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Marc P. M. Soutar · SciRah

Researcher profile · Semantic Scholar

Marc P. M. Soutar

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Marc P. M. Soutar — researcher profile on SciRah

h-index: 15
Works: 31
Citations: 1,199

Most-cited papers

Inhibition of LRRK2 kinase activity stimulates macroautophagy
C. Manzoni, A. Mamais, S. Dihanich, R. Abeti +6 more
2013Biochimica et Biophysica Acta148 citations Open access
Semantic Scholar
A missense mutation in KCTD17 causes autosomal dominant myoclonus-dystonia.
N. Mencacci, I. Rubio‐Agusti, A. Zdebik, F. Asmus +29 more
2015American Journal of Human Genetics138 citations Open access
Semantic Scholar
Evidence that glycogen synthase kinase‐3 isoforms have distinct substrate preference in the brain
Marc P. M. Soutar, Woo-Yang Kim, R. Williamson, M. Peggie +5 more
2010Journal of Neurochemistry135 citations
Semantic Scholar
Intracellular pH Modulates Autophagy and Mitophagy*
A. Berezhnov, Marc P. M. Soutar, E. I. Fedotova, M. S. Frolova +3 more
2016Journal of Biological Chemistry110 citations Open access
Semantic Scholar
mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1
C. Manzoni, A. Mamais, Dorien A. Roosen, S. Dihanich +7 more
2016Scientific Reports84 citations Open access
Semantic Scholar
Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification
L. Schottlaender, R. Abeti, Z. Jaunmuktane, C. Macmillan +83 more
2020American Journal of Human Genetics79 citations Open access
Semantic Scholar
FBS/BSA media concentration determines CCCP’s ability to depolarize mitochondria and activate PINK1-PRKN mitophagy
Marc P. M. Soutar, Liam Kempthorne, Emily Annuario, C. Luft +4 more
2019Autophagy73 citations Open access
Semantic Scholar
Mouse hypothalamic GT1-7 cells demonstrate AMPK-dependent intrinsic glucose-sensing behaviour
C. Beall, D. Hamilton, Jennifer E. G. Gallagher, L. Logie +9 more
2012Diabetologia66 citations Open access
Semantic Scholar
AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons
Marc P. M. Soutar, Liam Kempthorne, Shuichi Miyakawa, Emily Annuario +9 more
2018Scientific Reports63 citations Open access
Semantic Scholar
Increased CRMP2 phosphorylation is observed in Alzheimer's disease; does this tell us anything about disease development?
Marc P. M. Soutar, Paul Thornhill, A. Cole, C. Sutherland
2009Current Alzheimer Research58 citations
Semantic Scholar
Relative Resistance of Cdk5-phosphorylated CRMP2 to Dephosphorylation*
A. Cole, Marc P. M. Soutar, Makoto Rembutsu, Lidy van Aalten +6 more
2008Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
Marc P. M. Soutar, Daniela Melandri, B. O'Callaghan, Emily Annuario +25 more
2022Brain : a journal of neurology49 citations Open access
Semantic Scholar
Deficiency of Parkinson's disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation
Marta Delgado-Camprubi, Noemí Esteras, Marc P. M. Soutar, H. Plun-Favreau +1 more
2016Cell Death and Differentiation43 citations Open access
Semantic Scholar
Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation
Marta Delgado-Camprubi, Noemí Esteras, Marc P. M. Soutar, H. Plun-Favreau +1 more
2017Cell Death and Differentiation37 citations Open access
Semantic Scholar
mTOR independent alteration in ULK1 Ser758 phosphorylation following chronic LRRK2 kinase inhibition
C. Manzoni, A. Mamais, S. Dihanich, Marc P. M. Soutar +8 more
2018Bioscience Reports18 citations Open access
Semantic Scholar
Novel procedure to investigate the effect of phosphorylation on protein complex formation in vitro and in cells.
