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Adam R. Frymoyer · SciRah

Researcher profile · Semantic Scholar

Adam R. Frymoyer

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Adam R. Frymoyer — researcher profile on SciRah

h-index: 30
Works: 85
Citations: 2,954

Most-cited papers

Drug Absorption Interactions Between Oral Targeted Anticancer Agents and PPIs: Is pH‐Dependent Solubility the Achilles Heel of Targeted Therapy?
N. Budha, Adam R. Frymoyer, Gillian S. Smelick, Jin Y. Jin +5 more
2012Clinical pharmacology and therapy333 citations
Semantic Scholar
4-Methylumbelliferone Treatment and Hyaluronan Inhibition as a Therapeutic Strategy in Inflammation, Autoimmunity, and Cancer
N. Nagy, Hedwich F. Kuipers, Adam R. Frymoyer, Heather D. Ishak +3 more
2015Frontiers in Immunology263 citations Open access
Semantic Scholar
Prevalence of acid-reducing agents (ARA) in cancer populations and ARA drug-drug interaction potential for molecular targeted agents in clinical development.
G. Smelick, T. Heffron, L. Chu, Brian J. Dean +9 more
2013Molecular Pharmaceutics185 citations
Semantic Scholar
Current Recommended Dosing of Vancomycin for Children with Invasive Methicillin-Resistant Staphylococcus aureus Infections is Inadequate
Adam R. Frymoyer, A. Hersh, L. Benet, B. Guglielmo
2009The Pediatric Infectious Disease Journal148 citations Open access
Semantic Scholar
Desired Vancomycin Trough Serum Concentration for Treating Invasive Methicillin-resistant Staphylococcal Infections
Adam R. Frymoyer, B. Guglielmo, A. Hersh
2013The Pediatric Infectious Disease Journal140 citations
Semantic Scholar
Association between Vancomycin Trough Concentration and Area under the Concentration-Time Curve in Neonates
Adam R. Frymoyer, A. Hersh, Mohammed H. El-Komy, Shabnam Gaskari +3 more
2014Antimicrobial Agents and Chemotherapy134 citations Open access
Semantic Scholar
Model‐Informed Precision Dosing at the Bedside: Scientific Challenges and Opportunities
R. Keizer, R. ter Heine, Adam R. Frymoyer, L. Lesko +2 more
2018CPT: Pharmacometrics & Systems Pharmacology131 citations Open access
Semantic Scholar
Model-Informed Precision Dosing of Vancomycin in Hospitalized Children: Implementation and Adoption at an Academic Children’s Hospital
Adam R. Frymoyer, H. Schwenk, Yvonne Zorn, L. Bio +6 more
2020Frontiers in Pharmacology65 citations Open access
Semantic Scholar
Clinical Monitoring of Well-Appearing Infants Born to Mothers With Chorioamnionitis
N. Joshi, Arun Gupta, Jessica M. Allan, R. S. Cohen +5 more
2018Pediatrics60 citations Open access
Semantic Scholar
Gentamicin Pharmacokinetics and Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia
Adam R. Frymoyer, Lina Meng, S. Bonifacio, D. Verotta +1 more
2013Pharmacotherapy59 citations Open access
Semantic Scholar
Predictive Performance of a Vancomycin Population Pharmacokinetic Model in Neonates
C. Stockmann, A. Hersh, J. Roberts, Jiraganya Bhongsatiern +4 more
2015Infectious Disease and Therapy57 citations Open access
Semantic Scholar
Individualized Empiric Vancomycin Dosing in Neonates Using a Model-Based Approach.
Adam R. Frymoyer, C. Stockmann, A. Hersh, Srijib Goswami +1 more
2019Journal of the Pediatric Infectious Diseases Society53 citations Open access
Semantic Scholar
Prediction of Vancomycin Pharmacodynamics in Children With Invasive Methicillin-Resistant Staphylococcus aureus Infections: A Monte Carlo Simulation
Adam R. Frymoyer, A. Hersh, Zlatan Coralic, L. Benet +1 more
2010Clinical Therapeutics52 citations Open access
Semantic Scholar
Decreased Morphine Clearance in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia
Adam R. Frymoyer, Sonia L. Bonifacio, David R. Drover, Felice Su +2 more
2016Journal of clinical pharmacology50 citations Open access
Semantic Scholar
Impact of Hospital-Wide Change in Empiric Pediatric Vancomycin Dosing and Associated Therapeutic Concentrations
Adam R. Frymoyer, B. Guglielmo, Stephen D. Wilson, Sarah B. Scarpace +2 more
2011Pharmacotherapy48 citations Open access
Semantic Scholar
