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M. Peggie · SciRah

Researcher profile · Semantic Scholar

M. Peggie

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M. Peggie — researcher profile on SciRah

h-index: 45
Works: 81
Citations: 7,935

Most-cited papers

The ancient drug salicylate directly activates AMP-activated protein kinase
Simon A. Hawley, M. Fullerton, Fiona A. Ross, J. Schertzer +10 more
2012Science768 citations Open access
Semantic Scholar
Chaperoned ubiquitylation--crystal structures of the CHIP U box E3 ubiquitin ligase and a CHIP-Ubc13-Uev1a complex.
Ming-Hao Zhang, Mark Windheim, S. Roe, M. Peggie +3 more
2005Molecules and Cells429 citations Open access
Semantic Scholar
Exploitation of KESTREL to identify NDRG family members as physiological substrates for SGK1 and GSK3.
J. Murray, D. Campbell, N. Morrice, Gillian C. Auld +10 more
2004Biochemical Journal364 citations Open access
Semantic Scholar
Novel cross-talk within the IKK family controls innate immunity.
K. Clark, M. Peggie, Lorna Plater, R. Sorcek +5 more
2011Biochemical Journal322 citations Open access
Semantic Scholar
Use of the Pharmacological Inhibitor BX795 to Study the Regulation and Physiological Roles of TBK1 and IκB Kinase ϵ
K. Clark, Lorna Plater, M. Peggie, P. Cohen
2009Journal of Biological Chemistry320 citations Open access
Semantic Scholar
Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase
Roger W. Hunter, Curtis C. Hughey, L. Lantier, E. Sundelin +6 more
2018Nature Medicine278 citations Open access
Semantic Scholar
Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation
Agne Kazlauskaite, R. J. Martínez-Torres, S. Wilkie, Atul Kumar +13 more
2015EMBO Reports255 citations Open access
Semantic Scholar
Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion
G. Rena, Yvonne L. Woods, Alan R. Prescott, M. Peggie +3 more
2002EMBO Journal252 citations Open access
Semantic Scholar
p38γ regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP
G. Sabio, J. S. Arthur, Yvonne Kuma, M. Peggie +6 more
2005EMBO Journal250 citations Open access
Semantic Scholar
Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages
K. Clark, Kirsty F. Mackenzie, K. Petkevicius, Y. Kristariyanto +9 more
2012Proceedings of the National Academy of Sciences of the United States of America248 citations Open access
Semantic Scholar
Control of AMPK-related kinases by USP9X and atypical Lys(29)/Lys(33)-linked polyubiquitin chains.
Abdallah K. Al-Hakim, A. Zagórska, L. Chapman, M. Deák +2 more
2008Biochemical Journal246 citations Open access
Semantic Scholar
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP‐K2 and its interaction with cytokine mRNAs
S. Rousseau, N. Morrice, M. Peggie, D. Campbell +2 more
2002EMBO Journal225 citations Open access
Semantic Scholar
Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide.
Mark Windheim, Christopher Lang, M. Peggie, Lorna Plater +1 more
2007Biochemical Journal196 citations Open access
Semantic Scholar
The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1
A. Ordureau, Hilary Smith, Mark Windheim, M. Peggie +3 more
2008Biochemical Journal185 citations Open access
Semantic Scholar
Enhanced binding of TBK1 by an optineurin mutant that causes a familial form of primary open angle glaucoma
Simon Morton, L. Hesson, M. Peggie, P. Cohen
2008FEBS Letters185 citations Open access
Semantic Scholar
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1
Yu-Chiang Lai, Chandana Kondapalli, Ronny Lehneck, J. Procter +11 more
2015EMBO Journal183 citations Open access
Semantic Scholar
Phosphorylation and 14-3-3 binding of Arabidopsis trehalose-phosphate synthase 5 in response to 2-deoxyglucose.
J. Harthill, S. Meek, N. Morrice, M. Peggie +3 more
2006The Plant Journal179 citations
Semantic Scholar
The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
Kashyap A. Patel, M. Foretz, A. Marion, D. Campbell +14 more
2014Nature Communications163 citations Open access
Semantic Scholar
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
Agne Kazlauskaite, V. Kelly, Clare Johnson, Carla Baillie +7 more
2014Open Biology146 citations Open access
Semantic Scholar
Evidence that glycogen synthase kinase‐3 isoforms have distinct substrate preference in the brain
Marc P. M. Soutar, Woo-Yang Kim, R. Williamson, M. Peggie +5 more
2010Journal of Neurochemistry135 citations
Semantic Scholar
MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling.
J. Darragh, A. Soloaga, Victoria A. Beardmore, A. Wingate +3 more
2005Biochemical Journal130 citations Open access
Semantic Scholar
Interleukin-1 (IL-1) Induces the Lys63-Linked Polyubiquitination of IL-1 Receptor-Associated Kinase 1 To Facilitate NEMO Binding and the Activation of IκBα Kinase
Mark Windheim, M. J. Stafford, M. Peggie, P. Cohen
2008Molecular and Cellular Biology128 citations Open access
Semantic Scholar
Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology.
Mark Windheim, M. Peggie, P. Cohen
2008Biochemical Journal122 citations Open access
Semantic Scholar
Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling
S. Strickson, Christoph H. Emmerich, Eddy T. H. Goh, Jiazhen Zhang +8 more
