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J. Seligmann · SciRah

Researcher profile · Semantic Scholar

J. Seligmann

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J. Seligmann — researcher profile on SciRah

h-index: 21
Works: 112
Citations: 3,830

Most-cited papers

Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up†.
A. Cervantes, R. Adam, S. Roselló, D. Arnold +7 more
2022Annals of Oncology1,624 citations Open access
Semantic Scholar
Preoperative Chemotherapy for Operable Colon Cancer: Mature Results of an International Randomized Controlled Trial
D. Morton, M. Seymour, L. Magill, K. Handley +9 more
2023Journal of Clinical Oncology328 citations Open access
Semantic Scholar
Investigating the poor outcomes of BRAF-mutant advanced colorectal cancer: analysis from 2530 patients in randomised clinical trials
J. Seligmann, D. Fisher, Christopher Smith, S. Richman +8 more
2016Annals of Oncology165 citations Open access
Semantic Scholar
Combined Epiregulin and Amphiregulin Expression Levels as a Predictive Biomarker for Panitumumab Therapy Benefit or Lack of Benefit in Patients With RAS Wild-Type Advanced Colorectal Cancer.
J. Seligmann, F. Elliott, S. Richman, B. Jacobs +6 more
2016JAMA Oncology105 citations Open access
Semantic Scholar
Neoadjuvant immunotherapy for dMMR and pMMR colorectal cancers: therapeutic strategies and putative biomarkers of response
C. Williams, Allyson M. Peddle, P. Kasi, J. Seligmann +3 more
2024Nature Reviews Clinical Oncology94 citations
Semantic Scholar
Inhibition of WEE1 Is Effective in TP53- and RAS-Mutant Metastatic Colorectal Cancer: A Randomized Trial (FOCUS4-C) Comparing Adavosertib (AZD1775) With Active Monitoring
J. Seligmann, D. Fisher, L. Brown, R. Adams +18 more
2021Journal of Clinical Oncology91 citations Open access
Semantic Scholar
Epidemiology, pathogenesis, biology and evolving management of MSI-H/dMMR cancers
M. Ambrosini, P. Manca, V. Nasca, Carolina Sciortino +4 more
2025Nature Reviews Clinical Oncology77 citations
Semantic Scholar
The Evolving Biomarker Landscape for Treatment Selection in Metastatic Colorectal Cancer
J. Taieb, A. Jung, A. Sartore-Bianchi, M. Peeters +5 more
2019Drugs69 citations Open access
Semantic Scholar
Metastatic colorectal cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.
C. Cremolini, M. Chalabi, E. Élez, M. Fassan +11 more
2026Annals of Oncology53 citations
Semantic Scholar
Inhibition of EGFR, HER2, and HER3 signalling in patients with colorectal cancer wild-type for BRAF, PIK3CA, KRAS, and NRAS (FOCUS4-D): a phase 2–3 randomised trial
R. Adams, E. Brown, L. Brown, R. Butler +12 more
2017The Lancet Gastroenterology and Hepatology45 citations Open access
Semantic Scholar
Responding to Acute Care Needs of Patients With Cancer: Recent Trends Across Continents.
A. Young, E. Marshall, M. Krzyzanowska, B. Robinson +8 more
2016The Oncologist43 citations Open access
Semantic Scholar
NEOPRISM-CRC: Neoadjuvant pembrolizumab stratified to tumour mutation burden for high risk stage 2 or stage 3 deficient-MMR/MSI-high colorectal cancer.
K. Shiu, Yan-Rong Jiang, M. Saunders, J. Seligmann +14 more
2024Journal of Clinical Oncology35 citations
Semantic Scholar
EORTC consensus recommendations on the optimal management of colorectal cancer liver metastases.
G. Bregni, Richard A. Adams, R. Bale, M. Bali +47 more
2025Cancer Treatment Reviews30 citations Open access
Semantic Scholar
FOxTROT: neoadjuvant FOLFOX chemotherapy with or without panitumumab (Pan) for patients (pts) with locally advanced colon cancer (CC).
J. Seligmann
202027 citations
Semantic Scholar
Capecitabine Versus Active Monitoring in Stable or Responding Metastatic Colorectal Cancer After 16 Weeks of First-Line Therapy: Results of the Randomized FOCUS4-N Trial
R. Adams, D. Fisher, J. Graham, J. Seligmann +17 more
2021Journal of Clinical Oncology26 citations Open access
Semantic Scholar
Making an IMPACT: A priority setting consultation exercise to improve outcomes in patients with locally advanced, recurrent and metastatic colorectal cancer.
A. Vallance, D. Harji, N. Fearnhead, A. Acheson +105 more
2019European Journal of Surgical Oncology23 citations Open access
Semantic Scholar
Molecular subtype-specific efficacy of anti-EGFR therapy in colorectal cancer is dependent on the chemotherapy backbone
S. ten Hoorn, D. Sommeijer, F. Elliott, D. Fisher +11 more
2021British Journal of Cancer22 citations Open access
Semantic Scholar
EGFR Amplification in Metastatic Colorectal Cancer.
