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S. Keitsch · SciRah

Researcher profile · Semantic Scholar

S. Keitsch

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S. Keitsch — researcher profile on SciRah

h-index: 12
Works: 31
Citations: 721

Most-cited papers

Pharmacological Inhibition of Acid Sphingomyelinase Prevents Uptake of SARS-CoV-2 by Epithelial Cells
A. Carpinteiro, M. Edwards, M. Hoffmann, G. Kochs +23 more
2020Cell Reports Medicine177 citations Open access
Semantic Scholar
Regulation of hematogenous tumor metastasis by acid sphingomyelinase
A. Carpinteiro, K. A. Becker, L. Japtok, G. Hessler +10 more
2015EMBO Molecular Medicine87 citations Open access
Semantic Scholar
Lack of Sphingosine Causes Susceptibility to Pulmonary Staphylococcus Aureus Infections in Cystic Fibrosis
Shaghayegh Tavakoli Tabazavareh, A. Seitz, P. Jernigan, Carolin Sehl +7 more
2016Cellular Physiology and Biochemistry63 citations Open access
Semantic Scholar
Staphylococcus aureus Alpha-Toxin Disrupts Endothelial-Cell Tight Junctions via Acid Sphingomyelinase and Ceramide
K. A. Becker, Björn Fahsel, H. Kemper, Joelina Mayeres +12 more
2017Infection and Immunity53 citations Open access
Semantic Scholar
Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease
Anne Gulbins, Mareike Horstmann, A. Daser, U. Flögel +12 more
2023Frontiers in Endocrinology51 citations Open access
Semantic Scholar
Ceramide levels in blood plasma correlate with major depressive disorder severity and its neutralization abrogates depressive behavior in mice
F. Schumacher, M. Edwards, C. Mühle, A. Carpinteiro +12 more
2022Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Sphingosine prevents binding of SARS–CoV-2 spike to its cellular receptor ACE2
M. Edwards, K. A. Becker, Barbara Gripp, M. Hoffmann +13 more
2020Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma
F. Schumacher, A. Carpinteiro, M. Edwards, Gregory Wilson +8 more
2022Journal of molecular medicine29 citations Open access
Semantic Scholar
Clinical Development of Sphingosine as Anti-Bacterial Drug: Inhalation of Sphingosine in Mini Pigs has no Adverse Side Effects.
H. Carstens, F. Schumacher, S. Keitsch, Melanie Kramer +16 more
2019Cellular Physiology and Biochemistry22 citations Open access
Semantic Scholar
Pulmonary infection of cystic fibrosis mice with Staphylococcus aureus requires expression of α-toxin
S. Keitsch, Joachim Riethmüller, Matthias Soddemann, Carolin Sehl +6 more
2018Biological chemistry19 citations
Semantic Scholar
Melatonin Acts as an Antidepressant by Inhibition of the Acid Sphingomyelinase/Ceramide System
Richard S. Hoehn, Marlene Monse, E. Pohl, Sina Wranik +8 more
2016Neurosignals16 citations Open access
Semantic Scholar
Acid Ceramidase Rescues Cystic Fibrosis Mice from Pulmonary Infections
K. A. Becker, Rabea Verhaegh, H. Verhasselt, S. Keitsch +7 more
2020Infection and Immunity15 citations Open access
Semantic Scholar
Simultaneous targeting of mitochondrial Kv1.3 and lysosomal acid sphingomyelinase amplifies killing of pancreatic ductal adenocarcinoma cells in vitro and in vivo
Sameer H. Patel, Magdalena Bachmann, Stephanie Kadow, G. Wilson +10 more
2023Journal of molecular medicine11 citations Open access
Semantic Scholar
Inhibition of PI-3-K and AKT Amplifies Kv1.3 Inhibitor-Induced Death of Human T Leukemia Cells.
Tim Bergermann, L. Born, F. Ferguson, Paula Latkovic +13 more
2019Cellular Physiology and Biochemistry10 citations Open access
Semantic Scholar
Antimicrobial effects of inhaled sphingosine against Pseudomonas aeruginosa in isolated ventilated and perfused pig lungs
H. Carstens, K. Kalka, Rabea Verhaegh, F. Schumacher +11 more
2022PLoS ONE9 citations Open access
Semantic Scholar
Sphingosine as a New Antifungal Agent against Candida and Aspergillus spp.
Fahimeh Hashemi Arani, Stephanie Kadow, Melanie Kramer, S. Keitsch +6 more
2022International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Phosphatidic acid is involved in regulation of autophagy in neurons in vitro and in vivo
M. Schiller, Gregory C. Wilson, S. Keitsch, Matthias Soddemann +4 more
2024Pflügers Archiv: European Journal of Physiology8 citations Open access
