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S. Gunewardena · SciRah

Researcher profile · Semantic Scholar

S. Gunewardena

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S. Gunewardena — researcher profile on SciRah

h-index: 37
Works: 171
Citations: 3,845

Most-cited papers

TEAD4 ensures postimplantation development by promoting trophoblast self-renewal: An implication in early human pregnancy loss
Biswarup Saha, Avishek Ganguly, Pratik Home, B. Bhattacharya +7 more
2020Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
Yifeng Wang, S. Gunewardena, Feng Li, David J. Matye +8 more
2020Nature Communications93 citations Open access
Semantic Scholar
Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration
Ian Huck, S. Gunewardena, Regina Español‐Suñer, H. Willenbring +1 more
2019Hepatology84 citations Open access
Semantic Scholar
The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice
Prasad Dandawate, Chandrayee Ghosh, Kanagaraj Palaniyandi, Santanu Paul +18 more
2019Gastroenterology70 citations Open access
Semantic Scholar
Progressive loss of HNF4α activity in chronic liver diseases in humans
S. Gunewardena, Ian Huck, Chad M. Walesky, Dakota R. Robarts +2 more
2022Hepatology49 citations Open access
Semantic Scholar
A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver
Heng Wu, Tzachi Reizel, Y. Wang, Jessica Lapiro +16 more
2020Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Metastatic Tumor-In-A-Dish, A Novel Multi-Cellular Organoid To Study Lung Colonization and Predict Therapeutic Response
P. Ramamoorthy, S. Thomas, Gaurav Kaushik, D. Subramaniam +14 more
2019Cancer Research46 citations Open access
Semantic Scholar
A Western diet with alcohol in drinking water model recapitulates features of alcohol-associated liver disease in mice
Michael Schonfeld, M. O'Neil, M. T. Villar, A. Artigues +4 more
2021Alcoholism: Clinical and Experimental Research38 citations Open access
Semantic Scholar
Hippo signaling cofactor, WWTR1, at the crossroads of human trophoblast progenitor self-renewal and differentiation
S. Ray, A. Saha, Ananya Ghosh, Namrata Roy +7 more
2022bioRxiv37 citations Open access
Semantic Scholar
CCN5 activation by free or encapsulated EGCG is required to render triple‐negative breast cancer cell viability and tumor progression
Amlan Das, I. Haque, Priyanka Ray, Arnab Ghosh +8 more
2021Pharmacology Research & Perspectives36 citations Open access
Semantic Scholar
Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro
Xiaoyu Zhang, S. Gunewardena, Ning Wang
2021Nature Communications34 citations Open access
Semantic Scholar
Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression
Olivia K. Provance, Eric S. Geanes, Asona J. Lui, Anuradha Roy +5 more
2021Cancer Letters34 citations Open access
Semantic Scholar
CYR61/CCN1 Regulates dCK and CTGF and Causes Gemcitabine-resistant Phenotype in Pancreatic Ductal Adenocarcinoma
G. Maity, Arnab Ghosh, V. Gupta, I. Haque +10 more
2019Molecular Cancer Therapeutics32 citations
Semantic Scholar
Kupffer cell diversity maintains liver function in alcohol-associated liver disease
Kyo Sasaki, Sheetalnath Rooge, S. Gunewardena, Janice Averilla Hintz +11 more
2024Hepatology27 citations
Semantic Scholar
Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in Mice
Dakota R. Robarts, Steven R. McGreal, David S. Umbaugh, Wendena S Parkes +10 more
2021bioRxiv27 citations Open access
Semantic Scholar
GenX Induces Fibroinflammatory Gene Expression in Primary Human Hepatocytes
Dakota R. Robarts, Kaitlyn K. Venneman, S. Gunewardena, U. Apte
2022Toxicology26 citations Open access
Semantic Scholar
RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways
Andrew S. Welleford, J. Quintero, N. El-Seblani, E. Blalock +8 more
2020Cell Transplantation24 citations Open access
