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F. Schumacher · SciRah

Researcher profile · Semantic Scholar

F. Schumacher

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F. Schumacher — researcher profile on SciRah

h-index: 30
Works: 119
Citations: 3,074

Most-cited papers

Interleukin-22 protects intestinal stem cells against genotoxic stress
Konrad Gronke, Pedro P. Hernández, J. Zimmermann, Christoph S. N. Klose +9 more
2019Nature343 citations Open access
Semantic Scholar
The glucose transporter GLUT3 controls T helper 17 cell responses through glycolytic-epigenetic reprogramming
Sophia M. Hochrein, Hao Wu, Miriam Eckstein, L. Arrigoni +12 more
2022Cell Metabolism222 citations Open access
Semantic Scholar
Antidepressants act by inducing autophagy controlled by sphingomyelin–ceramide
Anne Gulbins, F. Schumacher, K. A. Becker, B. Wilker +10 more
2018Molecular Psychiatry214 citations Open access
Semantic Scholar
Formulation and ex vivo evaluation of polymeric nanoparticles for controlled delivery of corticosteroids to the skin and the corneal epithelium
Benjamin Balzus, F. F. Sahle, S. Hönzke, C. Gerecke +4 more
2017European journal of pharmaceutics and biopharmaceutics86 citations
Semantic Scholar
Methionine restriction prevents onset of type 2 diabetes in NZO mice
T. Castaño-Martínez, F. Schumacher, Silke Schumacher, B. Kochlik +9 more
2019The FASEB Journal78 citations Open access
Semantic Scholar
Biocompatibility and characterization of polyglycerol-based thermoresponsive nanogels designed as novel drug-delivery systems and their intracellular localization in keratinocytes
C. Gerecke, Alexander Edlich, M. Giulbudagian, F. Schumacher +11 more
2017Nanotoxicology70 citations Open access
Semantic Scholar
Monitoring the Sphingolipid de novo Synthesis by Stable-Isotope Labeling and Liquid Chromatography-Mass Spectrometry
Dominik Wigger, E. Gulbins, B. Kleuser, F. Schumacher
2019Front. Cell Dev. Biol.56 citations Open access
Semantic Scholar
Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice.
Bodo Speckmann, Sarah Schulz, Franziska Hiller, D. Hesse +6 more
2017Journal of Nutritional Biochemistry55 citations Open access
Semantic Scholar
Identification of functional lipid metabolism biomarkers of brown adipose tissue aging
S. Gohlke, V. Zagoriy, Alvaro Cuadros Inostroza, M. Méret +13 more
2019Molecular Metabolism54 citations Open access
Semantic Scholar
Inflammation in Children with CKD Linked to Gut Dysbiosis and Metabolite Imbalance
J. Holle, H. Bartolomaeus, U. Loeber, F. Behrens +24 more
2022medRxiv51 citations Open access
Semantic Scholar
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
Judith Lang, Patrick S. Bohn, H. Bhat, H. Jastrow +27 more
2020Nature Communications51 citations Open access
Semantic Scholar
Ceramide levels in blood plasma correlate with major depressive disorder severity and its neutralization abrogates depressive behavior in mice
F. Schumacher, M. Edwards, C. Mühle, A. Carpinteiro +12 more
2022Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Vitamin C promotes decitabine or azacytidine induced DNA hydroxymethylation and subsequent reactivation of the epigenetically silenced tumour suppressor CDKN1A in colon cancer cells
C. Gerecke, F. Schumacher, Alexander Edlich, A. Wetzel +5 more
2018OncoTarget44 citations Open access
Semantic Scholar
Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake
Christian Hausmann, C. Zoschke, Christopher Wolff, M. Darvin +11 more
2019Scientific Reports43 citations Open access
Semantic Scholar
Immunity-related GTPase induces lipophagy to prevent excess hepatic lipid accumulation
K. Schwerbel, A. Kamitz, Natalie Krahmer, N. Hallahan +18 more
2020Journal of Hepatology42 citations Open access
Semantic Scholar
Sphingosine 1-phosphate metabolism and insulin signaling.
Dominik Wigger, F. Schumacher, S. Schneider-Schaulies, B. Kleuser
2021Cellular Signalling34 citations
Semantic Scholar
