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N. Yanamandra · SciRah

Researcher profile · Semantic Scholar

N. Yanamandra

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N. Yanamandra — researcher profile on SciRah

h-index: 28
Works: 65
Citations: 2,569

Most-cited papers

Selective inhibition of matrix metalloproteinase-14 blocks tumor growth, invasion, and angiogenesis.
L. Devy, Li-Li Huang, L. Naa, N. Yanamandra +23 more
2009Cancer Research347 citations Open access
Semantic Scholar
Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis
S. Lakka, C. Gondi, N. Yanamandra, W. Olivero +3 more
2004Oncogene303 citations Open access
Semantic Scholar
Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments
Jong W Yu, S. Bhattacharya, N. Yanamandra, D. Kilian +23 more
2018PLoS ONE175 citations Open access
Semantic Scholar
Tipifarnib and Bortezomib Are Synergistic and Overcome Cell Adhesion–Mediated Drug Resistance in Multiple Myeloma and Acute Myeloid Leukemia
N. Yanamandra, Nandita M Colaco, N. Parquet, Robert W Buzzeo +5 more
2006Clinical Cancer Research112 citations Open access
Semantic Scholar
Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo
Rocio Montes de Oca, A. Alavi, Nicholas J. Vitali, S. Bhattacharya +26 more
2021Molecular Cancer Therapeutics105 citations Open access
Semantic Scholar
Blockade of cathepsin B expression in human glioblastoma cells is associated with suppression of angiogenesis
N. Yanamandra, K. Gumidyala, K. Waldron, M. Gujrati +4 more
2004Oncogene98 citations
Semantic Scholar
Adenovirus-mediated expression of antisense MMP-9 in glioma cells inhibits tumor growth and invasion
S. Lakka, Mannari Rajan, C. Gondi, N. Yanamandra +10 more
2002Oncogene95 citations Open access
Semantic Scholar
Synergistic down-regulation of urokinase plasminogen activator receptor and matrix metalloproteinase-9 in SNB19 glioblastoma cells efficiently inhibits glioma cell invasion, angiogenesis, and tumor growth.
S. Lakka, C. Gondi, N. Yanamandra, D. Dinh +3 more
2003Cancer Research89 citations
Semantic Scholar
Expression of antisense uPAR and antisense uPA from a bicistronic adenoviral construct inhibits glioma cell invasion, tumor growth, and angiogenesis
C. Gondi, S. Lakka, N. Yanamandra, Khawar Siddique +4 more
2003Oncogene89 citations
Semantic Scholar
The mutational spectrum of brachydactyly type C.
D. Everman, C. Bartels, Yue Yang, N. Yanamandra +15 more
2002American journal of medical genetics85 citations Open access
Semantic Scholar
Adenovirus-Mediated Expression of Antisense Urokinase Plasminogen Activator Receptor and Antisense Cathepsin B Inhibits Tumor Growth, Invasion, and Angiogenesis in Gliomas
C. Gondi, S. Lakka, N. Yanamandra, W. Olivero +5 more
2004Cancer Research80 citations Open access
Semantic Scholar
Modulation of cystatin C expression impairs the invasive and tumorigenic potential of human glioblastoma cells
S. Konduri, N. Yanamandra, Khawar Siddique, A. Joseph +7 more
2002Oncogene74 citations
Semantic Scholar
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), in human glioma cells
S. Konduri, K. Srivenugopal, N. Yanamandra, D. Dinh +8 more
2003Oncogene67 citations Open access
Semantic Scholar
Recombinant adeno‐associated virus (rAAV) expressing TFPI‐2 inhibits invasion, angiogenesis and tumor growth in a human glioblastoma cell line
N. Yanamandra, Shakuntala Kondraganti, C. Gondi, M. Gujrati +3 more
2005International Journal of Cancer65 citations Open access
Semantic Scholar
Promoter methylation and silencing of the tissue factor pathway inhibitor-2 (TFPI-2), a gene encoding an inhibitor of matrix metalloproteinases in human glioma cells.
S. Konduri, K. Srivenugopal, N. Yanamandra, D. Dinh +8 more
2003Oncogene60 citations Open access
Semantic Scholar
High OX-40 expression in the tumor immune infiltrate is a favorable prognostic factor of overall survival in non-small cell lung cancer
E. Massarelli, V. Lam, E. Parra, J. Rodriguez-Canales +12 more
2019Journal of Immunotherapy for Cancer59 citations Open access
Semantic Scholar
Down-regulation of Integrin αvβ3 Expression and Integrin-mediated Signaling in Glioma Cells by Adenovirus-mediated Transfer of Antisense Urokinase-type Plasminogen Activator Receptor (uPAR) and Sense p16 Genes*
