E. Chakkarapani

Most-cited papers

1. Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

   Obbina Ali Fatima Mustafa Sadia Hakam Alfie Nabeel Ashraf Abani Abbas Abbas Abbas Abbasi Abbass Abbott Abdal, O. Abani, A. Abbas, F. Abbas +496 more

   2021The Lancet1,685 citations Open access

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2. Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

   Eugenia Mustafa Sadia Alfie Ashraf Sherif Mohamed Basir Al Abaleke Abbas Abbasi Abbott Abdelaziz Abdelbadiee , E. Abaleke, M. Abbas, Sadia Abbasi +496 more

   2021The Lancet289 citations Open access

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3. Xenon and Hypothermia Combine Additively, Offering Long-Term Functional and Histopathologic Neuroprotection After Neonatal Hypoxia/Ischemia

   Catherine E. Hobbs, M. Thoresen, A. Tucker, K. Aquilina +2 more

   2008Stroke249 citations Open access

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4. Cooling Combined with Immediate or Delayed Xenon Inhalation Provides Equivalent Long-Term Neuroprotection after Neonatal Hypoxia—Ischemia

   M. Thoresen, Catherine E. Hobbs, T. Wood, E. Chakkarapani +1 more

   2009Journal of Cerebral Blood Flow and Metabolism169 citations Open access

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5. Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs

   E. Chakkarapani, J. Dingley, Xun Liu, Nicholas Hoque +3 more

   2010Annals of Neurology151 citations

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6. Association of Prenatal Diagnosis of Critical Congenital Heart Disease With Postnatal Brain Development and the Risk of Brain Injury

   S. Peyvandi, Veronica de Santiago, E. Chakkarapani, V. Chau +6 more

   2016JAMA pediatrics148 citations Open access

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7. Xenon Ventilation During Therapeutic Hypothermia in Neonatal Encephalopathy: A Feasibility Study

   J. Dingley, J. Tooley, Xun Liu, Emma Scull-Brown +4 more

   2014Pediatrics109 citations Open access

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8. Higher dose corticosteroids in patients admitted to hospital with COVID-19 who are hypoxic but not requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial

   O. A. F. J. K. M. S. H. A. Abani Abbas Abbas Abbas Abbas Abbas Abbasi Abbass, O. Abani, A. Abbas, F. Abbas +496 more

   2023The Lancet103 citations Open access

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9. School-age outcomes of children without cerebral palsy cooled for neonatal hypoxic–ischaemic encephalopathy in 2008–2010

   R. Lee-kelland, S. Jary, J. Tonks, F. Cowan +2 more

   2019Archives of Disease in Childhood: Fetal and Neonatal Edition92 citations Open access

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10. Lactate dehydrogenase predicts hypoxic ischaemic encephalopathy in newborn infants: a preliminary study

    Mathias Karlsson, E. Wiberg-Itzel, E. Chakkarapani, M. Blennow +2 more

    2010Acta paediatrica84 citations

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11. Serum Gentamicin Concentrations in Encephalopathic Infants are Not Affected by Therapeutic Hypothermia

    Xun Liu, M. Borooah, Janet Stone, E. Chakkarapani +1 more

    2009Pediatrics66 citations

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12. Delayed Hypothermia as Selective Head Cooling or Whole Body Cooling Does Not Protect Brain or Body in Newborn Pig Subjected to Hypoxia-Ischemia

    Mathias Karlsson, J. Tooley, S. Šatas, Catherine E. Hobbs +4 more

    2008Pediatric Research66 citations

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13. Glutamate Transport and Preterm Brain Injury

    Silvia Pregnolato, E. Chakkarapani, A. Isles, Karen Luyt

    2019Frontiers in Physiology63 citations Open access

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14. A Comparison of Cooling Methods Used in Therapeutic Hypothermia for Perinatal Asphyxia

    Nicholas Hoque, E. Chakkarapani, Xun Liu, M. Thoresen

    2010Pediatrics62 citations

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15. A Closed-Circuit Neonatal Xenon Delivery System: A Technical and Practical Neuroprotection Feasibility Study in Newborn Pigs

    E. Chakkarapani, M. Thoresen, Catherine E. Hobbs, K. Aquilina +2 more

    2009Anesthesia and Analgesia55 citations Open access

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16. MRI combined with early clinical variables are excellent outcome predictors for newborn infants undergoing therapeutic hypothermia after perinatal asphyxia