The pharmacokinetics and dosing of oral 4‐methylumbelliferone for inhibition of hyaluronan synthesis in mice
Hedwich F. Kuipers, N. Nagy, S. Ruppert, V. Sunkari +9 more
2016Clinical and Experimental Immunology46 citations Open access
Semantic Scholar
4-Methylumbelliferyl glucuronide contributes to hyaluronan synthesis inhibition
N. Nagy, Irina Gurevich, Hedwich F. Kuipers, S. Ruppert +10 more
2019Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Renal Saturation and Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Undergoing Therapeutic Hypothermia
V. Chock, Adam R. Frymoyer, C. Yeh, K. P. Van Meurs
2018Jornal de Pediatria44 citations
Semantic Scholar
Nevirapine (NVP) Pharmacokinetics (PK) and Risk of Rash and Hepatitis among HIV-Infected Sub-Saharan African Women
Betty J. Dong, Yu Zheng, M. Hughes, Adam R. Frymoyer +6 more
2012AIDS (London)44 citations Open access
Semantic Scholar
Infliximab Dosing Strategies and Predicted Trough Exposure in Children with Crohn’s Disease
Adam R. Frymoyer, T. Piester, K. Park
2016Journal of Pediatric Gastroenterology and Nutrition - JPGN42 citations Open access
Semantic Scholar
Delayed distribution of active vasodilation and altered vascular conductance in aged skin.
J. Pierzga, Adam R. Frymoyer, W. Kenney
2003Journal of applied physiology42 citations
Semantic Scholar
Incidence of Neonatal Hypothermia in the Newborn Nursery and Associated Factors
Rebecca Dang, Anisha I. Patel, Ying-Jie Weng, A. Schroeder +3 more
2023JAMA Network Open39 citations Open access
Semantic Scholar
Management of Chorioamnionitis-Exposed Infants in the Newborn Nursery Using a Clinical Examination-Based Approach.
N. Joshi, Arun Gupta, Jessica M. Allan, R. S. Cohen +4 more
2019Hospital Pediatrics39 citations
Semantic Scholar
Placebo-controlled comparison of a morphine/dextromethorphan combination with morphine on experimental pain and hyperalgesia in healthy volunteers.
Adam R. Frymoyer, M. Rowbotham, K. Petersen
2007Journal of Pain39 citations Open access
Semantic Scholar
Population pharmacokinetics of unbound mycophenolic acid in adult allogeneic haematopoietic cell transplantation: effect of pharmacogenetic factors
Adam R. Frymoyer, D. Verotta, P. Jacobson, J. Long-Boyle
2013British Journal of Clinical Pharmacology35 citations Open access
Semantic Scholar
Sustainability of a Clinical Examination-Based Approach for Ascertainment of Early Onset Sepsis in Late Preterm and Term Neonates.
Adam R. Frymoyer, N. Joshi, Jessica M. Allan, R. S. Cohen +4 more
2020Jornal de Pediatria34 citations
Semantic Scholar
The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria
Marc R. Yago, Adam R. Frymoyer, L. Benet, G. Smelick +8 more
2014AAPS Journal34 citations Open access
Semantic Scholar
Oral hymecromone decreases hyaluronan in human study participants
J. Rosser, N. Nagy, Riya Goel, G. Kaber +13 more
2022Journal of Clinical Investigation30 citations Open access
Semantic Scholar
Management of comfort and sedation in neonates with neonatal encephalopathy treated with therapeutic hypothermia
C. McPherson, Adam R. Frymoyer, C. Ortinau, S. Miller +1 more
2021Seminars in Fetal & Neonatal Medicine30 citations Open access
Semantic Scholar
Urine Biomarkers for the Assessment of Acute Kidney Injury in Neonates with Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia.
J. Rumpel, Beverly J. Spray, V. Chock, Megan J. Kirkley +7 more
2021Jornal de Pediatria30 citations
Semantic Scholar
Morphine and fentanyl exposure during therapeutic hypothermia does not impair neurodevelopment
J. K. Gundersen, E. Chakkarapani, S. Jary, D. Menassa +4 more
2021EClinicalMedicine29 citations Open access
Semantic Scholar
High-Dose Erythropoietin Population Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia
Adam R. Frymoyer, Sandra E. Juul, A. Massaro, T. Bammler +1 more
2017Pediatric Research28 citations Open access
Semantic Scholar
Effect of Single-dose Rifampin on the Pharmacokinetics of Warfarin in Healthy Volunteers
Adam R. Frymoyer, S. Shugarts, M. Browne, A. H. Wu +2 more
2010Clinical pharmacology and therapy28 citations Open access
Semantic Scholar
