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Wen-Xing Ding · SciRah

Researcher profile · Semantic Scholar

Wen-Xing Ding

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Wen-Xing Ding — researcher profile on SciRah

h-index: 72
Works: 235
Citations: 24K

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Autophagy in liver diseases: A review
Hui Qian, Xiao-Juan Chao, Jessica A. Williams, S. Fulte +3 more
2021Molecular Aspects of Medicine333 citations Open access
Semantic Scholar
Impaired TFEB-mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-induced Liver Injury and Steatosis in Mice
Xiao-Juan Chao, Shao-Gui Wang, Katrina Zhao, Yuan Li +9 more
2018Gastroenterology320 citations Open access
Semantic Scholar
Role and Mechanisms of Mitophagy in Liver Diseases
Xiao-Wen Ma, Tara McKeen, Jian-Hua Zhang, Wen-Xing Ding
2020Cells259 citations Open access
Semantic Scholar
Role and Mechanisms of Autophagy in Acetaminophen-induced Liver Injury
Xiao-Juan Chao, Hua Wang, H. Jaeschke, Wen-Xing Ding
2018Liver international (Print)145 citations Open access
Semantic Scholar
Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls
H. Jaeschke, Olamide B. Adelusi, J. Akakpo, Nga T Nguyen +4 more
2021Acta Pharmaceutica Sinica B132 citations Open access
Semantic Scholar
EMERGING AND ESTABLISHED MODES OF CELL DEATH DURING ACETAMINOPHEN-INDUCED LIVER INJURY
H. Jaeschke, A. Ramachandran, Xiao-Juan Chao, Wen-Xing Ding
2019Archives of Toxicology123 citations Open access
Semantic Scholar
Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice
Hua Wang, Hong-Min Ni, Xiao-Juan Chao, Xiao-Wen Ma +8 more
2019Redox Biology118 citations Open access
Semantic Scholar
Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation
Xiao-Wen Ma, Allen Chen, Luma Melo, Ana Clemente-Sanchez +11 more
2022Hepatology109 citations Open access
Semantic Scholar
A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery
H. Tan, Guang Lu, Han Dong, Yik-Lam Cho +10 more
2022Nature Communications104 citations Open access
Semantic Scholar
Impaired TFEB-mediated lysosomal biogenesis promotes the development of pancreatitis in mice and is associated with human pancreatitis
Shao-Gui Wang, Hong-Min Ni, Xiao-Juan Chao, Hua Wang +9 more
2019Autophagy104 citations Open access
Semantic Scholar
An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
Yifeng Wang, S. Gunewardena, Feng Li, David J. Matye +8 more
2020Nature Communications93 citations Open access
Semantic Scholar
The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB
Zeyuan Zhang, Q. Qian, Mark Li, Fan Shao +7 more
2020Autophagy88 citations Open access
Semantic Scholar
Delayed Treatment With 4-Methylpyrazole Protects Against Acetaminophen Hepatotoxicity in Mice by Inhibition of c-Jun n-Terminal Kinase.
J. Akakpo, A. Ramachandran, Lu-Qi Duan, M. Schaich +5 more
2019Toxicological Sciences87 citations Open access
Semantic Scholar
Mechanisms, pathophysiological roles and methods for analyzing mitophagy – recent insights
Jessica A. Williams, Wen-Xing Ding
2018Biological chemistry85 citations Open access
Semantic Scholar
Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Xiao Yang, Hua Wang, Hong-Min Ni, Ai-Zhen Xiong +4 more
2017Redox Biology83 citations Open access
Semantic Scholar
PUMA induction mediates acetaminophen-induced necrosis and liver injury
Dongshi Chen, Hong-Min Ni, Lei Wang, Xiao-Wen Ma +3 more
2019Hepatology72 citations Open access
Semantic Scholar
Cholesterol and Bile Acid -Mediated Regulation of Autophagy in Fatty Liver Diseases and Atherosclerosis
Yifeng Wang, Wen-Xing Ding, Tian-Gang Li
2018Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids69 citations Open access
Semantic Scholar
Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)-Mixed Lineage Kinase Domain-Like Protein (MLKL)-Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers.
Hong-Min Ni, Xiao-Juan Chao, Joshua Kaseff, Feng-Yan Deng +5 more
2019American Journal of Pathology68 citations Open access
Semantic Scholar
Autophagy and liver cancer
Xiao-Juan Chao, Hui Qian, Shao-Gui Wang, S. Fulte +1 more
2020Clinical and Molecular Hepatology66 citations Open access
Semantic Scholar
Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy
Xiao-Juan Chao, Shao-Gui Wang, S. Fulte, Xiao-Wen Ma +9 more
2021Journal of Hepatology62 citations Open access
Semantic Scholar
Glutamine synthetase limits β-catenin–mutated liver cancer growth by maintaining nitrogen homeostasis and suppressing mTORC1
Wei-Wei Dai, Jian-Liang Shen, Junrong Yan, Alex J. Bott +13 more
2022Journal of Clinical Investigation60 citations Open access
Semantic Scholar
Mito-Tempo Protects against Acute Liver Injury but Induces Limited Secondary Apoptosis during the Late Phase of Acetaminophen Hepatotoxicity
Kuo Du, A. Ramachandran, James L. Weemhoff, B. Woolbright +4 more
2018Archives of Toxicology59 citations Open access
Semantic Scholar
Lack of VMP1 impairs hepatic lipoprotein secretion and promotes non-alcoholic steatohepatitis
Xiaoxiao Jiang, S. Fulte, Feng-Yan Deng, Shi-Yuan Chen +14 more
2022Journal of Hepatology58 citations Open access
Semantic Scholar
Role of Autophagy in Alcohol and Drug-induced Liver Injury
Jessica A. Williams, Wen-Xing Ding
2019Food and Chemical Toxicology58 citations Open access
Semantic Scholar
Impaired Fasting-Induced Adaptive Lipid Droplet Biogenesis in Liver-Specific Atg5-Deficient Mouse Liver Is Mediated by Persistent Nuclear Factor-Like 2 Activation.
Yuan Li, Xiao-Juan Chao, Li Yang, Qian Lu +3 more
2018American Journal of Pathology58 citations Open access
Semantic Scholar
Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeability
S. Dai, Feng-Ming Liu, Zhong Qin, Jinyan Zhang +5 more
2020Theranostics56 citations Open access
Semantic Scholar
Perspectives on Mitochondria–ER and Mitochondria–Lipid Droplet Contact in Hepatocytes and Hepatic Lipid Metabolism
Xiao-Wen Ma, Hui Qian, Allen Chen, Hong-Min Ni +1 more
2021Cells54 citations Open access
Semantic Scholar
Dual Roles of mTOR in Regulating Liver Injury and Tumorigenesis in Autophagy Defective Mouse Liver
Hong-Min Ni, Xiao-Juan Chao, Hua Yang, Feng-Yan Deng +10 more
2019Hepatology54 citations Open access
Semantic Scholar
Insufficient autophagy: a novel autophagic flux scenario uncovered by impaired liver TFEB-mediated lysosomal biogenesis from chronic alcohol-drinking mice
Xiao-Juan Chao, Hong-Min Ni, Wen-Xing Ding
2018Autophagy52 citations Open access
Semantic Scholar
Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury.
Yifeng Wang, Ji-Biao Li, David J. Matye, Yuxia Zhang +3 more
2018JCI Insight50 citations Open access
Semantic Scholar
Dynamin-1-Like Protein Inhibition Drives Megamitochondria Formation as an Adaptive Response in Alcohol-Induced Hepatotoxicity.
E. Palma, Xiao-Wen Ma, A. Riva, V. Iansante +7 more
2019American Journal of Pathology47 citations Open access
Semantic Scholar
Critical Role of TFEB-Mediated Lysosomal Biogenesis in Alcohol-Induced Pancreatitis in Mice and Humans
Shao-Gui Wang, Hong-Min Ni, Xiao-Juan Chao, Xiao-Wen Ma +5 more
2020Cellular and Molecular Gastroenterology and Hepatology44 citations Open access
Semantic Scholar
Vinyl chloride dysregulates metabolic homeostasis and enhances diet‐induced liver injury in mice
A. Lang, Li-Ya Chen, Gavin D. Poff, Wen-Xing Ding +3 more
2018Hepatology Communications42 citations Open access
Semantic Scholar