G. Randon, R. Yaeger, J. Hechtman, P. Manca +22 more
2021Journal of the National Cancer Institute22 citations Open access
Semantic Scholar
Association of Tumor HER3 Messenger RNA Expression With Panitumumab Efficacy in Advanced Colorectal Cancer
J. Seligmann, A. Hatch, S. Richman, F. Elliott +7 more
2017JAMA Oncology21 citations Open access
Semantic Scholar
Risk of bowel obstruction in patients with colon cancer responding to immunotherapy: an international case series
J. Platt, J. Allotey, E. Alouani, J. Glasbey +17 more
2024ESMO Open20 citations Open access
Semantic Scholar
Evaluation of CD3 and CD8 T-Cell Immunohistochemistry for Prognostication and Prediction of Benefit From Adjuvant Chemotherapy in Early-Stage Colorectal Cancer Within the QUASAR Trial
C. Williams, Richard Gray, R. Hills, M. Shires +21 more
2024Journal of Clinical Oncology20 citations Open access
Semantic Scholar
The impact of mismatch repair status and systemic inflammatory markers on radiological staging in colon cancer
J. Platt, Jennifer Ansett, J. Seligmann, N. West +1 more
2023British Journal of Radiology19 citations Open access
Semantic Scholar
Associations between AI-Assisted Tumor Amphiregulin and Epiregulin IHC and Outcomes from Anti-EGFR Therapy in the Routine Management of Metastatic Colorectal Cancer
C. Williams, F. Elliott, Nancy Sapanara, Faranak Aghaei +50 more
2023Clinical Cancer Research18 citations Open access
Semantic Scholar
Clinical and molecular characteristics and treatment outcomes of advanced right-colon, left-colon and rectal cancers: data from 1180 patients in a phase III trial of panitumumab with an extended biomarker panel.
J. Seligmann, F. Elliott, S. Richman, G. Hemmings +7 more
2020Annals of Oncology17 citations Open access
Semantic Scholar
Personalizing neoadjuvant chemotherapy for locally advanced colon cancer: protocols for the international phase III FOxTROT2 and FOxTROT3 randomized controlled trials
J. Platt, C. Williams, Z. Craig, D. Cairns +3 more
2023Colorectal Disease16 citations Open access
Semantic Scholar
Addressing the variation in adjuvant chemotherapy treatment for colorectal cancer: Can a regional intervention promote national change?
John C. Taylor, D. Swinson, J. Seligmann, Rebecca J. Birch +6 more
2020International Journal of Cancer16 citations Open access
Semantic Scholar
Durvalumab and tremelimumab plus local partial tumour ablation (radiofrequency ablation or stereotactic radiotherapy) in patients with unresectable liver metastases from metastatic colorectal cancer: results of the EORTC-1560-GITCG multicentre, single-arm phase II study (ILOC)
J. Seligmann, T. Koessler, M. Mauer, S. Evrard +12 more
2025ESMO Open14 citations Open access
Semantic Scholar
Incorporating neoadjuvant chemotherapy into locally advanced colon cancer treatment pathways: Real‐life experience of implementing FOxTROT
C. Williams, R. Fish, Lucy Akerman, N. West +3 more
2022Colorectal Disease14 citations Open access
Semantic Scholar
Lapatinib plus Capecitabine versus Trastuzumab plus Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer with Central Nervous System Metastases for Patients Currently or Previously Treated with Trastuzumab (LANTERN): a Phase II Randomised Trial.
J. Seligmann, A. Wright-Hughes, A. Pottinger, G. Velikova +9 more
2020Clinics in oncology14 citations
Semantic Scholar
Neo-adjuvant FOLFOX with and without panitumumab for patients with KRAS-wt locally advanced colon cancer: results following an extended biomarker panel on the FOxTROT Trial embedded phase II population.
J. Seligmann, D. Morton, F. Elliott, K. Handley +11 more
2025Annals of Oncology13 citations Open access
Semantic Scholar
Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer
L. Brown, J. Graham, D. Fisher, R. Adams +13 more
2022Clinical Trials13 citations Open access
Semantic Scholar
Is age a barrier to chemotherapy? Rates of treatment in older patients with breast, colon or lung cancer in England in 2014: A national registry study.
N. Battisti, M. Wallington, A. Ring, S. Payne +11 more
2018Annals of Oncology13 citations Open access
Semantic Scholar
Exploring the poor outcomes of BRAF mutant (BRAF mut) advanced colorectal cancer (aCRC): Analysis from 2,530 patients (pts) in randomized clinical trials (RCTs).
J. Seligmann, D. Fisher, F. Elliott, S. Richman +7 more
201513 citations
Semantic Scholar
A Phase II trial of Higher RadiOtherapy Dose In The Eradication of early rectal cancer (APHRODITE): protocol for a multicentre, open-label randomised controlled trial