Yoshiaki Adachi, S. Lakka, Nirmala Chandrasekar, N. Yanamandra +10 more
2001Journal of Biological Chemistry54 citations Open access
Semantic Scholar
First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1)
S. Postel-Vinay, V. Lam, W. Ros, T. Bauer +28 more
2023Journal for ImmunoTherapy of Cancer51 citations Open access
Semantic Scholar
Radiation followed by OX40 stimulation drives local and abscopal antitumor effects in an anti-PD1-resistant lung tumor model
S. Niknam, H. Barsoumian, J. Schoenhals, H. Jackson +14 more
2018Clinical Cancer Research51 citations Open access
Semantic Scholar
Anti-OX40 antibody directly enhances the function of tumor-reactive CD8+ T cells and synergizes with PI3Kβ inhibition in PTEN loss melanoma
Weiyi Peng, Leila J. Williams, Chunyu Xu, Brenda D. Melendez +16 more
2019Clinical Cancer Research44 citations Open access
Semantic Scholar
Tipifarnib-Induced Apoptosis in Acute Myeloid Leukemia and Multiple Myeloma Cells Depends on Ca2+ Influx through Plasma Membrane Ca2+ Channels
N. Yanamandra, Robert W Buzzeo, Mark Gabriel, L. Hazlehurst +3 more
2011Journal of Pharmacology and Experimental Therapeutics42 citations Open access
Semantic Scholar
Expression of matrix metalloproteinases, their inhibitors, and urokinase plasminogen activator in human meningiomas.
Khawar Siddique, N. Yanamandra, M. Gujrati, D. Dinh +2 more
2003International Journal of Oncology40 citations
Semantic Scholar
Modulation of invasive properties of human glioblastoma cells stably expressing amino-terminal fragment of urokinase-type plasminogen activator
S. Mohanam, Nirmala Chandrasekar, N. Yanamandra, Siddique Khawar +4 more
2002Oncogene40 citations Open access
Semantic Scholar
Elevated levels of cathepsin B in human glioblastoma cell lines.
S. Konduri, S. Lakka, A. Tasiou, N. Yanamandra +5 more
2001International Journal of Oncology39 citations
Semantic Scholar
A novel role of tissue factor pathway inhibitor-2 in apoptosis of malignant human gliomas.
A. Tasiou, S. Konduri, N. Yanamandra, D. Dinh +4 more
2001International Journal of Oncology37 citations
Semantic Scholar
Suppression of glioma invasion and growth by adenovirus-mediated delivery of a bicistronic construct containing antisense uPAR and sense p16 gene sequences
Yoshiaki Adachi, Nirmala Chandrasekar, Yoshiaki Kin, S. Lakka +12 more
2002Oncogene34 citations Open access
Semantic Scholar
Triterpenoids from Glycine max decrease invasiveness and induce caspase-mediated cell death in human SNB19 glioma cells
N. Yanamandra, M. Berhow, S. Konduri, D. Dinh +3 more
2003Clinical and Experimental Metastasis32 citations
Semantic Scholar
Anticancer effects of the novel 1α, 25‐dihydroxyvitamin D3 hybrid analog QW1624F2‐2 in human neuroblastoma
C. D. Reddy, R. Patti, Asha Guttapalli, J. Maris +5 more
2006Journal of Cellular Biochemistry30 citations
Semantic Scholar
Downregulation of urokinase-type plasminogen activator receptor (uPAR) induces caspase-mediated cell death in human glioblastoma cells
N. Yanamandra, S. Konduri, S. Mohanam, D. Dinh +5 more
2000Clinical and Experimental Metastasis25 citations
Semantic Scholar
The response to anti–PD-1 and anti–LAG-3 checkpoint blockade is associated with regulatory T cell reprogramming
Annah S. Rolig, Xi-Yu Peng, E. Sturgill, Nisha Holay +14 more
2025Science Translational Medicine20 citations
Semantic Scholar
Activation of caspase-9 with irradiation inhibits invasion and angiogenesis in SNB19 human glioma cells
N. Yanamandra, Shakuntala Kondraganti, S. Srinivasula, M. Gujrati +3 more
2004Oncogene20 citations Open access
Semantic Scholar
Abstract CT150: A first-in-human phase I study of the OX40 agonist GSK3174998 (GSK998) +/- pembrolizumab in patients (Pts) with selected advanced solid tumors (ENGAGE-1)
S. Postel-Vinay, V. Lam, W. Ros, T. Bauer +28 more
2020Tumor Biology19 citations
Semantic Scholar
Physiological and chemical inducers of tissue factor pathway inhibitor-2 in human glioma cells.
S. Konduri, N. Yanamandra, D. Dinh, W. Olivero +4 more
2003International Journal of Oncology16 citations
Semantic Scholar
