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J. Göthert · SciRah

Researcher profile · Semantic Scholar

J. Göthert

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J. Göthert — researcher profile on SciRah

h-index: 27
Works: 87
Citations: 3,239

Most-cited papers

Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes
A. Hasenberg, M. Hasenberg, Linda Männ, F. Neumann +17 more
2015Nature Methods261 citations
Semantic Scholar
Semaphorin 3A suppresses VEGF-mediated angiogenesis yet acts as a vascular permeability factor.
Lisette M. Acevedo, Samuel Barillas, S. Weis, J. Göthert +1 more
2008Blood238 citations Open access
Semantic Scholar
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation
A. Sprüssel, J. Schulte, S. Weber, M. Necke +16 more
2012Leukemia200 citations
Semantic Scholar
Endothelial β -Catenin Signaling Is Required for Maintaining Adult Blood–Brain Barrier Integrity and Central Nervous System Homeostasis
Khiem A. Tran, Xianming Zhang, D. Predescu, Xiao-Jia Huang +5 more
2015189 citations
Semantic Scholar
Bleeding, thrombosis, and anticoagulation in myeloproliferative neoplasms (MPN): analysis from the German SAL-MPN-registry
A. Kaifie, M. Kirschner, D. Wolf, C. Maintz +17 more
2016Journal of Hematology & Oncology167 citations Open access
Semantic Scholar
Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK
S. Weis, S. Lim, Kimberly M. Lutu-Fuga, Leo Barnes +6 more
2008Journal of Cell Biology165 citations Open access
Semantic Scholar
The bulk of the hematopoietic stem cell population is dispensable for murine steady-state and stress hematopoiesis.
Kristina B Schoedel, Mina N. F. Morcos, T. Zerjatke, I. Roeder +6 more
2016Blood103 citations Open access
Semantic Scholar
BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells.
M. Schemionek, C. Elling, U. Steidl, N. Bäumer +13 more
2010Blood102 citations Open access
Semantic Scholar
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
C. Nussbaum, Sarah Bannenberg, P. Keul, M. Gräler +13 more
2015Nature Communications99 citations Open access
Semantic Scholar
A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy
M. Wass, S. Göllner, B. Besenbeck, R. Schlenk +20 more
2020Leukemia83 citations Open access
Semantic Scholar
Identification of a new VHL exon and complex splicing alterations in familial erythrocytosis or von Hippel-Lindau disease.
M. Lenglet, F. Robriquet, K. Schwarz, C. Camps +47 more
2018Blood79 citations Open access
Semantic Scholar
Functional characterization of the ectopically expressed olfactory receptor 2AT4 in human myelogenous leukemia
Stavros Manteniotis, Sebastian Wójcik, P. Brauhoff, M. Möllmann +6 more
2016Cell Death Discovery76 citations Open access
Semantic Scholar
Involvement of Toso in activation of monocytes, macrophages, and granulocytes
K. Lang, P. Lang, A. Meryk, A. Pandyra +23 more
2013Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
Semantic Scholar
A novel nonobese diabetic/severe combined immunodeficient xenograft model for chronic lymphocytic leukemia reflects important clinical characteristics of the disease.
J. Dürig, P. Ebeling, F. Grabellus, U. Sorg +8 more
2007Cancer Research72 citations Open access
Semantic Scholar
Loss of TLR2 Worsens Spontaneous Colitis in MDR1A Deficiency through Commensally Induced Pyroptosis
Birgit Ey, Annette Eyking, Magdalena Klepak, N. Salzman +6 more
2013Journal of Immunology62 citations Open access
Semantic Scholar
Deorphanization and characterization of the ectopically expressed olfactory receptor OR51B5 in myelogenous leukemia cells
Stavros Manteniotis, Sebastian Wójcik, J. Göthert, J. Dürig +3 more
2016Cell Death Discovery55 citations Open access
Semantic Scholar
Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities.
T. Schmidt, Mohammad Tauseef, Li-Li Yue, M. Bonini +6 more
2013American Journal of Physiology - Lung cellular and Molecular Physiology55 citations Open access
Semantic Scholar
Expansion of functional personalized cells with specific transgene combinations
