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R. Dockens · SciRah

Researcher profile · Semantic Scholar

R. Dockens

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R. Dockens — researcher profile on SciRah

h-index: 15
Works: 41
Citations: 1,419

Most-cited papers

Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease.
V. Coric, C. van Dyck, S. Salloway, N. Andreasen +17 more
2012Archives of Neurology366 citations Open access
Semantic Scholar
Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.
V. Coric, S. Salloway, C. van Dyck, B. Dubois +24 more
2015JAMA Neurology221 citations Open access
Semantic Scholar
Multicenter, randomized, double‐blind, active comparator and placebo‐controlled trial of a corticotropin‐releasing factor receptor‐1 antagonist in generalized anxiety disorder
V. Coric, Howard H. Feldman, D. Oren, A. Shekhar +12 more
2010Depression and Anxiety158 citations Open access
Semantic Scholar
Do corticotropin releasing factor-1 receptors influence colonic transit and bowel function in women with irritable bowel syndrome?
S. Sweetser, M. Camilleri, S. L. Linker Nord, D. Burton +5 more
2009American Journal of Physiology - Gastrointestinal and Liver Physiology114 citations Open access
Semantic Scholar
Anticonvulsant activity of some 4-aminobenzamides.
C. Clark, M. M. Wells, Ricky T. Sansom, George N. Norris +2 more
1984Journal of Medicinal Chemistry85 citations
Semantic Scholar
Multicenter, randomized, double-blind, placebo-controlled, single-ascending dose study of the oral γ-secretase inhibitor BMS-708163 (Avagacestat): tolerability profile, pharmacokinetic parameters, and pharmacodynamic markers.
G. Tong, Jun-Sheng Wang, Oleksandr Sverdlov, Shu-Pang Huang +10 more
2012Clinical Therapeutics68 citations
Semantic Scholar
Pharmacodynamics of Selective Inhibition of γ-Secretase by Avagacestat
C. Albright, R. Dockens, J. Meredith, R. Olson +29 more
2013Journal of Pharmacology and Experimental Therapeutics62 citations
Semantic Scholar
A Placebo-Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Avagacestat (BMS-708163) in Healthy Young and Elderly Subjects
R. Dockens, Jun-Sheng Wang, Lorna Castaneda, Oleksandr Sverdlov +9 more
2012Clinical Pharmacokinetics44 citations
Semantic Scholar
Calculation and mitigation of isotopic interferences in liquid chromatography-mass spectrometry/mass spectrometry assays and its application in supporting microdose absolute bioavailability studies.
Huidong Gu, Jian Wang, A. Aubry, Hao Jiang +7 more
2012Analytical Chemistry37 citations
Semantic Scholar
6-Hydroxybuspirone Is a Major Active Metabolite of Buspirone: Assessment of Pharmacokinetics and 5-Hydroxytryptamine1A Receptor Occupancy in Rats
H. Wong, R. Dockens, L. Pajor, S. Yeola +6 more
2007Drug Metabolism And Disposition35 citations
Semantic Scholar
Effects of Single Doses of Avagacestat (BMS-708163) on Cerebrospinal Fluid Aβ Levels in Healthy Young Men
G. Tong, Lorna Castaneda, Jun-Sheng Wang, Oleksandr Sverdlov +9 more
2012Clinical drug investigation32 citations
Semantic Scholar
Brasofensine Treatment for Parkinson's Disease in Combination with Levodopa/Carbidopa
Edyta J. Frackiewicz, S. Jhee, T. Shiovitz, J. Webster +5 more
2002The Annals of Pharmacotherapy26 citations
Semantic Scholar
Coadministration of nefazodone and benzodiazepines: IV. A pharmacokinetic interaction study with lorazepam.