    M. Thoresen, S. Jary, L. Walløe, Mathias Karlsson +3 more

    2021EClinicalMedicine53 citations Open access

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17. Therapeutic hypothermia delays the C-reactive protein response and suppresses white blood cell and platelet count in infants with neonatal encephalopathy

    E. Chakkarapani, Jonathan Davis, M. Thoresen

    2014Archives of Disease in Childhood: Fetal and Neonatal Edition53 citations

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18. Development of Amplitude-Integrated Electroencephalography and Interburst Interval in the Rat

    A. Tucker, K. Aquilina, E. Chakkarapani, Catherine E. Hobbs +1 more

    2009Pediatric Research53 citations

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19. Reliability of Early Magnetic Resonance Imaging (MRI) and Necessity of Repeating MRI in Noncooled and Cooled Infants With Neonatal Encephalopathy

    E. Chakkarapani, K. Poskitt, S. Miller, J. Zwicker +5 more

    2016Journal of Child Neurology35 citations Open access

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20. Survey of nutritional practices during therapeutic hypothermia for hypoxic-ischaemic encephalopathy

    Beth Hazeldine, B. Thyagarajan, M. Grant, E. Chakkarapani

    2017BMJ Paediatrics Open32 citations Open access

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21. Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia.

    Xun Liu, E. Chakkarapani, Janet Stone, M. Thoresen

    2013Resuscitation31 citations

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22. Xenon offers stable haemodynamics independent of induced hypothermia after hypoxia–ischaemia in newborn pigs

    E. Chakkarapani, M. Thoresen, Xun Liu, L. Walløe +1 more

    2012Intensive Care Medicine30 citations Open access

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23. Morphine and fentanyl exposure during therapeutic hypothermia does not impair neurodevelopment

    J. K. Gundersen, E. Chakkarapani, S. Jary, D. Menassa +4 more

    2021EClinicalMedicine29 citations Open access

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24. Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy: a case-control study

    J. Tonks, Grace Cloke, R. Lee-kelland, S. Jary +3 more

    2019Brain Injury29 citations Open access

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25. Disrupted brain connectivity in children treated with therapeutic hypothermia for neonatal encephalopathy

    A. P. C. Spencer, Jonathan C. W. Brooks, N. Masuda, H. Byrne +7 more

    2021NeuroImage: Clinical26 citations Open access

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26. Differential Tiam1/Rac1 Activation in Hippocampal and Cortical Neurons Mediates Differential Spine Shrinkage in Response to Oxygen/Glucose Deprivation

    Elena Blanco-Suárez, María Fiuza, Xun Liu, E. Chakkarapani +1 more

    2014Journal of Cerebral Blood Flow and Metabolism24 citations Open access

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27. Brain volumes and functional outcomes in children without cerebral palsy after therapeutic hypothermia for neonatal hypoxic‐ischaemic encephalopathy

    A. P. C. Spencer, R. Lee-kelland, Jonathan C. W. Brooks, S. Jary +4 more

    2022Developmental Medicine & Child Neurology23 citations Open access

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28. Multivariate analyses of factors that affect neonatal screening thyroid stimulating hormone

    S. M. Ng, S. C. Wong, F. Paize, E. Chakkarapani +3 more

    2011Journal of Pediatric Endocrinology & Metabolism (JPEM)23 citations

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29. The Feasibility of Using a Portable Xenon Delivery Device to Permit Earlier Xenon Ventilation with Therapeutic Cooling of Neonates During Ambulance Retrieval

    J. Dingley, Xun Liu, Hannah Gill, E. Smit +5 more

    2015Anesthesia and Analgesia22 citations

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30. Neonatal rat model of intraventricular haemorrhage and post‐haemorrhagic ventricular dilatation with long‐term survival into adulthood

    K. Aquilina, E. Chakkarapani, S. Love, M. Thoresen

    2011Neuropathology and Applied Neurobiology22 citations

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31. Physiological responses to cuddling babies with hypoxic–ischaemic encephalopathy during therapeutic hypothermia: an observational study

    D. Odd, Satomi Okano, J. Ingram, P. Blair +4 more

    2021BMJ Paediatrics Open21 citations Open access

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32. Preliminary evaluation of a novel intraparenchymal capacitive intracranial pressure monitor.

    K. Aquilina, M. Thoresen, E. Chakkarapani, I. Pople +2 more

    2011Journal of Neurosurgery19 citations

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33. Early deterioration of cerebrospinal fluid dynamics in a neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation.