Semantic Scholar
Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal–fetal exchange interface
B. Bhattacharya, Pratik Home, Avishek Ganguly, S. Ray +8 more
2019Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Sera of Individuals Chronically Infected with Hepatitis B Virus (HBV) Contain Diverse RNA Types Produced by HBV Replication or Derived from Integrated HBV DNA
Igor Zaiets, S. Gunewardena, S. Menne, S. Weinman +1 more
2023Journal of Virology22 citations
Semantic Scholar
TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis
David J. Matye, S. Gunewardena, Jianglei Chen, Huai-Wen Wang +10 more
2022Nature Communications22 citations Open access
Semantic Scholar
Super-enhancers: novel target for pancreatic ductal adenocarcinoma
Chandrayee Ghosh, Santanu Paul, Prasad Dandawate, S. Gunewardena +4 more
2019OncoTarget22 citations Open access
Semantic Scholar
Identifying novel mechanisms of per- and polyfluoroalkyl substance-induced hepatotoxicity using FRG humanized mice
Dakota R. Robarts, Diego Paine-Cabrera, Manasi Kotulkar, Kaitlyn K. Venneman +4 more
2024Archives of Toxicology21 citations
Semantic Scholar
Exploring Whether Iron Sequestration within the CNS of Patients with Alzheimer’s Disease Causes a Functional Iron Deficiency That Advances Neurodegeneration
S. LeVine, S. Tsau, S. Gunewardena
2023Brain Science20 citations Open access
Semantic Scholar
Male‐Specific Activation of Lysine Demethylases 5B and 5C Mediates Alcohol‐Induced Liver Injury and Hepatocyte Dedifferentiation
Michael Schonfeld, Janice Averilla, S. Gunewardena, S. Weinman +1 more
2022Hepatology Communications19 citations Open access
Semantic Scholar
Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice.
Jie Liu, S. Gunewardena, Julia Yue Cui, C. Klaassen +2 more
2020Toxicology19 citations Open access
Semantic Scholar
Loss of the repressor REST affects progesterone receptor function and promotes uterine leiomyoma pathogenesis
A. Cloud, F. Koohestani, M. McWilliams, Sornakala Ganeshkumar +4 more
2022bioRxiv18 citations Open access
Semantic Scholar
The START domain mediates Arabidopsis GLABRA2 dimerization and turnover independently of homeodomain DNA binding.
Thiya Mukherjee, Bibek Subedi, Aashima Khosla, Erika M. Begler +6 more
2022Plant Physiology18 citations Open access
Semantic Scholar
Alcohol‐associated fibrosis in females is mediated by female‐specific activation of lysine demethylases KDM5B and KDM5C
Michael Schonfeld, Janice Averilla, S. Gunewardena, S. Weinman +1 more
2022Hepatology Communications17 citations Open access
Semantic Scholar
Comparison of Liver Regeneration after Partial Hepatectomy and Acetaminophen-induced Acute Liver Failure: A Global Picture Based on Transcriptome Analysis
Bharat Bhushan, S. Gunewardena, Genea Edwards, U. Apte
2020Food and Chemical Toxicology17 citations Open access
Semantic Scholar
Landscape of Double-Stranded DNA Breaks in Postmortem Brains from Alzheimer’s Disease and Non-Demented Individuals
Xiaoyu Zhang, Yan Liu, Ming-lie Huang, S. Gunewardena +3 more
2023Journal of Alzheimer's Disease16 citations Open access
Semantic Scholar
Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs†
Pavla Brachova, Nehemiah S. Alvarez, X. Hong, S. Gunewardena +3 more
2019Biology of Reproduction16 citations Open access
Semantic Scholar
Pleotropic role of RNA binding protein CELF2 in Autophagy Induction
Jacob New, D. Subramaniam, S. Ramalingam, J. Enders +12 more
2019Molecular Carcinogenesis16 citations Open access
Semantic Scholar
Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells
M. Chinnappan, S. Gunewardena, Prabhakar Chalise, N. Dhillon
2019Scientific Reports16 citations Open access
Semantic Scholar
Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
Xiaoyu Zhang, Yan Liu, F. Sosa, S. Gunewardena +4 more
