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W. Versées · SciRah

Researcher profile · Semantic Scholar

W. Versées

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W. Versées — researcher profile on SciRah

h-index: 32
Works: 152
Citations: 3,367

Most-cited papers

Obg and Membrane Depolarization Are Part of a Microbial Bet-Hedging Strategy that Leads to Antibiotic Tolerance.
N. Verstraeten, Wouter Knapen, C. Kint, V. Liebens +13 more
2015Molecules and Cells297 citations Open access
Semantic Scholar
The Universally Conserved Prokaryotic GTPases
N. Verstraeten, M. Fauvart, W. Versées, J. Michiels
2011Microbiology and Molecular Reviews192 citations Open access
Semantic Scholar
Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras
Ken Peeters, Frederik Van Leemputte, B. Fischer, B. Bonini +10 more
2017Nature Communications178 citations Open access
Semantic Scholar
A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover
E. Deyaert, Lina Wauters, Giambattista Guaitoli, A. Konijnenberg +13 more
2017Nature Communications156 citations Open access
Semantic Scholar
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
Giambattista Guaitoli, Francesco Raimondi, Bernd K. Gilsbach, Y. Gómez-Llorente +18 more
2016Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
ELP3 controls active zone morphology by acetylating the ELKS family member Bruchpilot.
K. Miśkiewicz, L. Jose, A. Bento-Abreu, M. Fislage +7 more
2011Neuron113 citations Open access
Semantic Scholar
Characterization of two homologous 2′-O-methyltransferases showing different specificities for their tRNA substrates
J. Somme, B. Van Laer, M. Roovers, J. Steyaert +2 more
2014RNA: A publication of the RNA Society77 citations Open access
Semantic Scholar
Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function
B. Fischer, Kevin Lüthy, J. Paesmans, Charlotte De Koninck +6 more
2016Nature Structural &Molecular Biology66 citations Open access
Semantic Scholar
TBC1D24-TLDc-related epilepsy exercise-induced dystonia: rescue by antioxidants in a disease model.
Kevin Lüthy, D. Mei, B. Fischer, M. De Fusco +14 more
2019Brain : a journal of neurology55 citations Open access
Semantic Scholar
Crystal structures of the tRNA:m2G6 methyltransferase Trm14/TrmN from two domains of life
M. Fislage, M. Roovers, I. Tuszyńska, J. Bujnicki +2 more
2012Nucleic Acids Research50 citations Open access
Semantic Scholar
Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF*♦
V. Zorzini, Andrej Mernik, J. Lah, Y. Sterckx +5 more
2016Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Deep mutational scanning of essential bacterial proteins can guide antibiotic development
Liselot Dewachter, A. Brooks, Katherine Noon, C. Cialek +6 more
2022bioRxiv48 citations Open access
Semantic Scholar
EndophilinA-dependent coupling between activity-induced calcium influx and synaptic autophagy is disrupted by a Parkinson-risk mutation
Adekunle T. Bademosi, M. Decet, S. Kuenen, C. Calatayud +16 more
2023Neuron44 citations Open access
Semantic Scholar
Nanobodies as allosteric modulators of Parkinson’s disease–associated LRRK2
R. Singh, Ahmed Soliman, Giambattista Guaitoli, Eliza Störmer +16 more
2021bioRxiv44 citations Open access
Semantic Scholar
Phosphorylation decelerates conformational dynamics in bacterial translation elongation factors
A. Talavera, Jelle Hendrix, W. Versées, D. Jurėnas +13 more
2018Science Advances42 citations Open access
Semantic Scholar
Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis
Maya Berg, L. Kohl, P. Van der Veken, J. Joossens +12 more
2010Antimicrobial Agents and Chemotherapy42 citations Open access
Semantic Scholar
Roco Proteins: GTPases with a Baroque Structure and Mechanism
Lina Wauters, W. Versées, A. Kortholt
