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S. Stukas · SciRah

Researcher profile · Semantic Scholar

S. Stukas

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S. Stukas — researcher profile on SciRah

h-index: 26
Works: 78
Citations: 2,103

Most-cited papers

Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome
Lu-Ke Y. C. Chen, R. Hoiland, S. Stukas, C. Wellington +1 more
2020European Respiratory Journal215 citations Open access
Semantic Scholar
ATP-binding Cassette Transporter A1 Mediates the Beneficial Effects of the Liver X Receptor Agonist GW3965 on Object Recognition Memory and Amyloid Burden in Amyloid Precursor Protein/Presenilin 1 Mice*
J. Donkin, S. Stukas, V. Hirsch-Reinshagen, D. Namjoshi +6 more
2010Journal of Biological Chemistry193 citations Open access
Semantic Scholar
The association of ABO blood group with indices of disease severity and multiorgan dysfunction in COVID-19
R. Hoiland, Nicholas A. Fergusson, Anish R. Mitra, D. Griesdale +10 more
2020Blood Advances155 citations Open access
Semantic Scholar
ABCA1 influences neuroinflammation and neuronal death.
J. Karasinska, W. de Haan, S. Franciosi, P. Ruddle +7 more
2013Neurobiology of Disease94 citations Open access
Semantic Scholar
Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration)
D. Namjoshi, Wai-Hang Cheng, A. Bashir, Anna Wilkinson +7 more
2017Experimental Neurology89 citations Open access
Semantic Scholar
Intravenously Injected Human Apolipoprotein A‐I Rapidly Enters the Central Nervous System via the Choroid Plexus
S. Stukas, J. Robert, Michael Lee, Iva Kulic +14 more
2014Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease87 citations Open access
Semantic Scholar
High-density lipoproteins and cerebrovascular integrity in Alzheimer's disease.
S. Stukas, J. Robert, C. Wellington
2014Cell Metabolism87 citations
Semantic Scholar
Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice.
J. Robert, S. Stukas, E. Button, Wai-Hang Cheng +6 more
2016Biochimica et Biophysica Acta78 citations Open access
Semantic Scholar
Brain Hypoxia Is Associated With Neuroglial Injury in Humans Post–Cardiac Arrest
R. Hoiland, P. Ainslie, C. Wellington, Jennifer G. Cooper +10 more
2021Circulation Research68 citations Open access
Semantic Scholar
Soluble interleukin-6 receptor in the COVID-19 cytokine storm syndrome
Lu-Ke Y. C. Chen, C. Biggs, S. Jamal, S. Stukas +2 more
2021Cell Reports Medicine65 citations Open access
Semantic Scholar
High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture
J. Robert, E. Button, S. Stukas, Guilaine K. Boyce +12 more
2017Molecular Neurodegeneration61 citations Open access
Semantic Scholar
The Liver X Receptor Agonist GW3965 Improves Recovery from Mild Repetitive Traumatic Brain Injury in Mice Partly through Apolipoprotein E
D. Namjoshi, Georgina Martin, J. Donkin, Anna Wilkinson +7 more
2013PLoS ONE60 citations Open access
Semantic Scholar
CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice
Wai-Hang Cheng, Kris M. Martens, A. Bashir, Honor Cheung +9 more
2019Alzheimer's Research & Therapy58 citations Open access
Semantic Scholar
Age specific reference intervals for plasma biomarkers of neurodegeneration and neurotrauma in a Canadian population.
Jennifer G. Cooper, S. Stukas, Mohammad Ghodsi, Nyra Ahmed +3 more
2023Clinical Biochemistry57 citations
Semantic Scholar
ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice
E. Button, Guilaine K. Boyce, Anna Wilkinson, S. Stukas +6 more
2019Alzheimer's Research & Therapy56 citations Open access
Semantic Scholar
Age at injury and genotype modify acute inflammatory and neurofilament‐light responses to mild CHIMERA traumatic brain injury in wild‐type and APP/PS1 mice
Wai-Hang Cheng, S. Stukas, Kris M. Martens, D. Namjoshi +6 more
2018Experimental Neurology50 citations
Semantic Scholar
Association of CSF and Serum Neurofilament Light and Glial Fibrillary Acidic Protein, Injury Severity, and Outcome in Spinal Cord Injury
S. Stukas, Jennifer G. Cooper, J. Gill, N. Fallah +20 more
2023Neurology46 citations Open access
Semantic Scholar