    K. Aquilina, E. Chakkarapani, M. Thoresen

    2012Journal of Neurosurgery: Pediatrics18 citations

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34. Communication skills in children aged 6–8 years, without cerebral palsy cooled for neonatal hypoxic-ischemic encephalopathy

    T. J. Robb, J. Tonks, A. P. C. Spencer, S. Jary +4 more

    2022Scientific Reports17 citations Open access

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35. Mammillary body abnormalities and cognitive outcomes in children cooled for neonatal encephalopathy

    A. P. C. Spencer, M. Lequin, L. D. de Vries, Jonathan C. W. Brooks +5 more

    2022Developmental Medicine & Child Neurology17 citations Open access

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36. Challenges in respiratory management during therapeutic hypothermia for neonatal encephalopathy.

    M. Eldib, E. Szakmar, E. Chakkarapani, H. Aly

    2021Seminars in Fetal & Neonatal Medicine17 citations

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37. Fentanyl Induces Cerebellar Internal Granular Cell Layer Apoptosis in Healthy Newborn Pigs

    H. Sabir, J. Dingley, Emma Scull-Brown, E. Chakkarapani +1 more

    2018Frontiers in Neurology17 citations Open access

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38. Effects of Xenon and Hypothermia on Cerebrovascular Pressure Reactivity in Newborn Global Hypoxic—ischemic Pig Model

    E. Chakkarapani, J. Dingley, K. Aquilina, D. Osredkar +2 more

    2013Journal of Cerebral Blood Flow and Metabolism17 citations Open access

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39. ‘Opportunity to bond and a sense of normality’: Parent and staff views of cuddling babies undergoing therapeutic hypothermia in neonatal intensive care: ‘CoolCuddle’

    J. Ingram, L. Beasant, D. Odd, E. Chakkarapani

    2022Health Expectations16 citations Open access

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40. Motor function and white matter connectivity in children cooled for neonatal encephalopathy

    A. P. C. Spencer, Jonathan C. W. Brooks, N. Masuda, H. Byrne +6 more

    2021NeuroImage: Clinical15 citations Open access

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41. Development of the corpus callosum and cognition after neonatal encephalopathy

    H. Byrne, A. P. C. Spencer, G. Geary, S. Jary +4 more

    2022Annals of Clinical and Translational Neurology14 citations Open access

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42. Fifteen-minute consultation: Therapeutic hypothermia for infants with hypoxic ischaemic encephalopathy—translating jargon, prognosis and uncertainty for parents

    Paul Cawley, E. Chakkarapani

    2019Archives of Disease in Childhood - Education and Practice13 citations Open access

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43. Neuronal let-7b-5p acts through the Hippo-YAP pathway in neonatal encephalopathy

    Vennila Ponnusamy, Richard Ip, M. Mohamed, P. Clarke +10 more

    2021Communications Biology12 citations Open access

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44. Antenatal and neonatal exposure to SARS-CoV-2 and children’s development: a systematic review and meta-analysis

    Rebecca Jackson, Kathryn Woodward, M. Ireland, C. Larkin +6 more

    2023Pediatric Research11 citations Open access

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45. Factors associated with MRI success in children cooled for neonatal encephalopathy and controls

    Kathryn Woodward, A. P. C. Spencer, S. Jary, E. Chakkarapani

    2022Pediatric Research10 citations Open access

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46. Use of Hypothermia in the Asphyxiated Infant

    E. Chakkarapani, M. Thoresen

    201010 citations

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47. A Randomized Controlled Trial of the Use of Oral Glucose with or without Gentle Facilitated Tucking of Infants during Neonatal Echocardiography

    P. Lavoie, A. Stritzke, J. Ting, Mohammad Jabr +7 more

    2015PLoS ONE8 citations Open access

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48. Therapeutic hypothermia: surgical infant with neonatal encephalopathy

    E. Chakkarapani, D. Harding, P. Stoddart, R. Garrett-Cox +1 more

    2009Acta paediatrica8 citations

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49. Peak expiratory flow rate in children--a ready reckoner.

    S. Balasubramanian, N. Ravikumar, E. Chakkarapani, S. Shivbalan

    2002Indian Pediatrics7 citations

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50. Closed circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects

    J. Dingley, Satomi Okano, R. Lee-kelland, Emma Scull-Brown +2 more

    2020PLoS ONE6 citations Open access

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