E. Hudson, S. Noutch, S. Brown, Ravi Adapala +18 more
2022BMJ Open12 citations Open access
Semantic Scholar
Artificial Intelligence–Assisted Amphiregulin and Epiregulin IHC Predicts Panitumumab Benefit in RAS Wild-Type Metastatic Colorectal Cancer
C. Williams, J. Seligmann, F. Elliott, M. Shires +23 more
2021Clinical Cancer Research12 citations
Semantic Scholar
CT staging performance in an international trial of neoadjuvant chemotherapy for locally advanced colon cancer
J. R. Platt, Faye Elliott, K. Handley, L. Magill +6 more
2025British Journal of Radiology11 citations Open access
Semantic Scholar
A Phase III study of perioperative dostarlimab in patients with dMMR/MSI-H resectable colon cancer: AZUR-2 study design
N. Starling, E. Élez, J. Strickler, Al B. Benson +11 more
2026Future Oncology9 citations Open access
Semantic Scholar
AZUR-2, a phase III, open-label, randomized study of perioperative dostarlimab monotherapy vs standard of care in previously untreated patients with T4N0 or stage III dMMR/MSI-H resectable colon cancer.
N. Starling, Katerina Neumann, Bruce Colwell, J. Strickler +8 more
2024Journal of Clinical Oncology9 citations
Semantic Scholar
FOxTROT2: innovative trial design to evaluate the role of neoadjuvant chemotherapy for treating locally advanced colon cancer in older adults or those with frailty
J. R. Platt, O. Todd, P. Hall, Z. Craig +13 more
2022ESMO Open9 citations Open access
Semantic Scholar
Colorectal cancer peritoneal metastases: Biology, treatment and next steps.
Ilona C P A Baaten, N. West, A. Quyn, M. Seymour +1 more
2019European Journal of Surgical Oncology9 citations Open access
Semantic Scholar
Colon cancer biology and treatment in the era of precision oncology: A primer for Radiologists.
J. Platt, S. Pennycook, Chand E. Muthoo, A. Westwood +5 more
2025European Journal of Radiology8 citations Open access
Semantic Scholar
A biomarker enrichment trial of anti-EGFR agents in right primary tumor location (rPTL), RAS wild-type (RAS-wt) advanced colorectal cancer (aCRC): ARIEL (ISRCTN11061442).
C. Williams, J. Emmerson, A. Beggs, N. West +11 more
2022Journal of Clinical Oncology8 citations Open access
Semantic Scholar
Targeting the MAP kinase pathway in colorectal cancer: A journey in personalized medicine
Jordan W. Appleyard, C. Williams, P. Manca, F. Pietrantonio +1 more
2025Clinical Cancer Research6 citations Open access
Semantic Scholar
552O FOxTROT: Results of embedded phase II evaluating the addition of panitumumab (pan) to neo-adjuvant FOLFOX for patients (pts) with KRAS-wt colon cancer (CC) with extended biomarker panel
J. Seligmann, D. Morton, M. Seymour, F. Elliott +10 more
2023Annals of Oncology6 citations Open access
Semantic Scholar
389MO Risk of bowel obstruction in patients undergoing neoadjuvant chemotherapy for high-risk colon cancer: A nested case-control matched analysis of an international, multi-centre, randomised controlled trial (FOxTROT)
J. Glasbey, J. Seligmann, D. Morton, The FOxTROT Collaborating Group
2021Annals of Oncology6 citations Open access
Semantic Scholar
Combined epiregulin (EREG) and amphiregulin (AREG) expression levels as a biomarker of prognosis and panitumumab benefit in RAS-wt advanced colorectal cancer (aCRC).
J. Seligmann, F. Elliott, S. Richman, B. Jacobs +5 more
20146 citations
Semantic Scholar
Colorectal cancer staging-time for a re-think on TNM?
J. Seligmann
2025British Journal of Surgery5 citations
Semantic Scholar
Promoting large multinational academic clinical trials for gastrointestinal cancers in Europe: the ENGIC (European Network for GI Cancers) initiative
J. Taieb, J. Seligmann, D. Modest, C. Girault +153 more
2025ESMO Open4 citations Open access
Semantic Scholar
552P Baseline imaging biomarkers to predict outcomes in locally advanced colon cancer (LACC): Data from the FOxTROT international randomised-controlled trial
J. R. Platt, F. Elliott, P. Quirke, N. West +6 more
2024Annals of Oncology4 citations
Semantic Scholar
Standardizing data collection in adjuvant colon cancer trials: A consensus project from the IDEA and ACCENT international consortia and national experts.
J. Taieb, D. Basile, J. Seligmann, G. Argilés +17 more
2024European Journal of Cancer4 citations Open access
Semantic Scholar

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J. Barrett — researcher profile on SciRah

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E. Élez — researcher profile on SciRah