Assessing the importance of interleukin-6 in COVID-19
Lu-Ke Y. C. Chen, R. Hoiland, S. Stukas, C. Wellington +1 more
2021The Lancet Respiratory Medicine46 citations Open access
Semantic Scholar
Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis.
A. Bashir, Zelalem A. Abebe, Kurt A. McInnes, E. Button +9 more
2019Experimental Neurology45 citations
Semantic Scholar
Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory tubercle and generates white matter inflammation, tau phosphorylation and degeneration.
Cole Vonder Haar, Kris M. Martens, A. Bashir, Kurt A. McInnes +9 more
2019Experimental Neurology41 citations
Semantic Scholar
Quantification of Neurological Blood-Based Biomarkers in Critically Ill Patients With Coronavirus Disease 2019
Jennifer G. Cooper, S. Stukas, R. Hoiland, Nicholas A. Fergusson +7 more
2020Critical Care Explorations40 citations Open access
Semantic Scholar
Amelioration of COVID‐19‐related cytokine storm syndrome: parallels to chimeric antigen receptor‐T cell cytokine release syndrome
R. Hoiland, S. Stukas, Jennifer G. Cooper, S. Thiara +8 more
2020British Journal of Haematology35 citations Open access
Semantic Scholar
Characterisation of serum total tau following paediatric traumatic brain injury: a case-control study.
S. Stukas, V. Higgins, H. Frndova, J. Gill +14 more
2019The Lancet Child & Adolescent Health31 citations
Semantic Scholar
Neuroinflammation and the immune system in hypoxic ischaemic brain injury pathophysiology after cardiac arrest
M. Sekhon, S. Stukas, V. Hirsch-Reinshagen, S. Thiara +5 more
2023Journal of Physiology27 citations
Semantic Scholar
Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality
Alexander Leatherdale, S. Stukas, Victor Lei, H. West +7 more
2022Medical Microbiology and Immmunology27 citations Open access
Semantic Scholar
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury
E. Button, Wai-Hang Cheng, Carlos J. Barron, Honor Cheung +9 more
2021Alzheimer's Research & Therapy26 citations Open access
Semantic Scholar
An ABCA1-independent pathway for recycling a poorly lipidated 8.1 nm apolipoprotein E particle from glia
Jian-Jia Fan, S. Stukas, Charmaine Wong, Jennifer Y Chan +6 more
2011Journal of Lipid Research25 citations Open access
Semantic Scholar
Pediatric reference intervals for serum neurofilament light and glial fibrillary acidic protein using the Canadian Laboratory Initiative on Pediatric Reference Intervals (CALIPER) cohort
S. Stukas, Jennifer G. Cooper, V. Higgins, Daniel T. Holmes +2 more
2023Clinical Chemistry and Laboratory Medicine24 citations Open access
Semantic Scholar
The Association of Inflammatory Cytokines in the Pulmonary Pathophysiology of Respiratory Failure in Critically Ill Patients With Coronavirus Disease 2019
S. Stukas, R. Hoiland, Jennifer G. Cooper, S. Thiara +15 more
2020Critical Care Explorations24 citations Open access
Semantic Scholar
The LXR agonist GW3965 increases apoA-I protein levels in the central nervous system independent of ABCA1.
S. Stukas, Sharon May, Anna Wilkinson, Jeniffer Y. Chan +2 more
2012Biochimica et Biophysica Acta24 citations
Semantic Scholar
A Rational Structured Epitope Defines a Distinct Subclass of Toxic Amyloid-beta Oligomers.
J. Silverman, E. Gibbs, Xu-Biao Peng, Kris M. Martens +14 more
2018ACS Chemical Neuroscience21 citations Open access
Semantic Scholar
Serum neurofilament light chain correlates with myelin and axonal magnetic resonance imaging markers in multiple sclerosis.
Jackie T. Yik, P. Becquart, J. Gill, J. Petkau +14 more
2021Multiple Sclerosis and Related Disorders18 citations
Semantic Scholar
Characterization of Cerebrospinal Fluid Ubiquitin C-Terminal Hydrolase L1 as a Biomarker of Human Acute Traumatic Spinal Cord Injury
S. Stukas, J. Gill, Jennifer G. Cooper, L. Belanger +18 more
2021Journal of Neurotrauma17 citations
Semantic Scholar
An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
J. Robert, N. L. Weilinger, Li-ping Cao, Stefano Cataldi +11 more
2020Molecular Neurodegeneration17 citations Open access
Semantic Scholar
Characterizing the physiology of circulatory arrest in humans
