Mendi A. Higgins

Most-cited papers

1. Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.

   G. Poindexter, M. Bruce, J. Breitenbucher, Mendi A. Higgins +8 more

   2004Bioorganic & Medicinal Chemistry59 citations

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2. Synthesis and SAR of indole-and 7-azaindole-1,3-dicarboxamide hydroxyethylamine inhibitors of BACE-1.

   Lawrence R. Marcin, Mendi A. Higgins, F. Zusi, Yun-Hui Zhang +19 more

   2011Bioorganic & Medicinal Chemistry Letters33 citations

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3. Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors.

   R. Mattson, J. D. Catt, D. Denhart, J. Deskus +11 more

   2005Journal of Medicinal Chemistry27 citations Open access

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4. Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists.

   K. Gillman, Mendi A. Higgins, G. Poindexter, M. Browning +11 more

   2006Bioorganic & Medicinal Chemistry20 citations

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5. Identification and Preclinical Evaluation of the Bicyclic Pyrimidine γ-Secretase Modulator BMS-932481

   Kenneth M. Boy, Jason M. Guernon, Dmitry Zuev, Li Xu +25 more

   2019ACS Medicinal Chemistry Letters19 citations Open access

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6. Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor.

   H. King, D. Denhart, J. Deskus, Jonathan L. Ditta +12 more

   2007Bioorganic & Medicinal Chemistry Letters17 citations Open access

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7. Triazolopyridine ethers as potent, orally active mGlu2 positive allosteric modulators for treating schizophrenia.

   Mendi A. Higgins, L. Marcin, F. Zusi, R. Gentles +18 more

   2017Bioorganic & Medicinal Chemistry13 citations Open access

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8. Identification and Preclinical Pharmacology of the γ-Secretase Modulator BMS-869780

   J. Toyn, L. Thompson, K. Lentz, J. Meredith +37 more

   2014International Journal of Alzheimer's Disease13 citations Open access

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9. Discovery of S3-Truncated, C-6 Heteroaryl Substituted Aminothiazine β-Site APP Cleaving Enzyme-1 (BACE1) Inhibitors.

   Yong-Jin Wu, J. Guernon, Jianliang Shi, L. Marcin +11 more

   2016Journal of Medicinal Chemistry11 citations Open access

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10. Synthesis of β-disubstituted β-amino isoxazolyl ketones by addition of ketimines with isoxazolyl methyl ketone enolates

    J. Guernon, L. Marcin, Mendi A. Higgins, Fu-Kang Yang +4 more

    20145 citations

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11. 2-(N-Benzyl-N-phenylsulfonamido)alkyl amide derivatives as γ-secretase inhibitors.

    Michael F. Parker, D. Barten, C. Bergstrom, J. Bronson +13 more

    2012Bioorganic & Medicinal Chemistry Letters4 citations Open access

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12. Synthesis of β‐Disubstituted β‐Amino Isoxazolyl Ketones by Addition of Ketimines with Isoxazolyl Methyl Ketone Enolates.

    J. Guernon, L. Marcin, Mendi A. Higgins, Fu-Kang Yang +4 more

    20140 citations

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