Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Jin Y. Jin · SciRah

Researcher profile · Semantic Scholar

Jin Y. Jin

Share profile

Jin Y. Jin — researcher profile on SciRah

h-index: 26
Works: 87
Citations: 2,598

Most-cited papers

Drug Absorption Interactions Between Oral Targeted Anticancer Agents and PPIs: Is pH‐Dependent Solubility the Achilles Heel of Targeted Therapy?
N. Budha, Adam R. Frymoyer, Gillian S. Smelick, Jin Y. Jin +5 more
2012Clinical pharmacology and therapy333 citations
Semantic Scholar
Clinical Pharmacokinetics and Pharmacodynamics of Atezolizumab in Metastatic Urothelial Carcinoma
M. Stroh, H. Winter, M. Marchand, L. Claret +9 more
2017Clinical pharmacology and therapy146 citations
Semantic Scholar
Progression-free survival as a surrogate endpoint for overall survival in glioblastoma: a literature-based meta-analysis from 91 trials
Kelong Han, Melanie Ren, W. Wick, L. Abrey +3 more
2013Neuro-Oncology135 citations Open access
Semantic Scholar
Pharmacokinetics of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Locally Advanced or Metastatic Solid Tumors: the Role of Alpha-1-Acid Glycoprotein Binding
R. Graham, B. Lum, S. Cheeti, Jin Y. Jin +6 more
2011Clinical Cancer Research118 citations Open access
Semantic Scholar
Application of IVIVE and PBPK modeling in prospective prediction of clinical pharmacokinetics: strategy and approach during the drug discovery phase with four case studies
Yuan Chen, Jin Y. Jin, S. Mukadam, V. Malhi +1 more
2012Biopharmaceutics & drug disposition108 citations
Semantic Scholar
A physiologically based pharmacokinetic (PBPK) approach to evaluate pharmacokinetics in patients with cancer
S. Cheeti, N. Budha, S. Rajan, M. Dresser +1 more
2013Biopharmaceutics & drug disposition99 citations
Semantic Scholar
Population pharmacokinetics of trastuzumab emtansine (T-DM1), a HER2-targeted antibody–drug conjugate, in patients with HER2-positive metastatic breast cancer: clinical implications of the effect of covariates
D. Lu, S. Girish, Yu-Ying Gao, Bei Wang +7 more
2014Cancer Chemotherapy and Pharmacology95 citations Open access
Semantic Scholar
Pharmacokinetic Dose-Scheduling Study of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Locally Advanced or Metastatic Solid Tumors
P. LoRusso, A. Jimeno, G. Dy, A. Adjei +8 more
2011Clinical Cancer Research90 citations Open access
Semantic Scholar
Alternative dosing regimens for atezolizumab: an example of model-informed drug development in the postmarketing setting
K. Morrissey, M. Marchand, H. Patel, Rong Zhang +7 more
2019Cancer Chemotherapy and Pharmacology81 citations Open access
Semantic Scholar
Progress and Opportunities to Advance Clinical Cancer Therapeutics Using Tumor Dynamic Models
R. Bruno, D. Bottino, D. de Alwis, A. Fojo +6 more
2019Clinical Cancer Research73 citations Open access
Semantic Scholar
Population pharmacokinetics of bevacizumab in cancer patients with external validation
Kelong Han, T. Peyret, M. Marchand, A. Quartino +4 more
2016Cancer Chemotherapy and Pharmacology71 citations Open access
Semantic Scholar
A Model of Overall Survival Predicts Treatment Outcomes with Atezolizumab versus Chemotherapy in Non–Small Cell Lung Cancer Based on Early Tumor Kinetics
L. Claret, Jin Y. Jin, C. Ferté, H. Winter +10 more
2018Clinical Cancer Research64 citations Open access
Semantic Scholar
Population pharmacokinetic and exposure–response analysis for trastuzumab administered using a subcutaneous “manual syringe” injection or intravenously in women with HER2-positive early breast cancer