Christoph Lipps, Franziska Klein, Tom Wahlicht, Virginia Seiffert +28 more
2018Nature Communications54 citations Open access
Semantic Scholar
CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection
V. Khairnar, V. Duhan, A. Patil, Fan Zhou +17 more
2018Nature Communications54 citations Open access
Semantic Scholar
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
V. Khairnar, V. Duhan, S. K. Maney, N. Honke +24 more
2015Nature Communications52 citations Open access
Semantic Scholar
Acid ceramidase of macrophages traps herpes simplex virus in multivesicular bodies and protects from severe disease
Judith Lang, Patrick S. Bohn, H. Bhat, H. Jastrow +27 more
2020Nature Communications51 citations Open access
Semantic Scholar
Exacerbation of ischemic brain injury in hypercholesterolemic mice is associated with pronounced changes in peripheral and cerebral immune responses.
J. Herz, Sabine I. Hagen, Eileen Bergmüller, Pascal Sabellek +5 more
2014Neurobiology of Disease50 citations Open access
Semantic Scholar
Tal1 regulates osteoclast differentiation through suppression of the master regulator of cell fusion DC‐STAMP
Nadine Courtial, J. J. Smink, Olga N. Kuvardina, A. Leutz +2 more
2012The FASEB Journal43 citations
Semantic Scholar
Expanded CD8+ T cells of murine and human CLL are driven into a senescent KLRG1+ effector memory phenotype
J. Göthert, L. Eisele, L. Klein-Hitpass, S. Weber +6 more
2013Cancer Immunology and Immunotherapy41 citations Open access
Semantic Scholar
Hemovascular Progenitors in the Kidney Require Sphingosine-1-Phosphate Receptor 1 for Vascular Development.
Yan Hu, Minghong Li, J. Göthert, R. A. Gomez +1 more
2016Journal of the American Society of Nephrology40 citations Open access
Semantic Scholar
Pten loss in the bone marrow leads to G-CSF–mediated HSC mobilization
M. Tesio, G. Oser, I. Baccelli, W. Blanco-Bose +4 more
2013Journal of Experimental Medicine39 citations Open access
Semantic Scholar
Deficiency in lymphotoxin β receptor protects from atherosclerosis in apoE-deficient mice.
M. Grandoch, Kathrin Feldmann, J. Göthert, Lena S. Dick +13 more
2015Circulation Research36 citations Open access
Semantic Scholar
NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis.
J. Göthert, R. Brake, Monique F. Smeets, U. Duhrsen +2 more
2007Blood29 citations Open access
Semantic Scholar
Regulation of Arthritis Severity by the Acid Sphingomyelinase
Nadine Beckmann, K. A. Becker, S. Walter, J. Becker +7 more
2017Cellular Physiology and Biochemistry28 citations Open access
Semantic Scholar
Investigating the role of CD38 and functionally related molecular risk factors in the CLL NOD/SCID xenograft model
Semra Aydın, F. Grabellus, L. Eisele, M. Möllmann +9 more
2011European Journal of Haematology24 citations
Semantic Scholar
Kidney Dysfunction Is Associated with Thrombosis and Disease Severity in Myeloproliferative Neoplasms: Implications from the German Study Group for MPN Bioregistry
Judith Gecht, I. Tsoukakis, Kim Kricheldorf, F. Stegelmann +22 more
2021Cancers23 citations Open access
Semantic Scholar
A Phase 2 Study of the LSD1 Inhibitor Img-7289 (bomedemstat) for the Treatment of Advanced Myelofibrosis
H. Gill, A. Yacoub, K. Pettit, T. Bradley +21 more
2021Blood22 citations Open access
Semantic Scholar
Pathological manifestations of Farber disease in a new mouse model
Nadine Beckmann, Stephanie Kadow, F. Schumacher, J. Göthert +11 more
2018Biological chemistry22 citations Open access
Semantic Scholar
Comparison of recognition of symptom burden in MPN between patient- and physician-reported assessment – an intraindividual analysis by the German Study Group for MPN (GSG-MPN)
Kirsi Manz, F. Heidel, Steffen Koschmieder, Rudolf Schlag +17 more
2025Leukemia19 citations Open access
Semantic Scholar
Step-in dosing of bosutinib in pts with chronic phase chronic myeloid leukemia (CML) after second-generation tyrosine kinase inhibitor (TKI) therapy: results of the Bosutinib Dose Optimization (BODO) Study
