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F. Zusi · SciRah

Researcher profile · Semantic Scholar

F. Zusi

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F. Zusi — researcher profile on SciRah

h-index: 14
Works: 35
Citations: 1,436

Most-cited papers

BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice*
J. Burke, M. Pattoli, Kurt R. Gregor, P. Brassil +8 more
2003Journal of Biological Chemistry472 citations Open access
Semantic Scholar
BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
J. Burke, M. Pattoli, Kurt R. Gregor, P. Brassil +8 more
2003Journal of Biological Chemistry255 citations
Semantic Scholar
A highly selective inhibitor of I kappa B kinase, BMS-345541, blocks both joint inflammation and destruction in collagen-induced arthritis in mice.
K. McIntyre, D. Shuster, Kathleen M. Gillooly, Donna M. Dambach +6 more
2003Arthritis & Rheumatism235 citations
Semantic Scholar
Rational design of RAR‐selective ligands revealed by RARβ crystal stucture
P. Germain, Sabrina Kammerer, Efrén Pérez, C. Peluso-Iltis +9 more
2004EMBO Reports93 citations Open access
Semantic Scholar
Selective retinoids and rexinoids in cancer therapy and chemoprevention.
F. Zusi, M. Lorenzi, Valérie Vivat-Hannah
2002Drug Discovery Today67 citations
Semantic Scholar
An inhibitor of IκB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice
J. Macmaster, Donna M. Dambach, D. Lee, K. Berry +3 more
2003Inflammation Research50 citations
Semantic Scholar
Progress in the discovery of BACE inhibitors.
L. Thompson, J. Bronson, F. Zusi
2005Current pharmaceutical design47 citations
Semantic Scholar
Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1.
Lawrence R. Marcin, Mendi A. Higgins, F. Zusi, Yun-Hui Zhang +19 more
2011Bioorganic & Medicinal Chemistry Letters33 citations
Semantic Scholar
of Selective Retinoid Ligands with Taxol ( Paclitaxel ) Synergistic Cytotoxicity Exhibited by Combination Treatment
Valérie Vivat-Hannah, Dan You, C. Rizzo, J. Daris +5 more
200133 citations
Semantic Scholar
An inhibitor of IkappaB kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice.
J. Macmaster, D. Dambach, D. Lee, K. Berry +3 more
2003Inflammation Research25 citations
Semantic Scholar
Retinoids as therapeutic agents: today and tomorrow.
Valérie Vivat-Hannah, F. Zusi
2005Mini-Reviews in Medical Chemistry24 citations
Semantic Scholar
Synthesis of 1,1-diarylethylenes from an α-stannyl β-silylstyrene
M. Belema, V. Nguyen, F. Zusi
200419 citations
Semantic Scholar
Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure-Activity Relationship.
J. Cook, F. Zusi, Ivar M. Mcdonald, D. King +32 more
2016Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
BMS-933043, a Selective α7 nAChR Partial Agonist for the Treatment of Cognitive Deficits Associated with Schizophrenia.
D. King, Christiana I. Iwuagwu, J. Cook, Ivar M. Mcdonald +24 more
2017ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Triazolopyridine ethers as potent, orally active mGlu2 positive allosteric modulators for treating schizophrenia.
Mendi A. Higgins, L. Marcin, F. Zusi, R. Gentles +18 more
2017Bioorganic & Medicinal Chemistry13 citations Open access
Semantic Scholar
Development of 4-Heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes] as α7 Nicotinic Receptor Agonists.
M. D. Hill, Haiquan Fang, H. King, Christiana I. Iwuagwu +18 more
2017ACS Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Evaluation of Retinoids as Therapeutic Agents in Dermatology
A. Lewin, M. E. Bos, F. Zusi, X. Nair +4 more