Jordan D. Bird, Laura Hornby, Veronica Hirsch-Reinshagen, Chloe P. Allen +39 more
2025Nature Medicine12 citations Open access
Semantic Scholar
APOE ε4 carrier status modifies plasma p‐tau181 concentrations in cognitively healthy super‐seniors
Jennifer G. Cooper, Mohammad Ghodsi, S. Stukas, Stephen Leach +2 more
2024Alzheimer's & Dementia12 citations Open access
Semantic Scholar
Plasma biomarkers distinguish Boston Criteria 2.0 cerebral amyloid angiopathy from healthy controls
Ryan T. Muir, S. Stukas, Jennifer G. Cooper, Andrew E. Beaudin +11 more
2024medRxiv10 citations Open access
Semantic Scholar
Clearance of beta-amyloid is facilitated by apolipoprotein E and circulating high-density lipoproteins in bioengineered human vessels
J. Robert, E. Button, B. Yuen, M. Gilmour +6 more
2017eLife10 citations Open access
Semantic Scholar
Reduced fixed dose tocilizumab 400 mg IV compared to weight-based dosing in critically ill patients with COVID-19: A before-after cohort study
S. Stukas, G. Goshua, Angus Kinkade, R. Grey +12 more
2022The Lancet Regional Health - Americas9 citations Open access
Semantic Scholar
Prognostic peripheral blood biomarkers at ICU admission predict COVID-19 clinical outcomes
M. Messing, M. Sekhon, M. Hughes, S. Stukas +11 more
2022Frontiers in Immunology8 citations Open access
Semantic Scholar
Diffusely abnormal white matter in clinically isolated syndrome is associated with parenchymal loss and elevated neurofilament levels.
I. Vavasour, P. Becquart, J. Gill, G. Zhao +14 more
2021Multiple Sclerosis and Related Disorders7 citations
Semantic Scholar
LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice[S]
S. Stukas, L. Freeman, Michael Lee, Anna Wilkinson +7 more
2014Journal of Lipid Research7 citations Open access
Semantic Scholar
Prognostic value of plasma biomarkers for informing clinical trial design in mild-to-moderate Alzheimer’s disease
Yuqi Qiu, Diane M. Jacobs, Karen Messer, D. Salmon +61 more
2025Alzheimer's Research & Therapy6 citations Open access
Semantic Scholar
O3-01-02: CHIMERA REPETITIVE MILD TRAUMATIC BRAIN INJURY INDUCES CHRONIC BEHAVIORAL AND NEUROPATHOLOGICAL PHENOTYPES IN WILD-TYPE AND APP/PS1 MICE
Wai-Hang Cheng, Kris M. Martens, A. Bashir, Honor Cheung +11 more
2019Alzheimer's & Dementia3 citations
Semantic Scholar
Lipids and Lipoproteins in Alzheimer’s Disease
S. Stukas, Iva Kulic, Shahab Zareyan, C. Wellington
20153 citations Open access
Semantic Scholar
1 ATP-BINDING CASSETTE TRANSPORTER A 1 MEDIATES THE BENEFICIAL EFFECTS OF THE LIVER-X-RECEPTOR AGONIST GW 3965 ON OBJECT RECOGNITION MEMORY AND AMYLOID BURDEN IN APP / PS 1 MICE
J. Donkin, S. Stukas, V. Hirsch-Reinshagen, D. Namjoshi +6 more
20103 citations
Semantic Scholar
An in vitro bioengineered model of the human arterial neurovascular unit to study neurodegenerative diseases
J. Robert, N. L. Weilinger, L. Cao, Stefano Cataldi +11 more
2020Molecular Neurodegeneration2 citations Open access
Semantic Scholar
P4-164: APOA-I DEFICIENCY INCREASES CORTICAL AMYLOID DEPOSITION, CEREBRAL AMYLOID ANGIOPATHY, CORTICAL AND HIPPOCAMPAL ASTROGLIOSIS AND AMYLOID-ASSOCIATED ASTROCYTE REACTIVITY IN APP/PS1 MICE
E. Button, Guilaine K. Boyce, Anna Wilkinson, S. Stukas +4 more
2019Alzheimer's & Dementia2 citations
Semantic Scholar
Biases and consistency of different assay methods for neurological biomarkers using Quanterix single-molecule-array technology: A secondary analysis method comparison study
K. Go, J. Hutchison, Kevin Wang, T. Karikari +6 more
2025NeuroMarkers1 citations Open access
Semantic Scholar
Advocates, Academics, Survivors and Clinicians to END Intimate Partner Violence (ASCEND-IPV) initiative: a prospective observational case–control study protocol to identify plasma biomarkers of intimate partner violence (IPV)-caused brain injury (BI)
M. Harper, Kelly A. McKinney, Caroline McLennan, S. Adhikari +21 more
2025BMJ Open1 citations Open access
Semantic Scholar

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Wai-Hang Cheng×9

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