2023Cell Reports15 citations Open access
Semantic Scholar
Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families
Isaac Baldwin, Robin L. Shafer, W. Hossain, S. Gunewardena +3 more
2021International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
Modulation of β-Catenin promotes WNT expression in macrophages and mitigates intestinal injury
R. Chugh, P. Bhanja, Ryan C. Zitter, S. Gunewardena +2 more
2025Cell Communication and Signaling13 citations
Semantic Scholar
Heat-induced increases in body temperature in lactating dairy cows: impact on the cumulus and granulosa cell transcriptome of the periovulatory follicle.
J. L. Klabnik, L. Christenson, S. Gunewardena, K. Pohler +5 more
2022Journal of Animal Science13 citations Open access
Semantic Scholar
Abstract P5-04-05: Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression
Aditya M. Vargheese, A. Cloud, S. Gunewardena, Raeann M. Shimak +4 more
2022Cancer Research12 citations
Semantic Scholar
Hepatocyte Specific Deletion of Yes-Associated Protein (YAP) Improves Recovery from Acetaminophen-Induced Acute Liver Injury.
Samikshya Poudel, Diego Paine-Cabrera, Bharat Bhushan, Michael W. Manley +3 more
2021Toxicological Sciences12 citations Open access
Semantic Scholar
Anti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity
Syed K. Rafi, J. Goering, Adam J. Olm-Shipman, Lauren Hipp +5 more
2021PLoS ONE12 citations Open access
Semantic Scholar
Loss of REST in breast cancer promotes tumor progression through estrogen sensitization, MMP24 and CEMIP overexpression
A. Cloud, Aditya M. Vargheese, S. Gunewardena, Raeann M. Shimak +4 more
2021BMC Cancer11 citations Open access
Semantic Scholar
Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma
D. Standing, Levi Arnold, Prasad Dandawate, Brendan M. Ottemann +22 more
2022bioRxiv10 citations Open access
Semantic Scholar
TRIM16 mediates secretory autophagy in head and neck cancer-associated fibroblasts
Thuc Ly, Bailey Pickard, Avisha Pandey, Marrion Yap +15 more
2025Autophagy8 citations
Semantic Scholar
Resistance exercise in early-stage ALS patients, ALSFRS-R, Sickness Impact Profile ALS-19, and muscle transcriptome: a pilot study
O. Jawdat, Jason L. Rucker, Tomoki Nakano, Kotaro Takeno +13 more
2024Scientific Reports8 citations Open access
Semantic Scholar
Uterine cyclin A2–deficient mice as a model of female early pregnancy loss
Fatimah Aljubran, K. Schumacher, Amanda R. Graham, S. Gunewardena +4 more
2024Journal of Clinical Investigation8 citations Open access
Semantic Scholar
Identification of follicle‐stimulating hormone‐responsive genes in Sertoli cells during early postnatal mouse testis development
Hui-Zhen Wang, Z. Liu, M. Larsen, R. Hastings +2 more
2023Andrology7 citations
Semantic Scholar
Histone lysine demethylase 4B regulates general and unique gene expression signatures in hypoxic cancer cells
L. Qiu, Yang Meng, Ling-Li Wang, S. Gunewardena +3 more
2021MedComm7 citations Open access
Semantic Scholar
Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8‐DNA interactions and effectively inhibits prostate tumor growth in mice
Dev Karan, S. Dubey, S. Gunewardena, Kenneth A. Iczkowski +6 more
2024Molecular Oncology6 citations Open access
Semantic Scholar
Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett’s like metaplasia
A. De, Jian-Ping Zhou, Pi Liu, Manling Huang +6 more
2021Laboratory Investigation6 citations Open access
Semantic Scholar
Selective targeting of IRAK1 attenuates low molecular weight hyaluronic acid-induced stemness and non-canonical STAT3 activation in epithelial ovarian cancer
D. Standing, Prasad Dandawate, S. Gunewardena, O. Covarrubias-Zambrano +9 more
2024Cell Death and Disease5 citations Open access
Semantic Scholar

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