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W. de Haan · SciRah

Researcher profile · Semantic Scholar

W. de Haan

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W. de Haan — researcher profile on SciRah

h-index: 27
Works: 84
Citations: 3,127

Most-cited papers

Influenza Virus in Human Exhaled Breath: An Observational Study
P. Fabian, J. Mcdevitt, W. de Haan, Rita O. P. Fung +4 more
2008PLoS ONE523 citations Open access
Semantic Scholar
Characterization of cereal toxicity for celiac disease patients based on protein homology in grains.
L. Vader, D. Stepniak, Evelien M. Bunnik, Y. Kooy +4 more
2003Gastroenterology254 citations Open access
Semantic Scholar
Cholesteryl Ester Transfer Protein Decreases High-Density Lipoprotein and Severely Aggravates Atherosclerosis in APOE*3-Leiden Mice
M. Westerterp, C. C. van der Hoogt, W. de Haan, E. Offerman +4 more
2006Arteriosclerosis, Thrombosis and Vascular Biology250 citations Open access
Semantic Scholar
Niacin Increases HDL by Reducing Hepatic Expression and Plasma Levels of Cholesteryl Ester Transfer Protein in APOE*3Leiden.CETP Mice
J. V. D. van der Hoorn, W. de Haan, J. Berbée, L. Havekes +3 more
2008Arteriosclerosis, Thrombosis and Vascular Biology192 citations Open access
Semantic Scholar
Predicting extrathoracic deposition from dry powder inhalers
W. de Haan, Warren H. Finlay
2004139 citations Open access
Semantic Scholar
Loss of Both ABCA1 and ABCG1 Results in Increased Disturbances in Islet Sterol Homeostasis, Inflammation, and Impaired β-Cell Function
J. Kruit, N. Wijesekara, C. Westwell-Roper, T. Vanmierlo +9 more
2012Diabetes124 citations Open access
Semantic Scholar
Loss of Cyp8b1 Improves Glucose Homeostasis by Increasing GLP-1
Achint Kaur, J. Patankar, W. de Haan, P. Ruddle +5 more
2014Diabetes116 citations
Semantic Scholar
In Vitro Monodisperse Aerosol Deposition in a Mouth and Throat with Six Different Inhalation Devices
W. de Haan, W. H. Finlay
2001Journal of Aerosol Medicine116 citations
Semantic Scholar
Torcetrapib Does Not Reduce Atherosclerosis Beyond Atorvastatin and Induces More Proinflammatory Lesions Than Atorvastatin
W. de Haan, J. de Vries-van der Weij, J. V. D. van der Hoorn, T. Gautier +7 more
2008Circulation105 citations Open access
Semantic Scholar
Regulation of ABCA1 Protein Expression and Function in Hepatic and Pancreatic Islet Cells by miR-145
Martin H. Kang, Lin-hua Zhang, N. Wijesekara, W. de Haan +3 more
2013Arteriosclerosis, Thrombosis and Vascular Biology101 citations Open access
Semantic Scholar
Fenofibrate increases HDL-cholesterol by reducing cholesteryl ester transfer protein expression Published, JLR Papers in Press, May 24, 2007.
C. C. van der Hoogt, W. de Haan, M. Westerterp, M. Hoekstra +6 more
2007Journal of Lipid Research99 citations Open access
Semantic Scholar
ABCA1 in adipocytes regulates adipose tissue lipid content, glucose tolerance, and insulin sensitivity[S]
W. de Haan, A. Bhattacharjee, P. Ruddle, Martin H. Kang +1 more
2014Journal of Lipid Research94 citations Open access
Semantic Scholar
ABCA1 influences neuroinflammation and neuronal death.
J. Karasinska, W. de Haan, S. Franciosi, P. Ruddle +7 more
2013Neurobiology of Disease94 citations Open access
Semantic Scholar
Atorvastatin increases HDL cholesterol by reducing CETP expression in cholesterol-fed APOE*3-Leiden.CETP mice.
W. de Haan, C. C. van der Hoogt, M. Westerterp, M. Hoekstra +6 more
2008Atherosclerosis92 citations Open access
Semantic Scholar
Restoration of High-Density Lipoprotein Levels by Cholesteryl Ester Transfer Protein Expression in Scavenger Receptor Class B Type I (SR-BI) Knockout Mice Does Not Normalize Pathologies Associated With SR-BI Deficiency
R. B. Hildebrand, Bart Lammers, I. Meurs, S. Korporaal +11 more
2010Arteriosclerosis, Thrombosis and Vascular Biology62 citations Open access
Semantic Scholar
Bexarotene induces dyslipidemia by increased very low-density lipoprotein production and cholesteryl ester transfer protein-mediated reduction of high-density lipoprotein.
J. de Vries-van der Weij, W. de Haan, Li-Hui Hu, Maarten Kuif +7 more
2009Endocrinology57 citations
