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Bernd K. Gilsbach · SciRah

Researcher profile · Semantic Scholar

Bernd K. Gilsbach

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Bernd K. Gilsbach — researcher profile on SciRah

h-index: 11
Works: 24
Citations: 619

Most-cited papers

Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
Giambattista Guaitoli, Francesco Raimondi, Bernd K. Gilsbach, Y. Gómez-Llorente +18 more
2016Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations
Bernd K. Gilsbach, F. Ho, I. Vetter, P. V. van Haastert +2 more
2012Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
Structural biology of the LRRK2 GTPase and kinase domains: implications for regulation
Bernd K. Gilsbach, A. Kortholt
2014Frontiers in Molecular Neuroscience80 citations Open access
Semantic Scholar
Fluoride complexes of oncogenic Ras mutants to study the Ras-RasGAP interaction
L. Gremer, Bernd K. Gilsbach, Mohammad Reza Ahmadian, A. Wittinghofer
2008Biological chemistry50 citations
Semantic Scholar
Coordinated Ras and Rac Activity Shapes Macropinocytic Cups and Enables Phagocytosis of Geometrically Diverse Bacteria
Catherine M. Buckley, Henderikus Pots, Aurélie Guého, James H. Vines +9 more
2019bioRxiv43 citations Open access
Semantic Scholar
Structural Characterization of LRRK2 Inhibitors.
Bernd K. Gilsbach, A. C. Messias, G. Ito, M. Sattler +3 more
2015Journal of Medicinal Chemistry40 citations Open access
Semantic Scholar
Revisiting the Roco G-protein cycle.
S. Terheyden, F. Ho, Bernd K. Gilsbach, A. Wittinghofer +1 more
2015Biochemical Journal39 citations Open access
Semantic Scholar
Allosteric Inhibition of Parkinson's-Linked LRRK2 by Constrained Peptides.
Leah G. Helton, Ahmed Soliman, Felix von Zweydorf, Michalis Kentros +14 more
2021ACS Chemical Biology29 citations Open access
Semantic Scholar
Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutations
Katharina Rudi, F. Ho, Bernd K. Gilsbach, Henderikus Pots +3 more
2015Bioscience Reports28 citations Open access
Semantic Scholar
Biochemical and kinetic properties of the complex Roco G-protein cycle
Lina Wauters, S. Terheyden, Bernd K. Gilsbach, Margaux Leemans +6 more
2018Biological chemistry15 citations Open access
Semantic Scholar
C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis
Xue-Hua Xu, Henderikus Pots, Bernd K. Gilsbach, D. Parsons +5 more
2022Frontiers in Immunology11 citations Open access
Semantic Scholar
First model of dimeric LRRK2: the challenge of unrevealing the structure of a multidomain Parkinson's-associated protein.
Giambattista Guaitoli, Bernd K. Gilsbach, Francesco Raimondi, C. Gloeckner
2016Biochemical Society Transactions9 citations
Semantic Scholar
Intramolecular feedback regulation of the LRRK2 Roc G domain by a LRRK2 kinase-dependent mechanism
Bernd K. Gilsbach, F. Ho, Benjamin Riebenbauer, Xiaojuan Zhang +3 more
2024bioRxiv8 citations Open access
Semantic Scholar
Regulation of LRRK2: insights from structural and biochemical analysis
Bernd K. Gilsbach, M. Eckert, C. Gloeckner
2018Biological chemistry8 citations
Semantic Scholar
Dictyostelium discoideum: A Model System to Study LRRK2-Mediated Parkinson Disease
A. Kortholt, Bernd K. Gilsbach, P. V. van Haastert
20125 citations Open access
Semantic Scholar
Heterozygous RAB3A variants cause cerebellar ataxia by a partial loss-of-function mechanism.
H. Hengel, Shabab B. Hannan, S. Reich, D. Beijer +31 more
2025Brain : a journal of neurology4 citations Open access
Semantic Scholar
Biochemical and structural characterization of Roco4
Bernd K. Gilsbach
20143 citations
Semantic Scholar
Humanized Roco4 bound to LRRK2-In1
Bernd K. Gilsbach, A. C. Messias, G. Ito, M. Sattler +3 more
20150 citations
Semantic Scholar
Biochemical and Structural Characterization of Roco4. A Model to understand LRRK2 mediated Parkinsons disease.
Bernd K. Gilsbach, A. Wittinghofer
20140 citations
Semantic Scholar
Crystal Structure of the L1180T mutant Roco4 Kinase Domain from D. discoideum bound to AppCp
Bernd K. Gilsbach, I. Vetter, A. Wittinghofer, A. Kortholt
20120 citations
Semantic Scholar
Crystal Structure of the Roco4 Kinase Domain from D. discoideum
Bernd K. Gilsbach, I. Vetter, A. Wittinghofer, A. Kortholt
20120 citations
Semantic Scholar
Crystal Structure of the Roco4 Kinase Domain from D. discoideum bound to the ROCK Inhibitor H1152
Bernd K. Gilsbach, I. Vetter, A. Wittinghofer, A. Kortholt
20120 citations
Semantic Scholar
Crystal Structure of the G1179S Roco4 Kinase Domain bound to AppCp from D. discoideum.
Bernd K. Gilsbach, I. Vetter, A. Wittinghofer, A. Kortholt
20120 citations
Semantic Scholar
Bindungsstudien an αPIX
Bernd K. Gilsbach, M. Ahmadian
20060 citations
Semantic Scholar

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