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A. Lewin · SciRah

Researcher profile · Semantic Scholar

A. Lewin

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A. Lewin — researcher profile on SciRah

h-index: 28
Works: 164
Citations: 2,423

Most-cited papers

High‐affinity binding of [125I]RTI‐55 to dopamine and serotonin transporters in rat brain
J. Boja, W. Mitchell, Amrat P. Patel, T. Kopajtic +4 more
1992Synapse213 citations
Semantic Scholar
Designer drugs: a medicinal chemistry perspective
F. Carroll, A. Lewin, S. Mascarella, Herbert H. Seltzman +1 more
2012Annals of the New York Academy of Sciences141 citations
Semantic Scholar
Distribution of carbon‐14 labeled C60 ([14C]C60) in the pregnant and in the lactating dam and the effect of C60 exposure on the biochemical profile of urine
S. Sumner, T. Fennell, Rodney W. Snyder, George F. Taylor +1 more
2010Journal of Applied Toxicology101 citations
Semantic Scholar
Emergence and properties of spice and bath salts: a medicinal chemistry perspective.
A. Lewin, H. Seltzman, F. Carroll, S. Mascarella +1 more
2014Life Science72 citations
Semantic Scholar
Selective labeling of the dopamine transporter by the high affinity ligand 3 beta-(4-[125I]iodophenyl)tropane-2 beta-carboxylic acid isopropyl ester.
J. Boja, J. Cadet, T. A. Kopajtic, J. Lever +5 more
1995Molecular Pharmacology70 citations
Semantic Scholar
Mapping dopamine transporters in the human brain with novel selective cocaine analog [125I]RTI‐121
JK Staley, J. Boja, F. Carroll, H. Seltzman +4 more
1995Synapse70 citations
Semantic Scholar
High specific activity tritium-labeled N-(2-methoxybenzyl)-2,5-dimethoxy-4-iodophenethylamine (INBMeO): a high-affinity 5-HT2A receptor-selective agonist radioligand.
D. E. Nichols, Stewart Frescas, B. Chemel, K. Rehder +2 more
2008Bioorganic & Medicinal Chemistry62 citations Open access
Semantic Scholar
Hydrolytic instability of the important orexin 1 receptor antagonist SB-334867: possible confounding effects on in vivo and in vitro studies.
Charles McElhinny, A. Lewin, S. Mascarella, S. Runyon +2 more
2012Bioorganic & Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
Receptors of mammalian trace amines
A. Lewin
2008AAPS Journal53 citations Open access
Semantic Scholar
Structure-activity correlations for beta-phenethylamines at human trace amine receptor 1.
A. Lewin, H. Navarro, S. Mascarella
2008Bioorganic & Medicinal Chemistry42 citations Open access
Semantic Scholar
Synthesis, Ligand Binding, and Quantitative Structure−Activity Relationship Study of 3β-(4‘-Substituted phenyl)-2β-heterocyclic Tropanes: Evidence for an Electrostatic Interaction at the 2β-Position
P. Kotian, S. Mascarella, P. Abraham, A. Lewin +3 more
199636 citations Open access
Semantic Scholar
Distribution and Biomarker of Carbon-14 Labeled Fullerene C60 ([14C(U)]C60) in Pregnant and Lactating Rats and their Offspring after Maternal Intravenous Exposure
Rodney W. Snyder, T. Fennell, C. Wingard, Ninell P. Mortensen +5 more
2015Journal of Applied Toxicology32 citations Open access
Semantic Scholar
C₆₀ exposure augments cardiac ischemia/reperfusion injury and coronary artery contraction in Sprague Dawley rats.
L. Thompson, Rakhee N Urankar, N. A. Holland, A. Vidanapathirana +8 more
2014Toxicological Sciences32 citations Open access
Semantic Scholar
Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class
A. Lewin, G. Miller, B. Gilmour
2011Bioorganic & Medicinal Chemistry32 citations Open access
Semantic Scholar
A Rapid Functional Assay for the Human Trace Amine-Associated Receptor 1 Based on the Mobilization of Internal Calcium
H. Navarro, B. Gilmour, A. Lewin