1994Pharmaceutical Research10 citations
Semantic Scholar
Design and synthesis of a novel series of 4-heteroarylamino-1'-azaspiro[oxazole-5,3'-bicyclo[2.2.2]octanes as α7 nicotinic receptor agonists 2. Development of 4-heteroaryl SAR.
Christiana I. Iwuagwu, D. King, Ivar M. Mcdonald, J. Cook +16 more
2017Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar
Biochemical and pharmacological properties of a new topical anti-inflammatory compound, 9-phenylnonanohydroxamic acid (BMY 30094)
K. Tramposch, F. Zusi, S. Marathe, P. Stanley +3 more
1990Agents and Actions5 citations
Semantic Scholar
Design and synthesis of a novel series of (1'S,2R,4'S)-3H-4'-azaspiro[benzo[4,5]imidazo[2,1-b]oxazole-2,2'-bicyclo[2.2.2]octanes] with high affinity for the α7 neuronal nicotinic receptor.
J. Cook, F. Zusi, M. D. Hill, Haiquan Fang +7 more
2017Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Structure of the ligand binding domain of the Retinoic Acid Receptor beta
P. Germain, Sabrina Kammerer, C. Peluso-Iltis, D. Tortolani +8 more
20041 citations
Semantic Scholar
The Requirement for a Retinoic Acid Lactone of 11-cis, 13-cis-Stereochemistry for Topical Dermatologic Activity
A. Lewin, R. Goehring, F. Zusi, G. J. Gendimenico +5 more
1994Pharmaceutical Research1 citations
Semantic Scholar
Frozen conformers of clotrimazole: reaction of imadazole with 1-Chloro-9-hydroxy-9-phenylxanthene.
P. L. Warner, Edward Luber, F. Zusi
1979Journal of Pharmacy and Science1 citations
Semantic Scholar
Quinuclidine compounds as ligands of the nicotinic acetylcholine receptor alpha7
J. Cook, Ivar M. Mcdonald, D. King, R. Olson +4 more
20090 citations
Semantic Scholar
IKK-2/NF-κB-DEPENDENT TRANSCRIPTION
F. Zusi, W. Pitts, J. Burke
20070 citations
Semantic Scholar
tricyclic compounds based thiazolo [4,5-b] pyridine imidazo-fused and pharmaceutical compositions comprising
M. Belema, A. Dyckman, P. Gill, J. Kempson +5 more
20050 citations
Semantic Scholar
Synthesis of 1,1‐Diarylethylenes from an α‐Stannyl β‐Silylstyrene.
M. Belema, V. Nguyen, F. Zusi
20040 citations
Semantic Scholar
substituted tetracyclic compounds useful as antiinflammatory agents and amino pharmaceutical compositions comprising the same.
F. Beaulieu, M. Belema, Carl Ouellet, Yu-Ping Qiu +2 more
20010 citations
Semantic Scholar
Amino substituted tetracyclic compounds which are useful as anti-inflammatory agents, and medicines containing them
F. Beaulieu, Carl Ouellet, M. Belema, Yu-Ping Qiu +2 more
20010 citations
Semantic Scholar
Amino substituted tetracyclic compounds which are useful as anti-inflammatory agent, and containing the same drug.
F. Beaulieu, Carl Ouellet, M. Belema, Yu-Ping Qiu +2 more
20010 citations
Semantic Scholar
Amino substituierte tetracyclische verbindungen zur anwendung als entzündungsverhütende mittel und diese enthaltende pharmazeutische zubereitungen
F. Beaulieu, M. Belema, Carl Ouellet, Y. Qiu +2 more
20010 citations
Semantic Scholar
Rar gamma-specific retinobenzoic acid derivative
Dan R. Smith, R. Swann, K. Tramposch, F. Zusi +4 more
19960 citations
Semantic Scholar
Means of increasing the transdermal penetration.
Michael D. Helman, Alison B. Lukacsko, T. Re, F. Zusi
19890 citations
Semantic Scholar
A process for the preparation of the 6-aminonicotinic acid-nicotinylesters
Warner, E. Luber, W. Somerville, F. Zusi
19820 citations
Semantic Scholar
A process for preparing nicotinylesteren of 6-aminonicotinic acid
J. P. Warner, J. Luber, W. Somerville, F. Zusi
19820 citations
Semantic Scholar

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