2019International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Structural and functional insights into tRNA binding and adenosine N1-methylation by an archaeal Trm10 homologue
B. Van Laer, M. Roovers, Lina Wauters, Joanna M. Kasprzak +7 more
2015Nucleic Acids Research36 citations Open access
Semantic Scholar
Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.
Leah G. Helton, Ahmed Soliman, Felix von Zweydorf, Michalis Kentros +14 more
2021ACS Chemical Biology29 citations Open access
Semantic Scholar
A putative de-N-acetylase of the PIG-L superfamily affects fluoroquinolone tolerance in Pseudomonas aeruginosa.
V. Liebens, Valerie Defraine, Annelies Van der Leyden, Valérie N. De Groote +11 more
2014Pathogens and Disease28 citations Open access
Semantic Scholar
SAXS analysis of the tRNA-modifying enzyme complex MnmE/MnmG reveals a novel interaction mode and GTP-induced oligomerization
M. Fislage, E. Brosens, E. Deyaert, Alessandro Spilotros +5 more
2014Nucleic Acids Research28 citations Open access
Semantic Scholar
Structure and nucleotide-induced conformational dynamics of the Chlorobium tepidum Roco protein.
E. Deyaert, Margaux Leemans, R. Singh, R. Gallardo +4 more
2019Biochemical Journal26 citations Open access
Semantic Scholar
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis
L. Rosado, K. Wahni, Giulia Degiacomi, B. Pedre +16 more
2017Journal of Biological Chemistry24 citations Open access
Semantic Scholar
A Single-Amino-Acid Substitution in Obg Activates a New Programmed Cell Death Pathway in Escherichia coli
Liselot Dewachter, N. Verstraeten, D. Monteyne, C. Kint +4 more
2015mBio23 citations Open access
Semantic Scholar
Structural and biochemical analysis of Escherichia coli ObgE, a central regulator of bacterial persistence
S. Gkekas, R. Singh, A. Shkumatov, J. Messens +4 more
2017Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Structure and mechanism of the 6-oxopurine nucleosidase from Trypanosoma brucei brucei.
An Vandemeulebroucke, C. Minici, I. Bruno, Laura Muzzolini +5 more
2010Biochemistry22 citations
Semantic Scholar
Structural and biochemical analysis of the dual-specificity Trm10 enzyme from Thermococcus kodakaraensis prompts reconsideration of its catalytic mechanism
Ranjan Kumar Singh, A. Feller, M. Roovers, D. Van Elder +3 more
2018RNA: A publication of the RNA Society21 citations Open access
Semantic Scholar
The open reading frame TTC1157 of Thermus thermophilus HB27 encodes the methyltransferase forming N²-methylguanosine at position 6 in tRNA.
M. Roovers, Y. Oudjama, M. Fislage, J. Bujnicki +2 more
2012RNA: A publication of the RNA Society20 citations Open access
Semantic Scholar
Structure of an early native‐like intermediate of β2‐microglobulin amyloidogenesis
Saskia Vanderhaegen, M. Fislage, K. Domanska, W. Versées +3 more
2013Protein Science19 citations Open access
Semantic Scholar
MnmE, a GTPase that drives a complex tRNA modification reaction
M. Fislage, Lina Wauters, W. Versées
201617 citations Open access
Semantic Scholar
Biochemical and kinetic properties of the complex Roco G-protein cycle
Lina Wauters, S. Terheyden, Bernd K. Gilsbach, Margaux Leemans +6 more
2018Biological chemistry15 citations Open access
Semantic Scholar
NrdH-redoxin of Mycobacterium tuberculosis and Corynebacterium glutamicum Dimerizes at High Protein Concentration and Exclusively Receives Electrons from Thioredoxin Reductase*
K. Van Laer, A. Dziewulska, M. Fislage, K. Wahni +6 more
2013Journal of Biological Chemistry13 citations Open access
Semantic Scholar
The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest
Cyrielle I. Kint, N. Verstraeten, I. Wens, Veerle R. Liebens +4 more
2012The FEBS Journal12 citations Open access
Semantic Scholar