2006Journal of biomolecular screening32 citations Open access
Semantic Scholar
Facile synthesis of (±)‐, (+)‐, and (‐)‐galanthamine
J. Szewczyk, Joseph W. Wilson, A. Lewin, F. Carroll
199529 citations
Semantic Scholar
PVP formulated Fullerene (C60) increases Rho-kinase dependent Vascular Tissue Contractility in Pregnant Sprague Dawley Rats
A. Vidanapathirana, L. Thompson, E. Mann, J. Odom +7 more
2014Reproductive Toxicology26 citations Open access
Semantic Scholar
Effects of sphingosine stereoisomers on P-glycoprotein phosphorylation and vinblastine accumulation in multidrug-resistant MCF-7 cells.
C. Sachs, L. Ballas, S. Mascarella, A. Safa +5 more
1996Biochemical Pharmacology26 citations
Semantic Scholar
Molecular features associated with polyamine modulation of NMDA receptors.
A. Lewin, Guobin Sun, Louise Fudala, H. Navarro +4 more
1998Journal of Medicinal Chemistry23 citations
Semantic Scholar
Distribution and biomarkers of Carbon-14 labeled fullerene C60 ([14C(U)]C60) in female rats and mice for up to 30 days after intravenous exposure
S. Sumner, Rodney W. Snyder, C. Wingard, Ninell P. Mortensen +7 more
2015Journal of Applied Toxicology22 citations Open access
Semantic Scholar
Dopamine transporter uptake blockers: Structure-activity relationships
F. Carroll, A. Lewin, S. Mascarella
199522 citations
Semantic Scholar
X-ray structure of Tyr-D-Tic-Phe-Phe-NH2 (D-TIPP-NH2), a highly potent mu-receptor selective opioid agonist. Comparison with proposed model structures.
J. Flippen-Anderson, J. R. Deschamps, Clifford George, P. Reddy +4 more
2009Journal of Peptide Research19 citations
Semantic Scholar
Enamine/imine tautomerism in a,-unsaturated-a-amino acids
Shao-Po Lu, A. Lewin
199819 citations
Semantic Scholar
Synthesis of the 2β,3α- and 2β,3β-isomers of 3-(p-substituted phenyl)tropane-2-carboxylic acid methyl esters
K. I. Keverline, P. Abraham, A. Lewin, F. Carroll
199519 citations
Semantic Scholar
A Practical, Laboratory-ScaleSynthesis of Perampanel
Charles McElhinny, F. Carroll, A. Lewin
201218 citations
Semantic Scholar
Dopamine-Transporter Uptake Blockers
F. Carroll, A. Lewin, S. Mascarella
199717 citations
Semantic Scholar
[3H]1-aminocyclopropanecarboxylic acid, a novel probe for strychnine- insensitive glycine receptors.
P. Popik, A. Lewin, Berthold Berrang, G. Nowak +2 more
1995European Journal of Pharmacology17 citations
Semantic Scholar
Radiosynthesis of a photoaffinity probe for the cocaine receptor of the dopamine transporter : 3β-(p-chlorophenyl)tropan-2β-carboxylic acid m-([125I]-iodo)-p-azidophenethyl ester ([125I]-RTI-82)
J. Lever, F. Carroll, Amrat P. Patel, P. Abraham +3 more
199317 citations
Semantic Scholar
Novel Synthesis and Pharmacological Characterization of NOP Receptor Agonist 8-[(1S,3aS)-2,3,3a,4,5,6-Hexahydro-1H-phenalen-1-yl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one (Ro 64-6198)
Steven D. Chang, Lawrence E. Brieaddy, Joseph D. Harvey, A. Lewin +10 more
2015ACS Chemical Neuroscience14 citations Open access
Semantic Scholar
Identiﬁcation of ( (cid:1) )-Erythro-Meﬂoquine as an Active Enantiomer with Greater Efﬁcacy than Meﬂoquine against Mycobacterium avium Infection in Mice
L. Bermudez, C. Inderlied, P. Kolonoski, Christopher B. Chee +7 more
201212 citations
Semantic Scholar
Evaluation of Retinoids as Therapeutic Agents in Dermatology
A. Lewin, M. E. Bos, F. Zusi, X. Nair +4 more
1994Pharmaceutical Research10 citations
Semantic Scholar
Designer drugs: a medicinal chemistry perspective (II)
F. Carroll, A. Lewin, S. Mascarella, H. Seltzman +1 more
2020Annals of the New York Academy of Sciences9 citations
Semantic Scholar
Molecular mechanics force‐field development for amino acid zwitterions