Makoto Rembutsu, Marc P. M. Soutar, Lidy Van Aalten, Robert Gourlay +5 more
2008Biochemistry15 citations
Semantic Scholar
Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at Chr16q11.2 and on the MAPT H1 allele
Marc P. M. Soutar, Daniela Melandri, Emily Annuario, Amy E. Monaghan +22 more
2020bioRxiv11 citations Open access
Semantic Scholar
Oleate induces KATP channel-dependent hyperpolarization in mouse hypothalamic glucose-excited neurons without altering cellular energy charge
S. Dadak, C. Beall, Julia M. Vlachaki Walker, Marc P. M. Soutar +2 more
2017Neuroscience11 citations Open access
Semantic Scholar
KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy
Capucine de Talhouët, Noemi Esteras, Marc P. M. Soutar, B. O'Callaghan +1 more
2024bioRxiv8 citations Open access
Semantic Scholar
Haploinsufficiency of progranulin causes cell type specific impairments in PINK1/Parkin mitophagy
Jackie M. Casey, Daniela Melandri, C. Arber, Marc P. M. Soutar +7 more
2023Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Advances in Alzheimer’s Research
D. Lahiri, A. Cole, A. Ghori, Ajay Gupta +43 more
20131 citations Open access
Semantic Scholar
The AMP-Activated Protein Kinase (AMPK)-Uncoupling Protein 2 (UCP2) pathways controls glucose sensing and whole body glucose counterregulation in mouse
C. Beall, D. Hamilton, L. Logie, Fiona B. Ashford +7 more
20121 citations
Semantic Scholar
Glucose concentration of neuronal media formulations influences PINK1-dependent mitophagy in human iNeurons
B. O'Callaghan, Daniela Melandri, Darija Soltic, Katharina Cosker +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
A CRISPR-CAS9 high throughput machine-learning platform for modulation of genes involved in Parkinson’s disease-associated PINK1-mitophagy in iPSC-derived dopaminergic neurons
Marc P. M. Soutar, Benedetta Carbone, Petya Kindalova, Rahil Mehrizi +10 more
2025bioRxiv0 citations
Semantic Scholar
Haploinsufficiency of progranulin causes impairments in PINK/PARKIN mitophagy
Jackie M. Casey, Daniela Melandri, C. Arber, Marc P. M. Soutar +6 more
2020Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Oleate induces KATP channel-dependent hyperpolarisation in mouse hypothalamic glucose-excited neurones without altering cellular energy charge
S. Dadak, C. Beall, Julia M. Vlachaki Walker, Marc P. M. Soutar +3 more
20170 citations
Semantic Scholar
Oleate induces KATP channel-dependent hyperpolarisation in mouse hypothalamic glucose-excited neurones without altering cellular energy charge
C. Beall, Julia M. Vlachaki Walker, Marc P. M. Soutar, M. L. Ashford
20170 citations
Semantic Scholar
KATP channel-dependent hyperpolarisation in mouse hypothalamic glucose-excited neurones without altering cellular energy charge
C. Beall, Julia M. Vlachaki Walker, Marc P. M. Soutar, M. Ashford
20170 citations
Semantic Scholar
A missense mutation in the KCTD17 gene causes autosomal dominant myoclonus-dystonia
N. Mencacci, I. Rubio-Augusti, A. Zdebik, F. Asmus +25 more
20150 citations
Semantic Scholar
Cdk 5-phosphorylated CRMP 2 to Relative Resistance of Mechanisms of Signal Transduction :
Ping Kun, C. Sutherland, H. Mclauchlan, M. Peggie +7 more
20080 citations
Semantic Scholar
Performance evaluation of an automated microparticle enzyme immunoassay (MEIA) for holo-transcobalamin, AxSYM (R) HoloTC
Edward Valente, J. Brady, L. McGregor, Marc P. M. Soutar +2 more
20060 citations
Semantic Scholar

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