A. Quartino, C. Hillenbach, Jing Li, Han-Bin Li +6 more
2015Cancer Chemotherapy and Pharmacology64 citations Open access
Semantic Scholar
Population pharmacokinetic and covariate analysis of pertuzumab, a HER2-targeted monoclonal antibody, and evaluation of a fixed, non-weight-based dose in patients with a variety of solid tumors
Amit Garg, A. Quartino, Jing Li, Jin Y. Jin +7 more
2014Cancer Chemotherapy and Pharmacology60 citations
Semantic Scholar
Lower Exposure and Faster Clearance of Bevacizumab in Gastric Cancer and the Impact of Patient Variables: Analysis of Individual Data from AVAGAST Phase III Trial
Kelong Han, Jin Y. Jin, M. Maia, John B. Lowe +2 more
2014AAPS Journal45 citations Open access
Semantic Scholar
Physiologically Based Pharmacokinetic Modeling as a Tool to Predict Drug Interactions for Antibody-Drug Conjugates
Yuan Chen, D. Samineni, S. Mukadam, H. Wong +6 more
2014Clinical Pharmacokinetics45 citations
Semantic Scholar
Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer’s disease
K. Yoshida, A. Moein, T. Bittner, S. Ostrowitzki +4 more
2020Alzheimer's Research & Therapy40 citations Open access
Semantic Scholar
Bevacizumab dosing strategy in paediatric cancer patients based on population pharmacokinetic analysis with external validation
Kelong Han, T. Peyret, A. Quartino, Nathalie H. Gosselin +9 more
2015British Journal of Clinical Pharmacology40 citations Open access
Semantic Scholar
Population pharmacokinetics, exposure-safety, and immunogenicity of atezolizumab in pediatric and young adult patients with cancer
C. Shemesh, P. Chanu, K. Jamsen, R. Wada +9 more
2019Journal of Immunotherapy for Cancer38 citations Open access
Semantic Scholar
Integrated Two‐Analyte Population Pharmacokinetic Model of Polatuzumab Vedotin in Patients With Non‐Hodgkin Lymphoma
D. Lu, T. Lu, L. Gibiansky, Xiao-Bin Li +10 more
2019CPT: Pharmacometrics & Systems Pharmacology37 citations Open access
Semantic Scholar
Evaluation of Cytochrome P450 3A4-Mediated Drug–Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation
N. Budha, Tao Ji, L. Musib, S. Eppler +3 more
2016Clinical Pharmacokinetics36 citations
Semantic Scholar
The Use of Betaine HCl to Enhance Dasatinib Absorption in Healthy Volunteers with Rabeprazole-Induced Hypochlorhydria
Marc R. Yago, Adam R. Frymoyer, L. Benet, G. Smelick +8 more
2014AAPS Journal34 citations Open access
Semantic Scholar
Population pharmacokinetic and covariate analyses of intravenous trastuzumab (Herceptin®), a HER2-targeted monoclonal antibody, in patients with a variety of solid tumors
A. Quartino, Han-Bin Li, Whitney P. Kirschbrown, R. Mangat +4 more
2018Cancer Chemotherapy and Pharmacology33 citations Open access
Semantic Scholar
Time-dependent population PK models of single-agent atezolizumab in patients with cancer
M. Marchand, Rong Zhang, P. Chan, V. Quarmby +5 more
2021Cancer Chemotherapy and Pharmacology29 citations
Semantic Scholar
A Mechanistic Pharmacokinetic/Pharmacodynamic Model of Factor D Inhibition in Cynomolgus Monkeys by Lampalizumab for the Treatment of Geographic Atrophy
Kha N. Le, L. Gibiansky, J. Good, Teresa Davancaze +6 more
2015Journal of Pharmacology and Experimental Therapeutics29 citations Open access
Semantic Scholar
Exposure–response analyses of trastuzumab emtansine in patients with HER2-positive advanced breast cancer previously treated with trastuzumab and a taxane
Chunze Li, Bei Wang, Shang-Chiung Chen, R. Wada +12 more
2017Cancer Chemotherapy and Pharmacology26 citations
