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A. Ordureau · SciRah

Researcher profile · Semantic Scholar

A. Ordureau

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A. Ordureau — researcher profile on SciRah

h-index: 39
Works: 81
Citations: 9,647

Most-cited papers

The BioPlex Network: A Systematic Exploration of the Human Interactome
Edward L. Huttlin, Lily Ting, R. Bruckner, F. Gebreab +25 more
2015Cell1,371 citations Open access
Semantic Scholar
Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
E. Cirulli, Brittany N. Lasseigne, S. Petrovski, P. Sapp +67 more
2015Science963 citations Open access
Semantic Scholar
The PINK1-PARKIN mitochondrial ubiquitylation pathway drives a program of TBK1 activation and recruitment of OPTN and NDP52 to promote mitophagy
Jin-Mi Heo, A. Ordureau, João A. Paulo, Jesse Rinehart +1 more
2015Molecules and Cells826 citations Open access
Semantic Scholar
Quantitative proteomics reveal a feed-forward model for mitochondrial PARKIN translocation and UB chain synthesis
A. Ordureau, Shireen A. Sarraf, David M. Duda, Jin-Mi Heo +10 more
2014Molecules and Cells668 citations Open access
Semantic Scholar
Building and decoding ubiquitin chains for mitophagy
J. Harper, A. Ordureau, Jin-Mi Heo
2018Nature reviews. Molecular cell biology626 citations
Semantic Scholar
Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Christoph H. Emmerich, A. Ordureau, S. Strickson, J. S. Arthur +3 more
2013Proceedings of the National Academy of Sciences of the United States of America429 citations Open access
Semantic Scholar
14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
R. Nichols, Nicolas Dzamko, N. Morrice, David G. Campbell +7 more
2010Biochemical Journal401 citations Open access
Semantic Scholar
Endogenous Parkin Preserves Dopaminergic Substantia Nigral Neurons following Mitochondrial DNA Mutagenic Stress
Alicia M. Pickrell, Chiu-Hui Huang, Scott R. Kennedy, A. Ordureau +4 more
2015Neuron312 citations Open access
Semantic Scholar
TEX264 is an ER-resident ATG8-interacting protein critical for endoplasmic reticulum remodeling during nutrient stress
Heeseon An, A. Ordureau, João A. Paulo, C. J. Shoemaker +2 more
2019Molecules and Cells257 citations Open access
Semantic Scholar
RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway
Jin-Mi Heo, A. Ordureau, Sharan Swarup, João A. Paulo +3 more
2018Science Advances195 citations Open access
Semantic Scholar
Global landscape and dynamics of Parkin and USP30-dependent ubiquitylomes in iNeurons during mitophagic signaling
A. Ordureau, João A. Paulo, Jiu-Chun Zhang, Heeseon An +5 more
2020Molecules and Cells192 citations Open access
Semantic Scholar
TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling
Bin Wang, Zu-Liang Jie, Donghyun Joo, A. Ordureau +12 more
2017Nature186 citations Open access
Semantic Scholar
The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys63-linked polyubiquitination of IRAK1
A. Ordureau, Hilary Smith, Mark Windheim, M. Peggie +3 more
2008Biochemical Journal185 citations Open access
Semantic Scholar
Dynamics of PARKIN-dependent mitochondrial ubiquitylation in induced-neurons and model systems revealed by digital snapshot proteomics
A. Ordureau, João A. Paulo, Wei Zhang, Tim Ahfeldt +8 more
2018Molecules and Cells178 citations Open access
Semantic Scholar
Polyubiquitin Binding to Optineurin Is Required for Optimal Activation of TANK-binding Kinase 1 and Production of Interferon β*
C. Gleason, A. Ordureau, Robert Gourlay, J. C. Arthur +1 more
2011Journal of Biological Chemistry177 citations Open access