D. Greene, D. Salazar, R. Dockens, P. Kroboth +1 more
1995Journal of Clinical Psychopharmacology17 citations
Semantic Scholar
A contrast in safety, pharmacokinetics and pharmacodynamics across age groups after a single 50 mg oral dose of the γ-secretase inhibitor avagacestat.
G. Tong, Jun-Sheng Wang, Oleksandr Sverdlov, Shu-Pang Huang +10 more
2013British Journal of Clinical Pharmacology16 citations Open access
Semantic Scholar
Comparison of Pharmacokinetics of Lanoteplase and Alteplase During Acute Myocardial Infarction
J. Kostis, R. Dockens, U. Thadani, V. Bethala +8 more
2002Clinical Pharmacokinetics16 citations
Semantic Scholar
Lack of an effect of nefazodone on the pharmacokinetics and pharmacodynamics of theophylline during concurrent administration in patients with chronic obstructive pulmonary disease.
R. Dockens, D. Rapoport, D. Roberts, D. Greene +1 more
1995British Journal of Clinical Pharmacology14 citations Open access
Semantic Scholar
In Vitro and In Vivo Metabolism and Pharmacokinetics of BMS-562086, a Potent and Orally Bioavailable Corticotropin-Releasing Factor-1 Receptor Antagonist
Lian Zhou, R. Dockens, Peggy Liu-Kreyche, S. Grossman +1 more
2012Drug Metabolism And Disposition12 citations Open access
Semantic Scholar
Development of oral extended release formulations of 6‐hydroxybuspirone
S. Nicholson, P. Timmins, R. Dockens, A. Connor +5 more
2012Biopharmaceutics & drug disposition12 citations
Semantic Scholar
P3‐301: 11β HSD‐1 inhibition reduces Aβ pathology in a mouse model of Alzheimer's disease
Jun-Sheng Wang, Lorna Castaneda, Alex Sverdlov, Shu-Pang Huang +10 more
201011 citations Open access
Semantic Scholar
O3‐07‐07: A study to evaluate the effects of single oral doses of BMS‐708163 in the cerebrospinal fluid of healthy young men
G. Tong, Lorna Castaneda, Jun-Sheng Wang, A. Sverdlov +9 more
201011 citations
Semantic Scholar
Lack of Electrocardiographic Effects of Deucravacitinib in Healthy Subjects
A. Chimalakonda, S. Singhal, R. Darbenzio, R. Dockens +7 more
2022Clinical pharmacology in drug development10 citations Open access
Semantic Scholar
The lack effect of food on the bioavailability of nefazodone tablets.
R. Dockens, D. Greene, R. Barbhaiya
1996Biopharmaceutics & drug disposition10 citations
Semantic Scholar
Disposition and Metabolism of [14C]Brasofensine in Rats, Monkeys, and Humans
Mingshe Zhu, D. Whigan, Shu-Ying Chang, R. Dockens
2008Drug Metabolism And Disposition7 citations
Semantic Scholar
T1405 Effects of a Novel Corticotrophin Releasing Factor Receptor-1 Antagonist, BMS-562086, On Gastrointestinal and Colonic Transit and Bowel Habits in Patients with Diarrhea-Predominant Irritable Bowel Syndrome (D-IBS)
S. Sweetser, S. L. Nord, D. Burton, A. Grudell +7 more
20086 citations
Semantic Scholar
Pharmacokinetics and Safety of the Tyrosine Kinase 2 Inhibitor Deucravacitinib in Healthy Chinese Subjects
Shan Jing, Yang Lin, R. Dockens, D. Marchisin +5 more
2023Dermatologic Therapy5 citations Open access
Semantic Scholar
Pre-absorption physicochemical compatibility assessment of 8-drug metabolic cocktail.
Ching Kim Tye, Zhan-Bin Wang, R. Dockens, B. Vakkalagadda +4 more
2016International journal of pharmaceutics5 citations
Semantic Scholar
Liquid chromatographic determination of clorazepate decomposition rates
C. Clark, W. Ravis, R. Dockens, J. M. Barksdale +2 more
19825 citations
Semantic Scholar