Liposomal FRET Assay Identifies Potent Drug‐Like Inhibitors of the Ceramide Transport Protein (CERT)
D. Samaha, H. H. Hamdo, Xiaojing Cong, F. Schumacher +7 more
2020Chemistry34 citations Open access
Semantic Scholar
Sphingosine-coating of plastic surfaces prevents ventilator-associated pneumonia
A. Seitz, F. Schumacher, Jennifer E. Baker, Matthias Soddemann +9 more
2019Journal of molecular medicine32 citations Open access
Semantic Scholar
Vitamin C in combination with inhibition of mutant IDH1 synergistically activates TET enzymes and epigenetically modulates gene silencing in colon cancer cells
C. Gerecke, F. Schumacher, Alide Berndzen, T. Homann +1 more
2019Epigenetics32 citations Open access
Semantic Scholar
Synthesis of poly(lactide-co-glycerol) as a biodegradable and biocompatible polymer with high loading capacity for dermal drug delivery.
F. Zabihi, P. Graff, F. Schumacher, B. Kleuser +2 more
2018Nanoscale31 citations
Semantic Scholar
Cell-intrinsic ceramides determine T cell function during melanoma progression
Matthias Hose, Anne Günther, Eyad Naser, F. Schumacher +10 more
2022bioRxiv30 citations Open access
Semantic Scholar
S1P and Plasmalogen Derived Fatty Aldehydes in Cellular Signaling and Functions
D. Ebenezer, P. Fu, R. Ramchandran, Alison W. Ha +6 more
2020Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids30 citations Open access
Semantic Scholar
Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma
F. Schumacher, A. Carpinteiro, M. Edwards, Gregory Wilson +8 more
2022Journal of molecular medicine29 citations Open access
Semantic Scholar
Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels
F. Rancan, H. Volkmann, M. Giulbudagian, F. Schumacher +5 more
2019Pharmaceutics27 citations Open access
Semantic Scholar
Ventilator-induced lung injury is aggravated by antibiotic mediated microbiota depletion in mice
S. Wienhold, M. Macrì, G. Nouailles, K. Dietert +10 more
2018Critical Care26 citations Open access
Semantic Scholar
Acid sphingomyelinase deactivation post-ischemia promotes brain angiogenesis and remodeling by small extracellular vesicles
Ayan Mohamud Yusuf, N. Hagemann, Xiaoni Zhang, M. Zafar +17 more
2022Basic Research in Cardiology25 citations Open access
Semantic Scholar
Arsenic-containing hydrocarbons: effects on gene expression, epigenetics, and biotransformation in HepG2 cells
S. M. Müller, H. Finke, F. Ebert, J. F. Kopp +5 more
2018Archives of Toxicology25 citations
Semantic Scholar
Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA3 Receptor Subtype and is Increased in Obesity
Susann Fayyaz, L. Japtok, F. Schumacher, Dominik Wigger +5 more
2017Cellular Physiology and Biochemistry25 citations Open access
Semantic Scholar
Antiviral and Anti-Inflammatory Activities of Fluoxetine in a SARS-CoV-2 Infection Mouse Model
D. Péricat, S. Leon-Icaza, Marina Sanchez Rico, C. Mühle +18 more
2022International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Sphingolipids: Effectors and Achilles Heals in Viral Infections?
S. Schneider-Schaulies, F. Schumacher, Dominik Wigger, Marie Schöl +4 more
2021Cells24 citations Open access
Semantic Scholar
Use of Acid Ceramidase and Sphingosine Kinase Inhibitors as Antiviral Compounds Against Measles Virus Infection of Lymphocytes in vitro
Anika Grafen, F. Schumacher, Janice Chithelen, B. Kleuser +2 more
2019Front. Cell Dev. Biol.24 citations Open access
Semantic Scholar
Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects.
H. Carstens, F. Schumacher, S. Keitsch, Melanie Kramer +16 more
2019Cellular Physiology and Biochemistry22 citations Open access
Semantic Scholar
Pathological manifestations of Farber disease in a new mouse model
Nadine Beckmann, Stephanie Kadow, F. Schumacher, J. Göthert +11 more
2018Biological chemistry22 citations Open access
Semantic Scholar
The Forebrain-Specific Overexpression of Acid Sphingomyelinase Induces Depressive-Like Symptoms in Mice
I. Zoicas, F. Schumacher, B. Kleuser, M. Reichel +4 more
2020Cells21 citations Open access