Semantic Scholar
Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes
Christopher M. Rose, M. Isasa, A. Ordureau, Miguel A. Prado +5 more
2016Cell Systems170 citations Open access
Semantic Scholar
Polyubiquitin binding to ABIN1 is required to prevent autoimmunity
S. Nanda, Ram K. C. Venigalla, A. Ordureau, J. Patterson-Kane +4 more
2011Journal of Experimental Medicine165 citations Open access
Semantic Scholar
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes
Wei Zhang, Kuen-Phon Wu, M. A. Sartori, H. Kamadurai +22 more
2016Molecules and Cells160 citations Open access
Semantic Scholar
Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C
N. Brown, R. Vanderlinden, E. R. Watson, Florian Weissmann +25 more
2016Cell148 citations Open access
Semantic Scholar
Cyclin C is a haploinsufficient tumor suppressor
Na Li, A. Fassl, J. Chick, H. Inuzuka +34 more
2014Nature Cell Biology148 citations Open access
Semantic Scholar
EDF1 coordinates cellular responses to ribosome collisions
Niladri Sinha, A. Ordureau, K. Best, J. A. Saba +11 more
2020eLife147 citations Open access
Semantic Scholar
Quantifying Ubiquitin Signaling
A. Ordureau, C. Münch, J. Harper
2015Molecules and Cells138 citations Open access
Semantic Scholar
TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL.
Ayaz Najafov, A. Mookhtiar, Hoang Son Luu, A. Ordureau +5 more
2019Molecules and Cells125 citations Open access
Semantic Scholar
The endoplasmic reticulum P5A-ATPase is a transmembrane helix dislocase
Michael J. McKenna, S. Sim, A. Ordureau, Lianjie Wei +3 more
2020Science123 citations Open access
Semantic Scholar
Systematic Quantitative Analysis of Ribosome Inventory Upon Nutrient Stress
Heeseon An, A. Ordureau, Maria Schultz, João A. Paulo +1 more
2020Nature117 citations Open access
Semantic Scholar
The ribotoxic stress response drives UV-mediated cell death
Niladri Sinha, Connor McKenney, Zhong Y. Yeow, Jeffrey J Li +8 more
2024Cell107 citations Open access
Semantic Scholar
G1 cyclins link proliferation, pluripotency and differentiation of embryonic stem cells
Li-Jun Liu, W. Michowski, H. Inuzuka, K. Shimizu +14 more
2017Nature Cell Biology107 citations Open access
Semantic Scholar
Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons
J. Goldsmith, A. Ordureau, J. Harper, E. Holzbaur
2022Neuron102 citations Open access
Semantic Scholar
Temporal Proteomics During Neurogenesis Reveals Large-scale Proteome and Organelle Remodeling via Selective Autophagy
A. Ordureau, Felix Kraus, Jiu-Chun Zhang, Heeseon An +4 more
2021Molecules and Cells99 citations Open access
Semantic Scholar
Micronuclear collapse from oxidative damage
Melody DiBona, Yanyang Chen, Albert S. Agustinus, Alice Mazzagatti +28 more
2024Science73 citations Open access
Semantic Scholar
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1
O. Antico, A. Ordureau, Michael Stevens, F. Singh +9 more
2021Science Advances64 citations Open access
Semantic Scholar
Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model
Gustavo Morrone Parfitt, E. Coccia, Camille Goldman, Kristen Whitney +9 more
2024Nature Communications57 citations Open access
Semantic Scholar
UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER
P. A. DaRosa, Ivan Penchev, Samantha C. Gumbin, Francesco Scavone +9 more
2024Nature55 citations Open access
Semantic Scholar
Pathogenic Pathways in Early-Onset Autosomal Recessive Parkinson's Disease Discovered Using Isogenic Human Dopaminergic Neurons
Tim Ahfeldt, A. Ordureau, Christina Bell, Lily Sarrafha +10 more