Semantic Scholar
Endogenous apoC-I increases hyperlipidemia in apoE-knockout mice by stimulating VLDL production and inhibiting LPL Published, JLR Papers in Press, March 14, 2006.
M. Westerterp, W. de Haan, J. Berbée, L. Havekes +1 more
2006Journal of Lipid Research57 citations Open access
Semantic Scholar
Simulation of Particle Deposition in an Idealized Mouth with Different Small Diameter Inlets
E. Matida, W. de Haan, Warren H. Finlay, Carlos F. Lange
200351 citations Open access
Semantic Scholar
Unraveling the transcriptional determinants of Liver Sinusoidal Endothelial Cell specialization.
W. de Haan, C. Øie, Mohammed Benkheil, Wouter Dheedene +9 more
2020American Journal of Physiology - Gastrointestinal and Liver Physiology50 citations Open access
Semantic Scholar
Tolerogenic nanoparticles mitigate the formation of anti-drug antibodies against pegylated uricase in patients with hyperuricemia
E. Sands, A. Kivitz, W. de Haan, S. Leung +2 more
2022Nature Communications48 citations Open access
Semantic Scholar
Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis
W. de Haan, Wouter Dheedene, K. Apelt, Sofiane Décombas-Deschamps +23 more
2021Cardiovascular Research47 citations Open access
Semantic Scholar
Important Role for Bone Marrow–Derived Cholesteryl Ester Transfer Protein in Lipoprotein Cholesterol Redistribution and Atherosclerotic Lesion Development in LDL Receptor Knockout Mice
M. Van Eck, D. Ye, R. B. Hildebrand, J. Kruijt +6 more
2007Circulation Research46 citations Open access
Semantic Scholar
PXR agonism decreases plasma HDL levels in ApoE3-Leiden.CETP mice.
W. de Haan, J. de Vries-van der Weij, I. Mol, M. Hoekstra +5 more
2009Biochimica et Biophysica Acta44 citations
Semantic Scholar
Apolipoprotein CI aggravates atherosclerosis development in ApoE-knockout mice despite mediating cholesterol efflux from macrophages.
M. Westerterp, M. Van Eck, W. de Haan, E. Offerman +3 more
2007Atherosclerosis37 citations Open access
Semantic Scholar
Apolipoprotein CI inhibits scavenger receptor BI and increases plasma HDL levels in vivo.
W. de Haan, Ruud Out, J. Berbée, C. C. van der Hoogt +6 more
2008Biochemical and Biophysical Research Communications - BBRC33 citations
Semantic Scholar
Characteristics of exhaled particle production in healthy volunteers: possible implications for infectious disease transmission
F. Wurie, O. le Polain de Waroux, Matthew Brande, W. de Haan +5 more
2013F1000Research31 citations Open access
Semantic Scholar
Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice[S]
T. Gautier, W. de Haan, J. Grober, D. Ye +13 more
2013Journal of Lipid Research28 citations Open access
Semantic Scholar
Direct intracerebral delivery of a miR-33 antisense oligonucleotide into mouse brain increases brain ABCA1 expression. [Corrected].
A. Jan, J. Karasinska, Martin H. Kang, W. de Haan +6 more
2015Neuroscience Letters27 citations
Semantic Scholar
Phase 2 Dose-Finding Study in Patients with Gout Using SEL-212, a Novel PEGylated Uricase (SEL-037) Combined with Tolerogenic Nanoparticles (SEL-110)
A. Kivitz, W. de Haan, R. Azeem, Justin Park +9 more
2023Rheumatology and Therapy23 citations Open access
Semantic Scholar
The COMPARE head-to-head, randomized controlled trial of SEL-212 (pegadricase plus rapamycin-containing nanoparticle, ImmTOR™) versus pegloticase for refractory gout
H. Baraf, P. Khanna, A. Kivitz, V. Strand +7 more
2023Rheumatology21 citations Open access
Semantic Scholar
Pioglitazone Decreases Plasma Cholesteryl Ester Transfer Protein Mass, Associated With a Decrease in Hepatic Triglyceride Content, in Patients With Type 2 Diabetes
J. Jonker, Ya-Nan Wang, W. de Haan, M. Diamant +8 more
2010Diabetes Care21 citations Open access
Semantic Scholar
Hepatic ABCA1 Expression Improves β-Cell Function and Glucose Tolerance
W. de Haan, J. Karasinska, P. Ruddle, M. Hayden
2014Diabetes20 citations
Semantic Scholar
The Hyplip2 locus causes hypertriglyceridemia by decreased clearance of triglyceridess⃞ Published, JLR Papers in Press, July 3, 2007.
C. Moen, A. Tholens, P. Voshol, W. de Haan +7 more
2007Journal of Lipid Research18 citations Open access
Semantic Scholar
