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C. Wellington · SciRah

Researcher profile · Semantic Scholar

C. Wellington

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C. Wellington — researcher profile on SciRah

h-index: 61
Works: 176
Citations: 15K

Most-cited papers

Vascular Contributions to Cognitive Impairment and Dementia Including Alzheimer’s Disease
H. Snyder, R. Corriveau, S. Craft, James E. Faber +16 more
2014Alzheimer's & Dementia606 citations Open access
Semantic Scholar
White matter hyperintensities in vascular contributions to cognitive impairment and dementia (VCID): Knowledge gaps and opportunities
J. Alber, S. Alladi, H. Bae, David A. Barton +49 more
2019Alzheimer's & Dementia410 citations Open access
Semantic Scholar
HDL and cholesterol handling in the brain.
C. Vitali, C. Wellington, L. Calabresi
2014Cardiovascular Research242 citations
Semantic Scholar
Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome
Lu-Ke Y. C. Chen, R. Hoiland, S. Stukas, C. Wellington +1 more
2020European Respiratory Journal215 citations Open access
Semantic Scholar
Vascular contributions to cognitive impairment and dementia (VCID): A report from the 2018 National Heart, Lung, and Blood Institute and National Institute of Neurological Disorders and Stroke Workshop
B. Zlokovic, R. Gottesman, Kenneth E. Bernstein, S. Seshadri +22 more
2020Alzheimer's & Dementia208 citations Open access
Semantic Scholar
Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes
J. England, Alym Abdulla, C. Biggs, A. Lee +7 more
2020Blood reviews170 citations Open access
Semantic Scholar
Cholesterol Defect Is Marked across Multiple Rodent Models of Huntington's Disease and Is Manifest in Astrocytes
M. Valenza, V. Leoni, J. Karasinska, Lara Petricca +11 more
2010Journal of Neuroscience162 citations Open access
Semantic Scholar
Cerebral microvascular injury: a potentially treatable endophenotype of traumatic brain injury-induced neurodegeneration
D. Sandsmark, A. Bashir, C. Wellington, R. Diaz-Arrastia
2019Neuron156 citations Open access
Semantic Scholar
The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19
R. Hoiland, Nicholas A. Fergusson, Anish R. Mitra, D. Griesdale +10 more
2020Blood Advances155 citations Open access
Semantic Scholar
Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired β-Cell Function
J. Kruit, N. Wijesekara, C. Westwell-Roper, T. Vanmierlo +9 more
2012Diabetes124 citations Open access
Semantic Scholar
Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective
D. Namjoshi, Craig A Good, Wai-Hang Cheng, W. Panenka +3 more
2013Disease Models & Mechanisms113 citations Open access
Semantic Scholar
HDL from an Alzheimer's disease perspective
E. Button, J. Robert, T. M. Caffrey, Jian-Jia Fan +2 more
2019Current Opinion in Lipidology95 citations Open access
Semantic Scholar
ABCA1 influences neuroinflammation and neuronal death.
J. Karasinska, W. de Haan, S. Franciosi, P. Ruddle +7 more
2013Neurobiology of Disease94 citations Open access
Semantic Scholar
Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration)
D. Namjoshi, Wai-Hang Cheng, A. Bashir, Anna Wilkinson +7 more
2017Experimental Neurology89 citations Open access
Semantic Scholar
Intravenously Injected Human Apolipoprotein A‐I Rapidly Enters the Central Nervous System via the Choroid Plexus
S. Stukas, J. Robert, Michael Lee, Iva Kulic +14 more
2014Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease87 citations Open access
Semantic Scholar
High-density lipoproteins and cerebrovascular integrity in Alzheimer's disease.
S. Stukas, J. Robert, C. Wellington
2014Cell Metabolism87 citations
Semantic Scholar
Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-beta.
R. Takechi, Susan Galloway, Menuka M. S. Pallebage-Gamarallage, C. Wellington +3 more
2010British Journal of Nutrition86 citations Open access
Semantic Scholar
Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice.
J. Robert, S. Stukas, E. Button, Wai-Hang Cheng +6 more
2016Biochimica et Biophysica Acta78 citations Open access
Semantic Scholar
Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post–Cardiac Arrest
R. Hoiland, P. Ainslie, C. Wellington, Jennifer G. Cooper +10 more
2021Circulation Research68 citations Open access
Semantic Scholar
Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome
Lu-Ke Y. C. Chen, C. Biggs, S. Jamal, S. Stukas +2 more
2021Cell Reports Medicine65 citations Open access
Semantic Scholar
High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture
J. Robert, E. Button, S. Stukas, Guilaine K. Boyce +12 more
2017Molecular Neurodegeneration61 citations Open access
Semantic Scholar
The Liver X Receptor Agonist GW3965 Improves Recovery from Mild Repetitive Traumatic Brain Injury in Mice Partly through Apolipoprotein E
D. Namjoshi, Georgina Martin, J. Donkin, Anna Wilkinson +7 more
2013PLoS ONE60 citations Open access
Semantic Scholar
CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice
Wai-Hang Cheng, Kris M. Martens, A. Bashir, Honor Cheung +9 more
2019Alzheimer's Research & Therapy58 citations Open access
Semantic Scholar
ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice
E. Button, Guilaine K. Boyce, Anna Wilkinson, S. Stukas +6 more
2019Alzheimer's Research & Therapy56 citations Open access
Semantic Scholar
modCHIMERA: a novel murine closed-head model of moderate traumatic brain injury
A. Sauerbeck, C. Fanizzi, J. Kim, M. Gangolli +4 more
2018Scientific Reports55 citations Open access
Semantic Scholar
Age at injury and genotype modify acute inflammatory and neurofilament‐light responses to mild CHIMERA traumatic brain injury in wild‐type and APP/PS1 mice
Wai-Hang Cheng, S. Stukas, Kris M. Martens, D. Namjoshi +6 more
2018Experimental Neurology50 citations
Semantic Scholar
Assessing the importance of interleukin-6 in COVID-19
Lu-Ke Y. C. Chen, R. Hoiland, S. Stukas, C. Wellington +1 more
2021The Lancet Respiratory Medicine46 citations Open access
Semantic Scholar
Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis.
A. Bashir, Zelalem A. Abebe, Kurt A. McInnes, E. Button +9 more
2019Experimental Neurology45 citations
Semantic Scholar
A Rationally Designed Humanized Antibody Selective for Amyloid Beta Oligomers in Alzheimer’s Disease
E. Gibbs, J. Silverman, Bei-Bei Zhao, Xu-Biao Peng +6 more
2019Scientific Reports42 citations Open access
Semantic Scholar
Review of Design Considerations for Brain-on-a-Chip Models
T. Cameron, Tanya Bennet, Elyn M. Rowe, Mehwish Anwer +2 more
2021Micromachines41 citations Open access
Semantic Scholar
Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.
Cole Vonder Haar, Kris M. Martens, A. Bashir, Kurt A. McInnes +9 more
2019Experimental Neurology41 citations
Semantic Scholar
Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway
Jian-Jia Fan, Rui-Qiao Zhao, Cameron C. Parro, Wen-Chen Zhao +14 more
2018Journal of Lipid Research41 citations Open access
Semantic Scholar
Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019
Jennifer G. Cooper, S. Stukas, R. Hoiland, Nicholas A. Fergusson +7 more
2020Critical Care Explorations40 citations Open access
Semantic Scholar
Frontal Traumatic Brain Injury Increases Impulsive Decision Making in Rats: A Potential Role for the Inflammatory Cytokine Interleukin-12
Cole Vonder Haar, Kris M. Martens, Lara-Kirstie Riparip, S. Rosi +2 more