Semantic Scholar
Reduced Sphingosine in Cystic Fibrosis Increases Susceptibility to Mycobacterium abscessus Infections
Fabian Schnitker, Yongjie Liu, S. Keitsch, Matthias Soddemann +6 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
Molecular targets of endothelial phosphatidic acid regulating major depressive disorder
M. Edwards, G. Wilson, S. Keitsch, Matthias Soddemann +4 more
2022Journal of Neurochemistry7 citations Open access
Semantic Scholar
Sphingosine kills intracellular Pseudomonas aeruginosa and Staphylococcus aureus
H. May, Yongjie Liu, Stephanie Kadow, Michael J. Edwards +6 more
2024Pathogens and Disease6 citations Open access
Semantic Scholar
Sphingosine is involved in PAPTP-induced death of pancreas cancer cells by interfering with mitochondrial functions
Sameer H. Patel, Gregory C. Wilson, Yuqing Wu, S. Keitsch +5 more
2024Journal of molecular medicine5 citations Open access
Semantic Scholar
Potential involvement of the bone marrow in experimental Graves’ disease and thyroid eye disease
Anne Gulbins, Mareike Horstmann, S. Keitsch, Matthias Soddemann +8 more
2023Frontiers in Endocrinology5 citations Open access
Semantic Scholar
Sphingosine kills Mycobacteria and suppresses mycobacterial lung infections
Yuqing Wu, Fabian Schnitker, Yongjie Liu, S. Keitsch +10 more
2025Journal of molecular medicine4 citations Open access
Semantic Scholar
Sphingosine-mediated death of Pseudomonas aeruginosa involves degradation of cardiolipin by the maintenance of outer lipid asymmetry system
H. Grassmé, Gregory C. Wilson, Yuqing Wu, Mike Hasenberg +5 more
2025Infection and Immunity4 citations Open access
Semantic Scholar
Interferon regulatory factor 8 regulates expression of acid ceramidase and infection susceptibility in cystic fibrosis
A. Gardner, Yuqing Wu, Rabea Verhaegh, Yong-Jie Liu +9 more
2021Journal of Biological Chemistry4 citations Open access
Semantic Scholar
Inhaled sphingosine has no adverse side effects in isolated ventilated and perfused pig lungs
H. Carstens, K. Kalka, Rabea Verhaegh, F. Schumacher +11 more
2021Scientific Reports4 citations Open access
Semantic Scholar
Role of Tyrosine Nitrosylation in Stress-Induced Major Depressive Disorder: Mechanisms and Implications
Gregory C. Wilson, S. Keitsch, Matthias Soddemann, B. Wilker +2 more
2023International Journal of Molecular Sciences2 citations Open access
Semantic Scholar
Inhibition of Acid Sphingomyelinase Blocks Infection with SARS-CoV-2
A. Carpinteiro, M. Edwards, M. Hoffmann, G. Kochs +23 more
20202 citations
Semantic Scholar
Rhinovirus infection promotes suppression of sphingosine and enhanced bacterial infection in cystic fibrosis airways
Gregory C. Wilson, S. Keitsch, B. Wilker, Matthias Soddemann +2 more
2026Journal of Biological Chemistry0 citations Open access
Semantic Scholar
[Proapoptotic antibodies as new therapeutic agents for tumor treatment].
M. Schenck, C. Börgermann, F. Dorp, M. Groneberg +9 more
2007Der Urologe (Ausg. A)0 citations
Semantic Scholar
[Identification of the molecular bases of metastasis for the development of new therapy strategies of metastatic prostate carcinoma].
M. Schenck, C. Boergermann, F. Dorp, Y. Busch +8 more
2007Der Urologe (Ausg. A)0 citations
Semantic Scholar

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B. Wilker×25
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Matthias Soddemann×20
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E. Gulbins×20
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M. Edwards×15
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K. A. Becker — researcher profile on SciRah

A. Carpinteiro×11

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Carolin Sehl×9

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Carolin Sehl — researcher profile on SciRah

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H. Grassmé — researcher profile on SciRah

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Erich Gulbins×7

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M. Kamler — researcher profile on SciRah

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