Semantic Scholar
Epigenetic DNA Methylation of EBI3 Modulates Human Interleukin-35 Formation via NFkB Signaling: A Promising Therapeutic Option in Ulcerative Colitis
A. Wetzel, B. Scholtka, F. Schumacher, H. Rawel +2 more
2021International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Neutral Sphingomyelinase is an Affective Valence-Dependent Regulator of Learning and Memory.
L. Kalinichenko, Laila Abdel-Hafiz, An-Li Wang, C. Mühle +15 more
2020Cerebral Cortex19 citations
Semantic Scholar
A Role of Sphingosine in the Intracellular Survival of Neisseria gonorrhoeae
F. Solger, Tobias C. Kunz, Julian Fink, K. Paprotka +6 more
2020Frontiers in Cellular and Infection Microbiology18 citations Open access
Semantic Scholar
Core‐multishell nanocarriers enhance drug penetration and reach keratinocytes and antigen‐presenting cells in intact human skin
J. Frombach, M. Unbehauen, I. Kurniasih, F. Schumacher +8 more
2019Journal of Controlled Release18 citations
Semantic Scholar
Inhibition of acid sphingomyelinase increases regulatory T cells in humans
Teresa Wiese, F. Dennstädt, C. Hollmann, S. Stonawski +15 more
2021Brain Communications17 citations Open access
Semantic Scholar
Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2
B. Gutbier, Stefanie M. Schönrock, Carolin Ehrler, R. Haberberger +22 more
2018Critical Care Medicine17 citations Open access
Semantic Scholar
Down‐regulation of acid sphingomyelinase and neutral sphingomyelinase‐2 inversely determines the cellular resistance to plasmalemmal injury by pore‐forming toxins
R. Schoenauer, Yu Larpin, E. Babiychuk, Patrick Drücker +7 more
2018The FASEB Journal17 citations Open access
Semantic Scholar
The sphingosine 1-phosphate breakdown product, (2E)-hexadecenal, forms protein adducts and glutathione conjugates in vitro[S]
F. Schumacher, C. Neuber, H. Finke, Kai Nieschalke +3 more
2017Journal of Lipid Research17 citations Open access
Semantic Scholar
CFTR modulator therapy alters plasma sphingolipid profiles in people with cystic fibrosis.
D. Westhölter, F. Schumacher, Nuria Wülfinghoff, S. Sutharsan +7 more
2022Journal of Cystic Fibrosis16 citations Open access
Semantic Scholar
Click-correlative light and electron microscopy (click-AT-CLEM) for imaging and tracking azido-functionalized sphingolipids in bacteria
Simon Peters, L. Kaiser, Julian Fink, F. Schumacher +7 more
2021Scientific Reports16 citations Open access
Semantic Scholar
Acid sphingomyelinase – a regulator of canonical transient receptor potential channel 6 (TRPC6) activity
S. Zeitler, Lian Ye, A. Andreyeva, F. Schumacher +9 more
2019Journal of Neurochemistry16 citations Open access
Semantic Scholar
Measles Virus Infection Fosters Dendritic Cell Motility in a 3D Environment to Enhance Transmission to Target Cells in the Respiratory Epithelium
S. Derakhshani, Andrea Kurz, L. Japtok, F. Schumacher +6 more
2019Frontiers in Immunology15 citations Open access
Semantic Scholar
The role of chemoprophylactic agents in modulating platelet aggregability after traumatic brain injury
M. Morris, Farzaan Kassam, A. Bercz, Nadine Beckmann +4 more
2019Journal of Surgical Research15 citations Open access
Semantic Scholar
Acid Sphingomyelinase Impacts Canonical Transient Receptor Potential Channels 6 (TRPC6) Activity in Primary Neuronal Systems
S. Zeitler, F. Schumacher, Juliana Monti, Daniela Anni +6 more
2020Cells14 citations Open access
Semantic Scholar
Intestinal Acid Sphingomyelinase Protects From Severe Pathogen-Driven Colitis
J. Meiners, Vittoria Palmieri, R. Klopfleisch, J. Ebel +12 more
2019Frontiers in Immunology14 citations Open access
Semantic Scholar
Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis
Charlene Börtlein, F. Schumacher, B. Kleuser, Lars Dölken +1 more
2019Front. Cell Dev. Biol.14 citations Open access
Semantic Scholar

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B. Kleuser — researcher profile on SciRah
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