2017Journal of Neurotrauma40 citations Open access
Semantic Scholar
Blood-based traumatic brain injury biomarkers – Clinical utilities and regulatory pathways in the United States, Europe and Canada
Kevin K. W. Wang, J. C. Muñoz Pareja, S. Mondello, R. Diaz-Arrastia +14 more
2021Expert Review of Molecular Diagnostics39 citations
Semantic Scholar
The pleiotropic vasoprotective functions of high density lipoproteins (HDL)
Guilaine K. Boyce, E. Button, Sonja Soo, C. Wellington
2017Journal of Biomedical Research39 citations Open access
Semantic Scholar
Chronic Exposure to Androgenic-Anabolic Steroids Exacerbates Axonal Injury and Microgliosis in the CHIMERA Mouse Model of Repetitive Concussion
D. Namjoshi, Wai-Hang Cheng, M. Carr, Kris M. Martens +5 more
2016PLoS ONE39 citations Open access
Semantic Scholar
Defining an Analytic Framework to Evaluate Quantitative MRI Markers of Traumatic Axonal Injury: Preliminary Results in a Mouse Closed Head Injury Model
M. Haber, E. Hutchinson, N. Sadeghi, Wai-Hang Cheng +6 more
2017eNeuro38 citations Open access
Semantic Scholar
Distinct roles for metalloproteinases during traumatic brain injury.
Si Zhang, Luba Kojic, M. Tsang, Parampal Grewal +6 more
2016Neurochemistry International38 citations
Semantic Scholar
Using metabolomics to predict severe traumatic brain injury outcome (GOSE) at 3 and 12 months
M. Banoei, C. Lee, Jamie Hutchison, William Panenka +4 more
2023Critical Care37 citations Open access
Semantic Scholar
Amelioration of COVID‐19‐related cytokine storm syndrome: parallels to chimeric antigen receptor‐T cell cytokine release syndrome
R. Hoiland, S. Stukas, Jennifer G. Cooper, S. Thiara +8 more
2020British Journal of Haematology35 citations Open access
Semantic Scholar
Characterisation of serum total tau following paediatric traumatic brain injury: a case-control study.
S. Stukas, V. Higgins, H. Frndova, J. Gill +14 more
2019The Lancet Child & Adolescent Health31 citations
Semantic Scholar
Relation between plasma and brain lipids
C. Wellington, R. Frikke-Schmidt
2016Current Opinion in Lipidology28 citations
Semantic Scholar
Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality
Alexander Leatherdale, S. Stukas, Victor Lei, H. West +7 more
2022Medical Microbiology and Immmunology27 citations Open access
Semantic Scholar
Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
J. Robert, E. Button, Emma M. Martin, Luke McAlary +9 more
2020Molecular Neurodegeneration27 citations Open access
Semantic Scholar
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury
E. Button, Wai-Hang Cheng, Carlos J. Barron, Honor Cheung +9 more
2021Alzheimer's Research & Therapy26 citations Open access
Semantic Scholar
Military Related Risk Factors for Dementia
H. Snyder, Roxana O. O. Carare, S. DeKosky, M. D. de Leon +17 more
2018Alzheimer's & Dementia26 citations Open access
Semantic Scholar
LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function
M. Hoekstra, S. Korporaal, R. J. van der Sluis, V. Hirsch-Reinshagen +5 more
2013Journal of Lipid Research26 citations Open access
Semantic Scholar
An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia
Jian-Jia Fan, S. Stukas, Charmaine Wong, Jennifer Y Chan +6 more
2011Journal of Lipid Research25 citations Open access
Semantic Scholar
The Association of Inflammatory Cytokines in the Pulmonary Pathophysiology of Respiratory Failure in Critically Ill Patients With Coronavirus Disease 2019
S. Stukas, R. Hoiland, Jennifer G. Cooper, S. Thiara +15 more
2020Critical Care Explorations24 citations Open access
Semantic Scholar

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