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Jianglei Chen · SciRah

Researcher profile · Semantic Scholar

Jianglei Chen

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Jianglei Chen — researcher profile on SciRah

h-index: 15
Works: 36
Citations: 874

Most-cited papers

Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions
Jianglei Chen, Qian-Qian Li, Jian-Jun Wang
2011Proceedings of the National Academy of Sciences of the United States of America265 citations Open access
Semantic Scholar
Mesd binds to mature LDL-receptor-related protein-6 and antagonizes ligand binding
Yong-He Li, Jianglei Chen, Wenyan Lu, L. Mccormick +2 more
2005Journal of Cell Science57 citations Open access
Semantic Scholar
miRNA-451a regulates RPE function through promoting mitochondrial function in proliferative diabetic retinopathy.
Y. Shao, Li-Jie Dong, Y. Takahashi, Jianglei Chen +4 more
2019American Journal of Physiology. Endocrinology and Metabolism53 citations Open access
Semantic Scholar
Anti-aging Gene Klotho Deficiency Promoted High Fat Diet-induced Arterial Stiffening via Inactivation of AMP-activated Protein Kinase
Yi Lin, Jianglei Chen, Zhongjie Sun
2016HYPERTENSION52 citations Open access
Semantic Scholar
Elimination of in vivo cleavage between target protein and intein in the intein-mediated protein purification systems.
Chunxian Cui, Wentao Zhao, Jianglei Chen, Jian-Jun Wang +1 more
2006Protein Expression and Purification52 citations
Semantic Scholar
Deficiency in the anti‐aging gene Klotho promotes aortic valve fibrosis through AMPKα‐mediated activation of RUNX2
Jianglei Chen, Yi Lin, Zhongjie Sun
2016Aging Cell47 citations Open access
Semantic Scholar
A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism
Y. Shao, Jianglei Chen, Li-Jie Dong, Xuemin He +6 more
2019Diabetes45 citations Open access
Semantic Scholar
Secreted Klotho Attenuated Inflammation-Associated Aortic Valve Fibrosis in Senescence Accelerated Mice P1 (SAMP1)
Jianglei Chen, Jun Fan, Shirley Wang, Zhongjie Sun
2018HYPERTENSION40 citations Open access
Semantic Scholar
Pathogenic role of human C-reactive protein in diabetic retinopathy.
F. Qiu, Xiang Ma, Younghwa Shin, Jianglei Chen +7 more
2020Clinical science35 citations Open access
Semantic Scholar
Canonical Wnt Signaling Promotes Neovascularization Through Determination of Endothelial Progenitor Cell Fate via Metabolic Profile Regulation
Y. Shao, Jianglei Chen, W. Freeman, Li-Jie Dong +7 more
2019Stem Cells27 citations Open access
Semantic Scholar
Interphotoreceptor Retinol-Binding Protein Ameliorates Diabetes-Induced Retinal Dysfunction and Neurodegeneration Through Rhodopsin
Ada Admin, Jianglei Chen, Y. Shao, Temmy Sasore +5 more
2020Diabetes23 citations Open access
Semantic Scholar
TFEB regulates sulfur amino acid and coenzyme A metabolism to support hepatic metabolic adaptation and redox homeostasis
David J. Matye, S. Gunewardena, Jianglei Chen, Huai-Wen Wang +10 more
2022Nature Communications22 citations Open access
Semantic Scholar
Two Structural and Functional Domains of MESD Required for Proper Folding and Trafficking of LRP5/6
Jianglei Chen, Chia-Chen Liu, Qian-Qian Li, Christian Nowak +2 more
2011Structure20 citations Open access
Semantic Scholar
Inhibition of miR-101-3p prevents human aortic valve interstitial cell calcification through regulation of CDH11/SOX9 expression
Jianglei Chen, Yi Lin, Zhongjie Sun
2023Molecular Medicine16 citations Open access
Semantic Scholar
A novel bacterial expression method with optimized parameters for very high yield production of triple-labeled proteins.
Victoria L. Murray, Yuefei Huang, Jianglei Chen, Jian-Jun Wang +1 more
2012Methods in molecular biology16 citations
Semantic Scholar
Combining ASBT inhibitor and FGF15 treatments enhances therapeutic efficacy against cholangiopathy in female but not male Cyp2c70 KO mice
M. N. Hasan, Jianglei Chen, David J. Matye, Huai-Wen Wang +5 more
2023Journal of Lipid Research15 citations Open access
Semantic Scholar