Allosteric modulation of the GTPase activity of a bacterial LRRK2 homolog by conformation-specific Nanobodies
Margaux Leemans, C. Galicia, E. Deyaert, Elise Daems +8 more
2020Biochemical Journal11 citations Open access
Semantic Scholar
Biochemical determinants of ObgE‐mediated persistence
N. Verstraeten, S. Gkekas, C. Kint, Babette Deckers +10 more
2019Molecular Microbiology11 citations Open access
Semantic Scholar
A structure of substrate-bound Synaptojanin1 provides new insights in its mechanism and the effect of disease mutations
J. Paesmans, E. Martin, Babette Deckers, M. Berghmans +7 more
2020eLife10 citations Open access
Semantic Scholar
Cryo-TEM structure of β-glucocerebrosidase in complex with its transporter LIMP-2
J. Dobert, Jan-Hannes Schäfer, T. Dal Maso, Priyadarshini Ravindran +8 more
2025Nature Communications9 citations Open access
Semantic Scholar
The LRR-Roc-COR module of the Chlorobium tepidum Roco protein: crystallization and X-ray crystallographic analysis.
E. Deyaert, A. Kortholt, W. Versées
2017Acta Crystallographica Section F Structural Biology Communications9 citations Open access
Semantic Scholar
The role of the essential GTPase ObgE in regulating lipopolysaccharide synthesis in Escherichia coli
Liselot Dewachter, Babette Deckers, Israel Mares-Mejía, Elen Louwagie +8 more
2024Nature Communications7 citations Open access
Semantic Scholar
A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
V. Dederer, Marta Sanz Murillo, Eva P. Karasmanis, Kathryn S. Hatch +12 more
2024Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Nanobody Loop Mimetics Enhance Son of Sevenless 1-Catalyzed Nucleotide Exchange on RAS.
K. Van Holsbeeck, B. Fischer, S. Gonzalez, Charlène Gadais +6 more
2023Angewandte Chemie7 citations Open access
Semantic Scholar
Structure–Activity Relationship (SAR) Study of Spautin-1 to Entail the Discovery of Novel NEK4 Inhibitors
Mathias Elsocht, P. Giron, L. Maes, W. Versées +3 more
2021International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
GTP Binding Is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE
Liselot Dewachter, Babette Deckers, E. Martin, Pauline Herpels +5 more
2019International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function
T. Dal Maso, C. Sinisgalli, Gianluca Zilio, Elisa Franzin +7 more
2025Nature Communications6 citations Open access
Semantic Scholar
Allosteric inhibition of trypanosomatid pyruvate kinases by a camelid single-domain antibody
J. E. Pinto Torres, Mathieu Claes, Rik Hendrickx, M. Yuan +11 more
2024bioRxiv6 citations Open access
Semantic Scholar
Structural and biochemical characterization of the nucleoside hydrolase from C. elegans reveals the role of two active site cysteine residues in catalysis
R. Singh, J. Steyaert, W. Versées
2017Protein Science6 citations Open access
Semantic Scholar
Single time-point analysis of product and substrate inhibition
Olivier Verlaine, R. Malempré, W. Versées, A. Matagne +1 more
2024Scientific Reports5 citations Open access
Semantic Scholar
Allosteric nanobodies to study the interactions between SOS1 and RAS
B. Fischer, T. Uchański, Aidana Sheryazdanova, Simon Gonzalez +10 more
2024Nature Communications5 citations Open access
Semantic Scholar
YbiB: a novel interactor of the GTPase ObgE
Babette Deckers, Silke Vercauteren, Veerke De Kock, C. Martin +9 more
2023Nucleic Acids Research5 citations Open access
Semantic Scholar
Cryo-EM structures of the MnmE–MnmG complex reveal large conformational changes and provide new insights into the mechanism of tRNA modification
Laila Maes, Israel Mares-Mejía, Ella Martin, David Bickel +5 more
2025Nucleic Acids Research4 citations Open access
Semantic Scholar

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