IC‐P‐058: Encoding of novel complex visual scenes in presymptomatic Alzheimer's disease
R. Dockens, E. Chung, Oleksandr Sverdlov, H. Soares +3 more
20123 citations Open access
Semantic Scholar
P349 Cyclosporine has no clinically meaningful effect on pharmacokinetics (PK) of BMS-986165, an oral selective tyrosine kinase 2 (TYK2) inhibitor, in healthy subjects
A. Chimalakonda, J. Jones, R. Dockens, J. Throup +2 more
2019Journal of Crohn's & Colitis2 citations
Semantic Scholar
P638 BMS-986165, an oral selective tyrosine kinase 2 (TYK2) inhibitor, does not affect the pharmacokinetics of methotrexate in healthy subjects
A. Chimalakonda, J. Jones, R. Dockens, J. Throup +2 more
2019Journal of Crohn's & Colitis2 citations
Semantic Scholar
P3‐289: Effect of concomitant administration of multiple doses of BMS‐708163 on safety, tolerability, and the pharmacokinetics of midazolam, warfarin, caffeine, omeprazole, and dextromethorphan in healthy male subjects by administration of a modified Cooperstown cocktail
R. Dockens, J. Karkas, Ming Zheng, Alex Sverdlov +9 more
20102 citations
Semantic Scholar
P3‐298: The safety, tolerability, pharmacokinetics and pharmacodynamics of single doses of BMS‐708163 in young and elderly subjects
G. Tong, Jun-Sheng Wang, A. Sverdlov, Shu-Pang Huang +11 more
20101 citations
Semantic Scholar
Liquid chromatographic determination of serum levels of d,l-4-amino-N-(alpha-methylbenzyl)-benzamide, a new benzamide anticonvulsant.
R. Dockens, W. Ravis, C. Clark
1988Journal of Chromatographic Science1 citations
Semantic Scholar
Lack of ECG effects of BMS-986165, an oral, selective tyrosine kinase 2 (TYK2) inhibitor: results from a thorough QT study in healthy subjects
I. Girgis, A. Chimalakonda, JP Jones, R. Dockens +5 more
2019SKIN The Journal of Cutaneous Medicine0 citations Open access
Semantic Scholar
(BMS 708163) IN HEALTHY JAPANESE AND NON-JAPANESE SUBJECTS
E. Chung, Oleksandr Sverdlov, H. Soares, Bing He +5 more
20190 citations
Semantic Scholar
P1‐239: Randomized, placebo‐controlled, double blind, single‐ and multiple‐dose study to evaluate the pharmacokinetics, safety and tolerability of avagacestat (BMS‐708163) in healthy young male and elderly male and female Chinese subjects
J. Karkas, R. Dockens, Oleksandr Sverdlov, Heather Sevinsky +3 more
20120 citations
Semantic Scholar
P1‐240: The effect of concomitant administration of multiple doses of avagacestat on the pharmacokinetics of either donepezil or galantamine in healthy subjects
R. Dockens, J. Karkas, Oleksandr Sverdlov, Bing He +2 more
20120 citations Open access
Semantic Scholar
JPET # 199356 3 Recommended section assignment to guide listing in table of contents : Neuropharmacology
C. Albright, R. Dockens, J. Meredith, R. Olson +29 more
20120 citations
Semantic Scholar
Buspirone is a Major Active Metabolite of Buspirone : Assessment of Pharmacokinetics and 5-HT 1 A Receptor Occupancy in Rats
H. Wong, R. Dockens, L. Pajor, S. Yeola +6 more
20070 citations
Semantic Scholar
Disposition and Metabolism of [ 14 C ] Brasofensine in Rats , Monkeys , and Humans
Mingshe Zhu, D. Whigan, Shu-Ying Chang, R. Dockens
20070 citations
Semantic Scholar
Liquid Chromatographic Determination of 4-Amino-N-(2,6-dimethylphenyl)-benzamide in Rat Serum and Urine
R. Dockens, W. Ravis, C. Clark
19870 citations
Semantic Scholar

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