Combined Targeting of PD-1 and TIM-3 in Patients with Locally Advanced or Metastatic Non–Small Cell Lung Cancer: AMBER Part 2B
D. Davar, Z. Eroglu, M. Milhem, C. Becerra +12 more
2025Clinical Cancer Research15 citations
Semantic Scholar
Minimal and inducible regulation of tissue factor pathway inhibitor-2 in human gliomas
S. Konduri, Francis Ali Osman, C. Rao, H. Srinivas +9 more
2002Oncogene15 citations
Semantic Scholar
Combined Targeting of PD-1 and TIM-3 in Patients with Locally Advanced or Metastatic Melanoma: AMBER Cohorts 1c, 1e, and 2A
D. Davar, Z. Eroglu, Casilda Llácer Pérez, B. Di Pace +8 more
2025Clinical Cancer Research12 citations
Semantic Scholar
Impact of isotype on the mechanism of action of agonist anti-OX40 antibodies in cancer: implications for therapeutic combinations
J. Willoughby, L. Dou, S. Bhattacharya, H. Jackson +28 more
2024Journal for ImmunoTherapy of Cancer8 citations Open access
Semantic Scholar
Synergy of TLR4 agonist GSK1795091, an innate immune activator, with agonistic antibody against co-stimulatory immune checkpoint molecule OX40 in cancer immunotherapy.
Hua Gao, S. Bhattacharya, C. Matheny, N. Yanamandra +13 more
20188 citations
Semantic Scholar
Regression of pre-established intracranial tumor growth by ON 01910.Na, a selective anticancer agent currently in phase I trials.
C. Gondi, N. Kandhukuri, N. Yanamandra, M. Reddy +2 more
2006Journal of Clinical Oncology3 citations
Semantic Scholar
Evaluation of OX40 receptor density, influence of IgG Isotype and dosing paradigm in anti-OX40-mediated efficacy and biomarker responses with PD-1 blockade.
H. Jackson, S. Bhattacharya, P. Bojczuk, D. Kilian +13 more
2018Annals of Oncology2 citations Open access
Semantic Scholar
Abstract 1637: ICOS agonism induces potent immune activation and anti-tumor response in non-clinical models
S. Yadavilli, Tian-Qiang Zhang, A. Hahn, L. Seestaller-Wehr +15 more
20172 citations
Semantic Scholar
Abstract 4864: Engaging the immune system with GSK3174998, a potent anti-OX40 agonist antibody
C. Toniatti, N. Yanamandra, K. Voo, Amin Al-Shami +17 more
20162 citations
Semantic Scholar
Angiogenesis , and Tumor Growth Glioblastoma Cells Efficiently Inhibits Glioma Cell Invasion , Activator Receptor and Matrix Metalloproteinase-9 in SNB 19 Synergistic Down-Regulation of Urokinase Plasminogen
C. Gondi, N. Yanamandra, D. Dinh, W. Olivero +2 more
20032 citations
Semantic Scholar
Innate immunity as a target for novel therapeutics in triple negative breast cancer
T. Borgovan, N. Yanamandra, Hank Schmidt
2022Expert Opinion on Investigational Drugs1 citations
Semantic Scholar
Immunological profiling of tumor-infiltrating CD8+ T lymphocytes in non-small cell lung cancer, head and neck squamous cell carcinoma, breast cancer, and renal cell cancer
William L. Miller, Y. Koguchi, Johanna K. Kaufmann, N. Yanamandra +3 more
2022Journal of Immunology1 citations
Semantic Scholar
Response to anti-PD-1 and anti-LAG-3 immune checkpoint blockade is associated with induction of pro-inflammatory Tregs
Annah S. Rolig, E. Sturgill, C. Mick, Daniel C Rose +5 more
2020Journal of Immunology1 citations
Semantic Scholar
Abstract 4938: OX40 agonist antibody-based combination therapy with PI3Kβ selective inhibitor enhances T cell immunity
Weiyi Peng, Chunyu Xu, Brenda D. Melendez, H. Jackson +9 more
2018Immunology1 citations
Semantic Scholar
Inhibition of lung cancer cell invasion and metastasis by RNAi-mediated downregulation of urokinase plasminogen activator and its receptor.
S. Lakka, C. Gondi, R. A. Milhoan, S. Chittivelu +2 more
20041 citations
Semantic Scholar
Downregulation of integrin α v β 3 expression and integrin-mediated signaling in glioma cells by adenovirus-mediated transfer of antisense uPAR and sense p 16 genes
Yoshiaki Adachi, S. Lakka, Nirmala Chandrasekar, N. Yanamandra +9 more
20011 citations
Semantic Scholar
832 Integrative multi-omics analysis reveals enrichment of exhausted CD8 + and CD4 + CD8 + T cells in the renal cell carcinoma tumor microenvironment
M. Janghorban, Y. Koguchi, Noah D. Simons, Duncan C. Hindmarch +14 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar

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