K. Kirschner, A. Lewin, J. Bowen
2003Journal of Computational Chemistry8 citations
Semantic Scholar
Caged Naloxone: Synthesis, Characterization, and Stability of 3- O-(4,5-Dimethoxy-2-nitrophenyl)carboxymethyl Naloxone (CNV-NLX).
A. Lewin, Scott E. Fix, De-Song Zhong, L. Mayer +5 more
2017ACS Chemical Neuroscience7 citations
Semantic Scholar
Synthesis of Hemopressin Peptides by Classical Solution Phase Fragment Condensation
P. Reddy, Sean T. Jones, A. Lewin, F. Carroll
2012International Journal of Peptides7 citations Open access
Semantic Scholar
Synthesis and Ligand Binding Study of 3β-(4′-Substituted phenyl)- 2β-(heterocyclic)tropanes.
P. Kotian, P. Abraham, A. Lewin, S. Mascarella +3 more
19957 citations
Semantic Scholar
X-ray structures of the δ opioid antagonist TIPP and a protected derivative of the δ opioid antagonist ICI 174,864
J. Flippen-Anderson, C. George, J. R. Deschamps, P. Reddy +2 more
1994Letters in peptide science7 citations
Semantic Scholar
Requirements for high affinity binding of glycine analogs to the glycine site of the NMDA receptor complex.
A. Lewin, P. Skolnick, Juan Carlos Marvizon, I. Paul +1 more
1993European Journal of Pharmacology7 citations
Semantic Scholar
Amiodarone and its Putative Metabolites Fail to Activate Wild Type hTAAR1
A. Lewin, H. Navarro, B. Gilmour
2009Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
3b-(4'-Chlorophenyl)tropan-2b-carboxamides and Cocaine Amide Analogues: New High Affinity and Selective Compounds for the Dopamine Transporter
M. Kuhar, J. Boja, A. Lewin, M. Kuzemko +4 more
19926 citations
Semantic Scholar
Synthesis and Physicochemical Characterization of the One-Carbon Carrier 10-Formyltetrahydrofolate; A Reference Standard for Metabolomics
A. Lewin, P. Silinski, J. Hayes, A. Gilbert +2 more
2017Metabolomics5 citations Open access
Semantic Scholar
Practical Synthesis of p‐Aminophenethylspiperone (NAPS), a High‐Affinity, Selective D2‐Dopamine Receptor Antagonist
Chun-Yang Jin, L. Mayer, A. Lewin, K. Rehder +1 more
20085 citations
Semantic Scholar
An ab initio study of the electrostatics of protonated amines: application to the molecular mechanics (MM3) force field
Jennifer B. Sorensen, A. Lewin, J. Bowen
20035 citations
Semantic Scholar
Synthesis and cocaine receptor affinities of 3-phenyl-2-(3′-methyl-1,2,4-oxadiazole-5′-yl)tropane isomers
F. Carroll, P. Abraham, M. Kuzemko, J. Gray +3 more
19935 citations
Semantic Scholar
High specific activity (+)‐amphetamine and (+)‐methamphetamine
Pamela B. Lamb, Charles McElhinny, Todd Sninski, Hunter Purdom +2 more
20094 citations
Semantic Scholar
Ab initio and molecular mechanics (MM3) calculations of protonated-neutral diamine hydrogen bonds.
Jennifer B. Sorensen, A. Lewin, J. Bowen
2001Journal of Organic Chemistry4 citations
Semantic Scholar
Ab initio calculations and molecular mechanics (MM3) force field development for ammonium and protonated aliphatic amines
G. Liang, Xian-Nong Chen, J. Dustman, A. Lewin +1 more
1997Journal of Computational Chemistry4 citations
Semantic Scholar
Facile Synthesis of (.+-.)-, (+)-, and (-)-Galanthamine.
J. Szewczyk, Joseph W. Wilson, A. Lewin, F. Carroll
19954 citations
Semantic Scholar
One-Step Preparation of [2,3-3H]1-Aminocyclopropanecarboxylic Acid: A Useful Ligand for Strychnine-Insensitive Glycine Receptors
A. Lewin, Pamela B. Lamb, P. Popik, P. Skolnick
19944 citations
Semantic Scholar
Base-catalyzed C-2 exchange and epimerization of cocaine analogs: methyl 3.beta.-substituted 8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylates
J. Casale, A. Lewin, J. Bowen, F. Carroll
19924 citations
Semantic Scholar

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