Influenza virus in human exhaled breath
M. Fabian, J. Mcdevitt, W. de Haan, Rop Fung +4 more
200815 citations
Semantic Scholar
A New Natural Defense Against Airborne Pathogens
D. Edwards, A. Hickey, R. Batycky, L. Griel +11 more
2020QRB Discovery14 citations Open access
Semantic Scholar
Formulation Characterization of a Novel Levofloxacin Pulmonary Dry Powder Drug Delivery Technology
Diana Manzanedo, M. Brande, S. Kramer, L. W. Yee +4 more
201210 citations
Semantic Scholar
Pulmonary and Regional Deposition of Nebulized and Dry Powder Aerosols in Ferrets
P. Kuehl, Ramesh Chand, J. McDonald, D. Hava +1 more
2019AAPS PharmSciTech9 citations
Semantic Scholar
Pulmonary delivery of anti-contagion aerosol to diminish exhaled bioaerosols and airborne infectious disease
R. Clarke, J. Katstra, J. Man, W. de Haan +2 more
20059 citations
Semantic Scholar
ABCA 1 in adipocytes regulates adipose tissue lipid content , glucose tolerance , and insulin sensitivity
W. de Haan, A. Bhattacharjee, P. Ruddle, Martin H. Kang +1 more
20148 citations
Semantic Scholar
LB0002 SAFETY & EFFICACY OF SEL-212 IN PATIENTS WITH GOUT REFRACTORY TO COVENTIONAL TREATMENT: OUTCOMES FROM TWO RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED, MULTICENTER PHASE III STUDIES
H. Baraf, A. Kivitz, S. Rhodes, S. Leung +8 more
2023Annals of the Rheumatic Diseases6 citations Open access
Semantic Scholar
Corrigendum to “Direct intracerebral delivery of a miR-33 antisense oligonucleotide into mouse brain increases brain ABCA1 expression’’ [Neuroscience Letters 598 (2015) 66–72]
A. Jan, J. Karasinska, Martin H. Kang, W. de Haan +6 more
20156 citations
Semantic Scholar
Direct intracerebral delivery of a miR-33 antisense oligonucleotide into mouse brain increases brain ABCA1 expression (vol 598, pg 66, 2015)
A. Jan, J. Karasinska, Martin H. Kang, W. de Haan +6 more
20156 citations
Semantic Scholar
Quantum sensing of free radicals in macrophages reveals early autophagy-lysosome regulation in an atherosclerosis cell model
Siyu Fan, Han Gao, Wesley Nieuwhof, Thomas Mulder +9 more
2025Redox Biology5 citations Open access
Semantic Scholar
SAT0402 SEL-212 PHASE 2 CLINICAL STUDY IN SYMPTOMATIC GOUT PATIENTS: IMMTOR TOLEROGENIC NANOPARTICLES COMBINED WITH PEGADRICASE MITIGATES IMMUNOGENICITY AND ENABLES SUSTAINED REDUCTION OF SERUM URIC ACID LEVELS, LOW RATE OF GOUT FLARES AND MONTHLY DOSING
S. Smoliński, A. Kivitz, W. de Haan, Lloyd P. M. Johnston +2 more
2019Saturday, 15 June 20195 citations Open access
Semantic Scholar
Formulation and In Vitro Characterization of a Novel Dry Powder Drug Delivery Technology
Jean C. Sung, Diana Manzanedo, Anson T. Ku, J. Kenyon +3 more
20114 citations
Semantic Scholar
Loss of endothelial ZEB2 in mice attenuates steatosis early during metabolic dysfunction-associated steatotic liver disease
Wouter Dheedene, Stefaan Verhulst, Louise Demuynck, Bram Callewaert +16 more
2025Scientific Reports3 citations Open access
Semantic Scholar
P109 Clinical development of a novel strategy to mitigate biologic immunogenicity: monthly dosing of a pegylated uricase with SVP-R enables sustained reduction of serum uric acid (SUA) levels by mitigating formation of anti-drug antibodies (ADAS)
E. Sands, Alan J. Kivitz, W. de Haan, Lloyd P. M. Johnston +1 more
20183 citations Open access
Semantic Scholar
FRI0234 Sel-212: selective mitigation of anti-drug antibodies against pegsiticase to control serum uric acid in hyperuricemic subjects
E. Sands, Alan J. Kivitz, Lloyd P. M. Johnston, W. de Haan +1 more
2018FRIDAY, 15 JUNE 20182 citations Open access
Semantic Scholar
Inhaled Cationic Salts Inhibit Infection Of Multiple Viral Pathogens And Prevent Influenza Infection In Vivo
D. Hava, A. Prasse, N. Jewell, Tim Brogan +8 more
2011Asian Test Symposium2 citations
Semantic Scholar
Inhaled Cationic Airway Lining Modulator (iCALM) Therapy, A Novel Aerosol Treatment For Respiratory Infections Reduces Clinical Symptoms And Transmission Of Influenza A Infection.
D. Hava, L. Griel, W. de Haan, C. Hubeau +5 more
2010Asian Test Symposium2 citations
Semantic Scholar

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