2017Proceedings of the National Academy of Sciences of the United States of America115 citations Open access
Semantic Scholar
An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation
Jiazhen Zhang, K. Clark, T. Lawrence, M. Peggie +1 more
2014Biochemical Journal110 citations Open access
Semantic Scholar
GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis.
Darya Zibrova, F. Vandermoere, Olga Göransson, M. Peggie +8 more
2017Biochemical Journal106 citations Open access
Semantic Scholar
Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells
M. López-Peláez, D. Lamont, M. Peggie, N. Shpiro +2 more
2014Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
Ppm1E is an in cellulo AMP-activated protein kinase phosphatase.
M. Voss, James Paterson, Ian R. Kelsall, Cristina Martín‐Granados +3 more
2011Cellular Signalling103 citations
Semantic Scholar
14‐3‐3s regulate fructose‐2,6‐bisphosphate levels by binding to PKB‐phosphorylated cardiac fructose‐2,6‐bisphosphate kinase/phosphatase
Mercedes Pozuelo Rubio, M. Peggie, B. Wong, N. Morrice +1 more
2003EMBO Journal101 citations Open access
Semantic Scholar
Nur77 is phosphorylated in cells by RSK in response to mitogenic stimulation.
A. Wingate, David G. Campbell, M. Peggie, J. S. Arthur
2006Biochemical Journal98 citations Open access
Semantic Scholar
An analysis of the phosphorylation and activation of extracellular-signal-regulated protein kinase 5 (ERK5) by mitogen-activated protein kinase kinase 5 (MKK5) in vitro.
N. Mody, D. Campbell, N. Morrice, M. Peggie +1 more
2003Biochemical Journal97 citations Open access
Semantic Scholar
Structure of PINK1 and mechanisms of Parkinson's disease-associated mutations
Atul Kumar, J. Tamjar, Andrew D. Waddell, Helen I. Woodroof +5 more
2017eLife96 citations Open access
Semantic Scholar
Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
Alexander von Wilamowitz-Moellendorff, Roger W. Hunter, M. Garcı́a-Rocha, L. Kang +11 more
2013Diabetes94 citations Open access
Semantic Scholar
The tRNA methylase METTL1 is phosphorylated and inactivated by PKB and RSK in vitro and in cells
Robert A. Cartlidge, A. Knebel, M. Peggie, A. Alexandrov +2 more
2005EMBO Journal92 citations Open access
Semantic Scholar
TAK1-binding protein 1 is a pseudophosphatase.
Sarah H Conner, Gursant S. Kular, M. Peggie, S. Shepherd +3 more
2006Biochemical Journal84 citations Open access
Semantic Scholar
Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM
D. Varshney, Alain-Pierre Petit, Juan A. Bueren-Calabuig, Chimed Jansen +6 more
2016Nucleic Acids Research76 citations Open access
Semantic Scholar
The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser358 in adipocytes
Emma Henriksson, H. Jones, Kashyap A. Patel, M. Peggie +3 more
2012Biochemical Journal73 citations Open access
Semantic Scholar
Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1
Ning Zhang, S. Gordon, M. J. Fritsch, Noor Esoof +8 more
2015Journal of Neuroscience71 citations Open access
Semantic Scholar
Inaugural Article: Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4
Hilary Smith, M. Peggie, D. Campbell, F. Vandermoere +2 more
200971 citations
Semantic Scholar
Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs
Graeme K. Carnegie, Judith E. Sleeman, N. Morrice, C. Hastie +4 more
2003Journal of Cell Science66 citations Open access
Semantic Scholar
Characterization of the reversible phosphorylation and activation of ERK8.
Iva Klevernic, M. J. Stafford, N. Morrice, M. Peggie +2 more
2006Biochemical Journal64 citations
Semantic Scholar
Essential functions of Sds22p in chromosome stability and nuclear localization of PP1.
M. Peggie, Sarah H. Mackelvie, A. Bloecher, Elena V. Knatko +2 more
2002Journal of Cell Science64 citations
Semantic Scholar
Relative Resistance of Cdk5-phosphorylated CRMP2 to Dephosphorylation*
A. Cole, Marc P. M. Soutar, Makoto Rembutsu, Lidy van Aalten +6 more
2008Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL.
J. Murray, D. Campbell, M. Peggie, A. Mora +1 more
2004Biochemical Journal50 citations Open access
Semantic Scholar
Interleukin‐1 stimulated activation of the COT catalytic subunit through the phosphorylation of Thr290 and Ser62
M. J. Stafford, N. Morrice, M. Peggie, P. Cohen
2006FEBS Letters46 citations Open access
Semantic Scholar
DHX15 regulates CMTR1-dependent gene expression and cell proliferation
F. Inesta-Vaquera, V. Chaugule, Alison Galloway, L. Chandler +4 more
2017Life Science Alliance43 citations Open access
Semantic Scholar
Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells*
Eduardo Pauls, N. Shpiro, M. Peggie, E. Young +4 more
2012Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3
Jiazhen Zhang, Thomas J. Macartney, M. Peggie, P. Cohen
2017Biochemical Journal40 citations Open access
Semantic Scholar
Nogo-B is a new physiological substrate for MAPKAP-K2.
S. Rousseau, M. Peggie, D. Campbell, A. Nebreda +1 more
2005Biochemical Journal34 citations Open access
Semantic Scholar
DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA
A. Ordureau, Karine Enesa, S. Nanda, Brice LeFrançois +4 more
2013Journal of Biological Chemistry30 citations Open access
Semantic Scholar

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