infected macrophages.
Frank J Simutis, Douglas E. Jones, J. Hostetter
2007Veterinary Immunology and Immunopathology26 citations Open access
Semantic Scholar
Discovery and Preclinical Evaluation of BMS-955829, a Potent Positive Allosteric Modulator of mGluR5.
Fu-Kang Yang, L. Snyder, Anand Balakrishnan, J. M. Brown +21 more
2016ACS Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron
B. Chorley, H. Ellinger-Ziegelbauer, M. Tackett, Frank J Simutis +10 more
2020Toxicological Sciences23 citations Open access
Semantic Scholar
Kidney Safety Assessment: Current Practices in Drug Development.
Sean P. Troth, Frank J Simutis, G. Friedman, Susan Todd +1 more
2019Seminars in Nephrology19 citations
Semantic Scholar
Vancomycin for multi-drug resistant Enterococcus faecium cholangiohepatitis in a cat
M. Pressel, L. Fox, M. Apley, Frank J Simutis
2005Journal of feline medicine and surgery17 citations Open access
Semantic Scholar
Investigation of antigen-specific T-cell responses and subcutaneous granuloma development during experimental sensitization of calves with Mycobacterium avium subsp paratuberculosis.
Frank J Simutis, N. Cheville, Douglas E. Jones
2005American Journal of Veterinary Research16 citations Open access
Semantic Scholar
Nonclinical Safety Assessment of the &ggr;-Secretase Inhibitor Avagacestat
Frank J Simutis, T. Sanderson, G. Pilcher, M. Graziano
2018Toxicological Sciences15 citations
Semantic Scholar
Abstract LB-B33: Nonclinical safety evaluation of two distinct second generation variants of anti-CTLA4 monoclonal antibody, ipilimumab, in monkeys
K. Price, Frank J Simutis, A. Fletcher, Lila Ramaiah +15 more
201813 citations
Semantic Scholar
Mycobacterium avium subspecies paratuberculosis infection of cattle does not diminish peripheral blood-derived macrophage mycobactericidal activity.
Jesse M. Hostetter, W. Zhang, Frank J Simutis
2006Immunology Letters6 citations
Semantic Scholar
Decreased immune response in monkeys administered a human T-effector cell agonist (OX40) antibody.
J. Gamse, W. Freebern, Rashade Haynes Ii, Frank J Simutis +5 more
2020Toxicology and Applied Pharmacology3 citations Open access
Semantic Scholar
Determination of relative Notch1 and gamma-secretase-related gene expression in puromycin-treated microdissected rat kidneys.
D. Simic, Frank J Simutis, Catherine Euler, Christina Thurby +5 more
2013Gene Expression3 citations Open access
Semantic Scholar
An Improved Method of Tissue Adhesion on Glass Microslides for Immunohistochemical Evaluation by the Use of Selected Tissues from the Dog and Monkey
Christina Thurby, M. White, Frank J Simutis, S. Gillham +1 more
20093 citations
Semantic Scholar
Investigations on the Relationship between Ovarian, Endocrine, and Renal Findings in Nonclinical Safety Studies of the γ-secretase Inhibitor Avagacestat.
Frank J Simutis, T. Sanderson, G. Pilcher, M. Graziano
2019Toxicological Sciences2 citations
Semantic Scholar
Proceedings of the 2025 Division of Translational Toxicology Satellite Symposium
M. Cora, T. Crabbs, Frank J Simutis, K. Janardhan +3 more
2025Toxicologic pathology (Print)0 citations
Semantic Scholar
Multicolor Ramsey Numbers for Berge cycles
Zachary DeStefano, H. Mahon, Frank J Simutis, Michael Tait
2021Electronic Journal of Combinatorics0 citations Open access
Semantic Scholar
JPET # 199356 3 Recommended section assignment to guide listing in table of contents : Neuropharmacology
C. Albright, R. Dockens, J. Meredith, R. Olson +29 more
20120 citations
Semantic Scholar
Subcutaneous challenge of cattle with Mycobacterium avium subspecies paratuberculosis: an experimental system to study CD4+ T cell and gamma-delta T cell responses to infection
Frank J Simutis
20050 citations
Semantic Scholar

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G. Pilcher — researcher profile on SciRah
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