Semantic Scholar
Development of a Physiologically Based Pharmacokinetic Model for Itraconazole Pharmacokinetics and Drug–Drug Interaction Prediction
Yuan Chen, Fang Ma, T. Lu, N. Budha +5 more
2016Clinical Pharmacokinetics26 citations
Semantic Scholar
Physiologically Based Pharmacokinetic Model‐Informed Drug Development for Polatuzumab Vedotin: Label for Drug‐Drug Interactions Without Dedicated Clinical Trials
D. Samineni, Hao Ding, Fang Ma, Rong Shi +8 more
2020Journal of clinical pharmacology25 citations
Semantic Scholar
Application of Machine Learning for Tumor Growth Inhibition – Overall Survival Modeling Platform
P. Chan, Xiao-Fei Zhou, Nina Wang, Qi Liu +2 more
2020CPT: Pharmacometrics & Systems Pharmacology24 citations Open access
Semantic Scholar
Population pharmacokinetics and dosing implications for cobimetinib in patients with solid tumors
Kelong Han, Jin Y. Jin, M. Marchand, S. Eppler +8 more
2015Cancer Chemotherapy and Pharmacology24 citations
Semantic Scholar
Semi-mechanistic Multiple-Analyte Pharmacokinetic Model for an Antibody-Drug-Conjugate in Cynomolgus Monkeys
D. Lu, Jin Y. Jin, S. Girish, P. Agarwal +8 more
2014Pharmaceutical Research24 citations Open access
Semantic Scholar
Pharmacokinetic and exposure–response analyses of pertuzumab in combination with trastuzumab and docetaxel during neoadjuvant treatment of HER2+ early breast cancer
A. Quartino, Han-Bin Li, Jin Y. Jin, D. Wada +6 more
2017Cancer Chemotherapy and Pharmacology22 citations Open access
Semantic Scholar
Exposure-safety and exposure-efficacy analyses of polatuzumab vedotin in patients with relapsed or refractory diffuse large B-cell lymphoma
T. Lu, L. Gibiansky, Xiao-Bin Li, Chunze Li +8 more
2020Leukemia and Lymphoma21 citations Open access
Semantic Scholar
Short‐Term Efficacy Reliably Predicts Long‐Term Clinical Benefit in Rheumatoid Arthritis Clinical Trials as Demonstrated by Model‐Based Meta‐Analysis
Yehong Wang, R. Zhu, Jim J. Xiao, John C. Davis +3 more
2015Journal of clinical pharmacology20 citations Open access
Semantic Scholar
Population pharmacokinetics and exposure–response of trastuzumab emtansine in advanced breast cancer previously treated with ≥2 HER2‐targeted regimens
Shang-Chiung Chen, A. Quartino, D. Polhamus, M. Riggs +9 more
2017British Journal of Clinical Pharmacology19 citations Open access
Semantic Scholar
Semi‐Mechanism‐Based Population Pharmacokinetic Modeling of the Hedgehog Pathway Inhibitor Vismodegib
Tong Lu, B. Wang, Y. Gao, M. Dresser +2 more
2015CPT: Pharmacometrics & Systems Pharmacology19 citations Open access
Semantic Scholar
Impact of Physiologically Based Pharmacokinetics, Population Pharmacokinetics and Pharmacokinetics/Pharmacodynamics in the Development of Antibody‐Drug Conjugates
Chunze Li, Shang-Chiung Chen, Yuan Chen, S. Girish +5 more
2020Journal of clinical pharmacology18 citations Open access
Semantic Scholar
Physiologically‐Based Pharmacokinetic Model‐Informed Drug Development for Fenebrutinib: Understanding Complex Drug‐Drug Interactions
Yuan Chen, Fang Ma, N. S. Jones, K. Yoshida +5 more
2020CPT: Pharmacometrics & Systems Pharmacology18 citations Open access
Semantic Scholar
Exposure–Response‐Based Product Profile–Driven Clinical Utility Index for Ipatasertib Dose Selection in Prostate Cancer
Rui Zhu, B. Poland, R. Wada, Qi Liu +7 more
2019CPT: Pharmacometrics & Systems Pharmacology18 citations Open access
Semantic Scholar
Impact of food and the proton pump inhibitor rabeprazole on the pharmacokinetics of GDC-0941 in healthy volunteers: bench to bedside investigation of pH-dependent solubility.