2019Stem Cell Reports53 citations Open access
Semantic Scholar
mTORC1-CTLH E3 Ligase Regulates the Degradation of HMG-CoA Synthase 1 through the Pro/N-Degron Pathway
S. Yi, Sara Šepić, Brenda A. Schulman, A. Ordureau +1 more
2024Molecules and Cells46 citations Open access
Semantic Scholar
Vaccinia E5 is a major inhibitor of the DNA sensor cGAS
N. Yang, Yi Wang, P. Dai, Tuo Li +11 more
2021bioRxiv44 citations Open access
Semantic Scholar
The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells
M. Jacoupy, E. Hamon-Keromen, A. Ordureau, Z. Erpapazoglou +11 more
2019Scientific Reports44 citations Open access
Semantic Scholar
Pharmacological PINK1 activation ameliorates Pathology in Parkinson’s Disease models
R. Chin, Rishi Rakhit, D. Ditsworth, Chengzhong Wang +20 more
2023bioRxiv43 citations Open access
Semantic Scholar
Ubiquitin chain-elongating enzyme UBE2S activates the RING E3 ligase APC/C for substrate priming
Raquel C. Martinez-Chacin, Tatyana Bodrug, Derek L. Bolhuis, K. Kedziora +11 more
2020Nature Structural & Molecular Biology40 citations Open access
Semantic Scholar
Pellino1 Is Required for Interferon Production by Viral Double-stranded RNA*
Karine Enesa, A. Ordureau, Hilary Smith, D. Barford +4 more
2012Journal of Biological Chemistry33 citations Open access
Semantic Scholar
RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.
Ayaz Najafov, Hoang Son Luu, A. Mookhtiar, Lauren Mifflin +5 more
2020Molecules and Cells31 citations Open access
Semantic Scholar
DEAF1 Is a Pellino1-interacting Protein Required for Interferon Production by Sendai Virus and Double-stranded RNA
A. Ordureau, Karine Enesa, S. Nanda, Brice LeFrançois +4 more
2013Journal of Biological Chemistry30 citations Open access
Semantic Scholar
mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase
Brittany Q. Pham, S. Yi, A. Ordureau, Heeseon An
2025Cell Reports26 citations Open access
Semantic Scholar
Substitution of PINK1 Gly411 modulates substrate receptivity and turnover
Fabienne C. Fiesel, Dominika Fričová, Caleb S Hayes, Matt Coban +21 more
2022Autophagy24 citations Open access
Semantic Scholar
Quantitative Phospho-proteomic Analysis of TNFα/NFκB Signaling Reveals a Role for RIPK1 Phosphorylation in Suppressing Necrotic Cell Death*
Firaz Mohideen, João A. Paulo, A. Ordureau, S. Gygi +1 more
2017Molecular & Cellular Proteomics23 citations Open access
Semantic Scholar
TOM20-Driven E3 Ligase Recruitment Regulates Mitochondrial Dynamics Through PLD6
Anat Raiff, Shidong Zhao, Aizat Bekturova, Colin Zenge +8 more
2025Nature Chemical Biology21 citations
Semantic Scholar
Ubiquitin System Mutations in Neurological Diseases
Colin Zenge, A. Ordureau
2024TIBS -Trends in Biochemical Sciences. Regular ed17 citations Open access
Semantic Scholar
Acute unfolding of a single protein immediately stimulates recruitment of ubiquitin protein ligase E3C (UBE3C) to 26S proteasomes
Colin D. Gottlieb, Airlia C. S. Thompson, A. Ordureau, J. Harper +1 more
2019Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Machine perception liquid biopsy identifies brain tumours via systemic immune and tumour microenvironment signature
Dana Goerzen, Mijin Kim, C. Schroff, Margaret Ngoc Hoang +10 more
2025Nature Nanotechnology15 citations Open access
Semantic Scholar
Functional conservation and divergence of the helix‐turn‐helix motif of E2 ubiquitin‐conjugating enzymes
Kaeli A. Welsh, Derek L. Bolhuis, Anneroos E. Nederstigt, J. Boyer +10 more
2021EMBO Journal15 citations Open access
Semantic Scholar

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