Predictive Performance of a Gentamicin Population Pharmacokinetic Model in Neonates Receiving Full-Body Hypothermia
M. Sampson, Adam R. Frymoyer, B. Rattray, C. Cotten +4 more
2014Therapeutic Drug Monitoring27 citations Open access
Semantic Scholar
Serial clinical observation for management of newborns at risk of early-onset sepsis.
A. Berardi, Luca Bedetti, C. Spada, L. Lucaccioni +1 more
2019Current opinion in pediatrics26 citations Open access
Semantic Scholar
Dovitinib and erlotinib in patients with metastatic non-small cell lung cancer: A drug–drug interaction
M. Das, S. Padda, Adam R. Frymoyer, L. Zhou +3 more
2015Lung Cancer26 citations Open access
Semantic Scholar
Epidemiology and trends in neonatal early onset sepsis in California, 2010–2017
N. Joshi, Karen Huynh, T. Lu, Henry C. Lee +1 more
2022Journal of Perinatology25 citations
Semantic Scholar
Application of Population Pharmacokinetic Modeling for Individualized Infliximab Dosing Strategies in Crohn's Disease
Adam R. Frymoyer, D. Hoekman, T. Piester, T. de Meij +4 more
2017Journal of Pediatric Gastroenterology and Nutrition - JPGN25 citations Open access
Semantic Scholar
Aminophylline for Renal Protection in Neonatal Hypoxic Ischemic Encephalopathy in the Era of Therapeutic Hypothermia
V. Chock, Seo-Ho Cho, Adam R. Frymoyer
2020Pediatric Research24 citations Open access
Semantic Scholar
Antimicrobial Disposition During Pediatric Continuous Renal Replacement Therapy Using an Ex Vivo Model.
P. Purohit, M. El Komy, Adam R. Frymoyer, S. Sutherland +3 more
2019Critical Care Medicine23 citations
Semantic Scholar
Every 36-hour Gentamicin Dosing in Neonates with Hypoxic Ischemic Encephalopathy Receiving Hypothermia
Adam R. Frymoyer, Shi-Hsin Lee, S. Bonifacio, Lina Meng +4 more
2013Journal of Perinatology23 citations Open access
Semantic Scholar
Evaluation of Neonatal and Paediatric Vancomycin Pharmacokinetic Models and the Impact of Maturation and Serum Creatinine Covariates in a Large Multicentre Data Set
Jasmine H. Hughes, Dominic M. H. Tong, Jonathan D. Faldasz, Adam R. Frymoyer +1 more
2022Clinical Pharmacokinetics22 citations Open access
Semantic Scholar
Serum Creatinine Patterns in Neonates Treated with Therapeutic Hypothermia for Neonatal Encephalopathy
Elif Keleş, P. Wintermark, F. Groenendaal, Noor Borloo +12 more
2022Neonatology21 citations Open access
Semantic Scholar
The Term Newborn: Early-Onset Sepsis.
K. Puopolo, Sagori Mukhopadhay, Adam R. Frymoyer, W. Benitz
2021Clinics of Perinatology21 citations
Semantic Scholar
Gastric Re-acidification with Betaine HCl in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria
Marc R. Yago, Adam R. Frymoyer, G. Smelick, L. Frassetto +4 more
2013Molecular Pharmaceutics21 citations Open access
Semantic Scholar
An Evaluation of Vancomycin Area Under the Curve Estimation Methods for Children Treated for Acute Pulmonary Exacerbations of Cystic Fibrosis Due to Methicillin‐Resistant Staphylococcus aureus
C. Stockmann, Jared K. Olson, Jahidur Rashid, Lisa Lubsch +8 more
2018Journal of clinical pharmacology19 citations Open access
Semantic Scholar
Pharmacokinetics, Pharmacodynamics, and Safety of Lisinopril in Pediatric Kidney Transplant Patients: Implications for Starting Dose Selection
H. Trachtman, Adam R. Frymoyer, Andrew Lewandowski, L. Greenbaum +8 more
2015Clinical pharmacology and therapy18 citations Open access
Semantic Scholar
Pharmacokinetics of Morphine and Its Metabolites in Infants and Young Children After Congenital Heart Surgery
M. El Komy, D. Drover, K. Glotzbach, J. Galinkin +3 more
2015AAPS Journal17 citations Open access
Semantic Scholar
Repurposing Drugs for Acute Myeloid Leukemia: A Worthy Cause or a Futile Pursuit?
Anna V Wojcicki, Meena Kadapakkam, Adam R. Frymoyer, N. Lacayo +2 more
2020Cancers16 citations Open access
Semantic Scholar
Standardized Evaluation of Cord Gases in Neonates at Risk for Hypoxic Ischemic Encephalopathy.
Elizabeth Blecharczyk, L. Lee, Krista L. Birnie, Arpita Gupta +4 more
2021Hospital Pediatrics15 citations
Semantic Scholar

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