Vinyl chloride-induced interaction of nonalcoholic and toxicant-associated steatohepatitis: Protection by the ALDH2 activator Alda-1
Li-Ya Chen, A. Lang, Gavin D. Poff, Wen-Xing Ding +1 more
2019Redox Biology41 citations Open access
Semantic Scholar
Combined ASBT Inhibitor and FGF15 Treatment Improves Therapeutic Efficacy in Experimental Nonalcoholic Steatohepatitis
David J. Matye, Huai-Wen Wang, W. Luo, Rachel R. Sharp +6 more
2021Cellular and Molecular Gastroenterology and Hepatology39 citations Open access
Semantic Scholar
Role and mechanisms of autophagy in alcohol-induced liver injury
Xiao-Juan Chao, Wen-Xing Ding
2019Advances in Pharmacology39 citations Open access
Semantic Scholar
Recent Advances in Understanding the Complexity of Alcohol-Induced Pancreatic Dysfunction and Pancreatitis Development
K. Rasineni, M. Srinivasan, A. Balamurugan, B. Kaphalia +10 more
2020Biomolecules35 citations Open access
Semantic Scholar
Bile Acid–Mediated Activation of Brown Fat Protects From Alcohol-Induced Steatosis and Liver Injury in Mice
M. Fan, Yang-Meng Wang, Lihua Jin, Zhipeng Fang +12 more
2021Cellular and Molecular Gastroenterology and Hepatology34 citations Open access
Semantic Scholar
Loss of acinar cell VMP1 triggers spontaneous pancreatitis in mice
Shao-Gui Wang, Xiao-Juan Chao, Xiaoxiao Jiang, Tian-Tian Wang +5 more
2021Autophagy34 citations Open access
Semantic Scholar
Hepatic Lysosomal iNOS Activity Impairs Autophagy in Obesity
Q. Qian, Zeyuan Zhang, Mark Li, Kalie Savage +8 more
2019Cellular and Molecular Gastroenterology and Hepatology32 citations Open access
Semantic Scholar
Comparative analysis of toxic components in different medicinal parts of Gynura japonica and its toxicity assessment on mice.
Ai-Zhen Xiong, You-Lin Shao, Lian-xiang Fang, X. Yang +5 more
2019Phytomedicine31 citations
Semantic Scholar
Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice
Hui Qian, Qingyun Bai, Xiao Yang, J. Akakpo +7 more
2021Acta Pharmaceutica Sinica B29 citations Open access
Semantic Scholar
The double-edged sword of MTOR in autophagy deficiency induced-liver injury and tumorigenesis
Hua Yang, Hong-Min Ni, Wen-Xing Ding
2019Autophagy28 citations Open access
Semantic Scholar
The role of MLKL in Hepatic Ischemia-Reperfusion Injury of Alcoholic Steatotic Livers
Hao Chen, Tara McKeen, Xiao-Juan Chao, Allen Chen +4 more
2022International Journal on Biological Sciences27 citations Open access
Semantic Scholar
Alcohol and drug-induced liver injury: Metabolism, mechanisms, pathogenesis and potential therapies
Wen-Xing Ding, Li Yang
2019Liver Research27 citations Open access
Semantic Scholar
A fluorescence imaging based-assay to monitor mitophagy in cultured hepatocytes and mouse liver
Xiao-Wen Ma, Wen-Xing Ding
2021Liver Research26 citations Open access
Semantic Scholar
Persistent mTORC1 activation due to loss of liver tuberous sclerosis complex 1 promotes liver injury in alcoholic hepatitis
Xiao-Juan Chao, Shao-Gui Wang, Xiao-Wen Ma, Chen Zhang +10 more
2023Hepatology22 citations
Semantic Scholar
TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis
David J. Matye, S. Gunewardena, Jianglei Chen, Huai-Wen Wang +10 more
2022Nature Communications22 citations Open access
Semantic Scholar
Acute exercise rapidly activates hepatic mitophagic flux.
Colin S. McCoin, Edziu M. Franczak, Feng-Yan Deng, D. Pei +2 more
2022Journal of applied physiology21 citations Open access
Semantic Scholar

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Hong-Min Ni×21
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Jessica A. Williams×4

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A. Ramachandran×4

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