A complete backbone spectral assignment of lipid-free human apolipoprotein E (apoE)
Yonghong Zhang, Jianglei Chen, Jian-Jun Wang
2008Biomolecular NMR Assignments14 citations
Semantic Scholar
Glycine-β-Muricholic Acid Improves Liver Fibrosis and Gut Barrier Function by Reducing Bile Acid Pool Size and Hydrophobicity in Male Cyp2c70 Knockout Mice
M. N. Hasan, Jianglei Chen, Huai-Wen Wang, Yan-Hong Du +3 more
2023Cells11 citations Open access
Semantic Scholar
Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration
Xiang Ma, Y. Takahashi, Wenjing Wu, Jianglei Chen +5 more
2021The FASEB Journal11 citations Open access
Semantic Scholar
ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium
Xiang Ma, Y. Takahashi, Wenjing Wu, W. Liang +6 more
2021Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Real time investigation of protein folding, structure, and dynamics in living cells.
Qian-Qian Li, Yuefei Huang, Nan Xiao, Victoria L. Murray +2 more
2008Methods in Cell Biology10 citations
Semantic Scholar
A segmental labeling strategy for unambiguous determination of domain–domain interactions of large multi-domain proteins
Jianglei Chen, Jian-Jun Wang
2011Journal of Biomolecular NMR9 citations
Semantic Scholar
Preparation of very-high-yield recombinant proteins using novel high-cell-density bacterial expression methods.
Victoria L. Murray, Jianglei Chen, Yuefei Huang, Qian-Qian Li +1 more
2010Cold Spring Harbor Protocols9 citations
Semantic Scholar
The Single Administration of a Chromophore Alleviates Neural Defects in Diabetic Retinopathy.
Volha V. Malechka, Jianglei Chen, R. Cheng, Jian-Xing Ma +1 more
2020American Journal of Pathology7 citations Open access
Semantic Scholar
NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6
Jianglei Chen, Qian-Qian Li, Chia-Chen Liu, Bei Zhou +2 more
2010Journal of Biomolecular NMR5 citations
Semantic Scholar
Detection and Quantification of Retinal Neovascularization Using BrdU Incorporation
Y. Shao, Jianglei Chen, Xiao-Rong Li, Jian-Xing Ma
2020Translational Vision Science & Technology1 citations Open access
Semantic Scholar
Monomeric Mouse ApoAI(1-216)
Jianglei Chen, Jian-Jun Wang, Yun-Huang Yang
20121 citations
Semantic Scholar
Structural and functional studies of MESD, a specialized chaperone protein of LRP5/6 in Wnt signaling
Jianglei Chen
20091 citations
Semantic Scholar
Inhibition of miR‐101‐3p Prevents Human Aortic Valve Interstitial Cells Calcification through Regulation of CDH11/Sox9 Expression
Jianglei Chen, Yi Lin, Zhongjie Sun
20180 citations
Semantic Scholar
Kidney‐specific Conditional Knockout of Klotho Gene Impairs Natriuresis and causes hypertension by upregulating Epithelial Sodium Channel alpha
Q. Ali, Yi Lin, Shirley Wang, Kai Chen +2 more
2017The FASEB Journal0 citations Open access
Semantic Scholar
Abstract 40: Investigation into Heart Aging
Kai Chen, Shirley Wang, Jianglei Chen, W. Sun +2 more
2017Circulation Research0 citations
Semantic Scholar
Abstract 15931: Fighting CAVD: Secreted Klotho Protects Osteoclastogenesis via Regulation of Canonical NF-κB (P65) Pathway and RANK-RANKL/OPG Axis
Jianglei Chen, Kai Chen, Yi Lin, Zhongjie Sun
20170 citations
Semantic Scholar
Deficiency in the Anti‐Aging Gene Klotho Promotes Aortic Valve Fibrosis through AMPKα‐mediated Activation of RUNX2
Jianglei Chen, Yi Lin, Zhongjie Sun
2016The FASEB Journal0 citations Open access
Semantic Scholar
Compound H Increases Anti‐aging Protein Klotho Expression and Attenuates Arterial Stiffening and Hypertension
Kai Chen, Jianglei Chen, Zhongjie Sun
20150 citations
Semantic Scholar
Erratum to: NMR structure note: solution structure of the core domain of MESD that is essential for proper folding of LRP5/6
Jianglei Chen, Qian-Qian Li, Chia-Chen Liu, Pei Zhou +2 more
20110 citations Open access
Semantic Scholar
A complete NMR spectral assignment of the conserved region of the MESD protein, MESD(12-155)
Jianglei Chen, Guo-Jun Bu, Jian-Jun Wang
2007Biomolecular NMR Assignments0 citations
Semantic Scholar

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