J. Ware, Gena Dalziel, Jin Y. Jin, Jackson D. Pellett +9 more
2013Molecular Pharmaceutics18 citations
Semantic Scholar
Model-based clinical pharmacology profiling and exposure-response relationships of the efficacy and biomarker of lebrikizumab in patients with moderate-to-severe asthma.
Rui Zhu, Yanan Zheng, N. Dirks, S. Vadhavkar +6 more
2017Pulmonary Pharmacology & Therapeutics17 citations Open access
Semantic Scholar
Ethnic sensitivity assessment of the antibody–drug conjugate trastuzumab emtansine (T-DM1) in patients with HER2-positive locally advanced or metastatic breast cancer
Chunze Li, Bei Wang, D. Lu, Jin Y. Jin +8 more
2016Cancer Chemotherapy and Pharmacology17 citations
Semantic Scholar
Pharmacokinetics of polatuzumab vedotin in combination with R/G-CHP in patients with B-cell non-Hodgkin lymphoma
C. Shemesh, P. Agarwal, T. Lu, Calvin Lee +7 more
2020Cancer Chemotherapy and Pharmacology16 citations Open access
Semantic Scholar
Time‐to‐Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine‐Citrulline‐Monomethylauristatin E Antibody–Drug Conjugates
M. Kågedal, D. Samineni, W. Gillespie, D. Lu +4 more
2019CPT: Pharmacometrics & Systems Pharmacology16 citations Open access
Semantic Scholar
Population pharmacokinetics of trastuzumab emtansine in previously treated patients with HER2-positive advanced gastric cancer (AGC)
Shang-Chiung Chen, M. Kågedal, Yu-Ying Gao, Bei Wang +4 more
2017Cancer Chemotherapy and Pharmacology16 citations
Semantic Scholar
Analysis of Longitudinal‐Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models
T. Lu, Yujie Yang, Jin Y. Jin, M. Kågedal
2019CPT: Pharmacometrics & Systems Pharmacology15 citations Open access
Semantic Scholar
A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory
E. Schindler, L. Friberg, Bertram L. Lum, Bei Wang +5 more
2018Pharmaceutical Research15 citations Open access
Semantic Scholar
A Phase I Pharmacokinetic Study of Trastuzumab Emtansine (T-DM1) in Patients with Human Epidermal Growth Factor Receptor 2-Positive Metastatic Breast Cancer and Normal or Reduced Hepatic Function
Chunze Li, P. Agarwal, E. Gibiansky, Jin Y. Jin +8 more
2017Clinical Pharmacokinetics15 citations
Semantic Scholar
Early Decision Making in a Randomized Phase II Trial of Atezolizumab in Biliary Tract Cancer Using a Tumor Growth Inhibition‐Survival Modeling Framework
C. Shemesh, P. Chan, M. Marchand, Antonio Gonçalves +6 more
2023Clinical pharmacology and therapy13 citations
Semantic Scholar
Application of a Two-Analyte Integrated Population Pharmacokinetic Model to Evaluate the Impact of Intrinsic and Extrinsic Factors on the Pharmacokinetics of Polatuzumab Vedotin in Patients with Non-Hodgkin Lymphoma
D. Lu, T. Lu, Rong Shi, L. Gibiansky +10 more
2020Pharmaceutical Research13 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

S. Girish×21
Invite
S. Girish — researcher profile on SciRah
Chunze Li×16
Invite
Chunze Li — researcher profile on SciRah
D. Lu×12
Invite
D. Lu — researcher profile on SciRah
A. Quartino×10
Invite
A. Quartino — researcher profile on SciRah

×8

Invite

R. Bruno — researcher profile on SciRah

Invite

N. Budha — researcher profile on SciRah

Invite

M. Dresser — researcher profile on SciRah

Invite

Yuan Chen — researcher profile on SciRah

Invite

T. Lu — researcher profile on SciRah

Invite

M. Marchand — researcher profile on SciRah

Invite

P. Agarwal — researcher profile on SciRah

Invite

Kelong Han — researcher profile on SciRah