S. Isfort, Kirsi Manz, Lino L. Teichmann, M. Crysandt +22 more
2023Annals of Hematology18 citations Open access
Semantic Scholar
Hepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in Mice
K. von Wnuck Lipinski, Katherine Sattler, Susann Peters, S. Weske +5 more
2016Journal of Immunology18 citations
Semantic Scholar
Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and CNS Homeostasis
Khiem A. Tran, Xianming Zhang, D. Predescu, Xiao-Jia Huang +5 more
2015Circulation17 citations Open access
Semantic Scholar
A novel mechanism involved in the pathogenesis of Graves ophthalmopathy (GO): clathrin is a possible targeting molecule for inhibiting local immune response in the orbit.
Melissa Meyer zu Hörste, Elena Ströher, U. Berchner-Pfannschmidt, S. Schmitz‐Spanke +5 more
2011Journal of Clinical Endocrinology and Metabolism16 citations Open access
Semantic Scholar
Nuclear factor of activated T-cells, NFATC1, governs FLT3ITD-driven hematopoietic stem cell transformation and a poor prognosis in AML
M. Solovey, Ying Wang, Christian Michel, K. Metzeler +10 more
2019Journal of Hematology & Oncology15 citations Open access
Semantic Scholar
Selective Involvement of Serum Response Factor in Pressure-Induced Myogenic Tone in Resistance Arteries
Kevin Retailleau, B. Toutain, G. Galmiche, C. Fassot +16 more
2013Arteriosclerosis, Thrombosis and Vascular Biology15 citations Open access
Semantic Scholar
A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Advanced Myelofibrosis (MF): Updated Results and Genomic Analyses
K. Pettit, H. Gill, A. Yacoub, T. Bradley +28 more
2022Blood14 citations Open access
Semantic Scholar
Efficacy of Ropeginterferon Alpha 2b in Inducing Treatment Free Remission in Chronic Myeloid Leukemia - an International, Randomized Phase III Trial (ENDURE, CML-IX) of the German CML-Study Group
A. Burchert, S. Saussele, Christian Michel, S. Metzelder +30 more
2022Blood13 citations Open access
Semantic Scholar
A Phase 2 Study of the LSD1 Inhibitor Bomedemstat (IMG-7289) for the Treatment of Essential Thrombocythemia (ET)
H. Gill, F. Palandri, D. Ross, T. Cochrane +21 more
2022Blood13 citations Open access
Semantic Scholar
Updated Results from the German Mpnsg-0212 Combination Trial: Ruxolitinib Plus Pomalidomide in Myelofibrosis with Anemia
F. Stegelmann, S. Koschmieder, S. Isfort, A. Hochhaus +16 more
2019Blood13 citations Open access
Semantic Scholar
How I diagnose and treat patients in the pre-fibrotic phase of primary myelofibrosis (pre-PMF) - practical approaches of a German expert panel discussion in 2024
M. Griesshammer, H. Al-Ali, J. Eckardt, Michael Fiegl +7 more
2025Annals of Hematology12 citations Open access
Semantic Scholar
Distinct Genetically Determined Origins of Myd88/BCL2-Driven Aggressive Lymphoma Rationalize Targeted Therapeutic Intervention Strategies
R. Flümann, Julie Hansen, Benedikt W. Pelzer, P. Nieper +32 more
2022Blood Cancer Discovery12 citations Open access
Semantic Scholar
P1033: A PHASE 2 STUDY OF THE LSD1 INHIBITOR IMG-7289 (BOMEDEMSTAT) FOR THE TREATMENT OF ESSENTIAL THROMBOCYTHEMIA (ET)
F. Palandri, D. Ross, T. Cochrane, C. Tate +24 more
2021HemaSphere12 citations Open access
Semantic Scholar
Defective migration and dysmorphology of neutrophil granulocytes in atypical chronic myeloid leukemia treated with ruxolitinib
L. Bornemann, M. Schuster, S. Schmitz, Charlyn Sobczak +6 more
2020BMC Cancer10 citations Open access
Semantic Scholar
P1051: A PHASE 2 STUDY OF IMG-7289 (BOMEDEMSTAT) IN PATIENTS WITH ADVANCED MYELOFIBROSIS
H. Gill, A. Yacoub, K. Pettit, T. Bradley +32 more
2022HemaSphere9 citations Open access
Semantic Scholar
Identification of cardiac hemo-vascular precursors and their requirement of sphingosine-1-phosphate receptor 1 for heart development
Yan Hu, Brian C. Belyea, Minghong Li, J. Göthert +2 more
2017Scientific Reports8 citations Open access
Semantic Scholar

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